Stem Cell Therapy for Osteoarthritis

New treatments and advances in research are giving new hope to people affected by Osteoarthritis pain and symptoms. Stem Cell Research Centre provides stem cell therapy for Osteoarthritis to help those with unmet clinical needs achieve optimum health and better quality of life.

Stem cell therapy for Osteoarthritis is being studied for efficacy in improving the complications in patients through the use of their own stem cells. These procedures may help patients who dont respond to typical drug treatment, want to reduce their reliance on medication, or are looking to try stem cell therapy before starting drug treatment.

To learn more about becoming a patient and receiving stem cell therapy for Osteoarthritis through Stem Cell Research Centre, please contact one of our patient advocates at (800) 609-7795 or fill out the contact form on this page.Below are some frequently asked questions about stem cell treatment for Osteoarthritis.

The majority of complications in Osteoarthritis patients are related to the deterioration of cartilage that cushions the ends of bones in your joints. Cartilage is a firm, slippery tissue that permits nearly frictionless joint motion. In Osteoarthritis, this surface become rough. Eventually, if the cartilage wears down completely, patients will be left with bone rubbing on bone.

Stem cell treatment provided by Stem Cell Research Centre is designed to target these areas within the joints to help with the creation of new cartilage cells. Mesenchymal stem cells are multipotent and have the ability to differentiate into cartilage called (chondrytes). The goal of each stem cell treatment is to inject the stem cells into the joint to create cartilage (chondryte cells). Stem cells are a natural anti-inflammatories which can assist with Osteoarthritis pain and swelling in the joint area.

Stem cells are the basic building blocks of human tissue and have the ability to repair, rebuild, and rejuvenate tissues in the body. When a disease or injury strikes, stem cells respond to specific signals and set about to facilitate the healing process by differentiating into specialized cells required for the bodys repair.

There are four known types of stem cells which include:

Stem Cell Research Centre provides autologous adult stem cells (from fat tissue) where the stem cells come from the person receiving treatment.

Stem Cell Research Centre provides autologous adult adipose-derived stem cells (from fat tissue) where the stem cells come from the person receiving treatment.

We tap into our bodys stem cell reserve daily to repair and replace damaged or diseased tissue. When the bodys reserve is limited and as it becomes depleted, the regenerative power of our body decreases and we succumb to disease and injury.

Three sources of stem cells from a patients body are used clinically which include adipose tissue (fat), bone marrow and peripheral blood.

Performed by Board Certified Physicians, dormant stem cells are extracted from the patients adipose tissue (fat) through a minimally invasive mini-liposuction procedure with little to no downtime.

During the liposuction procedure, a small area (typically the abdomen) is numbed with an anesthetic and patients receive mild to moderate sedation. Next, the extracted dormant stem cells are isolated from the fat and activated, and then comfortably infused back into the patient intravenously (IV) and via other directly targeted methods of administration. The out-patient procedure takes approximately four to five hours.

Stem Cell Research Centre provides multiple administration methods for Osteoarthritis patients to best target the disease related conditions and symptoms which include:

Since each condition and patient are unique, there is no guarantee of what results will be achieved or how quickly they may be observed. According to patient feedback, many patients report results in one to three months, however, it may take as long as six to nine months. Individuals interested in stem cell therapy are urged to consult with their physician before choosing investigational autologous adipose-derived stem cell therapy as a treatment option.

In order to determine if you are a good candidate for adult stem cell treatment, you will need to complete a medical history form which will be provided by your Stem Cell Research Centre Patient Advocate. Once you complete and submit your medical history form, our medical team will review your records and determine if you are a qualified candidate for adult stem cell therapy.

Stem Cell Research Centre team members are here to help assist and guide you through the patient process.

Patients travel to Stem Cell Research Centre treatment center located in San Diego, California for stem cell treatment from all over the United States, Canada and around the globe. Treatment will consist of one visit lasting a total of three days. The therapy is minimally invasive and there is little to no down time. Majority of patients fly home the day after treatment.

We provide stem cell therapy for a wide variety of diseases and conditions for which traditional treatment offers less than optimal options. Some conditions include Multiple Sclerosis, Parkinson's Disease, Rheumatoid Arthritis, Osteoarthritis and Chronic Obstructive Pulmonary Disease (COPD).

