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Is stem cell therapy approved in Singapore? – The Straits Times

Posted: July 1, 2017 at 6:45 pm

Reader Charles Wang wrote to ask if stem cell therapy - the use of stem cells to treat various medical conditions - is approved in Singapore. Mr Wang also asked where one could seek this treatment if it is available. Health reporter Linette Lai answered.

Any new treatment must be backed up by sufficient scientific evidence to ensure that it is safe and effective. However, there is still not enough scientific evidence available for stem cell therapy to be approved as a mainstream treatment in Singapore.

A Ministry of Health spokesman said: "To date, stem cell therapy has not been substantiated by sufficient clinical evidence as a form of mainstream treatment for any diseases or ailments, and it is not available as a treatment in our public hospitals.

"If any registered medical practitioners or institutions want to administer stem cells as a form of medical treatment, it would have to be conducted within the context of clinical trials."

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Is stem cell therapy approved in Singapore? - The Straits Times

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Anger as Scots patients miss out on ‘breakthrough’ stem cell therapy … – Herald Scotland

Posted: July 1, 2017 at 6:45 pm

LUCY Clarke was facing a downhill spiral when she flew to Russia to undergo a cutting edge stem cell transplant.

Two years on she says the procedure not only halted her illness in its tracks, but reversed much of the damage inflicted by multiple sclerosis.

The 41-year-old from Inverness is now backing crowdfunding efforts so that her friend and neighbour, Rona Tynan, can receive the same life-changing operation in Mexico before she becomes too ill to qualify.

Mrs Tynan, 50, has until the end of August to raise the 60,000 needed.

However, both are angry at a cross-border divide which means that a small number of MS patients in England can undergo the treatment for free on the NHS, while in Scotland despite having some of the highest rates of MS in the world the health service has refused patients' funding and no clinical trials are planned.

Mrs Clarke, a chemistry graduate and acupuncturist, began investigating AHSCT (autologous haematopoietic stem cell transplantation) in 2014 after her condition progressed from relapsing-remitting to secondary progressive MS. At the time her son was three and she feared ending up in a wheelchair.

Although the treatment has been available overseas for decades, it has never been routinely available on the NHS and is considered unproven by many neurologists.

It is also a highly aggressive therapy, using intensive chemotherapy to strip out sufferers faulty immune systems before replenishing it with stem cells harvested from their own bone marrow or donor tissue. Despite the risks, many patients including Mrs Clarke credit it with transforming their lives.

She underwent the procedure in Moscow over a period of four weeks in April and May 2015. She said: From when my son was three to when I had the transplant, my walking had deteriorated, I needed to use a walking stick all the time, I had very poor balance, debilitating fatigue, I had brain fog, I used to slur my words.

"Im left-handed and my left hand was really weak so my writing was bad. Other things would come and go numbness in my legs, tingling, cramps in my calves, sore and painful legs. The majority of them have gone since the transplant.

I noticed quite quick improvements in things like balance. The biggest thing is not really having fatigue, and the brain fog completely went. I stopped slurring my words quite quickly after treatment. I was more alert. I had more concentration, more focus. Within six months the shaking in my left arm had gone. Ive still got drop foot in my right leg and I still use a walking stick, but once youve got to the stage of secondary progressive it all gets a bit scary. Things are going downhill and youre told theres nothing that can be done, so really my goal from treatment was just to halt the progression to know I wasnt getting any worse. Thankfully, and luckily, I have seen lots of benefits.

Eighteen months on, MRI brain scans show no signs of disease progression and while Mrs Clarke stresses that the treatment is neither a magic bullet nor a walk in the park, she is supporting Rona Tynans bid to undergo the same surgery in October.

Mrs Tynan, a retired Metropolitan police sergeant and mother-of-two from Inverness, also has secondary progressive MS. She is already in a wheelchair and fears that unless she undergoes the treatment soon she will become too ill. She said: Im a 7.5 out of 10 on the disease progression scale, where 10 is death. Most clinics stop taking you at seven, but Mexico just raised it to 8.5. Thats brilliant for people like myself, but I cant afford to get any more ill.

So far, Mrs Tynans fundraising page on JustGiving has raised nearly 4000, but she is frustrated that more is not being done to help Scottish patients. In England, clinical trials are ongoing in London and Sheffield but a small number of patients with relapsing-remitting MS can be referred for the treatment off-trial, for free, on the NHS. In Scotland, however, eligible patients have been turned down for NHS funding.

Mrs Tynan said: It seems crazy to me that Brits are going to Chicago and Mexico and Russia for a treatment that in the long-run could save the NHS loads of money. Scotland is one of the worst places in the world for MS yet in England you can get this treatment for free. Why arent we fighting in Scotland to get this?

Mrs Clarke added: Its very unfair. It just seems a no brainer to me why they wouldnt make it available not for all patients but for some. The Scottish Government said referral decisions were "for clinicians".

A spokesman said: "Whilst the vast majority of healthcare provided by NHS Scotland is delivered in Scotland, NHS boards can commission treatment in other countries on an ad hoc basis, particularly where highly specialised treatment is involved. Decisions to refer patients are for clinicians, based on agreed guidelines, which ensure best practice, equity of access and consistency of treatment for all patients.

"HSCT is not currently widely available anywhere on the NHS, but people from Scotland can participate in trials held in other centres across the UK, where clinically determined appropriate and beneficial."

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Anger as Scots patients miss out on 'breakthrough' stem cell therapy ... - Herald Scotland

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Damaged bone or cartilage? Now, grow your own cells in a lab – Hindustan Times

Posted: July 1, 2017 at 6:45 pm

When 14-year-old Aarav Gulati (name changed on request) met with an accident a couple of years ago while playing football, he injured his knee. A portion of the cartilage was damaged, and doctors used turned to a radical new procedure for a solution. They took Gulatis own cells, grew them in a lab and used them to replace the cartilage and repair the damage in a natural way.

