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Cancer stem cells – University of Michigan Comprehensive …

Posted: July 25, 2016 at 5:42 am

Cancer stem cells are the small number of cells within a tumor that drive the tumor's growth. These cells generally make up just 1% to 3% of all cells in a tumor Watch the video with Max Wicha, M.D., director emeritus of the University of Michigan Comprehensive Cancer Cancer and learn more about stem cell research

If you are having trouble viewing the video, watch it on our YouTube channel.

At the U-M Comprehensive Cancer Center, we believe treatments designed to target and destroy cancer stem cells will revolutionize how we treat cancer. Over the last 30 years, researchers have developed more effective treatments for cancers like childhood leukemia, Hodgkin's disease and testicular cancer.

Death rates for some common cancers, like breast and prostate cancer, have gone down due to advances in early detection and prevention. However, the survival rate for patients with many advanced cancers has not changed significantly for decades, and cancer is still the second-most common cause of death in the United States.

Instead of trying to kill all the cells in a tumor with chemotherapy or radiation, we believe it would be more effective to use treatments targeted directly at these so-called cancer stem cells. If the stem cells were eliminated, the cancer would be unable to grow and spread to other locations in the body.

The U-M Comprehensive Cancer Center is one of only a few research institutions in the United States and Canada that has made an institutional commitment to cancer stem cell research.

Organized teams of U-M scientists are studying cancer stem cells in many different types of cancer:

By working together and sharing information, Cancer Center scientists hope to make progress more rapidly than would be possible for individual scientists working alone.

We believe new treatments designed to target and destroy cancer stem cells could revolutionize the way physicians treat cancer. Our goal is to be the world's leader in research on cancer stem cells and in the development of new stem cell-based therapies for cancer patients.

Every organ and type of tissue in the body contains a small number of what scientists call "adult" or "tissue" stem cells. Since most cells in the body live for just a short time, the body needs to keep making new cells to replace them.

Adult stem cells ensure a continuous supply of new cells to replace old cells that wear out or are destroyed.

In 2003, U-M scientists were the first in the world to identify cancer stem cells in a solid tumor, finding them in breast tumors. Since then, other Cancer Center scientists have discovered and isolated cancer stem cells in pancreatic cancer (2007), in head and neck cancer (2007) and in an aggressive brain cancer called glioblastoma (2009).

Even under a microscope, there's no way to distinguish cancer stem cells from other malignant cells just by looking at them. To identify stem cells, scientists use specialized equipment to detect specific proteins on the cell's surface.

These proteins are not found on regular cancer cells. A biochemical assay developed at the U-M Cancer Center can identify breast cancer stem cells.

The ultimate test to prove that cells are true cancer stem cells is to inject cells from a human tumor into mice that are genetically engineered to lack a cancer-fighting immune system. If the mouse does not get cancer, scientists know the injected cells were not stem cells, because ordinary tumor cells will divide a few times and then die. But if the mouse develops a tumor with the same types of cells as the human tumor, scientists know that the injected cells were true cancer stem cells.

By analyzing the genes that are active in a patient's cancer stem cells and counting the number of stem cells in a tumor, physicians could identify patients at high risk for advanced, aggressive disease.

New therapies designed to target stem cells could eliminate cancer without the risks and side effects of current treatments that also destroy healthy cells in the body. Destroying cancer stem cells in the original tumor could reduce the risk of deadly metastasis, where malignant cells move from the primary tumor to other places in the body. Finally, by killing the cells driving the tumor's growth, treatments targeted at cancer stem cells could eliminate recurrences of the disease.

Scientists don't know for sure. Since chemotherapy and radiation kill cells that divide often, stem cells may be less vulnerable because they rarely divide. Some scientists believe cancer stem cells may have genetic mutations that make them resistant to damage from chemotherapy or radiation, or cancer stem cells may be able to repair DNA damage more rapidly than normal cells.

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Updated 06.2016

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Rob Waddell Defeats Kidney Disease – Adult Stem Cells

Posted: July 25, 2016 at 5:41 am

Rob Waddell Defeats Kidney Disease

Rob Waddell knew at an early age that he would need a kidney transplant. His mother has had two transplants and polycystic kidney disease runs in his family. "Ive had two uncles thatve died from this disease. At early ages. I mean they went on dialysis, they had a transplant, something happened, theyre no longer here. Their kids are, without, without a dad!", Rob said.

So when his doctor told him he had to go on dialysis and that a transplant was imminent it was no surprise. Having watched his mother suffer the ups and downs of taking anti-rejection drugs her whole life, he was thrilled to find out there was another option. He entered a clinical trial whereby he would receive an adult stem cell transplant from his kidney donor at the time of the kidney transplant surgery. The donors adult stem cells would allow Rob to accept the same donors kidney, essentially re-training his immune system so that it would recognize the donor kidney as part of Robs own body.

Rob says, "Well, I decided to do the stem cell transplant because I didnt want to live the rest of my life on immune rejection drugs. The good and the bad of immune suppressant drugs is they let the kidney stay in your body. The bad part is that slowly over time it kills the kidney. Its toxic to the kidney. So those drugs, over time, will cause the kidney to fail. My wife, Karen, she, when I proposed the idea of me doing this stem cell study, she was really kind of concerned. I mean she didnt want me to do it because it was new."

