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Category Archives: Missouri Stem Cells

Brain’s stem cells slow ageing in mice – Nature.com

Posted: July 30, 2017 at 9:43 pm

Patrick Landmann/SPL

Mice aged more slowly when injected with stem cells from the brains of newborns.

Stem cells in the brain could be the key to extending life and slowing ageing. These cells which are located in the hypothalamus, a region that produces hormones and other signalling molecules can reinvigorate declining brain function and muscle strength in middle-aged mice, according to a study published on 26 July in Nature1.

Shamini Bundell discovers more about the brains role in ageing

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Previous studies have suggested that the hypothalamus is involved in ageing, but the latest research shows that stem cells in this region can slow the process. That makes sense, because the hypothalamus is involved in many bodily functions, including inflammation and appetite, says Dongsheng Cai, a neuroendocrinologist at Albert Einstein College of Medicine in New York City.

In their study, Cai and his colleagues found that stem cells in the hypothalamus disappear as mice grow older. When the researchers injected their mice with viruses that destroy these cells, the animals seemed to grow older faster, experiencing declines in memory, muscle strength, endurance and coordination. They also died sooner than untreated mice of the same age.

Next, the team injected stem cells taken from the hypothalami of newborn mice into the brains of middle-aged mice. After four months, these animals had better cognitive and muscular function than untreated mice of the same age. They also lived about 10% longer, on average.

The researchers found that these stem cells release molecules called microRNAs, which help to regulate gene expression, into the cerebrospinal fluid. When the team injected these microRNAs into the brains of middle-aged mice, they found that the molecules slowed cognitive decline and muscle degeneration.

It's an interesting paper, says Leonard Guarente, a molecular biologist at the Massachusetts Institute of Technology in Cambridge, who studies ageing. He adds that it could lead to various ways of developing anti-ageing therapies in people.

Stem-cell therapies might enhance the ability of the hypothalamus to act as a master regulator, given that the latest results suggest it controls ageing through signalling peptides such as hormones and microRNAs, Cai says. He says that his team is trying to identify which of the thousands of types of microRNA produced are involved in ageing, and hopes to investigate whether similar mechanisms exist in non-human primates.

The findings represent a breakthrough in ageing research, says Shin-ichiro Imai, who studies ageing at Washington University in St Louis, Missouri. The next steps would be to link these stem cells with other physiological mechanisms of ageing, he says. For instance, these cells may have a role in regulating the neurons that release a hormone called GnRH, which is secreted by the hypothalamus and is associated with ageing. Imai would also like to know whether the microRNAs from the cells can pass into the bloodstream, which would carry them throughout the body.

Cai suspects that anti-ageing therapies targeting the hypothalamus would need to be administered in middle age, before a persons muscles and metabolism have degenerated beyond a point that could be reversed.

It is unclear by how much such a therapy could extend a human lifespan, but Guarente says that slowing the effects of ageing is the more important goal. Living longer isnt important if youre not healthy, he says.

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Chemical persuasion by David Sparks Ph.d, click here for bio – AgInfo.net (press release) (registration) (blog)

Posted: July 30, 2017 at 9:43 pm

When it comes to nematodes, unraveling the root of the issue is complicated. These tiny parasites siphon off the nutrients from the roots of important crops like soybeans, and scientists keep uncovering more about how they accomplish this task. Research from the University of Missouri lab of Dr. Melissa Mitchum recently pinpointed a new way nematodes take over root cells.

In a normal plant, the plant sends different chemical signals to form different types of structures for a plant. One of those structures is the xylem for nutrient flow, Plant researchers discovered a peptide signal for vascular stem cells several years ago, but this is the first time anyone has proven that a nematode is also secreting chemical mimics to keep these stem cells from changing into the plant structures they normally would.

Stem cells? Xylem? Chemical mimics? Lets unpack whats going on.

First, all plants contain stem cells. These are cells with unbridled potential and are at the growth centers in a plant. Think the tips of shoots and roots. With the right urging, plant stem cells can turn into many different types of cells.

That influence often comes in the form of chemicals. These chemicals are typically made inside the plant and when stem cells are exposed to them at the right time, they turn certain genes either on or off that in turn start a transformation of these cells into more specialized organs.

Want a leaf? Expose a stem cell to a particular combination of chemicals. Need a root? Flood it with a different concoction of peptides. The xylem the dead cells that pipe water and nutrients up and down the plant requires a particular type of peptide that connects with just the right receptor to start the process.