He was an ideal case for the use of regenerative cell therapy that was a fairly new phenomenon in orthopaedic treatment in India, says Dr Yash Gulati, senior joint replacement and spine surgeon, New Delhis Indraprastha Apollo Hospital.

The regenerative cell therapy got US FDA approval this year, and the Apollo group partnered with RMS REGROW, a company that specialises in cell therapy technology, to exclusively offer the treatment to patients in India.

Instead of using artificial implants, the technique helps in healing the bone or cartilage damage in a natural way using a persons own cells to regain normal function. Cultured cells (grown in a lab) are injected into a patient to replace diseased or dysfunctional cells.

Instead of using artificial implants, the technique helps in healing the bone or cartilage damage in a natural way using a persons own cells to regain normal function. Cultured cells (grown in a lab) are injected into a patient to replace diseased or dysfunctional cells. (Illustration: Siddhant Jumde)

A small part of the joint cartilage is taken through a keyhole procedure, and is grown in a special manner to convert it into stem cells in the laboratory, says Dr Gulati. This is then applied on the area showing loss of joint cartilage.

Dr Gulati has so far treated 10 people using this therapy in Apollo, Delhi.

Stem cells lead to growth of joint cartilage in defective areas, and normal new cartilage re-grows. In bone damage, bone marrow cells are harvested, cultured and implanted in the area to be able to re-grow in a healthy way, Dr Gulati says.

In Mumbai, those in need of joint replacement because of injury, wear and tear or other lifestyle and ageing, are also realising that new cartilage can be grown in a lab from ones own cells and used instead of artificial materials.

Chondron or cartilage cell therapy is a patient-specific regenerative medical treatment which naturally regrows original cartilage. The therapy is used for repairing articular cartilage of the knee, ankle and shoulder joints and to help replace missing areas of cartilage.

This is a process where a biopsy of cartilage cells (chondrocytes) is taken from the patients knee, ankle or shoulder, says Satyen Sanghavi, chief scientific officer of Regenerative Medical Services Regrow, a biotechnology company in Mumbai.

Causes of bone or cartilage damage

They are then cultured to grow and multiply in a lab for 3-4 weeks into a surplus population of several million. The cultured cells are then re-implanted in the damaged area in a minimally invasive surgical procedure.

The process comes from eight years of work in cell and tissue therapy research. Chondron ACI is the countrys first cell therapy product.

These cells grow and repair tissue with properties similar to that of normal cartilage present in other joints, says Sanghavi. But replacement alone doesnt solve problems. Patients are expected to follow a rehabilitation program, to help the body adjust to new cells and them get back to day-to-day physical.

Its easy to see the advantages of a process like this. Experts say it may avoid the need for future prosthetic joints replacement (especially partial joint replacement) and allows patients the freedom to continue physical activities as before.

It also poses less risk of disease transmission or infection since it comes from the patients own tissue (no foreign material or metal goes inside the body). It may also halt further progression to osteoarthritis, a common problem with those in need of joint replacement.

The procedure costs Rs.3 to 3.5 lakhs.

In India, more than 500 patients have been treated with both bone and cartilage cell therapy procedures, says Sanghavi.

There is a success rate of more than 95%. During our clinical trials and research, we have treated working professionals, housewives, athletes, army men and mountaineers. Almost all of them have successfully recovered and got back to their active life.

However, this new technique has a flip side, too.

The price could be a bit steep for some because stem cell treatment is expensive; and the treatment gets prolonged as a patient has to wait for some time as cell culture takes time and one cannot bear weight on the affected area while the healing is on. Also, not all patients are suitable for it because it can correct only if damage isnt extensive, says Dr Ankit Goyal, associate professor, Safdarjung Sports Injury Centre (SIC) in Delhi.

Safdarjung Hospital had also treated about 35 patients, who had damaged their cartilage, with the technique a few years ago.

We would send cartilage for culture but only in cases where damage was limited. This is definitely not a substitute for knee or hip replacement procedure where the entire joint is extensively damaged. However, it may prevent the need for replacement later on in life, especially in young patients, he says.

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Damaged bone or cartilage? Now, grow your own cells in a lab - Hindustan Times

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Dr. Rath’s New O-Shot Uses Fat Cells to Shatter the Gender Orgasm Gap & Eliminate Urinary Leakage for Women – PR Web (press release)

Posted: July 1, 2017 at 6:44 pm

Dr. Stephen A. Rath, Fusion Medical Spa & Wellness in Ruidoso, New Mexico

Ruidoso, New Mexico (PRWEB) June 26, 2017

A new and improved Orgasm-Shot addressing female sexual dysfunction, anorgasmia, and urinary leakage is revolutionizing the way women look and feel about themselves and their sexual encounters. A unique medical practice in New Mexico is tackling the problem of female sexual dysfunction and urinary leakage head on with a ground breaking medical technique aimed to give women the pleasurable experiences they desire! Women are happy to repurpose fat cells from their bellies to their vaginas in an effort to increase sensation, orgasm frequency, and eliminate bladder leakage all done in office.

At Fusion Medical Spa & Wellness in Ruidoso, New Mexico, Dr. Stephen A. Rath is turning to the very latest in non-surgical aesthetic medicine to address sexual concerns for women. Dr. Rath is one of the countrys premier providers of Autologous Lipocyte Micronized Injection (ALMI). This ground breaking procedure allows Dr. Rath to use a patients own adipose (fat) tissue to restore volume, texture, tone and sensation to the vaginal area. This revolutionary rejuvenation procedure restores function, while repairing and regenerating damaged tissue.

During the ALMI procedure done in office at Fusion Medical Spa & Wellness, the fat tissue is typically collected from the lower abdomen in less than 30 minutes and processed through specialized equipment, which micronizes and activates stem cells and growth factors. Coupled with the self-healing power of platelet rich plasma (PRP) from the patients blood, the fat tissue is injected into targeted areas of the vaginal area, according to patient needs. Urinary leakage, prolapse of the bladder walls, and decreased ability to reach sexual arousal are areas of greatest concern to patients at Fusion Medical Spa & Wellness. Of the women treated with the ALMI O-Shot by Dr. Rath, an unprecedented 100% have reported an increase in orgasm during subsequent sexual encounters, with most women also reporting having reached orgasm at least 90% of the time which is always Dr. Raths goal in treating women struggling with sexual dysfunction in his practice!

