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Category Archives: West Virginia Stem Cells

Get the 2021 Garden Calendar – West Virginia University

Posted: July 21, 2021 at 2:25 am

The Science of Gardening

The WVU Extension Service Garden Calendar is produced and distributed each year as a service to West Virginias many home gardeners and agricultural producers. The annual calendar is just one of many meaningful projects, programs and outreach efforts provided by WVU Extension Service throughout West Virginias 55 counties.

If you have gardening questions or want more information, please contact your countys WVU Extension Service office. Be sure to check out information for controlling garden pests year-round and related learning activities for even more opportunities.

Enjoy this years Garden Calendar!

Note: To printas many Garden Calendars as existing funds allow, the WVU Extension Service may not be able tohonorweb or email requests for mailed calendars. Please contact your nearest county office to get a calendar. Your understanding is sincerely appreciated.

Companion planting is the practice of growing two or more species of plants that are beneficial to one another in close proximity. There are multiple ways that these plants help one another, including pollination, pest control, habitat for insects, space maximization, natural trellising and increase in crop production.

Some plants provide necessary nutrients that allow other plants to thrive. For example, legumes provide nitrogen compounds to other plants, such as peas and beans planted with corn.

Read about Companion Planting

Light from the sun provides the solar energy used by plants for photosynthesis.Heliotropism, or solar tracking, is when a plant follows the movement of the sun during the day. Rooted in ancient Greek, helio refers to the sun and tropism means a turning or movement of a living organism toward or away from an external stimulus, such as light, heat or gravity.

The sunflower (Helianthus annuus) is the best example of a plant that displays this phenomenon. Young sunflower plants follow the sun from east to west during the day and then, reorient themselves during the night to face east in anticipation of the sunrise.

Read about What is Heliotropism?

Pollination is essential for reproduction in seed-bearing plants, and therefore, much of the foods and ecosystems we enjoy.

Pollination is the physical transfer of pollen from the male anther of a flower to the female stigma. A pollinator is an animal that moves pollen from flower to flower.

Read about The Role of Pollination

Earthworms benefit your garden soil in many ways. These underground excavators burrow channels in soil, making it more porous and improving drainage. They also bring some of the subsoil closer to the surface, mixing it with topsoil and increasing the amount of quality planting soil available.

Earthworms help plants grow by providing better airflow to the roots. Worms excretions are rich in nutrients and bacteria. And, the slimy secretions that earthworms produce contain nitrogen, which also promotes plant growth.

Read about Worms, Worms, Worms

Water is an essential nutrient for plants and comprises up to 95% of a plants tissue. It is required for a seed to sprout, and as the plant grows, water carries nutrients throughout the plant. Water is responsible for several important functions within plant tissues.

Water is necessary for photosynthesis, which is how plants use energy from the sun to create their own food. During this process, plants use carbon dioxide from the air and hydrogen from the water absorbed through their roots and release oxygen as a byproduct. This exchange occurs through pore-like stoma on the leaves.

Read about How Plants Use Water

Germination is the process by which a plant grows from a seed into a seedling. Seeds remain dormant until conditions are favorable for germination. All seeds need water, oxygen and optimal temperature to germinate.

When a seed is exposed to the proper conditions, water and oxygen are taken in through the seed coat. The embryos cells start to enlarge. Then, the seed coat breaks open and the root emerges first, followed by the shoot that contains the leaves and stem.

Read about Germinating Seeds

Dear Friends of WVU Extension Service,

The past year generated a renewed interest in gardening. Seasoned gardeners poured their hearts and souls into perfecting crops, while the more novice gardeners took this opportunity to try home gardening for the first time. Our Family Nutrition Program received more than 25,000 requests for seeds as part of its Grow This! Challenge, and families enjoyed learning about the benefits of gardening.

Read about A Note from the Dean

Seed libraries are a great way to find seeds you need, cant find anywhere else or would like to try. They also provide a wonderful opportunity for you to share extra seeds you have with other growers in your area.

You may be asking yourself what exactly is a seed library. Its just that a library for seeds and can normally be found at your local library.

Read about Seed Libraries

Squash is one of North Americas oldest cultivated crops. It was originally one of three primary crops grown by Native American groups.

Todays squash varieties can be broken up into two main categories: summer and winter. Summer squash includes varieties of yellow squash and zucchini that are picked at an immature stage when the rind is still soft and edible.

Read about Heritage Squash

For centuries, humans have grown grains for food, animal feed and countless other uses. Today, we enjoy our corn roasted, popped, grilled, creamed and made into a longtime favorite of West Virginians, cornbread.