But for a nematode, the plan is to hijack the plants plan and make plant cells feed it. This microscopic worm attaches itself to a root and uses a needle-like mouthpiece to inject spit into a single root cell. That spit contains chemical signals of its own engineered to look like plant signals. In this case, these chemicals B-type CLE peptides and their purpose are just being discovered by Mitchums lab.

Now a nematode doesnt want to turn its feeding site into xylem because these are dead cells it cant use, so they may be tapping into part of the pathway required to maintain the stems cells while suppressing xylem differentiation to form a structure that serves as a nutrient sink, Mitchum said. To me thats really cool.

This means these cells are free to serve the nematode. Many of their cell walls dissolve to create a large nutrient storage container for the nematode and some create finger-like cell wall ingrowths that increase the take up of food being piped through the roots. For a nematode, thats a lifetime of meals for it while it sits immobile, just eating.

But how did scientists figure out and test that this nematodes chemical was the cause?

Using next generation sequencing technologies that were previously unavailable, Michael Gardner, a graduate research assistant, and Jianying Wang, a senior research associate in Mitchums lab, compared the pieces of the plant and nematode genome and found nearly identical peptides in both B-type CLE peptides.

Everything is faster, more sensitive and we can detect things that had gone undetected through these technological advances that didnt exist 10 years ago, Mitchum said.

To test their theory, Xiaoli Guo, postdoctoral researcher and first author of the study in Mitchums lab synthesized the B-type CLE nematode peptide and applied it to vascular stem cells of the model plant Arabidopsis. They found that the nematode peptides triggered a growth response in much the same way as the plants own peptides affected development. They used mutant Arabidopsis plants engineered to not be affected as much by this peptide to confirm their findings. We knocked out genes in the plant to turn off this pathway, and that caused the nematodes feeding cell to be compromised. Thats why you see reduced development of the nematode on the plants.

This all matters because these tiny nematodes cost U.S. farmers billions every year in lost yields from soybeans, and similar nematodes affect sugar beets, potatoes, corn and other crops. While this discovery is just a piece of a puzzle, these pieces hopefully will come together to build better crops. You have to know what is happening before you can intervene, Mitchum said. Now our biggest hurdle is to figure out how to not compromise plant growth while blocking only the nematodes version of this peptide.

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Chemical persuasion by David Sparks Ph.d, click here for bio - AgInfo.net (press release) (registration) (blog)

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Pig research could improve IVF in humans – Wallace’s Farmer

Posted: July 30, 2017 at 9:43 pm

Researchers at the University of Missouri have made a discovery that could decrease the costs associated with IVF in humans and it all started with piglets.

The laboratories of Dr. Michael Roberts and Dr. Randall Prather, both University of Missouri Curators' Professors, work with pigs to research stem cells. During an attempt to improve how they grew these cells, researchers stumbled across a method to improve the success of IVF in pigs.

Their discovery doubles the number of piglets born and speeds up the entire IVF process by 400%, which significantly increases both the efficiency of experiments and their potential application to other species. The journal Proceedings of the National Academy of Sciences published their work July 3 in itsonline early edition.

"It was a serendipitous discovery, really," Roberts says. "Generally, there are multiple steps to producing viable embryos that we can then implant in pigs and cows involved in our research; however, it's costly and sometimes yields very little return. We were seeking a way to do that more efficiently and stumbled upon a method that may have implications in human fertility clinics as well."

Increasing eggsIn IVF involving pigs, scientists first extract oocytes (eggs) from female pigs, as well as the "nurse" cells that surround them, and place them in a chemical environment designed to mature the eggs. The eggs are then fertilized to create zygotes, or single-celled embryos that are allowed to develop for six days. These embryos are then transferred back into a female pig with the hope of achieving a successful pregnancy and healthy piglets.

The chance of generating a successful piglet after all those steps is very low; generally, less than 2% of the original oocytes make it that far, Roberts says. "Normally, researchers overcome this low success rate by implanting large numbers of embryos, but that takes a lot of time and money."

Ye Yuan, a former research assistant professor in Roberts' lab, and Lee Spate, a senior research specialist in animal sciences, were tasked with increasing the efficiency and quality of piglet embryos before they are implanted.

It took 3In one study, the team analyzed various special growth factors used when culturing pig stem cells and added two factors fibroblast growth factor 2 (FGF2) and leukemia inhibitory factor (LIF). They found that this combination, when added with a third factor insulin-like growth factor created the special fluid environment the oocytes needed to become competent for fertilization, and further development to embryos, that could provide a successful pregnancy.

Together, the three compounds create the chemical medium called "FLI," which could revolutionize both piglet and human IVF treatments; a patent application has been filed through the MU Office of Technology Management and Industry Relations to encourage commercialization of the new method.