Karen Waddell remembers what she said when she heard about the adult stem cell transplant, "I told him I was totally against it from the beginning. Didnt like it. I said, you can just have a normal transplant. Your mom has lived through it. You know, well just adjust."

Rob says, "Seeing my mother go through the repercussions of having kidney disease and the transplant and immune rejection drugs, probably was the number one foundation for me pursuing this."

After the stem cell infusion, Karen says, Rob was like a new man. "Its like hes rejuvenated. Its amazing. He's alert. All his faculties are working great. And for him to be just drug-free, oh its wonderful!

"We call him my fifth child and other people that know us too, theyll tease, because you will see him rip-sticking around the neighborhood, or on the trampoline. So Im thankful that he was able to just be determined and have that drive and the foresight to know that he was going to get those stem cells.

Today Rob lives a full and active life chasing four kids around the soccer, baseball and lacrosse fields of Louisville, Kentucky.

"I feel so fortunate, because Ive been blessed with this. I mean truly a new lease on life. I feel fantastic. My kids could tell you that. I mean I wear them out half the time and I didnt before.

Actually, almost every day since then, I just walk around and Im like, Wow! I feel so goodI mean is this really happening? These adult stem cells to me were a chance to live a normal life.and its amazing."

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Indiana (Stem Cell) – what-when-how

Posted: July 25, 2016 at 5:40 am

Indiana is working to establish itself as a leader in nonembryonic stem cell research to avoid the conflicts associated with embryonic stem cell research. Thus, researchers have supportive legislation and funding, as well as public support, with a goal of improving the economy in the biotechnology sector.

As no federal legislation in the United States regulates stem cell research (except by an executive order to not allow federal funding to be used for embryonic stem cell research except on human embryonic stem cell lines created before August 9, 2001), each state is responsible for determining policy and funding for stem cell research. In Indiana, stem cell research is permitted on adult stem cells and fetal stem cells if consent is received from the biological parent. Indiana prohibits research on human embryonic stem cells in accordance with Indiana code 31-20-2, regarding embryos from assisted reproduction. The law also prohibits the sale of oocytes, zygotes, embryos, and fetuses.

In 2007 the Indiana legislature also approved the establishment of an Adult Stem Cell Research Center at Indiana University and gave the Indiana University School of Medicine approval to administer the center, including appointing a director and accepting income from donations, gifts, and so on, to be used to support the centers activities.

BioCrossroads is a development organization to enhance economic growth in the life sciences. The organization provides money and support to business start-ups and established businesses in biotechnology by providing networking and collaboration opportunities among Indianas various academic, clinical, and industry institutions. Money is available through the Indiana Future Fund and the Indiana Seed Fund

Other services provided by BioCrossroads include the Indiana Health Information Exchange, which facilitates the sharing of clinical information among healthcare providers and other healthcare entities, and the Translational Research Initiative partnership with Indiana University, which leverages resources in promoting life science research to gain national and private grant funding.

Indiana University-Purdue University in Indianapolis was founded in 1969. The university offers bachelors, masters, doctoral, and professional degrees in a variety of disciplines including medicine, biology, engineering, math, and physical sciences. The university is home to the Indiana University School of Medicine.

The Adult Stem Cell Research Center to be established at Indiana University will fall under the purview of the School of Medicine to encourage collaboration among all of Indianas stem cell researchers. Research being done or completed by the university includes the discovery of cells that control the creation of endothelial cells and investigating the possibility of using these cells for medical treatment for circulation problems in the extremities, for heart disease, and for repair of blood vessels, and to use adult stem cells to alleviate diseases secondary to increasing age,

The Emerging Technology Center in Indianapolis allows the university to assist business startups using discoveries made by researchers at the university. EndGenitor Technologies Inc. is one such firm and has capitalized on the research performed by university professors. The start-up company intends to develop and market test kits for researchers to test samples for endothelial stem and progenitor cells.

The Indiana Cord Blood Bank collects, preserves, and stores cord blood as a source of adult stem cells for use in blood transplants for treating blood diseases and cancers, anemia, inherited metabolic disorders, and immune system deficiencies.

The Bindley Bioscience Center opened in 2005 through funding provided by a Purdue alumnus to integrate the life sciences and engineering departments for cross-discipline research at the university. The speciality of the center is basic research with a focus on translating this research to clinical application for testing, diagnosis, and treating human disease, including tissue engineering for use in regenerative medicine.

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Stem Cells in Lung Cancer | California’s Stem Cell Agency

Posted: July 25, 2016 at 5:35 am

Statement of Benefit to California:

According to the Center for Health Statistics, California Department of Health Services, 13,427 people died of lung cancer in the state of California in 2005. This is more than the deaths attributed to breast, prostate and colon cancers combined. The devastating effects of this disease on the citizens of California and the health care costs involved are enormous. Most cases of lung cancer occur in smokers, but non smokers, people exposed to second hand smoke and ex-smokers are also at risk. In addition, of special concern to California residents, is that exposure to air pollution is associated with an increased risk of lung cancer. Current therapeutic strategies for lung cancer are in general only able to prolong survival by a few months, especially for late stage disease. One reason for this may be that the cancer initiating stem cell is resistant to these therapies. Understanding the stem cell populations involved in repair of the lung and how these cells may give rise to lung cancer is important for potentially generating new therapeutic targets for lung cancer. We propose to study the stem cell populations of the lung that are crucial for normal airway repair and characterize the putative cancer initiating stem cell in the lung. We have also found stem cells in the blood that are critical for normal airway repair and we plan to test their role in the prevention of premalignant lung cancer lesions. We also plan to test whether levels of these stem cells in the blood may be used as a biomarker of lung cancer. Ultimately, the ability to perform a screening test to detect lung cancer at an early stage, and the development of new therapies for lung cancer will be of major benefit to the citizens of California.