For those wanting that old-timey corn flavor, Golden Bantam is the way to go. This variety is known for early planting and its rich flavor. These stalks only grow to 5 feet tall with two ears that are approximately 6 inches in length. Plant 1 inch deep with 5 to 6 inches between seeds in rows that are 2 to 3 feet apart. When the plants are about 4 inches tall, they will need thinned to 1 foot apart.

Read about Heritage Corn

Melons have long been favored for their sweetness and ease of growing with their cultivation having been documented as far back as ancient Egypt.

Melons are well-suited to West Virginias climate and growing season. They are members of the cucurbit family, which includes squash, gourds and cucumbers. Melons are warm season crops and prefer a sunny location with fertile, well drained soil.

Read about Heritage Melons

Typically, soil moisture is out of our control, unless growing crops in a high tunnel or greenhouse. In a perfect gardening world, it would rain as often as the crops need watered but thats not always the case. Too much water can cause leaching of nutrients and diseases, and not enough water will result in a small harvest or plant death.

If the soil is dry throughout the entire growing season, the best way to retain soil moisture is to amend the top 6 to 12 inches with organic matter, such as grass clippings, worm castings, mushroom compost or straw.

Read about Proper Soil Moisture

Visit your local county office to get a copy of WVU Extension's free Garden Calendar.

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Get the 2021 Garden Calendar - West Virginia University

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Light-Based Therapy Shows Promise in Treating Mucositis in Pediatric Cancer Patients – Cancer Therapy Advisor

Posted: March 11, 2021 at 4:48 am

A new light-based device for wound healing is showing excellent early results in the treatment of mucositis in pediatric cancer patients.1 The therapy, referred to as photobiomodulation, uses low-level lasers in the near-infrared range to stimulate and promote wound healing and regeneration. The device is being studied in the prevention and treatment of mucositis in pediatric cancer patients at West Virginia University (WVU) School of Medicine in Morgantown and other centers in the United States.

Mucositis is characterized by painful and debilitating sores in the mouth, tongue, oropharynx, and throat. It is caused by certain treatments common to cancer regimens, particularly chemotherapeutic agents that preferentially affect fast-dividing cells. Along with the direct effects on the oral cavity, therapy-associated immunosuppression can result in dramatically reduced wound healing. The mucositis generally wont resolve until the immune system recovers, which depending on the type of chemotherapy used, can result in 7 to 14 days of sores and oral pain, said Patrick Tomboc, DO, chief of the Division of Pediatric Hematology-Oncology at WVU, who is using the new light-based device on his pediatric oncology patients.

The pain caused by mucositis can sometimes be so extreme that children require intravenous pain medication and feeding tubes. Aversions to food and oral medication can develop in very young children as a consequence of enduring mucositis-associated pain. Affected children are also at risk for infection via oral sores. Some of the worst mucositis I have seen has been in the setting of bone marrow transplantation. The throat can be so inflamed that the child vomits throat tissue. Mucositis also can lead to serious infections, as the mucosal barriers are often our best way to protect against infection, said Dr Tomboc.

The photobiomodulation device is thought to improve tissue repair by reducing inflammation via reduced oxidative stress in mitochondria.2 The treatment involves inserting a probe-like device into the mouth for 1 to 2 minutes per treatment. It also can be applied on the outside of the skin in very young patients whose oral cavity is too small for the device.

Currently, the device is used prophylactically 3 times a week in patients who are at risk for mucositis or daily as a treatment in those in whom mucositis has developed. Because limitations such as device size exist in the use of photobiomodulation in the pediatric setting, Dr Tomboc and his team are developing a smaller device. It seems to be a painless intervention, and I dont know of any side effects, he explained. The team is planning a prospective study to evaluate photobiomodulation in pediatric cancer patients with mucositis.

In relating observations regarding device efficacy, Dr Tomboc noted that hospitalization time can be greatly reduced. One patient admitted for mucositis was in for 13 days and on patient-controlled analgesia for 10 days. When the same patient was admitted a second time, he was treated with photobiomodulation. Hospital stay was reduced to 4 days, and his mucositis resolved long before his white blood cell counts recovered, said Dr Tomboc. Clinically, the results have been very surprising. Although the number of patients that we have treated so far has been small, we have seen very effective results. We have achieved resolution of mucositis without immune system suppression, he added.

Low-level laser therapy is indicated by a multinational supportive care association for treatment of oral mucositis in adults, explained Geraldine Jacobson, MD, chair of the Department of Radiation Oncology at WVU. We have been using this treatment in the Department of Radiation Oncology since June to reduce oral mucositis in our head and neck cancer patients.

Studies on the benefit in children so far have been inconclusive.3 A clinical trial that is looking at photobiomodulation in pediatric patients who have received hematopoietic stem cell transplants is currently underway (NCT04227340).

