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Research Paper Transhumanism – Middlebury College

Posted: May 4, 2019 at 2:53 am

Sophie Robart

Professor Tom Beyer

FYSE 1286

11 November 2013

What is a Society of Posthumans?

Transhumanism is a field of philosophy that aspires to further the abilities of humans by utilizing opportunities of science and technology to enhance human life. Transhumanists see the human condition today as less than what it could or should be, and strive for society to become full of posthumans. These philosophers believe that the next few generations will belong to those who want to advance human life conditions, rather than act skeptically towards the idea of change. These Transhumanists hope that this change in society will stem from a generation that will have been raised and assimilated with the ideas of Transhumanism. While for Transhumanists the concept of changing mankind in order to eliminate disease and enhance intellectual capacity is solely to better the world, their concept of change has sparked uproar among bio-conservatives throughout the world. These bio-conservatives, religious ethicists and philosophical ethicists, agree on two major principles regarding Transhumanism: that boundaries were set to keep humans as humans, and to try and pass those boundaries is greedy.

Max More, one philosopher and futurist, defines Transhumanism as a class of philosophies of life that seek the continuation and acceleration of the evolution of intelligent life beyond its currently human form and human limitations by means of science and technology, guided by life-promoting principles and values.[1] Max More, the Chief Executive Officer of Alcor Life Extension Foundation, a world leading company in cryonics, proposed this definition of transhumanism in his essay: Transhumanism: Toward a Futurist Philosophy. He also proclaims that we have achieved two of the three alchemists dreams: We have transmuted the elements and learned to fly. Immortality is next.

Three names, including Max More, stand out as leaders and innovators within the Transhumanist and post human movement. Fereidoun M. Esfandiary, more commonly known as FM-2030, distinguished himself inside of Transhumanism with Are You a Transhuman.[2] When asked about his name and identification, Esfandiary explained that In 2030 we will be ageless and everyone will have an excellent chance to live forever. 2030 is a dream and a goal. FM-2030 died in 2000 and was placed in cryonic suspension at the Alcor Life Extension Foundation. Natasha Vita-More, often considered the first female philosopher of transhumanism, founded the Transhumanist Arts and Extropic Arts Movement in 1982: designed to provide insight into the future directions of art and creativity of the 21st Century as well as a brief history of Transhumanity, Transhumanist Arts, and Extropic Art.

The leaders of the Transhumanism movement claim that the idea and goal of enhancement are not new to the twenty-first centurythere are many texts written about the ideas of enhancement from before the 1800s. The French philosopher, Marquis de Condorcet, wrote in 1794 that no bounds have been fixed to the improvement of facultiesthe perfectibility of man is unlimited (Encyclopedia of Bioethics, p.2517). Kevin Warwicks claims in 2000 that, [he] was born a human. But this was an accident of fatea condition merely of time and place (Encyclopedia of Bioethics 2518).

Current Transhumanists express their beliefs in multiple different ways. Some people do not openly live a life supporting Transhumanism due to the social stigma that may be associated with the movement, but they do their part. Others actively fund and investigate the science that might eventually lead to a reality full of posthumans. One of the major goals of that Transhumanists is to advance the human nervous system to enhance the capability of intelligence, and subsequently strengthen the defense system against disease. Through the processes of nanotechnology, biotechnology, and cognitive science, Transhumanist scientists are attempting to further life span, eradicate diseases, and enhance intelligence.

Nanotechnology is a process in which scientists manipulate matter on a molecular level. A new piece of technology called the Nano-Bio Processor mimics responses of the human body and aids the development of corresponding treatments. Professor Nick Bostrom, director of the Future of Humanity Institute at Oxford University, believes that this technology offers the potential to alleviate human suffering. Professor Bostrom claims that the Nano-Bio Processor will improve human condition, and that humans have a fundamental right to develop this technology or many preventable deaths might occur as a result of not developing NBIC.

Scientists are also using biotechnology to investigate and further the Transhumanism movement. Biotechnology is the direct or indirect use of living organisms, or parts or products of living organisms, in their natural or modified forms. Biotechnology is one of the processes more apparent in society, which bio-conservatives happily feel limits some of the risky actions by lend[ing] credence to visions of transcendence and transformation (Lilley Part 1). Meanwhile, biotechnology is a technology that is backed by well financed research programs while corporations and nation states compete fiercely over them (Lilley Part 1). One of the current uses of biotechnology that Transhumanists use is DNA and related genetic structure manipulation (Lilley Part 1). Currently, stem cells are being coaxed from embryos, placentas, and skin and are being primed to promote regeneration (Lilley Part 1). Transhumanists see the completion of the rough draft of the human genome project, published in 2000, as a scientific milestone, and research is now focused on decoding the functions and interactions of all these different genes (Humanity+, Answer 23).

