Page 1,479«..1020..1,4781,4791,4801,481..1,4901,500..»

‘Animal House’ actor Stephen Furst dies from diabetes complications – ABC15 Arizona

Posted: June 18, 2017 at 8:40 pm

Heat Advisoryissued June 18 at 2:48PM MST expiring June 22 at 8:00PM MST in effect for: Apache, Coconino, Navajo, Yavapai

Excessive Heat Warningissued June 18 at 2:48PM MST expiring June 22 at 8:00PM MST in effect for: Coconino, Gila, Yavapai

Excessive Heat Warningissued June 18 at 2:48PM MST expiring June 22 at 8:00PM MST in effect for: Coconino

Excessive Heat Warningissued June 17 at 3:01PM MST expiring June 22 at 8:00PM MST in effect for: Coconino, Gila, Yavapai

Heat Advisoryissued June 17 at 3:01PM MST expiring June 22 at 8:00PM MST in effect for: Yavapai

Heat Advisoryissued June 17 at 3:01PM MST expiring June 22 at 8:00PM MST in effect for: Apache, Coconino, Navajo

Excessive Heat Warningissued June 17 at 2:15AM MST expiring June 22 at 8:00PM MST in effect for: Coconino

Excessive Heat Warningissued June 17 at 2:15AM MST expiring June 22 at 8:00PM MST in effect for: Coconino

Excessive Heat Warningissued June 14 at 2:52PM MST expiring June 20 at 8:00PM MST in effect for: Gila, Yavapai

Excessive Heat Warningissued June 14 at 2:52PM MST expiring June 20 at 8:00PM MST in effect for: Coconino, Yavapai

Excessive Heat Watchissued June 14 at 3:18AM MST expiring June 20 at 8:00PM MST in effect for: Coconino, Gila, Yavapai

Here is the original post:
'Animal House' actor Stephen Furst dies from diabetes complications - ABC15 Arizona

Posted in Diabetes | Comments Off on ‘Animal House’ actor Stephen Furst dies from diabetes complications – ABC15 Arizona

Glow Run fundraiser set for Childhood Diabetes Expense Relief Fund – American Press

Posted: June 18, 2017 at 8:40 pm

JENNINGS The Childhood Diabetes Expense Relief Fund will hold its annual Glow Run on da Bayou 7-10 p.m. Saturday, June 24, at the baseball fields at 1206 East Academy Ave.

The goal of the run, which last year drew over 200 runners and 150 spectators, is to raise money to help families of children with Type 1 diabetes buy insulin and testing supplies and meet other medical needs, said Casey Doucet, local CDERF president.

We hope to see over 500 people this year and would love to see our participants count break the 300 mark. Doucet said. Our main goal, however, is to educate and bring awareness to people locally and have a blast while doing so.

Doucet and his wife, Monique, created CDERF after their son, Wyatt, was diagnosed with Type 1 diabetes in February 2014 at the age of 3.

We had no idea the struggles that we would be facing just trying to keep him alive day after day. After six months of the daily stresses involved with treating our child with this disease, the bills began to roll in, Doucet said.

On top of all the things weve had to deal with, we now had to choose which bill wasnt getting paid this month due to the cost of diabetesrelated medications and supplies. These supplies are literally a matter of life and death, so you do not have the option of not getting them.

The Doucets began discussing ways to help other families facing the same issues, and they hit on the idea of forming the group.

It is our goal that other families do not have to face these circumstances, Doucet said. We feel like if this is the path we are meant to take with Wyatt, then we want to help others who are also facing these difficulties.

The Glow Run is not the main fundraiser for the group, but it is the main public outreach effort, he said.

It allows us to meet people in this area and helps us to raise awareness of this awful disease, Doucet said.

During last years Glow Run, we met several local families who had Type 1 diabetic children. We have been able to help several of them financially, as well as with advice or just an understanding listening ear.