Weve seen some amazing responses, said Belinda N. Mandrell, PhD, RN, principal investigator of the clinical trial and director of Division of Nursing Research at St. Jude Childrens Research Hospital in Memphis, Tennessee. We have a few patients who did not get the light therapy with first transplant but did with subsequent transplants. One patient had grade 3 mucositis before light therapy. Following light therapy with second transplant, no mucositis developed at all. The patients and their families are very impressed with the difference that light therapy has made, said Dr Mandrell.

The clinical trial has recruited approximately 60 patients, most of whom have acute lymphoblastic or acute myelogenous leukemia and are undergoing hematopoietic stem cell transplantation. In this trial, the light therapy is being used preventatively, with the results being compared with historical controls. We start the therapy on the first day of conditioning and continue until Day 20 or engraftment is confirmed for 2 consecutive days. Weve treated children as young as 4 months without difficulty, she explained.

Dr Mandrell and colleagues will be doing an interim analysis shortly, with a look at metrics of success, such as days of hospitalization, use of pain medication, and emergence of infections. Although results of the trial are pending, she has been impressed with the therapy so far and hopes that it will become more widely used. After I look at the study data, I want to get the evidence into clinical practice to help prevent oral mucositis. I will then look outside of the hematopoietic stem cell transplant population to other patients, such as those getting high-dose chemotherapy, said Dr Mandrell.

References

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Stem Cell Morgantown West Virginia 26508

Posted: September 14, 2019 at 2:48 am

Stem cell therapy has ended up being a popular argument in the global medical scene. This highly questionable therapy has actually received combined opinions from various stakeholders in the health care industry and has actually likewise drawn in the attention of political leaders, spiritual leaders and the basic population at large. Stem cell treatment is considered a revolutionary treatment for people suffering from a wide range of degenerative conditions. Some common concerns concerning this therapy are addressed below.

Are you a stem cell therapy provider close to Morgantown WV 26508? Contact us for more information about joining our website.

Stem cells can be referred to as blank state or non-specialized cells that have the capability to become customized cells in the body such as bone, muscle, nerve or organ cells. This implies that these unique cells can be utilized to regrow or develop a vast array of damaged cells and tissues in the body. Stem cell therapy is therefore a treatment that targets at attaining tissue regrowth and can be utilized to treat health conditions and diseases such as osteoarthritis, degenerative disc disease, spine injury, muscular degeneration, motor neuron illness, ALS, Parkinsons, heart disease and much more.

Being a treatment that is still under research study, stem cell treatment has not been totally accepted as a sensible treatment alternative for the above mentioned health conditions and illnesses. A lot of studio is currently being performed by researchers and medical specialists in numerous parts of the world to make this treatment practical and reliable. There are nevertheless various restrictions imposed by federal governments on research study including embryonic stem cells.

Presently, there havent been lots of case studies carried out for this type of treatment. However, with the few case studies that have been performed, among the major issues that has actually been raised is the boost in a patients threat of establishing cancer. Cancer is triggered by the rapid reproduction of cells that tend not to pass away so quickly. Stem cells have been associated with comparable growth elements that may cause development of tumors and other cancerous cells in patients.

Contact us for more information about stem cell doctor close to Morgantown WV 26508

Stem cells can be drawn out from a young embryo after conception. These stem cells are commonly referred to as embryonic stem cells. After the stem cells are drawn out from the embryo, the embryo is terminated. This is generally among the significant reasons for debate in the field of stem cell research. Many individuals suggest that termination of an embryo is dishonest and unacceptable.

Stem cells can still be gotten through other means as they can be discovered in the blood, bone marrow and umbilical cords of adult humans. Normal body cells can also be reverse-engineered to become stem cells that have actually limited abilities.

New studio has actually however revealed pledge as scientists target at developing stem cells that do not form into tumors in later treatment phases. These stem cells can for that reason successfully change into other kinds of specialized cells. This treatment is for that reason worth researching into as lots of clients can take advantage of this innovative treatment.

Need a stem cell provider close to Morgantown WV 26508

512

Main address:Morgantown, West Virginia, 26508

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Stem Cell Morgantown West Virginia 26508

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Wei Du | Health Sciences Directory | West Virginia University

Posted: at 2:48 am

Rational identification of a Cdc42 inhibitor presents a new regimen for long-term hematopoietic stem cell mobilization.Liu W,Du W, Shang X, Wang L, Evelyn C, Florian MC, A Ryan M, Rayes A, Zhao X, Setchell K, Meller J, Guo F, Nassar N, Geiger H, Pang Q, Zheng Y.Leukemia. 2019 Mar;33(3):749-761.PMID: 30254339https://www.ncbi.nlm.nih.gov/pubmed/30254339