Other Transhumanist scientists are studying cognitive sciencehow information is processed in different ways including perception, language, and emotion. It is apparent that scientists hope this research will lead to the elimination of mental diseases, as well as a faster processing speed. These different technologies are quite controversial; Nancy Campbell claims that these different technologies in their development, deployment, and effects are unevenly distributed, differential, and more likely to be socially unjust than not (Lilley Part 1).

Transhumanists often argue with bio-conservatives about the ethics of these practices. Transhumanists maintain that changing the genetics and human practices will not change the humanity of people:

[we] read and write; we wear clothes; we live in cities; we earn money and buy food from the supermarket; we call people on the telephone, watch television, read newspapers, drive cars, file taxes, vote in national elections; women give birth in hospitals; life-expectancy is three times longer than in the Pleistocene[3]. (Bostrom Ethics)

Bostrom, a prominent Transhumanist, explains in the quote above that nothing about everyday life will change due to the changes that Transhumanists bring about. This idea that nothing will change is hard for bio-conservatives to understand because of the fear of unfair advantages that certain citizens will have over one another.

Transhumanists understand that bio-conservatives argue that these actions will change the dignity of moral status, as well as the quality of being worthy and honorable. In Stephen Lilleys book Transhumanism and Society, he claims that the difference in a transhumanist definition might be man remaining man, but transcending himself, by realizing new possibilities of and for his human nature (Lilley Part 2). Lilley supplements the argument for Transhumanism by claiming that, science can contribute greatly to making the world and mankind more human (Lilley Part 2). While there is a line that bio-conservatives feel must not be crossed, because that line is not specifically defined, transhumanists often take this uncertainty into consideration when starting a new type of research (Chadwick 32).

Bio-conservatives believe in two major theories: there are some boundaries that keep humans the way they were made; and to try and pass these boundaries is greedy. One theorist claims that, to bring about such radical changes in humankindcan only be described as the death of the species(Goffi 8). They also believe that while medicine can be used for legitimate or illegitimate aims (Goffi 9), to enhance human life is an illegitimate use of medicine. Even Professor Goffi, however, understands that it is difficult to draw a sharp line between therapeutic and enhancing procedures (Goffi 10). Many theorists agree with M. Sandel that, although more health is better than less, at least within a certain range, it is not the kind of good than that can be maximized (Goffi 10). Ruth Chadwick, a distinguished research professor at Cardiff School of English, Communication, and Philosophy, claims that if intervention restores a person species-typical normal functioning it falls within the therapy category; otherwise it counts as enhancement (Chadwick 28). Most bio-conservatives believe that human enhancement will eventually dehumanize (Bostrom 2) people. Leon Kass, a prominent bio-conservative, claims that while biotechnology can produce better children, superior performance, ageless bodies, and happy souls, it might eventually be used as a substitute for virtue, hard work, study, or love in order to fulfill our deepest human desires. Overall, bio-conservatives believe that people have a common genetic endowmentand this implies, of course, a common set of genetic limitationsthat they have a common nature and a common set of rights (Goffi 11). Stephen Lilley warns against transgression, or a point of no return from which humanity will suffer a most grievous, irretrievable loss (Lilley Part 2).

While Transhumanists believe that they are advancing humans to a better point in life, one also might claim that advancing beyond a point can become dangerous to society. Paul Ramsey, author of Fabricated Man: The Ethics of Genetic Control, explains in his book that techno-theologians (Goffi 8) and supporters of neo-eugenics (Goffi 9) are willing to manipulate genetics, and reconstruct mankind, yet through this process they are subsequently putting the humanity of man (Goffi 9) at stake. Alan Padgett has a pessimistic view on this movement as well, claiming:

The dream of a happy and harmonious techno-secular future is based on false hopes in infinite energy, infinite human potential, infinite human progress, and complete human good will. Such a techno-secular dream, even if it comes about, will self-destruct after a few centuries, inevitably smashing on the rocks of our finitude and sin. (Lilley, Part 2)

Paul Ramsey explains that he sees transhumanist dreams as well-meaning but all the more dangerous attempt to raise human beings above their own condition. Both George Annas, chair of Bioethics and Human Rights at the Boston University School of Public Health, and Rosario Isasi, a health and human rights attorney, understand and explain that human cloning and genetic modification are both considered crimes against humanity (Bostrom, Ethics). Some scientists even argue that this genetic manipulation will cause a GATTACA-like society, or even the emergence of old fashioned eugenics (Goffi 11).