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About Adipose Stem Cell Therapy

Posted: July 25, 2016 at 5:34 am

Adipose Stem Cell Therapy

What is an Autologous Adipose Stem Cell Procedure?

A small sample of Adipose tissue (fat) is removed from above the Superior Iliac spine (love handles) or abdomen under a local anesthetic.

Obtaining Adipose-Derived Stem Cells (ADSCs) is much easier and less invasive than performing abone marrowextraction. In addition, adipose tissue contains much larger volumes of mesenchymal stem cells than does bone marrow. We use the patient's own adipose tissue to extract the stem cells. Autologous meansthat the donor and the recipient are the same person.

Benefits of ADSCs: Stem cells play an integral part in wound healing and regeneration of tissue at the cellular level.

The Major Advantages of Adipose Stem Cell Therapy:

Is this procedure a significant improvement on other treatments currently available?

Yes We can now obtain Adult Stem Cells (ASCs) from a fat sample. This in-clinic treatment is completed the same day, and there is no need to ship samples to an outside laboratory and wait days for the cells to be returned for an injection on a second visit. This faster process provides increased stem cell counts, without manipulation.

Is an Autologous Adipose Stem Cell Procedure Safe?

Yes because the adipose tissue is removed from one's own body via sterile technique and remains in a controlled environment there are no problems with cell rejection or disease transmission. The interview, physical, harvesting, and administration of stem cells are all performed in-house under a physicians control.

How do I know if stem cell therapy is right for me?

Discussing treatment options with your physician is an important first step in making a decision regarding stem cell therapy. Potential outcomes, an integrative and comprehensive treatment plan, and financial costs are all factors to consider.

I have heard Stem Cell Treatments are VERY expensive, can I afford this?

Yes you can!

Due to our advanced adult stem cell technology provided in the form of an in house procedure, our Stem Cell Center can now provide this service at a fraction of the cost previously incurred. Even better, its a same day procedure.We offer theentirety of our treatment in Phoenix, Arizona -USA and we have been able to lower our cost to a flat rate of $7,100.00 per treatment (including consultation). Fees are subject to change and some more complex proceduresmay incur additional costs.

Why Choose an Adipose Stem Cell Procedure?

Adipose-derived mesenchymal stem cells areeasier to harvest than bone marrowand can be obtained in much larger quantities. In addition, it is much less painful and involves lower risks.

*There is a much shorter time from extraction to the administration oftreatment.No culturing or manipulation is needed using our procedure, as opposed to a bone marrow extraction which requires days or weeksto reach the necessary therapeutic threshold.

*There are no ethical or moral issues involved in harvesting autologous Adult Stem Cells (ASCs).

Are There Detrimental Side Effects from an Adipose Stem Cell Procedure?

No, the adipose tissue is extracted from the patients own body sono foreign donors are used. This minimizes the potential for immune rejection.Our procedure is performed completely in-house and administered by licensed physicians here in the United States. Please keep in mind that every procedure does have its risks, but we do practice sterile technique which makes the risk of infectionvery low.In fact, we have not had any infections develop in any of the stem cell patients we have treated as we take great care in keeping a sterile environment.

What You Can Expect When Visiting the Stem Cell Rejuvenation Center:

Differences Between An Adipose And A Bone Marrow Procedure:

Autologous Growth Factor Components of PRP:

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Biotechnology Salaries – Salary.com

Posted: July 25, 2016 at 5:34 am

Category: Accounting Administrative, Support, and Clerical Advertising Aerospace and Defense Agriculture, Forestry, and Fishing Architecture Arts and Entertainment Automotive Aviation and Airlines Banking Biotechnology Clergy Construction and Installation Consulting Services Customer Services Education Energy and Utilities Engineering Entry Level Environment Executive and Management Facilities, Maintenance, and Repair Financial Services Fire, Law Enforcement, and Security Food, Beverage, and Tobacco Government Graphic Arts Healthcare -- Administrative Healthcare -- Nursing Healthcare -- Practitioners Healthcare -- Technicians Hotel, Gaming, Leisure, and Travel Human Resources Insurance Internet and New Media IT -- All IT -- Computers, Hardware IT -- Computers, Software IT -- Executive, Consulting IT -- Manager IT -- Networking Legal Services Library Services Logistics Manufacturing Marketing Materials Management Media -- Broadcast Media -- Print Military Mining Non-Profit and Social Services Personal Care and Service Pharmaceuticals Planning Printing and Publishing Public Relations Purchasing Real Estate Restaurant and Food Services Retail/Wholesale Sales Science and Research Skilled and Trades Sports and Recreation Telecommunications Training Transportation and Warehousing