Mesenchymal COX2-PG secretome engages NR4A-WNT signaling axis in hematopoietic progenitors to suppress anti-leukemia immunity.Wu L, Amarachintha S, Xu J, Oley F Jr,Du W.Br J Haematol. 2018 Nov;183(3):445-456.PMID: 30106181https://www.ncbi.nlm.nih.gov/pubmed/30106181

A non-myeloablative conditioning approach for long-term engraftment of human and mouse hematopoietic stem cells.Du W, Liu W, Mizukawa B, Shang X, Sipple J, Wunderlich M, Geiger H, Davies S, Mulloy J, Pang Q, Zheng Y.Leukemia. 2018 Sep;32(9):2041-2046.PMID: 29959415https://www.ncbi.nlm.nih.gov/pubmed/29959415

Reduced Cell Division Control Protein 42 Activity Compromises Hematopoiesis-Supportive Function of Fanconi Anemia Mesenchymal Stromal Cells.Xu J, Li X, Cole A, Sherman Z, Du W.Stem Cells. 2018 May;36(5):785-795.PMID: 29377497https://www.ncbi.nlm.nih.gov/pubmed/29377497

Cell-Cycle-Specific Function of p53 in Fanconi Anemia Hematopoietic Stem and Progenitor Cell Proliferation.Li X, Wilson AF, Du W, Pang Q.Stem Cell Reports. 2018 Feb 13;10(2):339-346.PMID: 29307578https://www.ncbi.nlm.nih.gov/pubmed/29307578

Immune-DDR crosstalk in pre-leukemia stem cells.Wu L, Cole A, Du W.Oncotarget. 2017 Sep 19;8(47):81731-81732.PMID: 29137216https://www.ncbi.nlm.nih.gov/pubmed/29137216

InVivo RNAi Screen Unveils PPAR as a Regulator of Hematopoietic Stem Cell Homeostasis.Sertorio M, Du W, Amarachintha S, Wilson A, Pang Q.Stem Cell Reports. 2017 May 9;8(5):1242-1255.PMID: 28416286https://www.ncbi.nlm.nih.gov/pubmed/28416286

The immune receptor Trem1 cooperates with diminished DNA damage response to induce preleukemic stem cell expansion.Du W, Amarachintha S, Wilson A, Pang Q.Leukemia. 2017 Feb;31(2):423-433.PMID: 27568523https://www.ncbi.nlm.nih.gov/pubmed/27568523

Deletion of Fanca or Fancd2 dysregulates Treg in mice.Du W, Erden O, Wilson A, Sipple JM, Schick J, Mehta P, Myers KC, Steinbrecher KA, Davies SM, Pang Q.Blood. 2014 Mar 20;123(12):1938-47.PMID: 24501220https://www.ncbi.nlm.nih.gov/pubmed/24501220

Salidroside stimulates DNA repair enzyme Parp-1 activity in mouse HSC maintenance.Li X, Sipple J, Pang Q, Du W.Blood. 2012 May 3;119(18):4162-73.PMID: 22427203https://www.ncbi.nlm.nih.gov/pubmed/22427203

The immune receptor Trem1 cooperates with diminished DNA damage response to induce preleukemic stem cell expansion.Du W, Amarachintha S, Wilson A, Pang Q.Leukemia. 2017 Feb;31(2):423-433.PMID: 27568523https://www.ncbi.nlm.nih.gov/pubmed/27568523

Deletion of Fanca or Fancd2 dysregulates Treg in mice.Du W, Erden O, Wilson A, Sipple JM, Schick J, Mehta P, Myers KC, Steinbrecher KA, Davies SM, Pang Q.Blood. 2014 Mar 20;123(12):1938-47.PMID: 24501220https://www.ncbi.nlm.nih.gov/pubmed/24501220

Salidroside stimulates DNA repair enzyme Parp-1 activity in mouse HSC maintenance.Li X, Sipple J, Pang Q, Du W.Blood. 2012 May 3;119(18):4162-73.PMID: 22427203https://www.ncbi.nlm.nih.gov/pubmed/22427203

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Stem Cell Charleston West Virginia 25314

Posted: February 24, 2019 at 3:43 pm

Stem cell therapy has actually ended up being a popular debate in the international medical scene. This extremely controversial treatment has actually received mixed opinions from different stakeholders in the healthcare industry and has likewise drawn in the interest of politicians, spiritual leaders and the basic population at large. Stem cell therapy is thought about an innovative treatment for individuals struggling with a large range of degenerative conditions. Some typical concerns regarding this treatment are answered below.

Are you a stem cell therapy doctor in Charleston WV 25314? Contact us for more information about joining our website.