As the stem cell-rich adipose tissue, PRP and growth factors stimulate collagen, blood vessels and tissue at the site of injection, results are expected to be long term. Additionally, because Dr. Rath injects with both function and aesthetics in mind, patients at Fusion Medical Spa & Wellness can expect the added benefit of an immediate volumizing effect within, as well as outside the delicate vaginal area. This additional volume is also expected to last, as the surrounding tissue regenerates from the stem cell-rich injections. Patients struggling with urinary incontinence have reported a loss of the need to wear panty liners since receiving the ALMI O-Shot by Dr. Rath a freedom for which these women cannot thank him enough!

Once considered taboo topics only discussed with close girlfriends, simple solutions for female sexual problems and incontinence are becoming more widely pursued in doctors offices across the country. Fortunately, now women no longer have to live with the effects of age, childbirth and a socially-accepted norm that reaching orgasm every now and then is sufficient!

Dr. Rath offers this highly innovative approach as one element of a comprehensive medical program designed to achieve whole-body wellness through functional and integrative medicine. More than just a run-of-the-mill med spa, Fusion Medical Spa & Wellness is a concierge medical practice integrating a wide range of medical and aesthetic specialties, including bio-identical hormone replacement therapy, medical weight loss, as well as anti-aging and aesthetic treatment options.

Dr. Stephen A. Rath is a Board Certified Anesthesiologist who focuses on cutting-edge aesthetic, functional, and integrative medicine with a unique focus on sexual health. He is a consulting physician to Allergan for their entire portfolio of injectable rejuvenation treatments, including Botox, Kybella and their newest injectable, Allure. Dr. Rath is a certified trainer for The Vampire Facelift, ALMI and regenerative orthopedics and sports medicine. Unlike most medical spas, Fusion Medical Spa & Wellness offers anesthesia and sedation for all non-surgical procedures, part of Dr. Raths continued commitment to prioritize patient health, well-being and safety.

If you would like more information about Dr. Stephen A. Raths cutting-edge approach to womens sexual health or on the functional and aesthetic medicine offered at Fusion Medical Spa & Wellness, please contact Dr. Rath at 855.257.4SPA (4772) or contact(at)fusionmedicalspa(dot)net. http://fusionmedicalspa.net/

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Dr. Rath's New O-Shot Uses Fat Cells to Shatter the Gender Orgasm Gap & Eliminate Urinary Leakage for Women - PR Web (press release)

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Stem-cell treatment arrives in Kamloops – Merritt Herald

Posted: July 1, 2017 at 6:44 pm

Photo courtesy of Kamloops This Week.

By: Jessica Wallace (Kamloops This Week)

Gail Walsh didnt want to spend the rest of her days waiting.

The 72-year-old retired Peachland woman said she needed surgical procedures on both knees, hip, neck and back, but didnt want to sit on the waiting list. Instead, she researched alternatives and learned about a doctor in Kelowna offering private stem-cell treatment.

The retired teachers aid committed $6,500 with the hopes of checking some items off her list of procedures.

I thought, I can just see the rest of my days, waiting for surgery after surgery, then recuperating in between, Walsh told KTW. It just seemed to me it was worth the money to try.

Helping people on wait lists is among reasons why a longtime Kamloops neurosurgeon recently began offering stem-cell treatment, despite the fact the procedure is not approved by Health Canada.

The expense [of stem-cell treatment], itll never be offered in the public system, so Canada will be behind the rest of the world, Dr. Richard Brownlee told KTW.Lots of people will do medical tourism, theyll go to Mexico or the States or Germany or whatever to get treatment thats not available here. Wait lists are the other thing.People wait for a year to get a MRI, so if they dont have to wait, they can come in and get one in less than a week or two.

The Welcome Back Centre, a private pain-management clinic on Columbia Street, began offering stem-cell treatment three months ago.

Stem cells are prevalent in humans and can be extracted to help treat degenerative, inflammatory or autoimmune conditions, Brownlee said.

Under the right conditions, stem cells can adapt into other cells. Someone with arthritis may have stem cells injected into a joint to create new cartilage, while athletes may treat soft tissue after a muscle tear, he said.

Brownlee noted the medicine is evolving, even being used to slow down symptoms of but not cure amyotrophic lateral sclerosis (ALS/Lou Gehrigs Disease.)

Stem cells are what do the repairing, Brownlee said. So, if youre putting a big number of those locally at the site of where the injury is, it just encourages healing.

Controversy has surrounded embryonic stem-cell harvest from fetuses. Brownlee said it is both unethical and risky, being that young cells have the potential to change into anything, including cancer.

Much like organ transplant, there is also the risk of the body rejecting them. Brownlees office extracts stem cells from the adults who are receiving them.

If youre taking it directly from the person and processing it and putting it right back in, theres no issues with it, he said.

Brownlee said stem-cell treatment is ideal for people who either havent healed adequately or who have developed degenerative changes over time. Ranging from $5,000 to $10,000 per treatment, it is often sought as a last resort.

The centre has treated about a half-dozen knees and hips and is expanding into other treatments.

Nothing has 100 per cent effectiveness, but most of the conditions, about 85 per cent of people get benefit, Brownlee said.

In offering the first treatment of its kind in the city, Brownlee is educating the public and keeping up with new developments. He just got back from a conference in Beverly Hills through the Cell Surgical Network and said he is looking at joining the group to gain access to data from more than 7,000 cases.

Its just new and different and its something that will probably never be offered through the public system, he said.

As for Walsh, seven weeks after her first treatment, she said its too early to determine if the procedure was successful. Relief could take up to nine months.