The run will start at the west entrance of the Jennings Park and Recreation parking lot and travel east on East Academy, turning right onto River Oak Drive, circling the subdivision and retracing the route to the starting line.

Registration is available atcderf.org/glowrunthrough midnight June 23 and 5-6 p.m. in the park on race day.

Entry fees are $25 for adults; $20 for children 12-17; $15 for children 7-11; and $10 for non-participants. Children 6 and under enter free.

Awards will be presented to the top three runners in each division, as well as the top male and female in each age group.

Early registrants who sign up before midnight on June 20 will receive a T-shirt, glow items and a water bottle. Participants may also bring their own glow items.

Food and drinks will be provided for all paid participants. Spectators can buy a $10 wristband and eat. Children 6 and under will eat and drink free.

For more information, call CDERF at 337-329-1372 or emailinfo@cderf.org.

Read the rest here:
Glow Run fundraiser set for Childhood Diabetes Expense Relief Fund - American Press

Posted in Diabetes | Comments Off on Glow Run fundraiser set for Childhood Diabetes Expense Relief Fund – American Press

Sherborn’s Jillian Tierney shows how she deals with diabetes – Wicked Local Acton

Posted: June 18, 2017 at 8:40 pm

Ten-year-old Sherborn resident Jillian Tierney was diagnosed with type 1 diabetes in August 2016; when faced with the decision of which charitable organization she would highlight for her fifth-grade Citizenship Project, Tierney chose Joslin Diabetes Center, where she receives her care from Dr. Anat Hanono.

Ten-year-old Sherborn resident Jillian Tierney was diagnosed with type 1 diabetes in August 2016; when faced with the decision of which charitable organization she would highlight for her fifth-grade Citizenship Project, Tierney chose Joslin Diabetes Center, where she receives her care from Dr. Anat Hanono.

Dr. Peter Amenta, president and CEO of Joslin Diabetes Center, joined Jillian and her family at Pine Hill Elementary School for the fifth-grade expo on June 7, where she debuted her project. Tierney showed Amenta her diabetes kit and demonstrated how she uses her glucose monitor, answered questions on the importance of counting carbs, and offered up information and statistics on diabetes for the parents and friends in attendance.

Joslins pediatrics department encourages and allows for young patients to continue pursuing their goals and participating in normal activities as part of learning to incorporate diabetes into their everyday life, and Tierney does not let her recent diagnosis slow her down. She plays soccer, recently finished a spring production of Mulan at a local theater company and will attend coastal ecology camp and a diabetes camp this summer.

For more information, visit http://www.joslin.org.

Here is the original post:
Sherborn's Jillian Tierney shows how she deals with diabetes - Wicked Local Acton

Posted in Diabetes | Comments Off on Sherborn’s Jillian Tierney shows how she deals with diabetes – Wicked Local Acton

Untreated sleep apnea may worsen markers of heart health and … – Washington Post

Posted: June 18, 2017 at 8:40 pm

By Reuters By Reuters June 17

Properly treating a common sleep-related breathing disorder may have benefits for the heart and for blood sugar, a new study suggests.

If people with obstructive sleep apnea dont use machines at night to help keep the airway open, measures of their heart health and blood sugar worsen, researchers found.

One of the long-standing debates in our field is whether sleep apnea causes heart issues and problems with blood sugar or if theyre just associated, said the studys senior author, Jonathan Jun of Johns Hopkins University.

In obstructive sleep apnea, the airway intermittently collapses or becomes blocked during sleep. The blocked airway causes pauses in breathing. Some people address this by using CPAP continuous positive airway pressure machines at night to keep the airway open.

In the past, researchers have tried to directly link sleep apnea with heart health and blood sugar by comparing patients instructed to use CPAP devices with patients instructed to sleep without these machines. But one of the major issues with those studies is that people may not actually use the CPAP machine, Jun said by phone.