Stem cells can be described as blank state or non-specialized cells that have the capability to become specific cells in the body such as bone, muscle, nerve or organ cells. This means that these unique cells can be utilized to restore or develop a wide variety of broken cells and tissues in the body. Stem cell treatment is therefore a treatment that targets at attaining tissue regeneration and can be used to cure health conditions and diseases such as osteoarthritis, degenerative disc disease, spine injury, muscular degeneration, motor nerve cell illness, ALS, Parkinsons, cardiovascular disease and a lot more.

Being a treatment that is still under research study, stem cell treatment has actually not been totally accepted as a practical treatment choice for the above discussed health conditions and illnesses. A great deal of research study is currently being performed by scientists and medical professionals in various parts of the world to make this treatment viable and effective. There are nevertheless various limitations enforced by federal governments on research including embryonic stem cells.

Presently, there have not been numerous case studies performed for this kind of treatment. Nevertheless, with the few case studies that have actually been performed, one of the significant issues that has actually been raised is the increase in a clients risk of developing cancer. Cancer is caused by the quick reproduction of cells that have a tendency not to pass away so quickly. Stem cells have been associated with similar development factors that might lead to formation of tumors and other malignant cells in patients.

Contact us for more information about stem cell provider in Charleston WV 25314

Stem cells can be extracted from a young embryo after conception. These stem cells are commonly described as embryonic stem cells. After the stem cells are drawn out from the embryo, the embryo is ended. This is generally among the major reasons for controversy in the field of stem cell research. Many individuals say that termination of an embryo is dishonest and inappropriate.

Stem cells can still be obtained through other means as they can be discovered in the blood, bone marrow and umbilical cables of adult human beings. Typical body cells can likewise be reverse-engineered to become stem cells that have limited capabilities.

New research study has actually however shown pledge as scientists target at developing stem cells that do not form into growths in later treatment stages. These stem cells can for that reason effectively transform into other kinds of specialized cells. This therapy is for that reason worth researching into as numerous patients can benefit from this advanced treatment.

stem cell doctor in Charleston WV 25314

512

Main address:Charleston, West Virginia, 25314

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Stem Cell Charleston West Virginia 25314

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Stem Cell Charleston West Virginia 25350

Posted: November 21, 2018 at 10:48 am

Stem cell therapy has actually become a popular debate in the global medical scene. This extremely controversial treatment has received mixed viewpoints from numerous stakeholders in the health care industry and has likewise attracted the interest of politicians, religious leaders and the general population at large. Stem cell treatment is thought about an innovative treatment for individuals suffering from a wide range of degenerative conditions. Some typical questions regarding this treatment are addressed below.

Are you a stem cell therapy doctor in Charleston WV 25350? Contact us for more information about joining our website.

Stem cells can be described as blank state or non-specialized cells that have the ability to become specific cells in the body such as bone, muscle, nerve or organ cells. This indicates that these unique cells can be used to restore or establish a wide variety of broken cells and tissues in the body. Stem cell treatment is for that reason a treatment that targets at accomplishing tissue regeneration and can be used to treat health conditions and diseases such as osteoarthritis, degenerative disc disease, spine injury, muscular degeneration, motor nerve cell illness, ALS, Parkinsons, cardiovascular disease and many more.

Being a treatment that is still under research study, stem cell treatment has actually not been totally accepted as a practical treatment option for the above discussed health conditions and diseases. A great deal of research study is currently being performed by scientists and medical specialists in numerous parts of the world to make this treatment practical and effective. There are nevertheless numerous constraints imposed by governments on research including embryonic stem cells.

Currently, there have not been many case studies carried out for this type of treatment. Nevertheless, with the few case studies that have been performed, one of the significant issues that has actually been raised is the boost in a patients danger of establishing cancer. Cancer is triggered by the rapid reproduction of cells that have a tendency not to pass away so easily. Stem cells have been related to comparable growth aspects that might result in development of growths and other malignant cells in clients.

Contact us for more information about stem cell doctor in Charleston WV 25350

Stem cells can be extracted from a young embryo after conception. These stem cells are typically described as embryonic stem cells. After the stem cells are drawn out from the embryo, the embryo is ended. This is basically among the significant reasons for controversy in the field of stem cell research study. Many people suggest that termination of an embryo is unethical and inappropriate.

Stem cells can still be obtained through other ways as they can be found in the blood, bone marrow and umbilical cords of adult people. Regular body cells can also be reverse-engineered to become stem cells that have actually restricted capabilities.

New studio has actually however revealed promise as scientists target at establishing stem cells that do not form into tumors in later treatment phases. These stem cells can for that reason successfully change into other kinds of specialized cells. This treatment is therefore worth investigating into as numerous clients can gain from this revolutionary treatment.

stem cell doctor near Charleston WV 25350

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Main address:Charleston, West Virginia, 25350

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Stem Cell Charleston West Virginia 25350

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Stem Cell Martinsburg West Virginia 25403

Posted: July 25, 2018 at 7:49 pm

Stem cell therapy has become a popular argument in the international medical scene. This highly questionable treatment has actually received blended opinions from numerous stakeholders in the healthcare industry and has actually also brought in the attention of politicians, religious leaders and the general population at large. Stem cell treatment is considered an innovative treatment for individuals dealing with a wide variety of degenerative conditions. Some typical questions concerning this treatment are answered listed below.