The side effects of the mini-liposuction procedure are minimal and may include but are not limited to: minor swelling, bruising and redness at the procedure site, minor fever, headache, or nausea. However, these side effects typically last no longer than 24 hours and are experienced mostly by people with sensitivity to mild anesthesia. No long-term negative side effects or risks have been reported.

The side effects of adipose-derived stem cell therapy are minimal and may include but are not limited to: infection, minor bleeding at the treatment sites and localized pain. However, these side effects typically last no longer than 24 hours. No long-term negative side effects or risks have been reported.

Stem Cell Research Centre provides adult stem cell treatment with mesenchymal stem cells which come from the person receiving treatment. Embryonic stem cells are typically associated with ethical and political controversies.

Stem cell treatment is not FDA approved.

Stem cell for arthritis treatment is not covered by health insurance at this time. The cost for standard preoperative labs are included. Additional specific labs may be requested at the patients expense.

Osteoarthritis, or degenerative joint disease, is the most common type of arthritis. It is caused by the degradation of a joints cartilage. Cartilage is a firm, rubbery material that covers and cushions the ends of bones in normal joints. Its main function is to reduce friction in the joints and serve as an intermediary or cushion.

Over time, the cartilage may wear away in some areas, greatly decreasing its ability to act as a shock absorber. As the cartilage wears away, tendons and ligaments stretch, causing pain. In advanced cases, the bones could rub against each other, causing even more pain and loss of movement.

Osteoarthritis is very common in middle-aged and older people, and its symptoms can range from very mild to very severe. The disorder most often affects hands and weight-bearing joints such as knees, hips, feet and shoulders, but can affect almost any joint in the body.

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FAQs - Stem Cell Therapy for Osteoarthritis | SCRC

What are stem cells?

Stem cells are the basic building blocks of human tissue and have the ability to repair, rebuild, and rejuvenate tissues in the body. When a disease or injury strikes, stem cells respond to specific signals and set about to facilitate the healing process by stimulating your own body to repair itself.

Stem cells that come from perinatal tissue(healthy post-natal C-sections) have distinct functional properties including immunomodulation and anti-inflammation which support the repair and regeneration of damaged tissue associated with disease and injury.

There are four known types of stem cells which include:

We provide allogeneic regenerative cytokines and mesenchymal stem cells from health post-natal C-sections.

We tap into our bodys stem cell reserve daily to repair and replace damaged or diseased tissue. When the bodys reserve is limited and as it becomes depleted, the regenerative power of our body decreases and we succumb to disease and injury.

Three sources of stem cells from a patients body are used clinically which include adipose tissue (fat), bone marrow and umbilical cord matrix(Whartons Jelly).

We provide stem cell therapy for a wide variety of musculoskeletal conditions for which traditional treatment offers less than optimal options. Some conditions include Osteoarthritis, Bursitis, Plantar Fasciitis and Degenerative Disc Disease

Since each condition and patient are unique, there is no guarantee of what results will be achieved or how quickly they may be observed. According to patient feedback, many patients report results in one to three months, however, it may take as long as six to nine months. Individuals interested in stem cell therapy are urged to consult with their physician before choosing investigational allogeneic umbilical cord derived regenerative medicine allografts as a treatment option.

In order to determine if you are a good candidate for a regenerative medicine treatment, you will need to complete a medical history form which will be provided by our patient advocate team. Once you complete and submit your medical history form, our medical team will review your records and determine if you are a qualified candidate for a regenerative medicine therapy.

The side effects of intra-articular injection of a regenerative medicine allograft are minimal and may include but are not limited to: infection, minor bleeding at the treatment sites and localized pain. However, these side effects typically last no longer than 24 hours.

We provide regenerative medicine allografts from healthy post-natal C-section births that provide regenerative factors and mesenchymal stem cells. Embryonic stem cells are typically associated with ethical concerns. We do not offer embryonic stem cells.

Our regenerative medicine allografts are regulated as human cell and tissue transplants, similar to skin and bone. As structural human cell and tissue products regulated under FDA CFR 1271 Part 361, our allografts do not require FDA approval, rather we are strictly regulated to prevent the spread of communicable diseases and to maintain the structural integrity of the allografts as theyre harvested from umbilical cords and transferred for musculoskeletal cushioning, protection and supplementation. These regenerative allografts are FDA regulated rather than FDA approved. The FDA is a regulatory oversight body and doesnt exercise legal authority. If an FDA regulated tissue transplant or therapy is noted as non-compliant and not corrected according to FDA guidelines, the FDA may refer a significant public health risk to the Department of Justice or a state attorney general.