Industry: ALL Aerospace & Defense Biotechnology Business Services Chemicals Construction Edu., Gov't. & Nonprofit Energy & Utilities Financial Services Healthcare Hospitality & Leisure Insurance Internet Media MFG Durable MFG Nondurable Pharmaceuticals Retail & Wholesale Software & Networking Telecom Transportation

Income Level: All $100,000+ $80,000 - $100,000 $50,000 - $80,000 $30,000 - $50,000 $10,000 - $30,000

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Biotechnology | Define Biotechnology at Dictionary.com

Posted: July 25, 2016 at 5:34 am

British Dictionary definitions for biotechnology Expand

/batknld/

(in industry) the technique of using microorganisms, such as bacteria, to perform chemical processing, such as waste recycling, or to produce other materials, such as beer and wine, cheese, antibiotics, and (using genetic engineering) hormones, vaccines, etc

Derived Forms

biotechnological (batknldkl) adjectivebiotechnologically, adverbbiotechnologist, noun

Word Origin and History for biotechnology Expand

also bio-technology, 1947, "use of machinery in relation to human needs;" 1972 in sense of "use of biological processes in industrial production," from bio- + technology.

biotechnology in Medicine Expand

biotechnology biotechnology (b'-tk-nl'-j) n.

The use of microorganisms, such as bacteria or yeasts, or biological substances, such as enzymes, to perform specific industrial or manufacturing processes. Applications include production of certain drugs, synthetic hormones, and bulk foodstuffs.

The application of the principles of engineering and technology to the life sciences.

biotechnology in Science Expand

The use of a living organism to solve an engineering problem or perform an industrial task. Using bacteria that feed on hydrocarbons to clean up an oil spill is one example of biotechnology.

The use of biological substances or techniques to engineer or manufacture a product or substance, as when cells that produce antibodies are cloned in order to study their effects on cancer cells. See more at genetic engineering.

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Diabetes: Symptoms, Causes and Treatments – Health News

Posted: July 25, 2016 at 5:32 am

knowledge center home diabetes what is diabetes?

Diabetes, often referred to by doctors as diabetes mellitus, describes a group of metabolic diseases in which the person has high blood glucose (blood sugar), either because insulin production is inadequate, or because the body's cells do not respond properly to insulin, or both. Patients with high blood sugar will typically experience polyuria (frequent urination), they will become increasingly thirsty (polydipsia) and hungry (polyphagia).

Fast facts on diabetes

Here are some key points about diabetes. More detail and supporting information is in the main article.

This information hub offers detailed but easy-to-follow information about diabetes. Should you be interested in the latest scientific research on diabetes, please see our diabetes news section.

There are three types of diabetes:

The body does not produce insulin. Some people may refer to this type as insulin-dependent diabetes, juvenile diabetes, or early-onset diabetes. People usually develop type 1 diabetes before their 40th year, often in early adulthood or teenage years.

Type 1 diabetes is nowhere near as common as type 2 diabetes. Approximately 10% of all diabetes cases are type 1.

Patients with type 1 diabetes will need to take insulin injections for the rest of their life. They must also ensure proper blood-glucose levels by carrying out regular blood tests and following a special diet.

Between 2001 and 2009, the prevalence of type 1 diabetes among the under 20s in the USA rose 23%, according to SEARCH for Diabetes in Youth data issued by the CDC (Centers for Disease Control and Prevention). (Link to article)

More information on type 1 diabetes is available in our type 1 diabetes page.

The body does not produce enough insulin for proper function, or the cells in the body do not react to insulin (insulin resistance).

Approximately 90% of all cases of diabetes worldwide are type 2.

Some people may be able to control their type 2 diabetes symptoms by losing weight, following a healthy diet, doing plenty of exercise, and monitoring their blood glucose levels. However, type 2 diabetes is typically a progressive disease - it gradually gets worse - and the patient will probably end up have to take insulin, usually in tablet form.

Overweight and obese people have a much higher risk of developing type 2 diabetes compared to those with a healthy body weight. People with a lot of visceral fat, also known as central obesity, belly fat, or abdominal obesity, are especially at risk. Being overweight/obese causes the body to release chemicals that can destabilize the body's cardiovascular and metabolic systems.

Being overweight, physically inactive and eating the wrong foods all contribute to our risk of developing type 2 diabetes. Drinking just one can of (non-diet) soda per day can raise our risk of developing type 2 diabetes by 22%, researchers from Imperial College London reported in the journal Diabetologia. The scientists believe that the impact of sugary soft drinks on diabetes risk may be a direct one, rather than simply an influence on body weight.

The risk of developing type 2 diabetes is also greater as we get older. Experts are not completely sure why, but say that as we age we tend to put on weight and become less physically active. Those with a close relative who had/had type 2 diabetes, people of Middle Eastern, African, or South Asian descent also have a higher risk of developing the disease.

Men whose testosterone levels are low have been found to have a higher risk of developing type 2 diabetes. Researchers from the University of Edinburgh, Scotland, say that low testosterone levels are linked to insulin resistance. (Link to article)

For more information on how type 1 and type 2 diabetes compare, see our article: the difference between type 1 and type 2 diabetes.

More information on type 1 diabetes is available in our type 2 diabetes page.