All I know is so far, theres nothing harmful done, she said.

Future of stem cells

While Dr. Richard Brownlee said stem-cell treatment will likely never be offered publicly, Prime Minister Justin Trudeau last year announced $20 million in funding to the Centre for Commercialization of Regenerative Medicine to help establish a stem-cell therapy development facility in Toronto.

Regenerative medicine is the future and not only is it the future, its a branch of medicine that Canada and the province of Ontario are actually quite good at, Trudeau was quoted at the time in a story in the Globe and Mail about the announcement.

The medical advances and innovations happening right here in Toronto are world class.

Common applications:

Knees: partial to complete ligament tears, osteoarthritis, partial to complete meniscal tears, augmented ACL or PCL reconstruction;

Shoulder: partial to complete rotator cuff tears, labral tears, osteoarthritis;

Foot and ankle: tendon inflammation, osteoarthritis, patron to complete Achilles tendon tear;

Elbow, wrist and hand: partial to complete ligament tears, epicondylitis, osteoarthritis;

Spine: discogenic back pain, facet arthritis, degenerative disc disease;

Hip: osteoarthritis, labral tears, articular cartilage injuries, avascular necrosis.

Did you know?

Stem cells can be injected locally or delivered intravenously.

Gordie Howe underwent stem-cell therapy after having a stroke and responded well. His family said it helped him walk again, improved his speech and helped him gain weight.

Fat contains 100 to 1,000 times more stem cells than bone marrow.

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Stem-cell treatment arrives in Kamloops - Merritt Herald

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The problematics of genetics and the Aryan issue – The Hindu

Posted: July 1, 2017 at 6:43 pm


The Hindu
The problematics of genetics and the Aryan issue
The Hindu
Tony Joseph's article (How genetics is settling the Aryan migration debate, June 17) heavily leans on two recent studies (which I will refer to after their first author: Silva et al. and Reich et al.) but conceals important methodological issues ...

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The problematics of genetics and the Aryan issue - The Hindu

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Autism genetics, explained | Spectrum | Autism Research News – Spectrum

Posted: July 1, 2017 at 6:43 pm

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Researchers have known that genes contribute to autism since the 1970s, when a team found that identical twins often share the condition. Since then, scientists have been racking up potential genetic culprits in autism, a process that DNA-decoding technologies have accelerated in the past decade.

As this work has progressed, scientists have unearthed a variety of types of genetic changes that can underlie autism. The more scientists dig into DNA, the more intricate its contribution to autism seems to be.

Since the first autism twin study in 1977, several teams have compared autism rates in twins and shown that autism is highly heritable. When one identical twin has autism, there is about an 80 percent chance that the other twin has it too. The corresponding rate for fraternal twins is around 40 percent.

However, genetics clearly does not account for all autism risk. Environmental factors also contribute to the condition although researchers disagree on the relative contributions of genes and environment. Some environmental risk factors for autism, such as exposure to a maternal immune response in the womb or complications during birth, may work with genetic factors to produce autism or intensify its features.

Genetics in motion: The secret to understanding autism lies largely in our DNA.

Not really. There are several conditions associated with autism that stem from mutations in a single gene, including fragile X and Rett syndromes. But less than 1 percent of non-syndromic cases of autism stem from mutations in any single gene. So far, at least, there is no such thing as an autism gene meaning that no gene is consistently mutated in every person with autism. There also does not seem to be any gene that causes autism every time it is mutated.

Still, the list of genes implicated in autism is growing. Researchers have tallied 65 genes they consider strongly linked to autism, and more than 200 others that have weaker ties. Many of these genes are important for communication between neurons or control the expression of other genes.

Changes, or mutations, in the DNA of these genes can lead to autism. Some mutations affect a single DNA base pair, or letter. In fact, everyone has thousands of these genetic variants. A variant that is found in 1 percent or more of the population is considered common and is called a single nucleotide polymorphism, or SNP.

Common variants typically have subtle effects and may work together to contribute to autism. Rare variants, which are found in less than 1 percent of people, tend to have stronger effects. Many of the mutations linked to autism so far have been rare. It is significantly more difficult to find common variants for autism risk, although some studies are underway.

Other changes, known as copy number variations (CNVs), show up as deletions or duplications of long stretches of DNA and often include many genes.

But mutations that contribute to autism are probably not all in genes, which make up less than 2 percent of the genome. Researchers are trying to wade into the remaining 98 percent of the genome to look for irregularities associated with autism. So far, these regions are poorly understood.

No. At the molecular level, the effects of mutations may differ, even among SNPs. Mutations can be either harmful or benign, depending on how much they alter the corresponding proteins function. A missense mutation, for example, swaps one amino acid in the protein for another. If the substitution doesnt significantly change the protein, it is likely to be benign. A nonsense mutation, on the other hand, inserts a stop sign within a gene, causing protein production to halt prematurely. The resulting protein is too short and functions poorly, if at all.

Most mutations are inherited from parents, and they can be common or rare. Mutations can also arise spontaneously in an egg or sperm, and so are found only in the child and not in her parents. Researchers can find these rare de novo mutations by comparing the DNA sequences of people who have autism with those of their unaffected family members. Spontaneous mutations that arise after conception are usually mosaic, meaning they affect only some of the cells in the body.

Perhaps. Girls with autism seem to have more mutations than do boys with the condition. And boys with autism sometimes inherit their mutations from unaffected mothers. Together, these results suggest that girls may be somehow resistant to mutations that contribute to autism and need a bigger genetic hit to have the condition.

Clinicians routinely screen the chromosomes of a developing baby to identify large chromosomal abnormalities, including CNVs. There are prenatal genetic tests for some syndromes associated with autism, such as fragile X syndrome. But even if a developing baby has these rare mutations, there is no way to know for sure whether he will later be diagnosed with autism.

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After vote, Accelerated Genetics slated to merge – La Crosse Tribune

Posted: July 1, 2017 at 6:43 pm

Accelerated Genetics and Select Sires Inc. will be a merged cooperative.