For the new study, the researchers recruited 31 people with moderate to severe obstructive sleep apnea who were known to regularly use CPAP machines.

The participants slept two nights in a lab, using their CPAP device on only one of the nights. The researchers obtained blood samples while participants slept.

We are looking at real-time changes, Jun said. Were getting blood every 20 minutes.

As reported in the Journal of Clinical Endocrinology and Metabolism, on the night without CPAP, patients obstructive sleep apnea returned. On those nights, the participants had low levels of oxygen in their blood, poor sleep and an increased heart rate.

Additionally, their blood samples showed increases in fatty acids, sugar and the stress hormone cortisol.

The researchers also saw increases in blood pressure and arterial stiffness, which has been linked with a risk for heart problems.

These were obese patients and patients with relatively severe sleep apnea. They also had other medical problems, Jun pointed out. People who fit that description may be experiencing the same changes if they sleep without using a CPAP machine, he said.

Glucose and fatty acids rose in the overall group without the CPAP machines, but participants with diabetes may be more vulnerable to the glucose elevation, Jun warned.

He said the study cant say what would happen to people with milder sleep apnea.

Because obesity has been tied to an increased risk of sleep apnea, it has been difficult to know whether its sleep apnea or obesity that is causing those problems, Jun noted.

The new study, he said, advances that idea that other conditions and not obesity itself are drivers of those levels.

Read more

Exercise can improve the symptoms of sleep apnea

Snoring may be benign, or it may be a sign of a serious problem

See the original post here:
Untreated sleep apnea may worsen markers of heart health and ... - Washington Post

Posted in Diabetes | Comments Off on Untreated sleep apnea may worsen markers of heart health and … – Washington Post

ASA Provides Input to USDA, FDA on Advances in Biotechnology – KTIC

Posted: June 17, 2017 at 9:42 am

The American Soybean Association (ASA) submitted comments this week to both the U.S. Department of Agriculture (USDA) and the U.S. Food and Drug Administration (FDA) regarding regulations in response to advances in genetic engineering.

ASA included in comments to USDA, that biotechnology is an essential tool in farmers quest to produce enough food to meet the needs of 9.7 billion people by 2050, creating the need for a clear, science-based regulatory system in the U.S. as an example and standard for regulatory systems of biotechnology internationally.

While applauding USDAs efforts to reduce the burden on regulated entities, ASA expressed concern that aspects of the rule as proposed will increase the regulatory burden and stifle research and innovation.

Additionally, ASAs comments to FDA cheered USDAs proposal to exclude certain genome-editing techniques from requiring pre-market approvals because they are low risk and could be found in nature or achieved through traditional breeding methods.

ASA concluded its support saying, Technological advancements such as genome editing offer an additional tool to combat threats while also improving sustainability in production agriculture.

Full comments to USDA and FDA can be found here and here, respectively.

See the original post here:
ASA Provides Input to USDA, FDA on Advances in Biotechnology - KTIC

Posted in Biotechnology | Comments Off on ASA Provides Input to USDA, FDA on Advances in Biotechnology – KTIC

$10M for birthplace of biotechnology – Innovators Magazine

Posted: June 17, 2017 at 9:42 am

(CALIFORNIA)

Thebirthplace of biotechnology is to receive$10 million for a pioneering precision medicine programme.

It was announced this week thatthe California Initiative to Advance Precision Medicine (CIAPM) has been awarded the money from the local governments budget, a decision welcomed by theCalifornia Life Sciences Association (CLSA).

Sara Radcliffe, President & CEO, CLSA, said:California Life Sciences Association (CLSA) applauds Governor Jerry Brown, California State Senate and California Assembly leaders for their strong support of life sciences innovation, as demonstrated again in this years 2017-2018 budget deal which allocates a $10 million investment in precision medicine research. California is the birthplace of biotechnology and today the states life sciences sector employs over 287,200 people working to develop innovative new medicines, technologies and therapies needed to treat and cure patients.