Not only do people criticize Transhumanism because of its threats to science and humanity, but there are also many religious objections that people find with the transhumanist movement. John Jefferson Davis, a Professor of Systematic Theology and Christian Ethics at Gordon-Conwell Theological Seminary, claims that, all of Gods creation, including the human body, is good (Gen. 1:31; Tim. 4:4) and as such is worth of care and respect (Lilley Part 2). Often Christians disapprove of Transhumanism because of the stance that most transhumanists take on cloning. Ironically, Transhumanism itself has been classified as a religion, and some of the rhetoric is often compared to Christian apologetics.

Transhumanism is a larger part of the media than most people usually notice. Gattaca, the 1997 film staring Ethan Hawke and Jude Law, is a movie, based in a time where eugenics are common, about a genetically inferior man who assumes the identity of a superior one in order to pursue his lifelong dream of space travel. This movie includes genetic manipulation, genetic discrimination, and unfair advantages due to these manipulations. This movie is a prime example of bio-conservatives fear for human society. Another example of transhumanism in the media is Dan Browns 2013 novel Inferno. This trilling fast pace novel incorporates the Zobrist, an active Transhumanist, who threatens an unknown plague upon the world. Finally, I am Legend is another movie with transhumanist values etched into it. A genetically engineered vaccine is created and distributed to people in order to cure cancer, and ends up spreading through the air and killing 90% of the population. This movie then turns into a post-apocalyptic science fiction horror film, in which the 588 million survivors become Darkseerers that prey on people immune to the virus. Clearly this movie shows some of the issues that bio-conservatives fearthe worry of creating viruses that manipulate human genes to a point of no return. Overall, these three examples show that Transhumanism is in our culture more than we notice or even understandsoon transhumanism will be completely immersed in our society without us even noticing.

Overall it is evident that there are multiple different opinions and views someone may have concerning the debate of Transhumanism and genetic manipulation. One may accept in part of the Transhumanist movement, some of its scientific methods but not others. Or one might reject any and all manipulation. Some people think that a genetically manipulated society will cause large differences in out society; but one might become more accepting, such enhancement as eradicating diseases. As the technology continues to develop even more areas of concern and disengagement are sure to arise between Transhumanists and bio-conservatives. But the fact that bio-engineering from vaccinations and flu shots to the potential eradication of aids is likely to find multiple points where one draws his or her No Trespassing Line!

Works Cited

Alcors Mission. Cryonics: Alcor Life Extension Foundation. 25 Sept. 2013 <http://www.alcor.org/>.

Cardiff School of English Communication and Philosophy. Professor Ruth Chadwick. 02 Nov. 2013 <http://cardiff.ac.uk/encap/contactsandpeople/profiles/chadwick-ruth.html>.

John Jefferson Davis. Wikipedia. 29 Nov. 2012. Wikimedia Foundation. 02 Nov. 2013 <http://en.wikipedia.org/wiki/John_Jefferson_Davis>.

Leon Kass. Wikipedia. 24 Sept. 2013. Wikimedia Foundation. Oct. 2013 <http://en.wikipedia.org/wiki/Leon_Kass>.

Max More. Wikipedia. 23 July 2013. Wikimedia Foundation. 26 Sept. 2013 <http://en.wikipedia.org/wiki/Max_More>.

Nano-Bio-Info-Cogno: Paradigm for the Future. H+ Magazine. 12 Feb. 2010. Oct. 2013 <http://hplusmagazine.com/2010/02/12/nano-bio-info-cogno-paradigm-future/>.

Nanotechnology. Credo Reference. 2005. Nov. 2013 <http://search.credoreference.com/content/topic/nanotechnology>.

Nanotechnology. Wikipedia. 25 Oct. 2013. Wikimedia Foundation. 2013 <http://en.wikipedia.org/wiki/Nanotechnology>.

Outline of transhumanism. Wikipedia. 23 Oct. 2013. Wikimedia Foundation. Oct. 2013 <http://en.wikipedia.org/wiki/Outline_of_transhumanism>.

Rosario Isasi. Wikipedia. 22 Feb. 2013. Wikimedia Foundation. Oct. 2013 <http://en.wikipedia.org/wiki/Rosario_Isasi>.

School of Public Health. Boston University. Sept. 2013 <http://www.bu.edu/sph/?option=com_sphdir>.

Transhumanist FAQ. Humanity +. 22 Sept. 2013 <http://humanityplus.org/philsophy/transhumanist-faq/>.

Berger, Michael. Nanotechnology, Transhumanism and the Bionic Man. NanoWerk. 28 May 2008. Oct. 2013 <http://www.nanowerk.com/spotlight/spotid=5848.php>.