According to a news release, the merger follows a June 22 vote by Accelerate Genetics officials. The vote green-lights an agreement recommended by both companies boards of directors. The smaller Accelerated Genetics has reported financial difficulty in the past. The larger Ohio-based Select Sires will acquire Accelerated Genetics assets, including a bull farm in Westby.

Both companies specialize in artificial insemination of cattle. The companies have an established working relationship that started in 2001 when the companies allied in international markets.

Accelerated Genetics has been searching for a partner who could enhance the business and move it forward, said Scott Dahlk, Accelerated Genetics Board chairman. Joining forces with Select Sires is a positive move for both the member-owners and producers worldwide.

The company said Accelerated Genetics assets, employees and sales representatives will be integrated into the organization. Both companies operate under the cooperative-business model and share similar structures, according to the company.

By working together we will be stronger, said David Thorbahn, Select Sires president and chief executive officer. The value and expertise gained by joining the people from both organizations allow us to offer our customers a broader genetics program in addition to an outstanding animal health product line. Its very exciting to work together, enabling our organizations the ability to expand genetic research, technical support, service, and programs with people who are passionate about the dairy and beef industries.

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After vote, Accelerated Genetics slated to merge - La Crosse Tribune

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How culture, passion and genetics are fueling a Nigerian takeover of US sports – CBS sports.com (blog)

Posted: July 1, 2017 at 6:43 pm

It wasn't just coincidence to Bobby Burton. The 47-year-old Houston native had been covering college football recruiting for more than 20 years. With increased frequency, the best players he saw were more Americanized than American.

Burton lives in a Houston recruiting hotbed, but what he increasingly saw created a recruiting quandary. Who were these kids with the strange names? They were polite, dedicated and often studs.

They absolutely were Nigerian, or the second-generation offspring of Nigerians, playing the hell out of American football.

"You're always looking for the next thing in recruiting," said Burton, a writer for 247Sports.

This one hit him between the eyes.

All of it made sense when Burton did the math. Nigeria is the seventh most populous nation in the world (190 million). There are more Nigerian immigrants in the United States (376,000) than anywhere in the world. The Houston metro area is home to most Nigerians in the country (about 150,000).

Somehow their culture, their drive, their family structure and, oh yes, their bodies seemed to fit football.

With some meticulous research, Burton determined that in the 2016 NFL Draft there were as many players taken from Lagos, Nigeria, as from the city of Chicago (three).

"Unbelievable, unbelievable," said Hakeem Olajuwon, the acknowledged pied piper for Nigerian athletes after coming out the University of Houston in 1984 and becoming a member of the Naismith Memorial Basketball Hall of Fame.

"You can see the talents coming out."

It turns out, this phenomenon was bound to happen.

"I think it was kind of that moment in time," Burton said. "It's gone past the point of coincidence It's no longer just [an] anomaly. It's part of the fabric of football and football recruiting in this country."

Their story goes beyond college football -- or even college athletics. Forget any athletic stereotype, Nigerians have a fierce family pride and dogged belief in education -- particularly higher education -- that allows them to succeed in this country.

These noble West African natives and their descendants are the American Dream.

"There is an honor about them," Southern California Trojans coach Clay Helton said.

Helton counts at least five first- or second-generation Nigerians on his roster.

"They're such a regal people," said Chris Plonsky, the women's athletic director at Texas Longhorns .

Oh, and they can play. In the space of four picks at the end of the first round and beginning of the second of that 2016 NFL Draft, three were of Nigerian descent ( Ole Miss Rebels ' Robert Nkemdiche , Texas A&M's Germain Ifedi and Oklahoma State Cowboys 's Emmanuel Ogbah ).

While the NCAA doesn't keep statistics on nationality (only race), Nigerian influence on college sports is obvious. Among the Power Five, only the SEC didn't have at least one player of Nigerian heritage on its all-conference first or second teams in 2016.

The past three seasons, at least one player of Nigerian heritage has finished in the top 25 nationally in tackles.

At least 80 players of Nigerian ancestry have populated professional football, soccer, basketball and even car racing in recent years. In 1987, Christian Okoye ("The Nigerian Nightmare") became the first Nigerian-born NFL player.

Before Okoye, Olajuwon was the inspiration.

"You're totally right," said Emmanuel Acho , a Nigerian-American who played linebacker at Texas and in the NFL. "If you want to start with Hakeem Olajuwon or you want to start with Christian Okoye, [it doesn't matter]."

Hakeem's background in soccer and handball helped his footwork in basketball. Those Phi Slama Jama teams in the mid-1980s changed the game.

But what about the scores of second-generation Nigerians -- those born into a family with at least one Nigerian-born parent? In the 2016 NFL Draft alone, there were three times as many Nigerian players with hereditary ties to the country's dominant tribe -- the Igbo -- (six) than draftees from Florida State Seminoles (two).

Oluwole Betiku might be the next Nigerian phenom in the NFL. The sophomore linebacker is already the talk of Southern California, where they affectionately they call him "Wole" (woe-lay).

Betiku was discovered at a basketball camp in Nigeria. At age 15, he rode 11 hours in a bus to that camp in hopes of finding a better life for his impoverished family.

Desperation doesn't begin to describe it. Seventy percent of the Nigerian population is below the poverty line. Forty percent of the population is illiterate. The AIDS rate there is the highest in the world.

"We have oil everywhere," Sonny Acho said of his native land.

Acho is father of Sam and another Texas/NFL linebacker, Emmanuel. Sonny has become an icon not only in his Dallas community but also for his Nigerian outreach.

"We have a corrupt culture: Get all you can!" he said of Nigeria. "Only a few politicians live large. Millions live in poverty. These are the people that we are trying to go help."

Sam and Emmanuel have been on an estimated 15-20 mission trips back to their parents' homeland. They have recruited friends and teammates to provide basic needs to villages.

"People talk about modern-day miracles," Sam explained. "I saw a lady that was blind, and she received her sight through prayer."