The Californian city of San Diego ishostingtheBIO International Conventionalthe global event for biotechnology next week. It will celebrate the industrys many breakthroughs and on going impact on society.It will take place at the San Diego Convention Center between 19 and 22 June.

BIO International ConventionalCalifornia Initiative to Advance Precision Medicine

Read the rest here:
$10M for birthplace of biotechnology - Innovators Magazine

Posted in Biotechnology | Comments Off on $10M for birthplace of biotechnology – Innovators Magazine

Texas has sanctioned unapproved stem cell therapies. Will it change anything? – Science Magazine

Posted: June 17, 2017 at 9:42 am

Texas Governor Greg Abbott just signed a law making it easier for unproven stem cell therapies to be given to patients in his state.

Marjorie Kamys Cotera/Bob Daemmrich Photography/Alamy Stock Photo

By Kelly ServickJun. 15, 2017 , 11:15 AM

Texas Governor Greg Abbott yesterday signed a bill allowing clinics and companies in the state to offer people unproven stem cell interventions without the testing and approval required under federal law. Like the right to try laws that have sprung up in more than 30 states, the measure is meant to give desperately ill patients access to experimental treatments without oversight from the U.S. Food and Drug Administration (FDA).

In a state where unproven stem cell therapies are already offered widely with little legal backlash, bioethicists and patient advocates wonder whether the states official blessing will maintain the status quo, tighten certain protections for patients, or simply embolden clinics already profiting from potentially risky therapies.

You could make the argument thatif [the new law] was vigorously enforcedits going to put some constraints in place, says Leigh Turner, a bioethicist at the University of Minnesota in Minneapolis, who last year co-authored a study documenting U.S. stem cell clinics marketing directly to consumers online, 71 of which were based in Texas. But it would really be surprising if anybody in Texas is going to wander around the state making sure that businesses are complying with these standards, he adds. Either way, Turner says theres powerful symbolic value in setting up this conflict between state law and federal law.

The law, effective 1 September, will allow people with severe chronic or terminal illness to be treated at a clinic that purports to isolate therapeutic stem cells from adult tissuesuch as a patients own fatif their doctor recommends it after considering all other options, and if its administered by a physician at a hospital or medical school with oversight from an institutional review board (IRB). It also requires that the same intervention already be tested on humans in a clinical trial. The law sanctions a much broader set of therapies than federal rules, which already exempt certain stem cell interventions from FDAs lengthy approval process, provided the cells are only minimally manipulated and perform the same function they normally have in body.

The Texas bills clinical trial and IRB requirements seem to weed out some dubious therapies, but the language is too nebulous to protect patients, says Beth Roxland, a bioethicist at New York Universitys Langone Medical Center in New York City. The bill doesnt specify that a trial be conducted in the United States or that the therapy get clearance from FDA for human testing. You could gain access to something [as long as its] being studied in a human somewhere on the planet, she says, which in the stem cell area makes it really very scary.

Awareness about the risks of unproven stem cell therapies is growing. A case report published in The New England Journal of Medicine earlier this year documented three women who lost their vision after receiving purported stem cell injections meant to treat age-related degeneration of the retina. Such risks are also the subject of a news conference today at the annual meeting of the International Society for Stem Cell Research in Boston.

Roxland is also unnerved by a provision in the Texas law that would prevent any state government entity from interfering with a patients access to treatment. Hypothetically, if a state officially gets wind of nefarious doings at a for-profit clinic the state officials are now restrained from doing anything. She notes that that language mirrors a proposal in a federal bill known as the Trickett Wendler Right to Try Act, introduced in the Senate in January, which would prevent the federal government from interfering with a terminally ill patients access to an experimental drug outside of a clinical trial, and would prevent FDA from considering those patients outcomes in its drug approval decisions. Vice President Mike Pence signaled his support for the law in February and met with the family of Trickett Wendler, who advocated for right to try laws before her death from amyotrophic lateral sclerosis in 2015.

