By expanding the use of adipose tissue and its stem cell    components, scientist and surgeons have made significant    strides in aesthetic and reconstructive surgery. The    opportunities for regenerative medicine interventions based on    adult stem cells are tremendous  IvonaPercec, MD, PhD  
    As researchers work on reconfiguring cells to take on new    regenerative properties, a new review from Penn Medicine    plastic surgeons sheds additional light on the potential power    of adipose-derived stem cells  or adult stem cells harvested    from fatty tissue  in reconstructive and regenerative    medicine.  
    Fat-derived stem cells hold potential for regenerative medicine    November 9, 2012 in Surgery (Medical Xpress)As researchers    work on reconfiguring cells to take on new regenerative    properties, a new review from Penn Medicine plastic surgeons    sheds additional light on the potential power of    adipose-derived stem cells  or adult stem cells harvested from    fatty tissue  in reconstructive and regenerative medicine.  
    Reconstructive plastic surgeons have clinically integrated fat    grafting into different surgeries for years, for breast,    facial, and other reconstructive and restorative surgeries,    with good success. Now, researchers are beginning to understand    the power that fatty tissue holds. This new paper, published in    the Aesthetic Surgery Journal, enforces that adipose-derived    stem cells can be routinely isolated from patients, and once    molecular methods are worked out, may be useful for a multitude    of regenerative medicine applications. The opportunities for    regenerative medicine interventions based on adult stem cells    are tremendous. It is critically important for us to better    understand the biology of these cells so that we can develop    novel, safe and effective treatments for our patients using    their own cells. said the papers senior author,    IvonaPercec, MD, PhD, assistant professor in the division    of Plastic Surgery in the Perelman School of Medicine at the    University of Pennsylvania.  
    Many groups are looking into different modes of isolating and    modifying these cells for their regenerative properties,    including experts at Penns Institute for Regenerative Medicine    and around Penn Medicine. For example, Dr. Percecs team is    conducting translational research into the mechanisms    controlling adipose-derived stem cells, and how they contribute    to the normal human aging process. Stem cells can undergo    multiple divisions without differentiation, making them useful    tools for cell-replacement therapy. Embryonic stem cells can    convert to any cell type, whereas adult stem cells, like the    stem cells derived from fat, can differentiate into many, but    not all, cell types. A persons own fat tissue could then    potentially be converted into cells specially designed to    repair damage to the heart, cartilage, blood vessels, brain,    muscle, or bone. As regenerative medicine techniques are    refined, experts will continue to explore the utility and    benefits of stem cells derived from adipose tissue.  
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