Posted: August 31, 2014 at 11:43 am
Crayfish Turn Blood Cells into Neurons
Crayfish have a unique way of generating brain cells- they can actually create them from blood cells, rather than from stem cells like most other animals. It #39;s a perplexing development even...
By: NerdAlert
Excerpt from:
Crayfish Turn Blood Cells into Neurons - Video
Posted: August 30, 2014 at 8:52 pm
Researchers at the University of Minnesota have developed an animal research model for facioscapulohumeral muscular dystrophy (FSHD) to be used for muscle regeneration research as well as studies of the effectiveness of potential therapies for FSHD.
The research is published in the current edition of the journal Cell Reports.
There is no treatment for FSHD, which is thought by many to be the most common type of muscular dystrophy. FSHD is an unusual genetic disorder because, unlike most genetic diseases, it is not caused by the loss of a functional gene, but rather by the modification of an existing gene, through a genetic mutation. This mutation makes the gene more active so patients with FSHD express a protein, named DUX4, which interferes in an unknown way with muscle maintenance.
"We felt that an animal model would advance progress towards a cure for FSHD for two reasons," said Michael Kyba, Ph.D., lead researcher and associate professor in the Medical School at the University of Minnesota. "First, it would allow us to understand what DUX4 does in muscle to cause muscle loss, and second, it would provide a system in which efficacy of potential therapies could be evaluated before they are tested in humans."
The mouse model designed by Kyba and his team allows the disease-associated DUX4 protein to be produced when mice are treated with doxycycline. The amount of DUX4 can be controlled by varying the dose of doxycycline. Researchers expected the mice to be normal until they were treated with doxycycline, however even when DUX4 was in the "off" state, mice showed profound disease effects, some related to FSHD as well as additional effects not seen in FSHD patients.
"Nothing is black and white in biology," says Kyba. "No gene is truly off, and the off state in this case resulted in enough leaky DUX4 expression to kill the mice."
The team solved this problem by moving the gene to the X chromosome. Because females have two X chromosomes, only one of which is actively used in each cell, the female mice were healthy enough to enable the DUX4 mice to reproduce even though all of their male progeny with the DUX4 gene died. The fact that multiple levels of turning off the DUX4 gene were necessary to allow mice to survive showed that DUX4 is more toxic than researchers expected.
"We learned a lot with this animal model, but perhaps the most important finding was what we observed when we transplanted skeletal muscle stem cells," said Kyba.
The team could isolate muscle stem cells from the male mice before they died and when they transplanted them into muscle-damaged recipient mice, they found that the stem cells were able to regenerate new muscle. But when even low doses of doxycycline were given to the recipients to turn on DUX4 in the skeletal muscle stem cells, muscle regeneration was severely impaired. This suggested that a defect in skeletal muscle regeneration may contribute to muscle loss in FSHD. The finding also provides a very sensitive quantitative readout of DUX4 activity.
"This assay, in which we count new muscle fibers produced by transplanted DUX4-expressing muscle stem cells, will be very useful in testing therapeutics," says Kyba. "Drugs that target DUX4 should allow these transplanted DUX4-expressing muscle stem cells to make more new muscle fibers."
Go here to see the original:
Researchers find animal model for understudied type of muscular dystrophy
Posted: August 30, 2014 at 8:49 pm
Looking for help with Akinetic Mutism in Fairbanks? Listed below are doctors and medical centers in and near Fairbanks Alaska.
If you are not looking for help with Akinetic Mutism, check out the popular Akinetic Mutism info on the right navigation area of the page. On the Akinetic Mutism pages we include website links so you can check out Akinetic Mutism online.
Are you searching for information about Akinetic Mutism? Have you or someone you know been diagnosed with Akinetic Mutism? Have you considered Stem Cell treatments for Akinetic Mutism? Welcome to the stem cell center service for the state of KY! Many diseases and illnesses don't have to be as treacherous as once thought. There are potential cures and treatments available that are quite effective and very hopeful for Akinetic Mutism If you are ready to consider adult stem cell treatment and adult stem cell therapy as an alternative for your medical disorder Akinetic Mutism, then you are at the right place. Here at alternativetreatmentsfor.com we specialize in providing effective stem cells for Akinetic Mutism in or near Fairbanks, KY 99707. For immediate, free, and confidential assistance, download or .pdf file and call our helpline NOW!
Are you searching for a stem cell? Have you or someone you know been diagnosed with Akinetic Mutism ? Welcome to the stem cell center service for the state of Alaska! Many diseases and illnesses are more treatable than most people once thought. There are many potential cures - stem cells and treatments available that have proven to be quite effective and very hopeful for Akinetic Mutism
If you are open to the idea of adult stem cell treatment and adult stem cell therapy as an alternative method of treatment for your medical disorder Akinetic Mutism, then you have found the right place. Here at naturalcurefor.com we specialize in helping people heal by providing effective and stem cells for Akinetic Mutism in or near Fairbanks, Alaska 99707. For immediate, free, and confidential assistance, download our .pdf file and call our helpline NOW!