This type affects females during pregnancy. Some women have very high levels of glucose in their blood, and their bodies are unable to produce enough insulin to transport all of the glucose into their cells, resulting in progressively rising levels of glucose.

Diagnosis of gestational diabetes is made during pregnancy.

The majority of gestational diabetes patients can control their diabetes with exercise and diet. Between 10% to 20% of them will need to take some kind of blood-glucose-controlling medications. Undiagnosed or uncontrolled gestational diabetes can raise the risk of complications during childbirth. The baby may be bigger than he/she should be.

Scientists from the National Institutes of Health and Harvard University found that women whose diets before becoming pregnant were high in animal fat and cholesterol had a higher risk for gestational diabetes, compared to their counterparts whose diets were low in cholesterol and animal fats. (Link to article)

See the next page of our article for a full list of possible diabetes symptoms.

The vast majority of patients with type 2 diabetes initially had prediabetes. Their blood glucose levels where higher than normal, but not high enough to merit a diabetes diagnosis. The cells in the body are becoming resistant to insulin.

Studies have indicated that even at the prediabetes stage, some damage to the circulatory system and the heart may already have occurred.

Diabetes (diabetes mellitus) is classed as a metabolism disorder. Metabolism refers to the way our bodies use digested food for energy and growth. Most of what we eat is broken down into glucose. Glucose is a form of sugar in the blood - it is the principal source of fuel for our bodies.

When our food is digested, the glucose makes its way into our bloodstream. Our cells use the glucose for energy and growth. However, glucose cannot enter our cells without insulin being present - insulin makes it possible for our cells to take in the glucose.

Insulin is a hormone that is produced by the pancreas. After eating, the pancreas automatically releases an adequate quantity of insulin to move the glucose present in our blood into the cells, as soon as glucose enters the cells blood-glucose levels drop.

A person with diabetes has a condition in which the quantity of glucose in the blood is too elevated (hyperglycemia). This is because the body either does not produce enough insulin, produces no insulin, or has cells that do not respond properly to the insulin the pancreas produces. This results in too much glucose building up in the blood. This excess blood glucose eventually passes out of the body in urine. So, even though the blood has plenty of glucose, the cells are not getting it for their essential energy and growth requirements.

Doctors can determine whether a patient has a normal metabolism, prediabetes or diabetes in one of three different ways - there are three possible tests:

Diabetes comes from Greek, and it means a "siphon". Aretus the Cappadocian, a Greek physician during the second century A.D., named the condition diabainein. He described patients who were passing too much water (polyuria) - like a siphon. The word became "diabetes" from the English adoption of the Medieval Latin diabetes.

In 1675, Thomas Willis added mellitus to the term, although it is commonly referred to simply as diabetes. Mel in Latin means "honey"; the urine and blood of people with diabetes has excess glucose, and glucose is sweet like honey. Diabetes mellitus could literally mean "siphoning off sweet water".

In ancient China people observed that ants would be attracted to some people's urine, because it was sweet. The term "Sweet Urine Disease" was coined.

All types of diabetes are treatable. Diabetes type 1 lasts a lifetime, there is no known cure. Type 2 usually lasts a lifetime, however, some people have managed to get rid of their symptoms without medication, through a combination of exercise, diet and body weight control.

Researchers from the Mayo Clinic Arizona in Scottsdale showed that gastric bypass surgery can reverse type 2 diabetes in a high proportion of patients. They added that within three to five years the disease recurs in approximately 21% of them. Yessica Ramos, MD., said "The recurrence rate was mainly influenced by a longstanding history of Type 2 diabetes before the surgery. This suggests that early surgical intervention in the obese, diabetic population will improve the durability of remission of Type 2 diabetes." (Link to article)

Patients with type 1 are treated with regular insulin injections, as well as a special diet and exercise.

Patients with Type 2 diabetes are usually treated with tablets, exercise and a special diet, but sometimes insulin injections are also required.

If diabetes is not adequately controlled the patient has a significantly higher risk of developing complications.

Below is a list of possible complications that can be caused by badly controlled diabetes:

Written by Markus MacGill. Last updated: 5 January 2016.

Disclaimer: This informational section on Medical News Today is regularly reviewed and updated, and provided for general information purposes only. The materials contained within this guide do not constitute medical or pharmaceutical advice, which should be sought from qualified medical and pharmaceutical advisers.

Please note that although you may feel free to cite and quote this article, it may not be re-produced in full without the permission of Medical News Today. For further details, please view our full terms of use

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Diabetes: Symptoms, Causes and Treatments - Health News

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Diabetes Basics

Posted: July 25, 2016 at 5:32 am

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This is the place to begin your education about diabetes.

This section of our site provides basic overviews of the major issues surrounding diabetes, with plenty of links to more in-depth information if you need it.

Take our type 2 diabetes risk test for a quick assessment of your risk.

There is no way to predict your chances of getting type 1 diabetes, but you can familiarize yourself with its symptoms.

Type 1 diabetes is usually diagnosed in children and young adults, and was previously known as juvenile diabetes.

Expecting? Learn why women who have never had diabetes may be at risk during pregnancy.

The numbers associated with diabetes make a strong case for devoting more resources to finding a cure.