Bostrom, Nick. Home Page. Nick Bostrom. Oct. 2013 <http://www.nickbostrom.com/>.

Bostrom, Nick. In Defense of Posthuman Dignity. In Defense of Posthuman Dignity. 8 May 2007. Oct. 2013 <http://www.nickbostrom.com/ethics/dignity.html>.

Bostrom, Nick. Transhumanist Values. Transhumanist Values. May 2005. Oct. 2013 <http://www.nickbostrom.com/ethics/values.html>.

Goffi. Transhumanism & Bioconservatives. Transhumanism & Bioconservatives. Sept. 2013 <http://philosophie.ens.fr/IMG/GOFFI JEUD HPS ENS ULM S2 2012 2013.pdf>.

Gordijn, Bert, and Ruth F. Chadwick. Medical Enhancement and Posthumanity. [Dordrecht]: Springer, 2008.

Hook, Christopher. Transhumanism and Posthumanism. Yumpu. 1 Oct. 2013 <http://www.yumpu.com/en/document/view/13072648/transhumanism-

and-posthumanism-gale>.

Lilley, Stephen. Transhumanism and society: The social debate over human enhancement. Dordrecht: Springer, 2013.

More, Max. The Extropian Principles 2.5. The Extropian Principles 2.5. July 1993. <http://www.aleph.se/Trans/Cultural/Philosophy/princip.html>.

Sandberg, Anders. Definitions of Transhumanism. Definitions of Transhumanism. 22 Sept. 2013 <http://www.aleph.se/Trans/Intro/definitions.html>.

[2] Are You a Transhuman?: Monitoring and Stimulating Your Personal Growth in a Rapidly Changing World (1989)

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Genetic Medicine Isn’t Moving Faster Than the Speed of …

Posted: May 3, 2019 at 10:48 am

Faye Flam is a Bloomberg Opinion columnist. She has written for the Economist, the New York Times, the Washington Post, Psychology Today, Science and other publications. She has a degree in geophysics from the California Institute of Technology.

Weve had plenty of time to ponder the medical ethics.

Source: Hulton Archive, via Getty Images

Source: Hulton Archive, via Getty Images

The news that scientists may have finally used gene therapy to cure the bubble boy immune disorder, SCID-X1, came as a surprise not because it happened so fast, but because it took so long that it had begun to seem impossible.

Scientists were talking about revolutionizing medicine with gene therapy back in the 1980s, and the first child with a different form of the disease, called SCID-ADA, was given gene therapy in 1992. By 2000, doctors were treating the first kids with SCID-X1. But there were problems. Some of them developed leukemia.

Theres a belief that became pervasive in the 1990s that medicine is moving so fast that ethics cant keep up. Science stories in the news would refer toBrave New World or Frankensteins monster. But now that were living in that long-imagined future, it looks like science isnt keeping pace with the hype, which over the years has included promises of cures tied to the human genome project, the expectation that gene therapy would be commonplace, and even the weird belief that cloning would replace sex as the preferred method of human reproduction.

Things havent quite panned out that way. To better understand why, I talked with Jonathan Kimmelman, a medical ethicist at McGill University in Canada, and an expert in human experimentation. He said that despite all the hype, medical technology doesnt leap forward with every new idea the way other kinds of tech can. The ethics of human research slows things down.

Not that medical ethics is easy. The challenge for ethicists, and for society, is to judge research decisions based on what the scientists knew at the time, not the outcome. Unethical researchers might get lucky, and good ones might get very unlucky. By those standards, he said, the researchers who accidentally caused some SCID patients to get leukemia were still taking an ethically acceptable risk, given the scale of the potential benefits, but researchers at the University of Pennsylvania whose experiment killed an 18-year-old subject were not.

In that 1999 case, Jesse Gelsinger died from an experimental gene therapy aimed at curing a different genetic disorder one less life-threatening than SCID. His immune system mounted a deadly reaction to the virus used to insert the gene into his cells a deactivated cold virus called an adenovirus.

In retrospect, there were problems with that trial financial conflicts of interest, worrisome signs in animal studies that were ignored, and some irregularities in the way the human subjects were treated, said Kimmelman, who has written a book about the case. After the death, lots of people claimed to have seen these problems, but, sadly, none of them took the initiative to blow the whistle.

SCID gene therapy trials progressed more carefully, even though the disease was claiming lives with each passing year. A defective gene prevents the bone marrow from creating working immune cells, so kids with the disease have essentially no immune system. This came to public attention in the 1970s, when doctors found a way to keep the famous bubble boy, David Vetter, alive until the age of 12 by sealing him into a sterile plastic enclosure.