"It improved every aspect of the whole process and almost doubled the efficiency of oocyte maturation," Roberts says. "Whenever you're doing science, you'd like to think you're doing something that could be useful. When we started it wasn't to improve fertility IVF in women, it was to just get better oocytes in pigs. Now it's possible that FLI medium could become important in bovine embryo work, and possibly even help with human IVF."

Source: University of Missouri, Columbia

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Neuralstem, Inc. (CUR) Just Recorded A Sigfniciant Increase – Weekly Register

Posted: July 9, 2017 at 3:45 pm

July 6, 2017 - By Vivian Park

Investors sentiment decreased to 0.3 in Q4 2016. Its down 0.37, from 0.67 in 2016Q3. It worsened, as 16 investors sold Neuralstem, Inc. shares while 11 reduced holdings. 2 funds opened positions while 6 raised stakes. 6.88 million shares or 44.05% less from 12.30 million shares in 2016Q3 were reported. Guggenheim Cap Limited Liability has 51,217 shares. Vanguard Gp has 0% invested in Neuralstem, Inc. (NASDAQ:CUR) for 3.09 million shares. 120,000 are owned by Fifth Third Retail Bank. Moreover, Pnc Svcs Gp Inc has 0% invested in Neuralstem, Inc. (NASDAQ:CUR). Geode Cap Mgmt Limited Liability owns 1.03M shares for 0% of their portfolio. Natl Asset Management Inc has invested 0.01% of its portfolio in Neuralstem, Inc. (NASDAQ:CUR). Blackrock Institutional Trust Na invested 0% of its portfolio in Neuralstem, Inc. (NASDAQ:CUR). Goldman Sachs Gru Incorporated accumulated 10,440 shares or 0% of the stock. Blair William & Com Il has 0% invested in Neuralstem, Inc. (NASDAQ:CUR) for 418,942 shares. Commonwealth Equity Service reported 0% in Neuralstem, Inc. (NASDAQ:CUR). Gp One Trading Limited Partnership reported 0% in Neuralstem, Inc. (NASDAQ:CUR). First Heartland Consultants, a Missouri-based fund reported 10,000 shares. Bancorp Of Mellon holds 0% or 91,969 shares in its portfolio. Moreover, Kcg has 0% invested in Neuralstem, Inc. (NASDAQ:CUR) for 106,830 shares. 73,775 are held by Wells Fargo Mn.

Since January 25, 2017, it had 4 buys, and 0 insider sales for $80,004 activity. Daly Richard J had bought 2,841 shares worth $10,000. $30,003 worth of Neuralstem, Inc. (NASDAQ:CUR) was bought by LLOYD JONES JONATHAN BRIAN on Friday, March 24.

The stock of Neuralstem, Inc. (NASDAQ:CUR) is a huge mover today! About 67,496 shares traded. Neuralstem, Inc. (NASDAQ:CUR) has risen 3.35% since July 6, 2016 and is uptrending. It has underperformed by 13.35% the S&P500. The move comes after 5 months positive chart setup for the $63.76 million company. It was reported on Jul, 6 by Barchart.com. We have $6.08 PT which if reached, will make NASDAQ:CUR worth $5.74M more.

More notable recent Neuralstem, Inc. (NASDAQ:CUR) news were published by: Bizjournals.com which released: Neuralstem raises $20 million in funding from China-based pharmaceutical company on December 13, 2016, also Prnewswire.com with their article: Neuralstem Appoints Richard Daly as President and Chief Executive Officer published on February 16, 2016, Globenewswire.com published: Neuralstem Announces Publication of NSI-566 Data in a Rodent Model of on March 09, 2017. More interesting news about Neuralstem, Inc. (NASDAQ:CUR) were released by: Globenewswire.com and their article: Neuralstem to Present at BIO CEO & Investor Conference published on February 13, 2017 as well as Globenewswire.coms news article titled: Neuralstem Announces a 1-for-13 Reverse Stock Split with publication date: January 06, 2017.

Neuralstem, Inc. is a clinical-stage biopharmaceutical company. The company has market cap of $63.76 million. The Firm is engaged in research, development and commercialization of central nervous system therapies based on its human neuronal stem cells and its stem-cell derived small molecule compounds. It currently has negative earnings. The Firm has approximately three assets: its NSI-189 small molecule program, its NSI-566 stem cell therapy program and its chemical entity screening platform.