Are you a stem cell therapy specialist in Martinsburg WV 25403? Contact us for more information about joining our website.

Stem cells can be referred to as blank state or non-specialized cells that have the ability to become customized cells in the body such as bone, muscle, nerve or organ cells. This indicates that these special cells can be used to regrow or develop a large range of damaged cells and tissues in the body. Stem cell therapy is for that reason a treatment that aims at achieving tissue regeneration and can be utilized to treat health conditions and illnesses such as osteoarthritis, degenerative disc disease, spine injury, muscular degeneration, motor nerve cell disease, ALS, Parkinsons, cardiovascular disease and much more.

Being a treatment that is still under studio, stem cell treatment has actually not been fully accepted as a viable treatment choice for the above pointed out health conditions and health problems. A lot of studio is presently being carried out by scientists and medical professionals in various parts of the world to make this treatment practical and efficient. There are nevertheless different limitations imposed by federal governments on research including embryonic stem cells.

Currently, there havent been numerous case studies performed for this kind of treatment. However, with the few case studies that have been performed, one of the significant issues that has been raised is the increase in a clients threat of developing cancer. Cancer is triggered by the fast multiplication of cells that tend not to pass away so quickly. Stem cells have been related to comparable growth factors that might result in development of tumors and other malignant cells in patients.

Contact us for more information about stem cell provider in Martinsburg WV 25403

Stem cells can be extracted from a young embryo after conception. These stem cells are typically described as embryonic stem cells. After the stem cells are extracted from the embryo, the embryo is terminated. This is essentially among the significant reasons for controversy in the field of stem cell research study. Lots of people argue that termination of an embryo is unethical and unacceptable.

Stem cells can still be gotten through other methods as they can be discovered in the blood, bone marrow and umbilical cords of adult human beings. Typical body cells can also be reverse-engineered to become stem cells that have limited capabilities.

New studio has nevertheless revealed promise as researchers focus on establishing stem cells that do not form into growths in later treatment stages. These stem cells can therefore efficiently transform into other types of specialized cells. This therapy is therefore worth investigating into as lots of clients can take advantage of this advanced treatment.

Find a stem cell provider near Martinsburg WV 25403

512

Main address:Martinsburg, West Virginia, 25403

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Stem Cell Martinsburg West Virginia 25403

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FDA Cracks Down On Stem-Cell Clinics Selling Unapproved Treatments – West Virginia Public Broadcasting

Posted: September 2, 2017 at 5:45 am

The Food and Drug Administration is cracking down on "unscrupulous" clinics selling unproven and potentially dangerous treatments involving stem cells.

Hundreds of clinics around the country have started selling stem cell therapies that supposedly use stem cells but have not been approved as safe and effective by the FDA, according to the agency.

"There are a small number of unscrupulous actors who have seized on the clinical promise of regenerative medicine, while exploiting the uncertainty, in order to make deceptive, and sometimes corrupt assurances to patients based on unproven and, in some cases, dangerously dubious products," FDA Commissioner Scott Gottlieb said in a statement Monday.

The FDA has taken action against clinics in California and Florida.

The agency sent a warning letter to the US Stem Cell Clinic of Sunrise, Fla., and its chief scientific officer, Kristin Comella, for "marketing stem cell products without FDA approval and significant deviations from current good manufacturing practice requirements."

The clinic is one of many around the country that claim to use stem cells derived from a person's own fat to treat a variety of conditions, including Parkinson's disease, amyotrophic lateral sclerosis (ALS), and lung and heart diseases, the FDA says.

The Florida clinic had been previously linked to several cases of blindness caused by attempts to use fat stem cells to treat macular degeneration.

The FDA also said it has taken "decisive action" to "prevent the use of a potentially dangerous and unproven treatment" offered by StemImmune Inc. of San Diego, Calif., and administered to patients at California Stem Cell Treatment Centers in Rancho Mirage and Beverly Hills, Calif.

As part of that action, the U.S. Marshals Service seized five vials of live vaccinia virus vaccine that is supposed to be reserved for people at high risk for smallpox but was being used as part of a stem-cell treatment for cancer, according to the FDA. "The unproven and potentially dangerous treatment was being injected intravenously and directly into patients' tumors," according to an FDA statement.

Smallpox essentially has been eradicated from the planet, but samples are kept in reserve in the U.S. and Russia, and vaccines are kept on hand as a result.