Gene therapy seemed like a promising solution. Doctors knew which genes were damaged, and they knew that they need to get working copies into the patients bone marrow.

But theres another layer of precision needed: It can matter where newly introduced genes get incorporated into the persons chromosomes. Viruses cant be programmed to put them in any specific place. Scientists knew, said Kimmelman, that getting the working versions of these genes into the wrong places might trigger leukemia. They thought it was very unlikely, but realized only after the fact that the viruses tended to preferentially place the genes in locations where they increased risk. In 2002, the SCID-X1 trial was stopped after the disease affected four children.

Over the years, scientists have examined other, safer vectors, and, counterintuitively, found that for SCID-X1, their best bet was a deactivated human immunodeficiency virus (HIV). These latest experiments, done in St. Judes Childrens Research Hospital in Memphis and published in the New England Journal of Medicine, took steps to prevent leukemia. Its still early, but the researchers say that so far the results look promising.

A similar standard should apply to the claimed gene-edited babies allegedly born in China late last year. The ethics has to be judged on the risks that were taken at the time, not the outcome, which may never be known given the secrecy surrounding the research. The babies - twin girls - were essentially human guinea pigs. The only disease involved was the fathers HIV-positive status, but there are safe ways to make sure a fathers virus isnt passed to his offspring.

The risks of this are still relatively unknown, and the fact that the SCID researchers misjudged the risk of giving their subjects leukemia should serve as a warning. Once again, in the case of the Crispr babies, the ethical principles were there, but they were broken maybe by a rogue scientist but possibly by one whose experiments were known and fundedby the Chinese government. Kimmelman points out that people have been debating the ethics of genetic engineering on unborn children since the 1970s, soon after the debut of genetic engineering.

In the medical community, there was almost universal agreement that the experiment was unethical because the twin girls were subject to unnecessary risk. The main problem with genetic technology isnt the need to prevent the birth ofFrankensteins monster, but to follow the ethical principles that Hippocrates wrote about more than 2,000 years ago. The needs of patients have to come first, even if it slows down the pace of progress.

This column does not necessarily reflect the opinion of the editorial board or Bloomberg LP and its owners.

To contact the author of this story:Faye Flam at fflam1@bloomberg.net

To contact the editor responsible for this story:Philip Gray at philipgray@bloomberg.net

Before it's here, it's on the Bloomberg Terminal.

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Stem Cell Therapy in Little Rock – Chiropractor Little Rock AR

Posted: May 3, 2019 at 10:48 am

What is Stem Cell Therapy?

Stem cell therapy is the administration of umbilical cord stem cells (UCSC) into a patients body based on the recommendation from your medical provider or nurse practitioner. The cells can be administered through injection or IV infusion to maximize the therapys reach.

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Stem cells are undifferentiated cells that are capable of giving rise to indefinitely more cells of the same type. They have the remarkable potential to develop into many different cell types in the body and serve as what can be accurately described as an internal repair system, replenishing other cells. Each divided cell has the potential to become another type of cell with a specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Umbilical Cord Stem Cells are derived exclusively from the umbilical cord tissue of healthy birthed babies & healthy mothers, which is the safest and least-invasive method of extraction available.

Seek out degeneration: They build, repair, and grow new tissue

Anti-inflammatory: They are effective in reducing inflammation

Immunomodulatory: They help modulate the bodys immune responses

Its the future of medicine. A search of http://www.clinicaltrials.gov provides information on more than 4,000 clinical trials being conducted worldwide.

Pluripotent: A pluripotent cell has the capability of developing into various types of cells or tissues

self-renewal: Stem cells replicate themselves every 28 hours for 65 generations, giving rise to millions of undifferentiated cells

If possible, stop or reduce all aspirin products, non-steroidals, Vitamin E supplementation, and the use of fish oil at least five days before the therapy. Be sure to stay hydrated prior to the procedure.

The duration of the therapy is short, simple, and can take between ten to twenty minutes depending on the amount administered and the procedure chosen. This time will include cleaning and prepping the injection points.

If possible, stop or reduce anti-inflammatory medication for at least one to two weeks. Remember: Stem cells replicate every 28 hours through 65 cycles of replication.

At 3-4 Weeks Post-Therapy: Light exercises and stretching; no high-impact activities.

One Month Post-Therapy: Aggressive stretching, light-weight training; as tolerated by joints

Second Month-Post Therapy: Increase workout regiment and sport-specific activities

Yes! The use of Umbilical Cord Stem Cells is FDA cleared and our provider abides by all of the most stringent medical guidelines. Your comfort, safety, and recovery are the top concern.