Clear up some common misunderstandings about what causes diabetes, the effects of diabetes, and how diabetes can be managed.

Become familiar with terms commonly used when discussing diabetes.

Pulitzer prize winning photographer Jay Dickman, volunteered his time and talent to photograph three individuals that are living with diabetes to share their up close and personal daily lives.

These well-known men and women have joined the Association's "Celebrity Cabinet" to help stop diabetes.

We Can Help:

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Diabetes Basics

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Texas Research : Stem Cell Cite

Posted: July 17, 2016 at 6:40 am

Posted by admin on November 25, 2014 Leave a Comment

Texans for Stem Cell Research (TSCR), proudly announces its participation in the World Stem Cell Summit, 2014 in San Antonio November 25th, 2014 | Texans for Stem Cell Research (TSCR), proudly announces its participation in the World Stem Cell Summit, 2014 in San Antonio, Texas, December 2-5th, 2014. TSCR will co- host a Welcoming Party for the Genetics Policy Institute, the organizer of the Summit, along with the City of San Antonio and the San Antonio Economic Development Foundation. This event will be held at the San Antonio Convention Center LDR Room, 200 E. Market St. The event will be from 7:30-10:30 pm on December 2, 2014. Featured speakers include Dr. Doris Taylor of the

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February 9, 2014, 7:00 PM|What 60 Minutes Lesley Stahl learned while reporting on the surprising medical differences between males and females Watch 60 Minutes Overtime Recommend on FacebookTell a friend

Posted by admin on January 23, 2014 Leave a Comment

Scientists have known for years that stem cells in male and female sexual organs are regulated differently by their respective hormones. In a surprising discovery, researchers at the Childrens Medical Center Research Institute at UT Southwestern (CRI) and Baylor College of Medicine have found that stem cells in the blood-forming system which is similar in both sexes also are regulated differently by hormones, with estrogen proving to be an especially prolific promoter of stem cell self-renewal. The research, published in Nature, raises several intriguing possibilities for further investigation that might lead to improved treatments for blood cancers and increased safety and effectiveness of chemotherapy. Before the finding, blood-forming stem cells were thought to

Category Blood, Children, Headlines, Pediatric, Stem Cells, Texas, Texas Research Tags Baylor College of Medicine, blood-forming stem cells, Daisuke Nakada, estrogen, Hideyuki Ogur, hildrens Medical Center Research Institute, hormones, Mary McDermott, pediatric genetics, Sean Morrison, stem cells, UT Southwestern Medical Center

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Bold New Alliance Among Houstons Leading Health Care Providers to Transform Care Delivery in the Region Clinical Services, Research and Education Greatly Enhanced by New Collaborations for CHI, St. Lukes, Baylor College of Medicine and Texas Heart Institute HOUSTON (Jan. 7, 2014) Three of the regions leading medical institutions Baylor College of Medicine, CHI St. Lukes Health and the Texas Heart Institute have significantly expanded and enhanced their long-standing educational, clinical and research affiliations in conjunction with Englewood, Colo.-based Catholic Health Initiatives, which sponsors and operates the newly named CHI St. Lukes Health. Catholic Health Initiatives, one of the nations largest health systems, announced today that CHI St. Lukes has partnered with Baylor

Posted by admin on November 26, 2013 Leave a Comment

The city of San Antonio will invest $200,000 in a biotech startup founded to develop new advances in stem-cell technology. City Council voted Thursday to invest in StemBioSys, Inc. through a grant to the San Antonio Economic Development Corporation. The money will be used for stem-cell research, development and manufacturing. StemBioSys, founded in 2010, holds two patents and has three others pending. The company has four employees and will hire at least two more in the next year. The company was formed by Dr. Xiao-Dong Chen, a professor at University of Texas Health Science Center at San Antonio, and Dr. Steven Davis, a San Antonio dermatologist, using licensed stem-cell technology Chen created at the university.

Posted by admin on November 19, 2013 Leave a Comment

Research with mice may someday help people recovering from heart attacks, scientists say New insight into the hearts ability to repair itself could help scientists develop ways to improve recovery after a heart attack, a new study of mice suggests. Researchers found that a signaling pathway called the Hippo pathway normally blocks heart repair in adult mice. When certain signals were removed, the animals hearts were able to regenerate after being damaged. This was because specialized heart cells called cardiomyocytes were able to multiply much better after the signals were removed, an ability that is normally lost in damaged hearts, according to the researchers from the Baylor College of Medicine and the Texas

Posted by admin on October 16, 2013 Leave a Comment

Daria O Brians Science Club Adventures in Time Not currently available on BBC iPlayer Series 2 Episode 2 of 6 Dara O Briain and the team go on a journey through time to discover what it is and how to get more of it. Watch Video Recommend on FacebookTell a friend

Category Body Parts, For the Kids!, Organs, Stem Cells, Texas, Texas Research, Videos Tags BBC, Daria O Brian's Science Club, Doris Taylor, For the Kids!, Helen Czerski, organs, Texas Heart Institute