But Elliot Lander, medical director of the California Stem Cell Treatment Centers, denounced the FDA's actions in an interview with Shots.

"I think it's egregious," Lander says. "I think they made a mistake. I'm really baffled by this."

While his clinics do charge some patients for treatments that use stem cells derived from fat, Lander says, none of the cancer patients were charged and the treatments were administered as part of a carefully designed research study.

"Nobody was charged a single penny," Lander says. "We're just trying to move the field forward."

In a written statement, U.S. Stem Cell also defended its activities.

"The safety and health of our patients are our number one priority and the strict standards that we have in place follow the laws of the Food and Drug Administration," according to the statement.

"We have helped thousands of patients harness their own healing potential," the statement says. "It would be a mistake to limit these therapies from patients who need them when we are adhering to top industry standards."

But stem-cell researchers praised the FDA's actions.

"This is spectacular," says George Daley, dean of the Harvard Medical School and a leading stem-cell researcher. "This is the right thing to do."

Daley praised the FDA's promise to provide clear guidance soon for vetting legitimate stem-cell therapies while cracking down on "snake-oil salesmen" marketing unproven treatments.

Stem-cell research is "a major revolution in medicine. It's bound to ultimately deliver cures," Daley says. "But it's so early in the field," he adds. "Unfortunately, there are unscrupulous practitioners and clinics that are marketing therapies to patients, often at great expense, that haven't been proven to work and may be unsafe."

Others agreed.

"I see this is a major, positive step by the FDA," says Paul Knoepfler, a professor of cell biology at the University of of California, Davis, who has documented the proliferation of stem-cell clinics.

"I'm hoping that this signals a historic shift by the FDA to tackle the big problem of stem-cell clinics selling unapproved and sometimes dangerous stem cell "treatments" that may not be real treatments," Knoepfler says.

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Kayhi grad represents Alaska at national camp – Ketchikan Daily News

Posted: at 5:45 am

Kayhi grad represents Alaska at national camp

By ALAINA BARTELDaily News Staff Writer

Class of 2017 Ketchikan High School graduate and Syracuse University freshman Cameron Edwards represented Alaska and Ketchikan at the 2017 National Youth Science Camp in Green Bank, West Virginia, this summer.

Edwards, who is studying to be an environmental engineer, joined 108 other delegates from 50 states and eight countries in the prestigious annual STEM (science, technology, engineering and mathematics) program. The event takes place in the Monongahela National Forest and provides learning opportunities through STEM presentations and outdoor activities.

We had some really cool presenters come, like the chief scientist for the International Space Station came, and one of the guys that helped pioneer stem cell research came and he talked about stem cells, Edwards said.

As a part of the event, the students travel to the nations capitol in Washington D.C., which is only five hours away from the camp. Each year, West Virginias senior member of the United States Senate honors the delegates with a luncheon attended by other members of the U.S. government.

We heard John McCain talk. We went to the senate building and theres a senate luncheon, and all of the senators are invited but it was the day that they were voting on the health care bill, so no one really came, Edwards said. Our nurse went and she was trying to find senators to come and talk and she found John McCain, he was walking out of the bathroom.

For nearly a month, the delegates attended lectures but also experienced the beauty of the West Virginia outdoors through backpacking, caving, mountain biking and rock climbing. Edwards said she particularly enjoyed the outdoor activities, but also learned a lot at the event.

At her favorite presentation, which she said wasnt necessarily scientific but rather related to the scientific community, she learned about teaching. Specifically, the lecturer talked about how to look at information and to question everything that they read, and how to change someones perspective, and what they believe to be true, without saying theyre wrong.

The camp is attended by graduating high school seniors with high achievements in STEM fields. The future STEM leaders are selected on merit, with the program provided to them at no cost, including travel, removing any financial barriers for attendance, according to a statement from the NYSC.

This is a unique experience for these amazing students and one that can impact them for the rest of their lives, John Giroir, director of the NYSC, said in a statement. Cameron is (an) excellent example of the kind of student who participates and goes on to significant achievements in the STEM fields.

The National Youth Science Camp is operated by the National Youth Science Foundation. To apply for the NYSC, visit http://www.apply.nysc.org. To learn more about the programs and work of the NYSF, visit http://www.nysf.com.

A couple of people from Ketchikan have gone. Its for graduating seniors, I would just encourage them to apply, she said. Its a lot of fun, I made a lot of friends and I made a lot of connections that will last me a lifetime. Its such a big community of people, Im really glad I went and Im glad I applied.

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Hispanics left out of clinical trials and cutting-edge treatments – Wisconsin Gazette

Posted: August 12, 2017 at 6:40 am

Two decades ago, Luis Antonio Cabrera received devastating news: He likely had only three months to live.