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stem cells – decodingscience.missouri.edu

Posted: December 1, 2016 at 11:45 pm

Scientists use placental cells in lab to study virusBy Phillip Sitter | MU Bond Life Sciences Center

Megan Sheridan, an MU grad student, removes the base solution from a demonstrated sample of stem cells that will be grown into placental cells for study of Zika virus. Within four days of exposure to the correct hormones, the stem cells express genes of placental cells, and within another day start producing placental hormones. The cells are infected with Zika at day four to ensure maximum measurable interaction, as the stem cells naturally die in culture after about ten days. | photo by Phillip Sitter, Bond LSC

Scientists believe they have a better way to study how Zika virus can spread from a pregnant mother to her fetus and their technique doesnt even involve observations of babies in the womb or post-natal examinations.

As soon as we heard about Zika, everybodys light bulbs turned on, said Megan Sheridan, a graduate student at the University of Missouri Bond Life Sciences Center.

Sheridan works in the lab of Toshihiko Ezashi at Bond LSC, and she, in turn, is part of a cross-campus team researching Zika with R. Michael Roberts, Alexander Franz, Danny Schust and Ezashi.

Roberts lab studies pluripotent stem cells progenitor cells which can develop into any other type of cell in the body.

We use the proper signals to drive stem cells to become like placental cells, Sheridan explained. With this capability to stimulate stem cells with growth hormones and inhibitors at opportune moments, Roberts researchers realized they could create enough placental cells to create an environment similar to that of a womb in very early stages of pregnancy.

Megan Sheridan sits in front of a demonstration of her work with pluripotent stem cells. Sheridan is a graduate student who works in Toshihiko Ezashis lab, where she produces cells with placental characteristics from the stem cells in order to study placenta interaction with Zika virus. | photo by Phillip Sitter, Bond LSC

This is something which Sheridan thinks hasnt been done before in regards to studying placental interaction with Zika. Their technique could give a look into the first trimester, when epidemiological studies say a fetus is most susceptible to infection.

Roberts lab is trying to understand the placental barriers vulnerability to Zika virus in its early stage of pregnancy. During this time, an infection could occur even before the mother is aware she is pregnant.

If the lab uses their technique to understand how Zika virus enters placental cells, then potentially they could also learn how to strengthen the placenta as a barrier to Zika and make it a first line of defense against infection of the fetus in the womb. If developing babies dont get infected with Zika, then they wont suffer the consequences of birth defects.

One such defect is microcephaly where a baby is born with a smaller than expected head, which may in turn be a sign that their brain has not fully developed. While infection with Zika virus is rarely fatal or otherwise severe in itself many people dont even develop symptoms birth defects like microcephaly could cause further developmental problems like delays in learning how to speak and walk, intellectual disabilities, difficulty swallowing and problems with hearing and vision, according to global health organizations.

Microcephaly only became a widely documented effect of Zika after a particular strain surged across South and Central America with the infected mosquitoes that carry it, Sheridan explained, but this may be in part because previous Zika infections and outbreaks were themselves poorly documented.

While birth defects caused by Zika have drawn much media attention as the disease has spread northward through our hemisphere from Brazil, studies focusing on infection in the womb have only used placental material that has come to term. This may not be the most accurate way to see how the placenta gets infected in the first place early in pregnancy.

The pathway of Zika virus infection in lab mice isnt really comparable to human infection, because mice arent infected with this virus naturally. Only lab mice that have had their genomes altered to be able to acquire the virus have susceptibility to the infection that can be modeled.

Roberts lab is currently working with the African strain of Zika and obtained strains from Southeast Asia and Central America recently. Theres about a 99 percent genetic similarity across strains, Sheridan said.

Zika virus was first discovered in Africa in Uganda in 1947, according to the Centers for Disease Control and Prevention. The first human case was documented in 1952, and subsequent outbreaks also occurred in Southeast Asia and the Pacific Islands. The Pan American Health Organization issued an alert about the confirmed arrival of the virus in Brazil in May 2015.

The lab has completed Zika infections of some of their stem cell-produced placental cells. Sheridan reassured that even though the lab works with live viruses, Zika is not airborne, and none of their work involves mosquitoes.

Roberts lab submitted one grant application earlier this year to the National Institutes of Health for funding for their research. While that application was denied, Sheridan said that they have a lot more preliminary data now and are hoping to submit a revised grant soon.

She said that their original work was highly scored, but the funding level is still low, meaning that obtaining funds for research into Zika virus is highly competitive nationally.

Legislation to fund more efforts into studying and preventing transmission of Zika virus is caught in congressional gridlock, according to The New York Times and other media outlets.

In the mean time, as the Roberts lab prepares its next grant application submission, Sheridan said of her efforts that she is working hard to make progress on the project as quickly as possible.

Please visit the CDCs dedicated page for more information on Zika virus including advice for travellers and pregnant women, description of symptoms and treatment, steps you can take to control mosquitoes and prevent other means of transmission of the virus and more background on the history and effects of the disease.