That required some reconfirmation. The mission trip did include some doctors who were removing cataracts. Wasn't that what Sam witnessed?

"She starts praying, praying, praying," Sam said. "The next thing she says is, 'Amen.' I'm standing around the way just kind of seeing what's going on. The lady starts freaking out. They hold up this card and ask her what color it is.

"She says, 'Yellow.'"

A more conventional miracle: Out of that Nigerian camp, Betiku eventually got referred to former Penn State Nittany Lions star LaVar Arrington, who became his legal guardian and brought him to the U.S. Betiku didn't take up football until he was a sophomore at Serra High School in Los Angeles.

At that point, he was so nave to the sport, Wole shed his shoulder pads as an annoyance. Just getting on the field for the Trojans for five games as a freshman was a win.

"I'll never forget him absolutely breaking down into tears one day in our defensive team meeting," Helton said. "They had showed some tape on him and a little bit of praise. He said, 'Coach, if you could imagine where I was a couple of years ago to where I'm sitting right now. I just thank God for this opportunity.'"

If you want to secure one of these talents, you might want to place a call to Lou Ayeni. He is as plugged in to the Nigerian recruiting scene as anyone. Both parents of Iowa State Cyclones 's running backs coach are from Lagos, Nigeria's capital.

Babs and Flora have PhDs. Dad is a statistical engineer. Mom is a biomedical statistician. One sister, Tina, is a nationally noted oncologist who treated the mother of Iowa State coach Matt Campbell.

"She's trying to find a cure for ovarian cancer," Lou said. "My mom makes fun of me. You went to Northwestern Wildcats to coach football? I don't understand it."

That was after playing tailback and safety for the Wildcats under Randy Walker and surviving eight surgeries in his career. That was after his mother all but hand-picked the elite school for her son.

"My mom says, 'You're going to the best academic school you can go to,'" Lou recalled. "I was high school player of the year in Minnesota. I was enamored with Wisconsin Badgers . My first Big Ten visit was Iowa Hawkeyes . They were really intriguing schools to me."

Flora then interjected: Nothing is happening until you visit Northwestern.

"We go through the academic piece. First thing she says is, 'You're coming here,'" Lou said. "Some Nigerian families are like that."

As an Ayeni, Lou did take the road less traveled. He knows those Dallas and Houston hotbeds.

Running back Kene Nwangwu was the state high jump champion out of Dallas, not the kind of player who come to Ames, Iowa. He was offered by every Big 12 school. Iowa State got him.

"It was an easy sell for me," Ayeni said. "His family is very similar to my family -- 4.0 GPA, yes sir, no sir."

Ayeni says he can see Nigerian talent just by watching tape.

"Some of them," he said. "If I hear the name and watch them, I'll know if they're Nigerian."

Their names are often lyrical, peaceful and meant to convey both their faith and future -- Blessing, Sunday, Passionate, Peace, Promise, Princess.

Former Iowa State offensive lineman Oni Omoile was part of a royal bloodline in Nigeria. His nickname on the team quickly became "Prince."

"We know each other by our last names," Sonny Acho said. "You give me somebody's last name, not only will I know that person is from Nigeria, I will even tell you where the person is from. It tells you the tribe and the language the person speaks."

"Acho" means "I have found what I'm looking for," according to Sonny. Burton says he knows Nigerians by another definition.

"I've been doing this a long time," he said. "I can't remember a Nigerian kid ever having grade problems. It's not the physical nature of their ability. It's the maximization of what they have."

There are other cultures that stress education and family. Why are Nigerians different to be the subject of this talent/recruiting boom?

The Immigration and Nationality Act of 1965 was a direct result of the growing civil rights movement. It relaxed immigration quotas. The Refugee Act of 1980 made it easier for African immigrants to come here. That was important for those fleeing conflict-impacted areas, such as Nigeria.

That Nigerian U.S. population of 376,000 is roughly the size of New Orleans. That sample size has produced an athletic revolution.

WNBA players Chiney and Nneke Ogwumike -- from the Houston suburb of Tomball -- were the only other siblings besides the Mannings to be drafted No. 1 overall in a U.S. professional sports league (2012, '14).

They are part of the fabric of a metro area. Half of all African immigrants in Houston are from Nigeria

"Why is there such a concentration in Houston?" asked Stephen Klineberg, a sociology professor at Rice. "It's the classic story of immigration. You go where you know people. You go there because your cousin is there."

And the climate is roughly the same. The humidity and warmth of Houston is similar to Lagos. That gives rise to the some of the first families of Nigerian-American sports -- the Achos, the Orakpos, the Okafors.

All-American linebacker Brian Orakpo came out of Houston to win a national championship at Texas. He has been selected for the Pro Bowl in half of his eight pro seasons.

Emeka Okafor was the first member of his Nigerian family born in the United States. The former UConn basketball star and No. 2 overall draft pick played 10 NBA seasons. Distant cousin Jahlil Okafor was the No. 3 pick overall in 2015 out of Duke.

The Nigerian surge in athletics is best described another way: Half of all Nigerians have arrived in the country since 2000. Twenty-nine percent of those immigrants age 25 or older hold a master's degree. That's compared to 11 percent of the overall U.S. population. Eight percent of those Nigerians hold doctorate degrees compared to 1 percent of the U.S. population. This 2008 story calls them the most educated ethnicity in the U.S.

The NCAA's antiquated bylaws constantly remind us a degree doesn't necessarily equal an education. But in the Nigerian culture, education is the foundation for life.

Sam Acho could have played anywhere. His athletic talent was evident. But he was also being recruited by elite schools including several in the Ivy League. Sonny had to be convinced Texas was worthy of his son.

"Sam got into Texas' McCombs School of Business," Sonny said. "That solved the problem. Mack Brown basically knew we were strong people. Anything outside of that was going to cause a problem. They allowed us to be involved in the boy's lives. It's all about academics first and football second."