Others also believe that the Texas laws approval might signal a coming thaw in federal regulation of stem cell clinics. The FDA obviously doesnt have the manpower to watch over these people, says David Bales, chairman of the advocacy group Texans for Cures in Austin, which pushed for more patient protections in the new bill. We really feel like theyre trying to open up the floodgates.

See the rest here:
Texas has sanctioned unapproved stem cell therapies. Will it change anything? - Science Magazine

Posted in Cell Medicine | Comments Off on Texas has sanctioned unapproved stem cell therapies. Will it change anything? – Science Magazine

Pierre Coulombe, Ph.D. to lead UM Department of Cell & Developmental Biology – University of Michigan Health System News (press release)

Posted: June 17, 2017 at 9:42 am

ANN ARBOR, MI One of the oldest departments at the University of Michigan is about to get a new leader. The U-M Board of Regents today approved the appointment of Pierre A. Coulombe, Ph.D., to lead the Department of Cell and Developmental Biology in the Medical School.

Coulombe will become chair on August 1, and lead one of the nine basic science departments of Michigan Medicine, U-Ms academic medical center. The departments researchers study how structure governs function in cells and tissues throughout the body, and how complex arrays of signals are integrated to foster the proper development of tissues and organs. They also study stem cells, including embryonic stem cells, and train undergraduate, graduate and medical students in cell biology.

The department traces its roots back to 1854, soon after the founding of the Medical School, when it was known as the Department of Anatomy.

Coulombe comes to Michigan from Johns Hopkins University, where he chaired the Department of Biochemistry and Molecular Biology in the Bloomberg School of Public Health for nine years, and held the E.V. McCollum professorship as well as several joint appointments in the School of Medicine. At Hopkins, Coulombe was noted for recruiting and nurturing junior faculty members to success, and developing robust training programs for graduate students and post-doctoral fellows. He was also instrumental in addressing the departments infrastructure needs.

To me, cell and developmental biology are critically important endeavors as one seeks to translate the wealth of knowledge acquired in biochemistry and molecular biology, along with the power of imaging techniques, into a better understanding of how organs and tissues form, and operate, under normal and disease conditions, he says. This knowledge is also important for developing novel therapies for human disease. U-M already is a formidable institution, and otherwise is making a substantial investment into biomedical research. Therefore, I am absolutely thrilled about the opportunity to lead Cell & Developmental Biology, and team up with my new colleagues in the department and at U-M, to fulfill this potential.

In addition to his appointment in Cell & Developmental Biology, Coulombe will have a joint appointment in the U-M Department of Dermatology. His research focuses on understanding how keratin proteins and the nanoscale filaments they form foster an optimal architecture and function in skin and related epithelia, and how disruption of these processes result in diseases ranging from inherited conditions to cancer.

A native of Montral, Qubec, Coulombe earned his undergraduate degree from the Universit du Qubec Montral and his Ph.D. in Pharmacology from Universit de Montral. He completed his postdoctoral fellowship in the Department of Molecular Genetics and Cell Biology & Howard Hughes Medical Institute at the University of Chicago before joining Johns Hopkins School of Medicine in 1992. He is the author of more than 140 peer-reviewed publications and one book, holds one patent, and has received multiple awards in recognition of his research and teaching endeavors.

For more about the U-M Department of Cell and Developmental Biology, visit https://medicine.umich.edu/dept/cell-developmental-biology.