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Stem cells can repair torn tendons or ligaments …

Posted: October 6, 2016 at 7:46 am

Weekend athletes who overexert themselves running or playing basketball may one day reap the benefits of research at the Hebrew University of Jerusalem that shows that adult stem cells can be used to make new tendon or ligament tissue.

Tendon and ligament injuries present a major clinical challenge to orthopedic medicine. In the United States, at least 200,000 patients undergo tendon or ligament repair each year. Moreover, the intervertebral disc, which is composed in part of tendon-like tissue, tends to degenerate with age, leading to the very common phenomenon of low-back pain affecting a major part of the population.

Until the present time, therapeutic options used to repair torn ligaments and tendons have consisted of tissue grafting and synthetic prostheses, but as yet, none of these alternatives has provided a successful long-term solution.

A novel approach for tendon regeneration is reported in the April issue of the Journal of Clinical Investigation. Researchers Prof. Dan Gazit and colleagues at the Skeletal Biotechnology Laboratory at the Hebrew University Faculty of Dental Medicine engineered mesenchymal stem cells (MSCs), which reside in the bone marrow and fat tissues, to express a protein called Smad8 and another called BMP2.

When the researchers implanted these cells into torn Achilles tendons of rats they found that the cells not only survived the implantation process, but also were recruited to the site of the injury and were able to repair the tendon. The cells changed their appearance to look more like tendon cells (tenocytes), and significantly increased production of collagen, a protein critical for creating strong yet flexible tendons and ligaments.

Tendon tissue repair was detected using a special type of imaging known as proton DQF MRI, developed by Prof. Gil Navon at Tel Aviv University, which recognizes differences among collagen-containing tissue such as tendon, bone, skin, and muscle. The authors note that BMP and Smad proteins are involved in other tissues such as nerve and liver, suggesting that this type of delivery technology may be helpful for other degenerative diseases.

In an accompanying commentary in the Journal of Clinical Investigation, Dwight A. Towler and Richard Gelberman from the Washington University School of Medicine in St. Louis, Missouri, state, "Given our limited understanding of how MSCs become tenocytes, the recent progress demonstrated in these studies is quite remarkable and may be potentially useful in cell-based therapeutic approaches to musculoskeletal injuries."

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The study was supported by GENOSTEM, an integrated project of the European Union for the engineering of mesenchymal stem cells in connective tissue disorders.

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.

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Stem Cells for Orthopedics Missouri & Florida

Posted: September 18, 2016 at 2:48 pm

Orthopedic injuries can happen to anyone. No matter how old you are or how active your lifestyle is, getting hurt will quickly sideline you. As you age, you become even more vulnerable to arthritis and fractures. It is important to keep yourself strong and healthy, and if you get hurt, seek medical attention from a qualified orthopedic doctor as soon as possible.

Blue Tail Medical Group uses innovative methods for treating orthopedic conditions and injuries using regenerative therapies with stem cellsand platelet-rich plasma.

For many patients, stem cell therapy can reduce or eliminate the need for surgery and accelerate the healing process. Stem cell therapy can also provide long-lasting pain relief. Conditions treated range from basic sprains and strainsto degenerative arthritisand back pain.

From head to toe, some common orthopedic conditions we treat with stem cells include:

Visit our patient education libraryto learn more about these conditions.

In addition to stem cells, blood platelets (PRP) can also be administered in a super concentrated injection to stimulate the bodys natural healing process. The regenerative healing power of these therapies is why they are collectively referred to as regenerative medicine.

Using stem cells for orthopedics is a relatively new concept. Many physicians lack the necessary training and experience to offer this cutting-edge therapy to their patients.

Patients from across the US seek treatment at Blue Tail Medical Group. As experts in regenerative medicineour Missouri-based orthopedic doctors have trained other doctors on stem cell therapy procedures. Our doctors also present at conferences all over the world, and in the United States on a monthly basis, earning national recognition as leaders in orthopedic regenerative medicine.

Learn more:

Blue Tail Medical Groupis proud to offer this revolutionary technology for anyone who believes stem cell therapy can help them. Our treatment centersare located in St. Louis and Columbia, Missouri, and Naples, Florida.

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Stem Cells Quotes – Notable Quotes

Posted: September 18, 2016 at 12:48 am

quotations about stem cell research

While we must devote enormous energy to conquering disease, it is equally important that we pay attention to the moral concerns raised by the new frontier of human embryo stem cell research. Even the most noble ends do not justify any means.