The cells are rigorously tested and screened under NIH, FDA, AATB, and AABB guidelines.

Because UCSC are less mature than other cells, the bodys immune system is unable to recognize them as foreign and therefore, they are not rejected. There has never been a documented instance of rejection in graft vs. host.

Journal of Translational Medicine 2007, Stem Cell Therapy for Autism. Thomas E. Ichim, Fabio Solano, Eduardo Glenn, Frank Morales, Leonard Smith, George Zabrecky, and Neil H. Riordan

See this testimonial about how Stem Cell Therapy in Little Rock is helping our patients. Natural State Integrative Health is one of the few locations in Central Arkansas offering this cutting edge treatment for pain management.

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Low T & Testosterone Replacement Therapy in San Diego …

Posted: May 3, 2019 at 10:46 am

If you ask anybody from my inner circle, they would all say that Im athletic, handsome, and energetic. I didnt feel like any of those a little after turning 43. I gained a little over 15 pounds, lost patches of hair over my body, and couldnt get good sleep so I was always tired. I did some research and they were all symptoms of low testosterone. I spoke to my wife and she mentioned that her brother-in-law went through the same thing and went through a TRT protocol with GameDay. I did the same and couldnt be happier. The icing on the cake is the fact that GameDay worked with my insurance plan!

-- Todd A., Carlsbad

Words you never want to hear when having sex: Is everything okay? My wife noticed the lackluster sex and Im glad she said something because if not I would have never found out about GameDay and their treatment for low testosterone levels. After just a couple of months, TRT is rocking my life and rejuvenated my sex life. My wife and I are forever thankful that GameDay was able to help me with their dedicated support and expert knowledge. We spoke to a few other clinics and we didnt feel comfortable with the way they were just trying to push us towards a payment.

-- Mike R., Carlsbad

I have noticed from start to finish that my energy levels have been much better with the help of GameDays TRT treatment. Prior to it, my mind was foggy and I couldnt get any deep sleep which made working in sales extremely difficult. With all of the traveling and constant relationship building that is expected of me, I just couldnt keep up and underperformed which never happens. My boss took me aside and suggested I take some time off to get things aligned. With the time off, I was able to find a solution through GameDay. Im now back at work and hitting my performance goals again.

-- Bill M., San Marcos

Things in my life werent getting much worse in the past year. I was tired but I felt like who wasnt? I gained weight but I also worked a sedentary job. What really got me was that when I was out with my friends and an attractive person passed me, I had no reaction. That was a wake up call for me. My friend actually got treatment at GameDay and highly recommended reaching out. Best decision ever. The staff had such an expertise and were straightforward about what was possible and what should be expected. Within 3 months, I feel overall more alive and I gained more confidence. 10/10 awesome experience.

-- Andrew K., San Diego

GameDay has greatly improved my life and I highly recommend everybody to go give them a visit. Theyre professional and, more importantly, attentive to what I was saying. I was so relieved after meeting with the GameDay team - the search for a treatment was finally over and things can only move up from here! My girlfriend was also glad that GameDay was able to provide a treatment that not only was effective, but also reassuring knowing that each visit was getting me back to my normal self. Im not longer lethargic throughout the day and Ive even been told that I was glowing haha!

-- Nick W., Carlsbad

No dude likes to go to a clinic, let alone a mens health clinic. It's uncomfortable to talk about especially in regards to something below the belt being wonky. In addition, mentally I felt off and my energy was non-existent. Things like this, I usually just avoid but things got to a point where I had to reach out to GameDay. Hands down, this experience was as comfortable as it could have possibly bee. The staff were awesome. They were all positive vibes and its clear that they pull out all the stops for every patient. If youre looking for discreet, professional, and quick service reach out to GameDay. Theyll no doubt care for you.

-- Rick T., Carlsbad

When I reached out to GameDay, I had so many hands in all sorts of problem buckets. My sleeping was horrible and had this permanent brain fog. Even when I did manage to get a good amount of sleep, I was exhausted and empty. After going to the clinic and starting my treatment plan, I slept like a baby. When I wake up now, Im a different person. I feel like I can take on whatever is in my way. On top of that, my facial hair is coming in more fully. Its crazy to think that all my problems were stemmed from this one deficiency in my life, thank you GameDay!!!

-- William W., Carlsbad

I knew something was wrong when my sex drive dropped. Docs were so willing to write viagra scripts but stonewalled any indication that hormone levels were off. GameDay evaluated my case without any judgement or discrimination. I got a treatment plan quickly and it was affordable since they accept insurance. 1.5 months in, I can say that my sex drive is steadily increasing. I feel like the loss of confidence and vigor is slowly being repaired which is more than I can ask for. Happy that I reached out, would recommend.