Stem cell treatment is not covered by health insurance at this time.

Although stem cells are found throughout our bodies, mesenchymal stem cells can only be harvested for native (non-cultured) use from adipose, bone marrow and umbilical cord matrix. The term amniotic stem cells is an oxymoron in that amniotic fluid and matrix products dont contain stem cells. They do however contain unique cytokines and other growth factors.

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The Stem Cell Procedure

Optimal Health Medical, LLC uses adult autologous stem cells, meaning that they are derived and taken from your own body, which avoids the possibility of rejection. A simple in-office procedure a called a bone marrow aspiration is performed to obtain your own stem cells.

HOW IS BONE MARROW ASPIRATION PERFORMED?

Bone marrow is extracted from the back of a patients pelvis called the posterior iliac crest.

The doctor will inject a local anesthetic (numbing agent), to prevent discomfort and pain. Bone Marrow aspiration involves one small incision in the skin to introduce the bone marrow needle for aspiration. You may experience some discomfort during the procedure, but it is brief, and if needed more local anesthesia will be provided.

HOW LONG IS THE PROCEDURE?

The actual extraction takes just a couple of 2 minutes. The full procedure and visit will take up to a couple of hours. During that time the handling of the bone marrow sample will include separating the red blood cells, and placing the sample in a centrifuge for its final preparation for injection back into the body.

Utilizing the most advanced technique for stem cell injection, the doctor will perform what is called a Guided Stem Cell Injection. Guided injection stem cell treatments are done by the doctor using a portable ultrasound machine, positioned to allow the doctor to see the needle as he guides it to the area to be injected.

IS THE PROCEDURE SAFE?

Bone marrow aspirations are safe when properly performed in a sterile environment. Complications are rare but can include:

The risks of a bone marrow aspirate include the following: pain or temporary discomfort and/or bruise at the site of the puncture. Post-procedure treatment guidelines will be provided in the initial consultation.

HOW LONG IS THE RECOVERY TIME?

Most patients are able to return to basic daily activities in 3 days but some pain may be felt at the aspiration site for up to 1 week. Return to exercise or sports or which place on the joint may take several weeks, and guided by the doctor on an individualized basis.

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Stem Cell Therapy has been around for quite some time, but due to high cost it was primarily used for recovery in athletes and the financial elite. However, with the progression of science and knowledge, stem cell therapy has become much more widely used and financially attainable.

Tampa Rejuvenation is the first in Tampa Bay to utilize the benefits of stem cell therapy for the purpose of anti-aging and sexual performance. We realize as our patients age, their bodies no longer have the regenerative properties to attain the desired results from using their growth factors alone as with our PRP, or Plasma Rich Platelet, therapy. Although many patients will still yield improvement with the PRP alone, the magnitude of cytokines and growth factors in your blood as you age will deplete with age. By implementing stem cell therapy, the number of growth factors are exponential allowing our bodies to regenerate on a magnitude that is otherwise unattainable with some results lasting for 3-5 years.

Stem Cell Therapy can be used to restore vitality to the skin, encourage the growth of hair, and even restore sexual performance and pleasure.

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Stem Cell Therapy for Anti-Aging and Sexual Performance ...

Stem cell therapy is an exciting area of research that holds tremendous potential for helping chronic pain patients reduce their pain. Rapid advances in this field of medicine are buoying doctors and patients hopes that the exciting therapy could change lives. Advances are being made nearly every day, and as scientists further understand the nature of these cells, even more uses for them are becoming known. If youve ever wondered about how stem cell therapy for pain could help you, these 15 questions delve into how this therapy works and who it could be used for.

Science has a strong interest in stem cells because of their renewing properties and the ability of these cells to develop into any type of tissue in the body of the organism. Researchers believe that they have the potential for immeasurable clinical uses in health. Research is advancing many stem cell based therapies for people who suffer from diseases such as:

Mayo Clinic explains how this therapy works:

Stem cell therapy, also known as regenerative medicine, promotes the reparative response of diseased, dysfunctional or injured tissue using stem cells or their derivativesResearchers grow stem cells in a lab. These stem cells are manipulated to specialize into specific types of cells, such as heart muscle cells, blood cells or nerve cells. The specialized cells can then be implanted into a person.