Posted by admin on September 13, 2013 Leave a Comment

HOUSTON Gov. Rick Perry today announced a $3 million investment through the Texas Emerging Technology Fund (TETF) to create the Center for Cell and Organ Biotechnology in collaboration with the Texas Heart Institute (THI) and Texas A&M University College of Veterinary Medicine & Biomedical Sciences. This center represents another step toward making Texas the forefront of biotechnology for generations to come, Gov. Perry said. The investment is all a part of the culture of creation weve nurtured in Texas, built upon the concept that if you give bright and visionary people the freedom to innovate and pursue their dreams, good things will happen. I could not be prouder that this life-affirming research will be

Posted by admin on June 20, 2013 Leave a Comment

Its a pioneering procedure. Doctors at Austins Heart Hospital are taking a patients own stem cells from bone marrow a few days after a heart attack and injecting those stem cells back into formerly blocked arteries. Dr. Roger Gammon is an Interventional Cardiologist who leads the research team at the hospital. He says, We think those stem cells in particular are most able to recover heart muscle and grow new blood vessels in an area which could save that heart muscle. This trial could be a critical next step in fighting the nations number one killer. Medication and surgery to open blocked arteries have dramatically improved survival rates for people with heart disease. But once

Category Headlines, Heart Attacks, Heart Disease, Heart Failure, Stem Cells, Texas, Texas Research, Videos Tags Austin's Heart Hospital, Bone Marrow, heart attack, Roger Gammon, stem cells

Posted by admin on June 19, 2013 Leave a Comment

Texas Heart Institute One of Many Hospitals Seeing Success in Organ Creation On average, 18 people die each day awaiting an organ donation one person is added to the waiting list for organ transplants every ten minutes. Although nearly 80 people receive an organ transplant per day according to OrganDonor.gov, the gap between donations made and those awaiting organs is devastating for those on the waiting list. There is good news on the horizon for the 100,000-plus people awaiting a transplant, however. Researchers in Texas and across the globe are working on a way to create organs from the patients own body. While 3D printed versions of large organs such as kidneys are

Category Headlines, Heart Disease, Stem Cells, Technology, Texas, Texas Research, Videos, World News Tags 3D printed, Doris Taylor, OrganDonor.gov, Stanford, stem cells, Texas Heart Institute

Posted by admin on May 30, 2013 Leave a Comment

Doctors at the Texas Heart Institute (THI) at St. Lukes Episcopal Hospital (SLEH) announced that they have performed an investigational procedure on six patients in a new FDA-approved clinical trial to evaluate therapy that uses regenerative cells derived from a patients own adipose (body fat) tissue to treat a severe form of heart failure. The trial, known as ATHENA, marks the first such study in the United States using adipose-derived regenerative cells, known as ADRCs, which are harvested using a technology developed by Cytori Therapeutics, a biotechnology company that specializes in cell therapies. Previous studies in Europe have shown the safety and feasibility of the therapy. We have found that body fat tissue is a

Category Adipose, Headlines, Heart Disease, Heart Failure, Stem Cells, Technology, Texas, Texas Research Tags adipose, ADRC, Cytori Therapeutics, Fat-Derived Regenerative Cells, heart failure, James T. Willerson, Texas Heart Institute

Posted by admin on April 30, 2013 Leave a Comment

Texas Heart Institute not concerned about changes at St. Lukes A spokesman for Texas Heart Institute said the center does not have any ongoing research that would be in direct conflict with the faith-based medical care of Denver-based Catholic Health Initiatives. The St. Lukes Episcopal Health System said April 19 it decided to sell to CHI, the nations second-largest faith-based health system. Shortly after, concerns arose about whether the Catholic provider would eliminate any procedures currently offered at St. Lukes. The Texas Heart Institute is affiliated with but not owned or governed by St. Lukes, though it is housed within St. Lukes Episcopal Hospital in the Texas Medical Center. CHI issued a statement April 26

Category Headlines, Heart Disease, Heart Failure, Stem Cells, Technology, Texas, Texas Research, Vascular Disease, World News Tags Catholic Health Initiatives, CHI, Denton Cooley, St. Luke's Episcopal Hospital, Texas Heart Institute

Posted by admin on April 25, 2013 Leave a Comment

Latest advances in treatment for Alzheimers,traumatic brain injury and stroke to be presented at symposium AUSTIN, Texas (April 24, 2012) Some of the countrys leading practitioners will discuss the cutting-edge treatments and imaging techniques being developed to treat Alzheimers, traumatic brain injury and stroke at a symposium on May 1 in Austin. Collaborating for Cures: Research, Rehabilitation & Treatment for Alzheimers, Brain Injury & Stroke will feature presentations on The Promise of Stem Cells; Current treatment of closed head injury, Disorders of consciousness, Imaging in dementia, Drug screening for degeneration, Pain syndrome after stoke, Emerging therapeutics in ischemic stroke and Neurorecovery vs neurorehabilitation as well as provide a forum for leading scientists in the

Category Alzheimer's, Headlines, Preclinical, Stroke, Texas, Texas Research Tags Alzheimers, brain injury, CORE Health Care, Core Health Foundation, Moss Rehabilitation & Research Institute, Nantz National Alzheimers Center, NeuroTexas Institute, Reliant Austin Rehabilitation Hospital, Seton Brain & Spine Institute, St. Davids HealthCare, Stroke, Texans for Stem Cell Research, Texas Cures Education Foundation, TIRR Memorial Hermann, UT Southwestern