-- Steve K., San Marcos

I truly feel blessed that my insurance covered services at GameDay. I reached out interested in improving what I had suspected to be low T levels. As I know many go through, my local PCP didnt want anything to do with that. I sought out another provider they actually recommended GameDay. The treatment plant they made me, I felt a difference within weeks. They even worked with my insurance and kept me in the loop despite my may questions. So happy that I ended up at GameDay and wouldnt change it for anything.

-- Daniel A., Carlsbad

GameDay gave me back the vigor of life as I call it. I came into GameDay because they accept insurance but I was a little skeptical. Ive been working with my physician for years, but he recently moved away. Within a month, joint pain was close to zero, I recovered quicker, and when I worked out I could progressively do more weight almost every time I came back. Being on the treatment plan let me experience working out and moving around like I was 20 again, They make the world of difference to my quality of life and I will never stop recommending them.

-- Steven B., Carlsbad

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Skin stem cells: where do they live and what can they do …

Posted: May 1, 2019 at 11:53 pm

One of the current challenges for stem cell researchers is to understand how all the skin appendages are regenerated. This could lead to improved treatments for burn patients, or others with severe skin damage.

Researchers are also working to identify new ways to grow skin cells in the lab. Epidermal stem cells are currently cultivated on a layer of cells from rodents, called feeder cells. These cell culture conditions have been proved safe, but it would be preferable to avoid using animal products when cultivating cells that will be transplanted into patients. So, researchers are searching for effective cell culture conditions that will not require the use of rodent cells.

Scientists are also working to treat genetic diseases affecting the skin. Since skin stem cells can be cultivated in laboratories, researchers can genetically modify the cells, for example by inserting a missing gene. The correctly modified cells can be selected, grown and multiplied in the lab, then transplanted back onto the patient. Epidermolysis Bullosa is one example of a genetic skin disease, where patients can benefit from this approach. Work is underway to test the technique.

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Stem Cell Research Facilities – Indiana Stem Cell

Posted: May 1, 2019 at 11:53 pm

BONE MARROW VS. FAT DERIVED STEM CELLS- IS THERE A CONTROVERSY?

Whether your adult mesenchymal stem cells come from bone marrow or from fat probably does not make a difference in terms of clinical results. Although some centers claim that bone marrow derived cells are superior to fat derived cells, there is no evidence to substantiate that. The fact that there are many more studies on bone marrow cells does not prove clinical superiority but merely supports the obvious fact that fat derived cells are based on more recent discoveries and although evidence is accumulating, there are far fewer studies using these cells. It is important that one is not mislead by the word bone in bone marrow, possible implying that since this is an orthopedic source it might be better for treating orthopedic conditions such as cartilage regeneration. In fact, the bone marrow is part of the reticulo-endothelial system and just happens to be found in the center of bone. All of these types of cells are equally primitive and have the potential to differentiate into mature functional tissues. For many disease types such as cardiac pathology, adipose derived cells appear to be showing superiority to bone marrow derived cells. This may be related to the well documented qualitative and quantitative attrition in bone marrow stem cell counts related to age and chronic illness (chronic disease causes bone marrow suppression). Such changes in the number of cells over time and the quality of cells dependent on health have not been seen in fat derived stem cells. Fat derived cells are a natural choice for our investigational work considering their easy and rapid availability in extremely high numbers.

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Stem Cell Research Facilities - Indiana Stem Cell

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Journal of Nanomedicine and Biotherapeutic Discovery- Open …

Posted: May 1, 2019 at 11:51 pm

Nanomedicine is an application of nanotechnology which made its debut with greatly increased possibilities in the field of medicine. Nanomedicine desires to deliver research tools and clinically reformative devices in the near future.

Journal of Nanomedicine & Biotherapeutic Discovery is a scholarly open access journal publishing articles amalgamating broad range of fields of novel nano-medicine field with life sciences. Nanomedicine & Biotherapeutic Discovery is an international, peer-reviewed journal providing an opportunity to researchers and scientist to explore the advanced and latest research developments in the field of nanoscience & nanotechnology.

This is the best academic journal which focuses on the use nanotechnology in diagnostics and therapeutics; pharmacodynamics and pharmacokinetics of nanomedicine, drug delivery systems throughout the biomedical field, biotherapies used in diseases treatment including immune system-targeted therapies, hormonal therapies to the most advanced gene therapy and DNA repair enzyme inhibitor therapy. The journal also includes the nanoparticles, bioavailability, biodistribution of nanomedicines; delivery; imaging; diagnostics; improved therapeutics; innovative biomaterials; regenerative medicine; public health; toxicology; point of care monitoring; nutrition; nanomedical devices; prosthetics; biomimetics and bioinformatics.