The Puerto Rican truck driver, then 50, had attributed his growing leg pain to spending so many hours on the road. The real culprit was a malignant tumor in his left kidney that was pressing on nerves from his lower spine.

His initial treatment involved removing the organ, a complex surgery that proved insufficient, as the cancerous cells had already spread to his lungs. His primary care physician in Puerto Rico contacted doctors at the National Institutes of Health, in Bethesda, Maryland, to enroll Cabrera in a medical study to test an innovative therapy: transplanting blood stem cells to destroy the cancer cells.

Today, at 70, Cabrera a father of five and grandparent who moved to West Virginia with his wife to be closer to NIH feels strong and healthy.

I come to do tests every six months Im like a patient at large, he said.

However, Cabrera is one of a relatively small number of Hispanics who participate in clinical trials.

Less than 8 percent of enrollees are Hispanic, even though Hispanics comprise 17 percent of the population, said Dr. Eliseo Prez-Stable, director of NIHs National Institute on Minority Health and Health Disparities.

That means not only do Hispanics have less access to experimental, cutting-edge treatments, but also that researchers have less data on how a drug works in that population.

Studies have shown that different ethnic groups can respond differently to the same treatment.

The lack of patients from minority groups is an endemic problem in clinical trials; minorities typically are represented at a very low rate.

Studies should represent the demographics of the country, said Dr. Jonca Bull, an assistant commissioner on minority health at the U.S. Food and Drug Administration. We need to close that gap so we can better understand how a particular drug or therapy works in different communities.

There are many reasons why Hispanic people do not enroll in these studies, Prez-Stable said: lack of information, disparities in access to health care and lack of fluency in English are among main factors.

Dr. Otis Brawley, chief medical officer with the American Cancer Society, said Latinx families are open to participating in clinical trials, especially to help treat a sick son or daughter, but they need a doctor to initiate and navigate the process.

Federal officials aim to augment Hispanic enrollment in clinical trials.

In March, the FDA launched a campaign to educate Hispanics about medical studies. Primary care physicians have to be the champions. In addition, the community health centers can help, because they are places of care that people trust, said Bull.

As of early July, there were 94,545 ongoing clinical trials in the United States, according to the NIHs official website, clinicaltrials.gov. As in Cabreras case, the primary physician usually helps a patient find a medical study, although the advent of the internet in recent decades has meant a growing number of patients discover trials themselves online.

The American Cancer Society also has an information service to help patients find clinical trials that match their medical condition. This service is available in Spanish.

To participate in a trial, a person must meet the researchers criteria for eligibility, including factors like age, gender or condition. Often, the center conducting the study covers related costs of drugs, treatments and tests.

For Brenda Aldana, receiving care at Holy Cross Hospital in Silver Spring, Maryland, made all the difference.

Aldana, 34, arrived in the United States from El Salvador nine years ago. During her first year here, she felt tired and her hair began to fall out. She initially thought those were symptoms of the stress of starting a new life in a new country, but while visiting her sister in Frederick, Maryland, Aldana fainted. It turned out she was suffering more than nerves: She had a pulmonary embolism.

Within two weeks of tests, she was diagnosed with lupus, a debilitating chronic condition with a high incidence among Latinas.

At Holy Cross, the doctors told me that they were going to help me get into a medical program for a medication to treat arthritis (caused by her lupus), said Aldana, who has three children, ages 17, 6 and 5.

Aldana travels from Olney, Maryland, to the NIH Clinical Center once a month to receive intravenous medication.

These days, Hispanics receive less quality medical care, so its important for them to be more involved in clinical trials, said Brawley, noting that enrolling in a clinical trial gives patients access to high-quality physicians they might not otherwise see.

In a medical study, instead of having the opinion of a single doctor, youll get the opinion of a group of highly qualified doctors who can say, This is good for people like you, Brawley said.

John Vasquez, 21, of San Antonio, Texas, needed only internet access and a cellphone to find the medical study that could change his life.

In September 2015, while on his way to his brothers football game, he lost feeling in his leg, arm and the right side of his face. I thought I was having a stroke, he said.

He had aplastic anemia, a potentially deadly, rare blood disorder that was destroying his red and white cells and his platelets, which aid the bodys clotting mechanism.

In a Facebook group for people with severe blood conditions, he was advised to contact the NIH, which sent him a kit for blood tests. After analyzing his clinical history, they told him he was eligible to participate in a medical study, which opened the gates to an innovative transplant that could change the course of his disease. Temporarily living with a sister in Maryland, he was scheduled for a bone marrow transplant this month. His donor: his 14-year-old brother.

Kaiser Health News is a national health policy news service. It is an editorially independent program of the Henry J. Kaiser Family Foundation.

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