GEORGE W. BUSH, speech, August 9, 2001

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In the beginning there is the stem cell; it is the origin of an organism's life. It is a single cell that can give rise to progeny that differentiate into any of the specialized cells of embryonic or adult tissues.

STEWART SELL, Stem Cells Handbook

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The best that can be said about embryonic stem cell research is that it is scientific exploration into the potential benefits of killing human beings.

TOM DELAY, Washington Post, May 25, 2005

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My entire political career, I voted pro-life, and that is exactly why I favor the stem cell initiative. I believe in saving human life. I want cures to be found.

JOHN DANFORTH, TV add sponsored by the Missouri Coalition for Lifesaving Cures, November 2005

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Embryonic stem cell research is at the leading edge of a series of moral hazards.

GEORGE W. BUSH, Address to the Nation on Stem Cell Research, August 9, 2001

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Researchers and biotech executives foresee the day when the effects of many catastrophic diseases can be reversed. The damaged brains of Alzheimer's disease patients may be restored. Severed spinal cords may be rejoined. Damaged organs may be rebuilt. Stem cells provide hope that this dream will become a reality.

GEORGE WOLFF, The Biotech Investor's Bible

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And now science has presented us with a hope called stem cell research, which may provide our scientists with many answers that have for so long been beyond our grasp. I don't see how we can turn our backs on this. There are so many diseases that can be cured or at least helped. We've lost so much time already. I can't bear to lose any more.

NANCY REAGAN, speech at Juvenile Diabetes Research Foundation event, May 8, 2004

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Ethical judgments about the use of embryonic stem cells in research and therapies flow from the status accorded to the embryo. Those who feel that an embryo is a human being, or should be treated as one because it has the potential to become a person, contend that it is unethical to do anything to an embryo that could not be done to a person. At the opposite end of the spectrum, some people have expressed the view that the embryo is nothing more than a ball of cells that can be treated in a manner similar to tissues used in transplantation.

STEVE USDIN, introduction, Human Embryonic Stem Cells

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I think we can do ethically guided embryonic stem cell research. We have 100,000 to 200,000 embryos that are frozen in nitrogen today from fertility clinics. These weren't taken from abortion or something like that. They're from a fertility clinic, and they're either going to be destroyed or left frozen. And I believe if we have the option, which scientists tell us we do, of curing Parkinson's, curing diabetes, curing, you know, some kind of a ... you know, paraplegic or quadriplegic or, you know, a spinal cord injury -- anything -- that's the nature of the human spirit. I think it is respecting life to reach for that cure.

JOHN KERRY, presidential debate, October 8, 2004

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Nuclear transfer technology, which allows you to create stem cells that are genetically identical to a particular patient, may be ... necessary in order to get the full value out of embryonic stem cells. This is the matter of taking the nucleus from a skin cell, putting it in a hollowed-out egg cell in a dish and growing it to the point where you can take stem cells out of it. It never enters a womb. Sperm and egg never meet. There's no pregnancy and yet the opponents of this research continue to cast this in terms of these are little tiny lives. In fact, these are specks smaller than a grain of sand in which we can derive stem cells that could have vast scientific and medical benefit.

DANIEL PERRY, PBS Online NewsHour, October 11, 2004

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I am pro-life. I believe human life begins at conception. I also believe that embryonic stem cell research should be encouraged and supported.

BILL FRIST, speech, July 29, 2005

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As you know, Ronnie recently celebrated his ninetieth birthday. In earlier times, we would have been able to share our mutual pride in a life filled with wonderful memories. Now, while I can draw strength from these memories, I do it alone as Ronnie struggles in a world unknown to me or the scientists who devote their lives to Alzheimer's research. Because of this, I am determined to do what I can to save others from this pain and anguish. I'm writing, therefore, to ask your help in supporting what appears to be the most promising path to a cure -- stem cell research.

NANCY REAGAN, letter to George W. Bush, April 11, 2001

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Stem cells are like toenail clippings with a better career plan.

SCOTT ADAMS, Stick to Drawing Comics, Monkey Brain!

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My point is, and our point as a community, is we have a very good and supportable conclusion that a vast majority of people in this country are in favor of science playing a leading role in making changes in the future and believe in embryonic stem cell research. So we're just saying, know that we have prayed on it, too, and we have thought about it, and we are good people, and we are family people, and we are people that take this very seriously, and we're as concerned as you are. And we've decided that we would like to take this step and to do it with caution and to do it with oversight and to do it with the strictest adherence to ethics and all of the principles this country stands for. But, allow us to do that without infusing the conversation with inflammatory rhetoric and name-calling and fear-mongering. It doesn't help.