Continued here:
Pierre Coulombe, Ph.D. to lead UM Department of Cell & Developmental Biology - University of Michigan Health System News (press release)

Posted in Cell Medicine | Comments Off on Pierre Coulombe, Ph.D. to lead UM Department of Cell & Developmental Biology – University of Michigan Health System News (press release)

On the cusp of payoffs for patients, stem cell therapy faces threat from unregulated clinics – STAT

Posted: June 17, 2017 at 9:41 am

TV documentary on pain treatment funded by doctor with

TV documentary on pain treatment funded by doctor with industry ties

For some chronic pain patients, without opioids, life would

For some chronic pain patients, without opioids, life would be torture

Googles bold bid to transform medicine hits turbulence under

Googles bold bid to transform medicine hits turbulence under a divisive CEO

At first meeting of Trumps opioid commission, health advocates

At first meeting of Trumps opioid commission, health advocates plead for Medicaid spending

This bill would reinstate a controversial drug discount for

This bill would reinstate a controversial drug discount for some hospitals

Up and down the ladder: The latest comings and

Up and down the ladder: The latest comings and goings

See original here:
On the cusp of payoffs for patients, stem cell therapy faces threat from unregulated clinics - STAT

Posted in Cell Therapy | Comments Off on On the cusp of payoffs for patients, stem cell therapy faces threat from unregulated clinics – STAT

Broccoli Could Be a Secret Weapon Against Diabetes, Say Scientists – ScienceAlert

Posted: June 17, 2017 at 9:41 am

Broccoli contains an ingredient that can help those with type 2 diabetes control their blood sugar level, according to a new study potentially providing a much-needed treatment option for millions.

A chemical in cruciferous vegetables like broccoli and sprouts calledsulforaphaneis thought to be responsible,having been shown to lower glucose levels in earlier lab experiments on diabetic rats.

To identify suitable compounds to examine, researchers used computer models to identify gene expression changes linked with type 2 diabetes, and then sift through thousands of chemicals that might reverse these changes.

"We're very excited about the effects we've seen and are eager to bring the extract to patients," one of the researchers, Anders Rosengren of the University of Gothenburg in Sweden, told Andy Coghlan at New Scientist.

"We saw a reduction of glucose of about 10 per cent, which is sufficient to reduce complications in the eyes, kidneys and blood."

That 10 percent average reduction was across a sample of 97 human volunteers taking part in a 12-week randomised, placebo-controlled trial. The participants who were obese and who had higher baseline glucose levels to begin with benefitted the most.

The dose was the equivalent of around 5 kilograms (11 pounds) of broccoli daily a fair few platefuls but the researchers say it could be adapted into a powder to add to food or drinks.

It's important to note that all but three of those taking part in the trial continued to take metformin, a drug already used to improve blood sugar regulation in people with diabetes.

However, the researchers think sulforaphane could eventually replace metformin for some patients up to 15 percent of those with diabetes can't take metformin because of the associated risks of kidney damage.

The two chemicals take different approaches: sulforaphane suppresses the enzymes in the liver that stimulate glucose production, whereas metformin makes cells more sensitive to insulin, taking more glucose out of the bloodstream.

With more than 29 million people having type 2 diabetes in the US alone, and that number on the rise, any kind of help is going to be very welcome.

Before the human trial, the researchers also found sulforaphane was able to reduce glucose production in liver cells grown in a lab, and shift liver gene expression away from an abnormal, diseased state in diabetic rats.

Larger and more detailed studies are required before the drug can get approved for regular treatments though, and until then it's probably wise to keep your vegetable intake to a normal, healthy level.

"More research is needed to see if this repurposed drug can be used to treat Type 2 diabetes, as it was only tested in a small number of people and only helped a subset of those who are taking it," Elizabeth Robertson from Diabetes UK, who wasn't involved in the research, told New Scientist.

"For now, we recommend that people continue with the treatment prescribed by their healthcare team."

The findings have been published in Science Translational Medicine.

Continued here:
Broccoli Could Be a Secret Weapon Against Diabetes, Say Scientists - ScienceAlert

Posted in Diabetes | Comments Off on Broccoli Could Be a Secret Weapon Against Diabetes, Say Scientists – ScienceAlert

Page 1,479«..1020..1,4781,4791,4801,481..1,4901,500..»