In 2010, Sam won the Campbell Trophy, the so-called "Academic Heisman" for the nation's top football scholar-athlete. Sam has a master's in international business. Emmanuel has a master's in psychology.

As kids, they led somewhat of a cloistered life. Such is the influence of parents. Sonny said former USC coach Pete Carroll once pulled Sam from a group of 300 and tried to get him to commit.

So you can sort of understand a natural skepticism.

"My kids couldn't do sleepovers," Sonny said. "I don't know what you have going on in your house. I'm not willing to let my son go over there and something goes wrong and then they accuse my son of raping many African parents will be like that."

A large part of this story is simple math and demographics. Nearly 16 percent of the United States' population has ties to Africa, and nearly five percent of its immigrant population is from Nigeria. The only countries in the world larger than Nigeria are Pakistan, Brazil, Indonesia, the United States, India and China. According to a new United Nations report, Nigeria will be the third-most populous country in the world by 2050, overtaking the United States.

There are more native Nigerians in the U.S. than from any other African nation. In 1980, that number was 25,000. As the refugee laws began to loosen, in every decade from the 1980s through the 2000s, at least 10 million immigrants came to the U.S.

Eighty-eight percent of those were of Asian, Latin American, Caribbean or African descent, Klineberg said.

"It's a new immigration stream that has never existed before in American history," he added.

Nigerian families tend to be large, accomplished and -- as mentioned -- extremely close. Florida State All-ACC defensive tackle Derrick Nnadi says he talks to each of his six siblings daily via social media.

"Every day we have a whole group chat," he said.

A brother, Bradley, is an actor in Southern California. A sister, Ashley, got into the nursing program at Old Dominion. Derrick somehow ended up the kid with his hand in the dirt -- although one with a 3.12 grade-point average last semester.

"I have four jobs," Derrick said. "Go to class, study, get conditioned, play football. That really boils down to two jobs."

You shouldn't even have to ask. Consider his father, Fred Nnadi. He came to the U.S. with his brother decades ago determined to carve out a life as an engineer.

But like a lot of immigrants, he was hindered by his nationality and the language barrier.

"I went to a job interview one time. I had three degrees going in," Fred said. "I applied to be a meter reader. The supervisor doesn't have the degree I have.

"He hired me and didn't say a word. When I left, he started tell me he wished he had the education I had. I had to feed my family. That's why we emphasize education."

But perhaps the only reason Derrick is at Florida State in the first place is that Fred survived the brutal Nigerian civil war from 1967-70.

Up to two million might have died in the bloody conflict. It evolved as Nigeria was finding its identity as an independent nation after separating from the United Kingdom in 1960.

As a teenager, Fred voluntarily joined what he said were the equivalent of U.S. Army Rangers, fighting behind enemy lines. This was in the days of governmental conscription.

"It was a war of genocide It was a terrible war," Fred said. "That war, they have not recovered. I'm not kidding you. I don't care what anybody says."

Those who survived at least had the chance to pass on their genes in the United States. Fred's father had been a tribal chief back in the homeland with "many wives" who "when he walked on land, the ground shook."

"I have so many brothers and sisters," Fred said. "We were in the hundreds. He was a very great man. I have to tell you, when you look at Derrick, he's black and big. You're looking at my father."

That memory of Chief Ezeoha explains some of the why the 6-foot-1, 312-pound Derrick became one of three "Seminole Warriors" on the team by throwing up 525 pounds on the bench.

"I have a video if you want to see it," Derrick said proudly. "I will never shy from showing the video."

After that civil war, a series of oppressive dictators emerged. Lately, the ISIS-affiliated Boko Haram has terrorized Nigerians.

Like all Nigerian athletes spoken to for this story, they seem to be Americans first. Some have been back to the homeland. All of them can't forget it.

"Killing this goat right in front of us and slicing it's neck," USC tight end Daniel Imatorbhebhe said while recalling a visit from his childhood. "[I remember] it running it around. We ate it later in the day. It was spicy."

In one sense, Imatorbhebhe is as American as the corner McDonald's. He was born in Nigeria but grew up in suburban Atlanta before signing with Florida Gators and immediately transferring to USC.

Imatorbhebhe's mother is a biomedical consultant. His father worked for a mortgage company before the financial crash. His brother, Josh, is a Trojans receiver.

"It's tough because it's like we're not really seen as in the some mold as an African-American kid," Daniel said. "Teammates have always said, 'Y'all are just built different. What do you attribute that to? Is it what you eat?'"

Yes, if you consider Nigerian staples oxtail, coconut rice and fufu the diet of champions. The family is also Yoruba, another common tribe in Nigeria.

Read more here:
How culture, passion and genetics are fueling a Nigerian takeover of US sports - CBS sports.com (blog)

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Hampton Creek to enter clean meat market in 2018: ‘We are building a multi-species, multi-product platform’ – FoodNavigator-USA.com

Posted: June 30, 2017 at 12:46 pm

The first commercial product from Hampton Creeks new clean meat production platform will likely be in the avian family, director of cellular agriculture Eitan Fischer told FoodNavigator-USA as the company best known for its work on plant-based proteins unveiled ambitious plans to explore the animal variety.

Fischer was speaking to us after Hampton Creek founder Josh Tetrick posted anarticle on linkedin explaining that producing 'clean' or 'cultured' meat (by culturing cells without raising or slaughtering animals) and plant-based meat/eggs, both stemmed from a desire to find kinder and more sustainable alternatives to industrial animal farming.

His comments came as Dr Eric Schulze, senior scientist at Memphis Meats probably the best-known clean meat company told delegates at the IFT show this week that his company aims to launch premium-priced clean meat products in high-end restaurants in 2019, and more mass market products in grocery stores in 2021.

Poultry will likely be first to market in late 2018, Fischer told us: We believe the first product released commercially will likely be in the avian family.

Longer term, however, the plan is to build a multi-species, multi-product platform spanning the entire range of meat and seafood, he said.

We haven't solved the meat and seafood problem until we are able to make all of these products.