We have successfully helped many people in Alaska. We can help you attain real, effective, stem cells and alternative treatments for Akinetic Mutism. Health improvements after our natural method of treatments have been used have shown terrific results in a very high percentage of cases. Every human being deserves to have good health and that is our desire to sincerely provide a network of resources available to help you or your loved one achieve better health. Don't let another day or week go by. Don't think that the pain or the Akinetic Mutism you or a loved one have endured cannot be ended or put on a better more natural healing path to good health. Don't give up hope. We can help you recover, but you have to take the first step by contacting us now!
Fairbanks, Alaska - Stem cell for Akinetic Mutism - We Can Provide Some Tremendous Hope if You Are Willing to Consider Adult Stem Cell Therapy and Treatments as Your Path Back To Good Health
Treating Akinetic Mutism in a traditional medical manner is sometimes a long and grueling process that can offer less hope than you deserve. Additionally, many traditional medical treatments are riddled with drugs and medications that can sometimes cause even more harm to other parts of the body. Further risks of medication mixups, allergies, destruction of the immune system and the constant level of additional medical treatments that may be required, can sometimes weigh heavily on a patient and their chances of regaining a healthful way of life. Recovery can become difficult or almost impossible in some cases.
We offer an alternative treatment or a more stem cell process that centers around the idea of using your own adult stem cells as the basis of this natural treatment. In some areas of the country, traditional medicine and medical practices may not have acknowledged the benefits that stem cell treatments can bring to the healing process. Stem cell treatments may not be a standard course of medical treatment quite yet, but that may be a result of other political and/or profit motives. But rest assured that is all changing and changing quite rapidly as more and more success and overwhelming evidence indicates that adult stem cell therapy is a very successful and viable treatment process for Akinetic Mutism.
Stem cell treatment is extremely effective and very safe. It is also very natural, ethical and a very effective way in assisting the body to heal naturally and wholesomely. It embodies the very idea of "healing" rather than simply medicating a symptom. The main idea of how adult stem cell treatments work are as follows...
Read more:
Stem cell therapy for Akinetic Mutism in Fairbanks Alaska
Posted: August 30, 2014 at 12:40 pm
Regenerative Medicine with PRP and Stem Cells at San Diego Center for Integrative Medicine
http://SDIntegrativeMedicine.com Regenerative medicine via platelet-rich plasma (PRP) and stem cells is more effective when used prior to surgery.
By: San Diego Center for Integrative Medicine
Follow this link:
Regenerative Medicine with PRP and Stem Cells at San Diego Center for Integrative Medicine - Video
Posted: August 30, 2014 at 12:40 pm
Duane Hatfield ice bucket challenge
I was challenged by Isaac Hatfield and Herstle Wayne Davis to do the ALS ice bucket challenge. I did some research on the ALS Association found out they use embryonic stem cells for their research...
By: Duane Hatfield
See the article here:
Duane Hatfield ice bucket challenge - Video
Posted: August 30, 2014 at 12:40 pm
ALS Ice Bucket Challenge
It was COOOOOOOOLD!!! Please consider making your donation pro life: http://www.lifenews.com/2014/08/21/send-your-ice-bucket-challenge-donation-to-ethical-successful-adult-stem-cell-research/...
By: TheStringbox
Continued here:
ALS Ice Bucket Challenge - Video
Posted: August 30, 2014 at 12:40 pm
Bishop Daniel Thomas addresses ALS Ice Bucket Challenge and stem cell research
Bishop Daniel E. Thomas says those donating to ALS research through the Ice Bucket Challenge should be aware that some money may go towards stem cell researc...
By: NBC 24 WNWO
View original post here:
Bishop Daniel Thomas addresses ALS Ice Bucket Challenge and stem cell research - Video
Posted: August 30, 2014 at 12:40 pm
Pro-life ice bucket challenge
ALS ice bucket challenge for pro-life people who can #39;t donate to embryonic stem cell research in good conscience.
By: Thomas Rice
Read the original post:
Pro-life ice bucket challenge - Video
Posted: August 30, 2014 at 12:40 pm
ALS Challenge
Dusty and Braden were challenged to do the ALS ice bucket challenge... However, we cannot support their practice of stem cell research. They decided to donate to http://www.gospelministry.org.
By: Andrea Schellenberg
Link:
ALS Challenge - Video
Posted: August 30, 2014 at 12:40 pm
Laura #39;s Ice Bucket Challenge LEGO Style
Please note that it is possible to donate to ALS research and request that your donation not be used towards stem cell research. #begooddogood #IceBucketChallenge.
By: laurelcrowned144000
Read the original here:
Laura's Ice Bucket Challenge LEGO Style - Video
