Pancreatic cancer is one of the deadliest types of cancer. It is the fourth most common cause of cancer deaths in the United States. More than 43,000 people are diagnosed with pancreatic cancer each year and about the same number die each year from the disease. Only about 3% of people with pancreatic cancer live more than five years after diagnosis.
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There are several reasons why this type of cancer is so lethal
Scientists at the U-M Comprehensive Cancer Center are studying pancreatic cancer in an effort to find new and more effective treatments for patients with this deadly disease. In 2007, Cancer Center scientists were the first to identify a small group of cells, called cancer stem cells, in tumors from patients with pancreatic cancer. Researchers believe these stem cells are the key to finding an effective treatment and possibly someday a cure for pancreatic cancer.
U-M research shows that just a few cancer stem cells are responsible for the growth and spread of pancreatic cancer. Unless these stem cells are destroyed, the cancer will return. The goal of U-M scientists is to develop a new therapy targeted directly at cancer stem cells. If successful, it will be a major step forward in the treatment of pancreatic cancer.
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Since pancreatic cancer is resistant to chemotherapy and radiation, new treatments are needed that can kill the small number of cancer stem cells within the tumor. Studying pancreatic cancer stem cells will help researchers identify targets for new drugs or therapies, which can then be tested in animals and eventually in human clinical trials.
For more information about clinical trials, please contact our Cancer Answerline at 800-865-1125.
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