Asked how long Hampton Creek had been working on the technology, and what kinds of scientists were working on the project, he said: We have been working on this for over a year. Many members of our 59-person R&D team are involved, between our molecular team, our analytical chemistry team, our process team, and our product development team.

We also supplemented the significant in-house expertise we had previously with additional, more specific specialists such as scientists with stem cell biology, medicine, and tissue engineering backgrounds.

"We believe that clean meat can be evaluated and regulated within existing regulatory frameworks... Clean meat is a food, not a drug, not a new animal drug or a food additive..." [read more on this at FoodNavigator-USA next week..]

Rebecca Cross, counsel,Davis Wright Tremaine LLP

We think its unlikely that families in Alabama (or anywhere in the world) will consistently choose plant-based alternatives over chicken, beef, pork, and seafood Over the past year, weve started the early work of expanding our platform to solve the technical challenges of scalable clean meat.

With plants providing nutrients for animal cells to grow, we believe we can produce meat and seafood that is over 10x more efficient than the worlds highest volume slaughterhouse.

Imagine choosing between a similarly priced pound of clean high-grade bluefin tuna belly or conventional tilapia from underwater traps. Or clean A5 Kobe beef versus conventional sirloin (corn-fed and confined). Our approach will be transparent and unquestionably safe, free of antibiotics and have a much lower risk of foodborne illness. The right choice will be obvious.

Weve started the process of licensing our discoveries to the worlds largest food manufacturers and, in the years ahead, well do the same with the worlds largest meat and seafood companies.

Josh Tetrick, founder and CEO, Hampton Creek

Fischer would not say what kind of stem cells the company is using, or whether the plan is to first proliferate cells in a stir tank bioreactor and then transfer them to a larger perfusion type bioreactor where they will mature and differentiate in to the different cell types (fat, muscle, connective tissue).

However, he confirmed that, We are building a platform that enables us to produce cells of different types including muscle, fat, and others, in a bioreactor-based process.

As for the go-to-market strategy, he said: We are exploring various options for the initial release but are most focused on how to get the costs down to parity or below current meat prices. We haven't truly solved the meat and seafood problem until we've done so.

The company has not said what it is using as a growth medium (the nutrient-rich bath the cells need to grow) but said its expertise in plant-based products had enabled it to develop a viable vegan alternative to animal serum.

"The entry of a billion-dollar company into the clean meat market sector is a vote of confidence in the technology, and we hope that Hampton Creek will be the first of many major food companies to dive into this incrediblypromisingfield."

Bruce Friedrich, executive director, The Good Food Institute

In a mapping document penned by the Good Food Institute earlier this month, the authors predicted that clean meat would likely come to market in phases, with the first products perhaps hybrids combining clean meat and plant-based meat; followed by ground meat products (nuggets, burgers); and finally those mimicking steaks or chicken breasts, which present significantly greater technical challenges.

The first products that come to market may be hybrid products wherein clean meat is included as a part of plant-based products that essentially require only cell lines, media, and proliferative bioreactors to come to fruition.

They add: The next commercial products will likely be ground meat mimics, where scaffolding can be minimal; more complex structures requiring vascularization or perfusion bioreactors are not necessarily required.

Finally, more structured tissues like those mimicking steaks or chicken breasts will require research and development in all of the areas outlined above. Thus, a consideration of target product(s) should drive the R&D focus.

Speaking at a webinar hosted by the GFI on June 8, Dr Specht added: "I think there's a lot of evidence to suggest that consumers would be interested in hybrid products," citing the success of products already on the market that feature combinations of regular meat and plant-based ingredients, such as mushroom blend burgers and sausages with 40% meat, which are marketing on a health and sustainability platform, and can also be more affordable.

"The phrase 'clean meat' is similar to 'clean energy' in that it immediately communicates important aspects of the technologyboth the environmental benefits and the decrease in food-borne pathogens and drug residues."

Bruce Friedrich, executive director, The Good Food Institute

This Good Food Institute schematic illustrates one conception of the clean meat production process at scale. The first stage is proliferation of the cells, followed by a differentiation and maturation stage where cells are seeded onto scaffolds and allowed to mature into the cell types required for meat.

Clean meat production begins with obtaining cell lines for the desired animal species (eg. chicken, pork, beef) that behave in a predictable way through many generations, while maintaining an unlimited capacity to reproduce/divide (ie. immortalized cell lines).

Next you have to proliferate cells, perhaps in a stir tank bioreactor where you might suspend your cells in the growth medium (both Hampton Creek and Memphis Meats claim to have found viable alternatives to animal serum read more about that HERE ) and stir them and keep them warm.

As for the next stage, where you want to encourage the creation of an organized pattern of muscle, fat, and connective tissue cells, this would probably require seeding onto scaffolding and then differentiating into the various cell types, the stage at which you get real fat cells forming and the muscle cells forming into fibers to give that authentic meaty texture, said Dr Specht.

Here, the scaffolding would need to be something that is subsumed within the final meat product so it would have to be made out of something that is degradable over time, or something edible that would not impact the taste or safety of the final product such as cellulose or collagen, she said.

To accommodate three-dimensional growth, the scaffolds must exhibit porosity for perfusing nutrient media [the nutrients have to be able to reach the cells], she added. Alternatively, they must support vascularization of the tissue itself, i.e., the formation of a network of vessels to allow nutrients to permeate the tissue. Several production methods, including 3D printing and spun-fiber platforms, allow fine-tuning of pore size and microstructures within the scaffold.

"Once you get to the scaffold stage, that area is less explored and has not yet been demonstrated at scale."

Interested in clean meat?

GFI senior scientist Dr Liz Specht will give delegates at FOOD VISION USA 2017 the lowdown on clean meat, while Alex Lorestani will explain how Geltor is producing gelatin without animals. See the latest speaker list HERE .

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Hampton Creek to enter clean meat market in 2018: 'We are building a multi-species, multi-product platform' - FoodNavigator-USA.com

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