Stem cell therapy is actually a type of treatment within the larger umbrella of regenerative medicine. Our longer post on regenerative medicine discusses the types of treatments available, including stem cell therapy and platelet-rich plasma injections.

Stem cells are essentially blank canvases that can transform into any type of cell in the human body. Specialized cells like bone cells, liver cells, and heart cells begin as stem cells. The process of the cells transforming from blank slates into specialized cells is called differentiation.

Stem cell therapy is the process of injecting these cells into damaged areas of the body, such as arthritic knees or shoulders. The stem cells then differentiate into damaged tissue, helping to regenerate the entire area.

There are two different types of natural stem cells and one that is genetically reprogrammed within the laboratory. Embryonic stem cells are the most immature and are found within the early stages of a growing embryo, usually after it has been left to develop five to six days. After the egg and sperm have united, the fertilized egg divides and creates stem cells that differentiate into the specialized cells the body requires to function. Many techniques using stem cells for pain therapies no longer rely on these types of stem cells.

The second type of stem cell, found naturally in organisms, is adult stem cells. These are present in developed tissue, such as muscle, skin, bone, brain, and blood. Also called tissue stem cells, they can self-renew and generate one specialized cell type. Under normal circumstances these tissue stem cells, or adult stem cells, will generate the type of cells that make up the organ in which they reside. These cells are used by the body to divide and repair injured areas or regenerate into specialized cells to replace the ones that are dead or damaged.

The third type of stem cells, which are genetically reprogrammed in the laboratory, are induced pluripotent stem cells. After years of stem cell research and development, it was discovered that artificially triggering certain genetic components would prompt different cells to become pluripotent stem cells, which were similar in nature to embryonic stem cells. This helps avoid ethical concerns associated with using human embryonic tissue for research and regenerative medicine.

The following video from an Arizona pain doctor goes into detail about how stem cell therapy for pain works.

There are twomajor types of stem cells: those harvested from adults and those harvested from embryonic tissues.

However, there are other ways to retrieve stem cells that reduce the use of embryonic stem cells, including:

As the Euro Stem Cell organization reports, some of these types of stem cells are more effective than others.

One source of stem cells is human embryos. These cells are called pluripotent stem cells, and theyre very useful to researchers because they can be multiplied indefinitely in the laboratory. Although these cells are often cultivated from embryos that are just a few days old, they can also be taken from fetal tissue thats older than eight weeks, according to the National Institutes of Health (NIH).

The majority of therapeutic stem cells come from adults. Even though embryos are the richest source of stem cells, humans of all ages have stem cells. Stem cells give adults the ability to replace damaged tissue, heal wounds, and grow hair.The patients own adult stem cells are extracted, purified, concentrated, and then injected into the damaged tissue. This process is usually non-surgical and the individual has very little recovery time. Most patients report only some soreness around the site of the injection. Sometimes there is also slight bruising. There have been no reports of serious side effects from treatments using stem cell therapy.

Newer research has given scientists the ability to reprogram specialized adult cells so they essentially return to their original stem cell state. These reprogrammed cells are known as induced pluripotent stem cells. Although this ability exists, scientists arent sure how or if these artificially created stem cells behave differently than other types.

Despite these unknowns, the reprogrammed stem cells are already being used in the development of medicines and helping scientists learn more about specific types of diseases, according to NIH.

Stem cells have many uses, and the full spectrum of their application isnt yet known. One way stem cells are helping researchers is by illuminating the inner workings of various diseases. Stem cells offer scientists the ability to model human disease progression in a laboratory setting.

This is exciting because many studies rely on animals with similar, but not exact, biology to humans. The more scientists can understand about human-specific disease progression, the greater insight they have regarding potential treatments.

For example, one of the earliest uses for stem cells were bone marrow transplants, used to help patients with leukemia or sickle cell anemia heal. This treatment has been used for more than 40 years. In addition, stem cell therapy may be used to treat:

The application of most interest to chronicpatients is likely the emerging field of regenerative medicine, which is the science of helping tissues regenerate. This field examines the potential of stem cells to repair damaged tissue and heal areas of the body bone and potentially organs, too affected by arthritis, diabetes, spinal cord injuries, nerve damage, Parkinsons disease, and more.