Posted by admin on March 1, 2013 Leave a Comment

Reprogramming Adult Cells to Stem Cells Works Better with One Gene Turned Off The removal of a genetic roadblock could improve the efficiency of converting adult cells into stem cells by 10 to 30 times, report scientists from The Methodist Hospital Research Institute and two other institutions in the latest issue of Cell. The discovery six years ago that scientists can convert adult cells into inducible pluripotent stem cells, or iPSCs, bolstered the dream that a patients own cells might be reprogrammed to make patient-specific iPSCs for regenerative medicine, modeling human diseases in petri dishes, and drug screening, said Rongfu Wang, Ph.D., Principal Investigator and Director of the Center for Inflammation and Epigenetics. But reprogramming

Category Drug Discovery, Headlines, Regenerative Medicine, Stem Cells, Texas, Texas Research Tags Center for Inflammation and Epigenetics, drug screening, epigenetic, inducible pluripotent stem cells, Regenerative Medicine, Rongfu Wang, The Methodist Hospital Research Institute

Posted by admin on February 22, 2013 Leave a Comment

A University of Texas spinoff company has pulled in $2 million to test a new technique for culturing non-embryonic stem cells. According to a regulatory filing, StemBioSys raised at least $2 million of a $3.5 million equity offering. A company representative was not available to elaborate, but CEO Dr. Steven Davis told the San Antonio Business Journal last year when the company began raising the round that it would fund research projects to validate the quality of the stem cells generated by the companys technology. StemBioSys is developing XC-marrow ECM, a propriety three-dimensional culture for growing mesenchymal stem cells from bone marrow, adipose tissue and umbilical cord blood. These immature cells have multiple potential uses

Posted by admin on February 7, 2013 Leave a Comment

Every week, it seems, theres a new breakthrough in 3-D printing that promises us the ability to (eventually) fabricate some new thing in one of those glass-walled wonder boxes. Such things have included everything from spare parts for the International Space Station above to the beef on our dinner plates to the organs inside our bodies. Although this last idea of fabricating body parts may seem the most fanciful, a team of scientists is reporting a breakthrough in 3-D printing using human embryonic stem cells that could purportedly lead to life-like bioengineered tissue and, eventually, artificial organs tailor-made for specific patients. Researchers have been able to engineer tissue samples in then past by combining artificial

Posted by admin on January 27, 2013 Leave a Comment

Doris Taylor and her team are building new organs, hoping to reverse disease, maybe even the aging process By Maggie Galehouse | January 23, 2013 It sounds like science fiction, but it is isnt. On the ninth floor of the Texas Heart Institutes Denton Cooley building, Doris Taylor and her team are building human hearts, with help from pigs and stem cells. We think a pig heart is a perfect scaffold for a human heart, based on its structure and size, says Taylor, a passionate scientist with a Ph.D. in pharmacology. One recent morning, a pig heart hung suspended in a clear homemade tank in the lab built for Taylor and her team. Filled with

Category Headlines, Heart Disease, Heart Failure, Regenerative Medicine, Stem Cells, Texas, Texas Research Tags Doris Taylor, Houston Chronicle, Jame T. Willerson, Maggie Galehouse, Regenerative Medicine, stem cells, Texas Heart Insitute

Posted by admin on January 21, 2013 Leave a Comment

After a nationwide competition, Texas Heart Institute at St. Lukes Episcopal Hospital has been chosen as the Biorepository Core Lab for the National Heart, Lung and Blood Institutes network of cardiac stem cell research centers. The seven centers, collectively known as the Cardiovascular Cell Therapy Research Network, are home to a network of physicians, scientists and support staff who work together to study stem-cell therapy for treating heart disease. The goals of the network are to complete research studies that will potentially lead to more effective treatments for patients with cardiovascular disease, and to share knowledge quickly with the health care community. Read Full Story Recommend on FacebookTell a friend

Posted by admin on January 8, 2013 Leave a Comment

Scar Tissue In Damaged Hearts Reprogrammed By Gene Therapy Into Healthy Heart Muscle A cocktail of three specific genes can reprogram cells in the scars caused by heart attacks into functioning muscle cells, and the addition of a gene that stimulates the growth of blood vessels enhances that effect, said researchers from Weill Cornell Medical College, Baylor College of Medicine and Stony Brook University Medical Center in a report that appears online in the Journal of the American Heart Association. The idea of reprogramming scar tissue in the heart into functioning heart muscle was exciting, said Dr. Todd K. Rosengart, chair of the Michael E. DeBakey Department of Surgery at BCM and the reports corresponding

Posted by admin on January 4, 2013 Leave a Comment

The Alliance for Regenerative Medicine (ARM), the international organization representing the interests of the regenerative medicine community, today announced that 18 ARM members will be presenting at the Biotech Showcase 2013 meeting in San Francisco next week. Featuring company presentations by leading organizations in the industry, Biotech Showcase, produced by EBD Group and Demy-Colton Life Science Advisors, has emerged as a high profile forum for mid-, small- and micro-cap and private companies seeking access to the investor community and potential collaborators. Collectively, the ARM members presenting will showcase the wide scope of progress that is taking place in the regenerative medicine and cell therapy field. (Press Release) Recommend on FacebookTell a friend

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Texas Research : Stem Cell Cite

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