The 3D Cell Culture Market is expected to reach a value of USD 3721.86 Million by 2027, at a CAGR of 13.4% (2021 2027) – Digital Journal

The increasing focus on discovering alternatives to animal testing, the expanding focus on customized therapy, the rising incidence of chronic diseases, and the availability of research funding are all driving 3D cell culture market forward. However, over the projection period, the absence of infrastructure for 3D cell-based research and the high cost of cell biology research are projected to limit the markets growth.Testing on animals has been the most common technique in various experimental trial studies in biomedical research because they resemble humans in terms of genetics, anatomy, and physiology. Mice genome structure Is 80% similar to humans, which makes them excellent replicas for various research works. On the other hand, the use of animals in scientific research is associated with several ethical concerns, which led to the formation of the code of 3Rs- Reduction, Replacement, and Refinement, to address the moral concerns related to animal wellbeing and limit the use of animals in scientific research.

As of 2018, this initiative led to a 50% decrease in the use of animals as compared to the statistics from 1985. Additionally, the practice of animal breeding housing for scientific purposes is also associated with high costs and needs skilled labor. Furthermore, it has been confirmed that animal cell cultures are unable to precisely mimic the natural (in vivo) microenvironment as the cells cultured in monolayers are both morphologically and physiochemical different from their in vivo counterparts. These concerns have demanded a transition from animal testing to the use of 3D cell culture models. Over time the advancement in biotechnology and materials science has enabled the development of a variety of 3D cell culture systems to determine the research across different areas, including cancer research, drug discovery, tissue engineering, and others.

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More than 140 companies offer 3D cell culture systems at present in a variety of formats, which includes scaffold-based products, scaffold-free products, and 3D bioreactors. These systems have been confirmed to be capable of more precisely simulating the natural tissue microenvironment, offering increased cell to cell and cell to ECM connections, more precise evaluation of drug toxicity and cellular responses, and culturing multiple cell types together. Furthermore, there are definite complex 3D cell culture models that can even replace animal models demonstrating reproducible results and thus, serving as better in-vivo models across multiple applications. Given the various benefits of such systems, the field has gathered the attention of various VC firms and strategic investors that have been providing monetary support to drive research efforts focused on exploring different formats of 3D cell culture systems, including organoids and organ on chips across multiple use case. Additionally, there has been an increase in the scientific works on 3D cell culture systems and partnerships for 3D bioreactors and cell culture products. Given the current innovation in this field and the pattern shift from 2D cell culture systems and animal testing to 3D cell culture models, the market is likely to witness significant growth in the predicted future.

The North American region accounted for the highest revenue share of over 43% and led the global 3D cell culture market in 2020. The region will hold its leading position throughout the forecast period. The availability of private and government funding for the innovation of advanced 3D cell culture models accounts for this growth in the region. High healthcare spending and the presence of numerous universities and research organizations investigating various stem cell-based methods push the growth in the sector. Researchers from Mayo Clinic and Terasaki Institute in the US developed visible hydrogels that can be used for the monitoring and control of hemorrhage, in December 2020. Asia Pacific is likely to grow at the fastest CAGR in the global 3D cell culture market and is likely to continue the same trend during the forecast period. This is attainable due to growing investments by several companies and rising healthcare spending in developing economies like China and India in the region. Also, government support & planned initiatives are expected to support the growth of the market in near future.Read the market research report, The Global 3D cell culture Market is segmented By Product (Scaffold-Based 3D cell culture, Scaffold-Free 3D cell culture, Microfluidics, and 3D Bioreactors), By Application (Drug Discovery, Tissue Engineering, Cancer Treatment, Regenerative medicine, Clinical, and Other Applications), By End User (Research Laboratories and Institutes, Biotechnology and Pharmaceutical Companies and Academic Institutes) & By Region- Forecast and Analysis 2021-2027. by SkyQuest

As a result of the domains technological nascence, no company currently wields significant influence, and the race to dominance has already begun, with companies investing in multiple 3D Cell Culture projects, acquiring a few on their way to the finish line in the domain. The top players in this market include 3D Biotek LLC (US), Advanced Biomatrix Inc. (US), Avantor Inc. (US), Becton, Dickinson, and Company (US), Corning Incorporated (US), Lonza Group (Switzerland), InSphero AG (Switzerland), Merck & Co., Inc (US), Synthecon Inc. (US), Thermo Fisher Scientific Inc. (US).

The report published by SkyQuest Technology Consulting provides in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions.

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SkyQuest has segmented the Global 3D Cell Culture Market based on Product, Application, End-User, and Region: 3D Cell Culture Product Outlook (Revenue, USD Million, 2021 2027)o Scaffold-Based 3D cell cultureo Scaffold-Free 3D cell cultureo Microfluidicso 3D Bioreactors 3D Cell Culture Application Outlook (Revenue, USD Million, 2021 2027)o Drug Discoveryo Tissue Engineeringo Cancer Treatmento Regenerative medicineo Clinical, and Other Applications 3D Cell Culture End-User Outlook (Revenue, USD Million, 2021 2027)o Research Laboratories and Instituteso Biotechnology and Pharmaceutical Companieso Academic Institutes 3D Cell Culture Regional Outlook (Revenue, USD Million, 2021 2027)o North America U.S. Canadao Europe Germany France UK Italy Spain Rest of Europeo Asia Pacific China India Japan Rest of Asia Pacifico Central & South America Brazil Rest of CSAo Middle East & Africa GCC Countries South Africa Rest of MEA

List of Key Players of the 3D Cell Culture Market 3D Biotek LLC (US) Advanced Biomatrix Inc. (US) Avantor Inc. (US) Becton, Dickinson, and Company (US) Corning Incorporated (US) Lonza Group (Switzerland) InSphero AG (Switzerland) Merck & Co., Inc (US) Synthecon Inc. (US) Thermo Fisher Scientific Inc. (US)

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The 3D Cell Culture Market is expected to reach a value of USD 3721.86 Million by 2027, at a CAGR of 13.4% (2021 2027) - Digital Journal