MICHAEL J. FOX, ABC interview, October 29, 2006

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At this moment, the full promise of stem cell research remains unknown, and it should not be overstated. But scientists believe these tiny cells may have the potential to help us understand, and possibly cure, some of our most devastating diseases and conditions. To regenerate a severed spinal cord and lift someone from a wheelchair. To spur insulin production and spare a child from a lifetime of needles. To treat Parkinson's, cancer, heart disease and others that affect millions of Americans and the people who love them. But that potential will not reveal itself on its own. Medical miracles do not happen simply by accident. They result from painstaking and costly research -- from years of lonely trial and error, much of which never bears fruit -- and from a government willing to support that work.

BARACK OBAMA, remarks at signing of Stem Cell Executive Order and Scientific Integrity Presidential Memorandum, March 9, 2009

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Wise public policy concerning embryonic stem cell research must attend to three important -- sometimes competing -- responsibilities: to seek scientific knowledge and cures for terrible diseases, to protect human life in all its vulnerable stages, and to respect the diverse yet deeply held moral views of the American people.

LEON R. KASS, "Playing Politics With the Sick", Washington Post, October 8, 2004

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The supporters of embryo-destructive research want to cross a great moral divide. They are seeking not only to destroy human life made in God's image but also to manufacture life made in man's image.

CHUCK COLSON, "The Veto: Should We Cross the Great Moral Divide?", Free Republic, July 21, 2006

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Today, with the Executive Order I am about to sign, we will bring the change that so many scientists and researchers; doctors and innovators; patients and loved ones have hoped for, and fought for, these past eight years: we will lift the ban on federal funding for promising embryonic stem cell research. We will vigorously support scientists who pursue this research. And we will aim for America to lead the world in the discoveries it one day may yield.

BARACK OBAMA, remarks at signing of Stem Cell Executive Order and Scientific Integrity Presidential Memorandum, March 9, 2009

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The bottom line is that there are 400,000 frozen embryos in the United States, and a large percentage of those are going to be thrown out. Regardless of what you think the moral status of those embryos is, it makes sense to me that it's a better moral decision to use them to help people than just to throw them out. It's a very complex issue, but to me it boils down to that one thing. If you really explain what's happening -- that these frozen embryos are ultimately going to be thrown out -- almost everybody except those that have to keep to some kind of party line will say, "What's the problem with this? We should go forward with this."

JAMES THOMSON, "Stem cell pioneer does a reality check", NBC News, June 25, 2005

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While I understand the passion and the conviction of those for whom the blastocyst is a person from the moment of fertilization, I do not believe this, and it is [a] matter of faith for me as well. My passion and my conviction are toward the suffering of the one I see in need, ill or wounded.

LAURIE ZOLOTH, congressional testimony to the Senate Subcommittee on Science, Technology and Space, September 29, 2004

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Stem Cells | Topics | Christianity Today

Posted: September 13, 2016 at 11:46 pm

(UPDATED) ALS raises $100 million in 30 days; pro-life groups worry about embryonic research.

Morgan Lee / August 29, 2014

Biotech advances could make destroying human embryos for research a relic of the past.

Bob Smietana / November 22, 2013

Human cells have been resistant to cloninguntil now.

Christine A. Scheller / May 15, 2013

The new executive director at the Center for Bioethics and Human Dignity discusses recent bioethical debates.

Interview by Alicia Cohn / July 23, 2009

Access to federal money may be mixed blessing for embryonic research.

Sarah Pulliam / April 23, 2009

Why scientific breakthroughs make the destruction of human embryos obsolete.

Rep. Mike Pence / March 23, 2009

When science is made 'apolitical' and 'unencumbered by religion,' it's usually to hyper-politicize and hyper-sacralize it.

Mollie Ziegler Hemingway / March 23, 2009

Where the parties stand on abortion, faith-based programs, religious liberty, and other issues.

August 27, 2008

All three candidates have voted to fund embryonic stem-cell research.

Sarah Eekhoff Zylstra / April 9, 2008

Advances in stem-cell technology cheer and alarm ethics watchers.

Sarah Eekhoff Zylstra / November 16, 2007

Plus: Surgeon general nominee's Methodist work under fire, Time interviews Rowan Williams, church building conflicts, and other stories from online sources around the world.

Compiled by Ted Olsen / June 8, 2007

Why we struggle to gain our moral footing in bioethics.

A Christianity Today Editorial / March 1, 2007

Research advance could shift stem-cell debate.

Sarah Pulliam / February 12, 2007

Fear of mortality lies at the root of our bioethics confusion.

A Christianity Today Editorial / January 2, 2007

It's hard to see the humanity of tiny embryos if we live by blind faith.