Exciting research has also uncovered the potential for stem cells to expand the number of lungs available for transplant. A portion of lungs available for transplant arent used because they become damaged. However, research from the American Physiological Society has found stem cells could help repair the organs and prepare them to save lives.

Other recent researchstories include:

For many of the studies underway, time is needed to fully examine the benefits and potential dangers of this treatment. Another obstacle is obtaining specific types of adult stem cells. Theyre difficult to grow in the laboratory, making it hard to produce the large numbers available for research.

Another potential issue with donor stem cells is the possibility of rejection. The immune system of the recipient could reject the cells, essentially making it difficult for the treatment to work as intended and causing ancillary problems.

Finally, since this is such a new treatment area, some government agencies are calling for more oversight of its use. Others are pushing back, claiming that stem cell therapy provides a new area of treatment for patients who have exhausted all other options.

That being said, even though there are complications and roadblocks to its use, the benefits of stem cell therapy could be huge. As the American Academy of Anti-Aging Medicine notes:

[A]n analysis of the potential benefits of stem cells based therapies indicates that 128 million people in the United States alone may benefit with the largest impact on patients with Cardiovascular disorders (5.5 million), autoimmune disorders (35 million) and diabetes (16 million US patients and more than 217 million worldwide).

Californias Stem Cell Agency gives a great overview of this process, noting:

In order to be approved by the FDA for use in human trials, stem cells must be grown in good manufacturing practice (GMP) conditions. Under GMP standards, a cell line has to be manufactured so that each group of cells is grown in an identical, repeatable, sterile environment. This ensures that each batch of cells has the same properties, and each person getting a stem cell therapy gets an equivalent treatment. Although the FDA hasnt yet issued guidelines for how pluripotent stem cells need to meet GMP standards, achieving this level of consistency could mean knowing the exact identity and quantity of every component involved in growing the cells.

Stem cell therapy is being studied for a number of chronic pain conditions, especiallypain in the:

Stem cell therapy for pain could help reduce the inflammation that results in chronic pain, or it could help to heal regenerative conditions that lead to pain, such as arthritis.

Using stem cell therapy for knee pain is one of the leading areas of research. Stem cell therapy for knees can be provided as stem cell injections or as blood platelet treatments from the body itself (another form of regenerative medicine).These two treatments may help relieve pain associated with:

The leading researchers on stem cell therapy for knee pain claim that it can help patients avoid surgery, with its associated costs and risks.

Since stem cell therapy promises to treat a number of conditions related to degenerative conditions, like arthritis and tendonitis, stem cell therapy may present a great treat option for hip pain related to these causes.

The National Multiple Sclerosis Society is leading the efforts in research, but currently reports the following:

At present, there are no approved stem cell therapies for MS. Larger, longer-term, controlled studies are needed to determine the safety and effectiveness of using stem cells to treat MS. When the results of these and subsequent clinical trials are available, it should be possible to determine what the optimal cells, delivery methods, safety and actual effectiveness of these current experimental therapies might be for different people with MS.

Potentially. One of our sister clinics, Arizona Pain, is participating in a study evaluating the potential of stem cells to reduce back pain related to degenerative disc disease. This progressive condition sometimes results from injury, but other times has no clear cause.

The study is exciting because it involves stem cells harvested from the bone marrow of healthy, young adults, and therefore itdoesnt come with the ethical concerns of embryonic stem cells. So far, the results have been very positive, and a significant number of people who received stem cells for their back pain have experienced reduced discomfort and improved quality of life.

This study is currently in Phase III, which is the phase immediately preceding potential FDA approval. This means it could soon be available to many more patients and potentially covered by insurance, although each insurance companys coverage policy varies.

Absolutely, and the research into this area is very promising. In fact, scientists have recently uncovered the specific type of stem cell most likely to reduce arthritis pain. Theyre special cells that are specifically able to rebuild tissue, bone, and cartilage, potentially offering much relief to osteoarthritis patients.

What other questions do you have regarding stem cell therapy for pain? If youre ready to learn more about using stem cell therapy to treatyour pain, click the button below to find a pain specialist in your area.

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15 Stem Cell Therapy For Pain Questions, Answered