Stan Guthrie / November 9, 2006

Embryonic stem cells factor in the race for Henry Hyde's U.S. House seat.

Collin Hansen / November 2, 2006

A new statement from Evangelicals and Catholics Together encourages discourse on the most divisive of issues.

David Neff / October 10, 2006

Plus: Prolifers rally and ... burn the Qur'an?! On having Ralph Reed to kick around, banning baths, and a bunch of links to a bunch of other stories.

Compiled by CT staff / July 21, 2006

Plus: The latest from the Korean cloning scandal.

Nigel M. de S. Cameron / April 27, 2006

The "anti-Genesis" of those who play God, and why the biotech business needs to take ethics seriously.

Nigel M. de S. Cameron / April 19, 2006

Tomorrow's "godlike massively intelligent machines." Plus: Our nanotech future and some good news on stem cells that really work.

Nigel M. de S. Cameron / April 12, 2006

Plus: Good news from Europe on stem-cell funding.

Nigel M. de S. Cameron / April 5, 2006

Plus: The latest on the biopolicy agenda and some outrageous lies on stem cells.

Nigel M. de S. Cameron / March 30, 2006

The U.K. and disaffected American researchers lash out at U.S. cloning laws.

Nigel M. de S. Cameron / March 17, 2006

How to sell unethical science.

Nigel M. de S. Cameron / March 2, 2006

The latest sad story from the Korean soap operaand a lack of Talent in Missouri.

Nigel M. de S. Cameron / February 17, 2006

President Bush sets out a vital agenda for ethics.

Nigel M. de S. Cameron / February 2, 2006

From the frying pan into the fire.

Nigel M. de S. Cameron / January 20, 2006

C. S. Lewis was way ahead of the curve.

by Nigel M. de S. Cameron / November 30, 2005

And they may end up in a laboratory near you.

by Nigel M. de S. Cameron / November 2, 2005

What Americans really think about science: astonishing new polling data.

by Nigel M. de S. Cameron / October 26, 2005

The Majority Leader's contradictions mirror the opinions of the public at large.

by Nigel M. de S. Cameron / October 11, 2005

Remember Prop. 71? Stem-cell research supporters hope voters don't remember the promises they made.

by Nigel M. de S. Cameron / October 5, 2005

The little-known story of the stem cells that actually work.

David A. Prentice / September 30, 2005

What does it mean when even embryonic stem-cell researchers have some qualms about their work?

by Christine A. Scheller / September 29, 2005

Pro-lifers face a scientific and public relations juggernaut.

by Stan Guthrie with Agnieszka Tennant, Sheryl Henderson Blunt in Washington, and Rob James in the United Kingdom / September 28, 2005

The man who led the President's Council on Bioethics brought protests from the industry and directed groundbreaking studies.

by Nigel M. de S. Cameron / September 21, 2005

The Washington Post muddles a major breakthrough in adult stem-cell research, while the U.K. marches blindly on.

by Nigel M. de S. Cameron / August 29, 2005

Introducing our new life ethics weblog.

by Nigel M. de S. Cameron / August 10, 2005

Killing human embryos for research is not pro-life.

by Stan Guthrie / August 2, 2005

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Stem Cell Therapy In Springfield, Missouri – Cherry Health …

Posted: August 8, 2016 at 5:45 am

What Is Stem Cell Therapy

Stem cells are undifferentiated cells that have the ability to replace dying cells and regenerate damaged tissue. A high concentration of these cells are obtained from the patients own bone marrow or fat tissues (adipose) or from a purified amnionic tissue. Our practice uses a sterile closed surgical process to obtain the stem cells. Once obtained, the cells are isolated with a specialized centrifuge and then injected into the painful area on the same day using special imaging to make sure the cells are placed exactly where they are needed.

Adult stem cells usually remain dormant unless they detect some kind of tissue injury. Then the undifferentiated stem cells are called to areas of injury where they are capable of regenerating healthy cells. Sometimes our bodys own healing response is not enough. Thats when a concentrated source of stem cells is needed. Stem cell therapy obtains high concentrations of cells to create an environment for the body to heal itself without the need for medications or steroid injections. When stem cells are injected into an area of injury, they enable the bodys natural healing processes to be dramatically accelerated. The cells can stimulate the formation of many different types of tissue including cartilage, tendon, ligaments, bone and fibrous connective tissues.

The physicians at Cherry Health Center strongly believe that no one should have to live in pain. Cherry Health Center physicians will take the time to educate patients about their conditions and their available treatment options so they can make the best decisions aout their care. Each patient will receive individualized treatment based on their specific needs to ensure the best possible outcome.

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