The journal includes a wide range of fields in its discipline to create a platform for the authors to make their contribution towards the journal and the editorial office promises a peer review process for the submitted manuscripts for the quality of publishing. Biotherapeutics journals impact factors is mainly calculated based on the number of articles that undergo single blind peer review process by competent Editorial Board so as to ensure excellence, essence of the work and number of citations received for the same published articles.

The journal is using Editorial Manager System for quality peer review process. Editorial Manager is an online manuscript submission, review and tracking systems. Review processing is performed by the editorial board members of Journal of Nanomedicine & Biotherapeutic Discovery or outside experts; at least two independent reviewers approval followed by editor approval is required for acceptance of any citable manuscript. Authors may submit manuscripts and track their progress through the system, hopefully to publication. Reviewers can download manuscripts and submit their opinions to the editor. Editors can manage the whole submission/review/revise/publish process.

Submit manuscript at http://editorialmanager.com/chemistryjournals/ or send as an e-mail attachment to the Editorial Office at[emailprotected]

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Gene Therapy : Homology Medicines

Posted: May 1, 2019 at 11:50 pm

Homology Medicines gene therapy approach utilizes our proprietary AAVHSC vectors to deliver a functional gene to a cell where there is a missing or mutated gene. Once delivered, the functional gene may lead to therapeutic protein expression. With gene therapy, the genes do not integrate into the genome so this approach can be curative in slow- or non-dividing cells (e.g., adult liver or central nervous system).

Our gene therapy construct includes a functional copy of the gene and a promotor sequence that is designed to enable the gene to be turned on in the cell and ultimately transcribed to express a therapeutic protein without integrating into the genome.

Our unique vectors have demonstrated significant systemic biodistribution to multiple tissue types in preclinical studies, including liver, central nervous system (CNS), muscle (skeletal and cardiac) and eye*. This enables us to potentially address a broad range of monogenic diseases.

Our lead development program is an AAVHSC-mediated gene therapy treatment for adults with the rare disease phenylketonuria. Learn more about our pipeline and therapeutic focus.

*Homology data on file; Ellsworth JL, Smith LJ, Rubin H, et al. Widespread transduction of the central nervous system following systemic delivery of AAVHSC17 in non-human primates. American Society of Gene & Cell Therapy Annual Meeting. May 2017.

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Gene Therapy : Homology Medicines

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Stem Cells and Hearing Loss – Sound Relief Hearing Center

Posted: May 1, 2019 at 12:51 am

Stem cells have an extraordinary power: the ability to divide for indefinite periods in culture and to give rise to specialized cells. Countless research studies have focused on stem cells and the many conditions that could potentially be treated using them, which has led audiologists to wonder about the relationship between stem cells and hearing loss. Do stem cells hold the key to a cure for hearing loss or tinnitus?

Over 25,000 hair cells exist in the cochlea, an organ in the inner ear. These cells are extremely important to the process of hearing, as they detect and respond to sound, transmitting nerve signals to the brain. Unfortunately, hair cells are also sensitive and unable to regenerate. Exposure to loud noises, aging, infections, and drugs can all inflict permanent damage on these vital structures.

Research on stem cells and hearing loss has focused on the potential for stem cells to develop and function as hair cells. Scientists have discovered the presence of stem cells in the inner ears of mice, chicks, and zebra fish (source). Under the right conditions, the stem cells can develop into cells that are remarkably similar to hair cells. The question is, can we transfer this amazing ability to humans?

Although a cure does not yet exist, the results obtained thus far are promising. Researchers at Stanford Medicine, Rutgers University, MIT, Brigham and Womens Hospital, and Massachusettes Eye and Ear have all been making progress with research involving stem cells and hearing loss. In addition, scientists at Kyoto University in Japan have conducted research that may help with hearing loss and tinnitus.

Researchers at Stanford Medicine are working to develop a biological method to repair the cochlea and treat hearing loss. Their approach involves the surgical placement of stem cells within the cochlea, which then develop and function as hair cells. In their laboratory, they have mimicked the formation of embryonic mouse ears to create stem cells that look and act like hair cells. If millions of hair cells could be produced in the ear, this research could restore normal hearing to people afflicted by hearing loss.

The key may be induced pluripotent stem cells (iPS), adult cells, taken for example from a patients own skin that have been genetically reprogrammed to revert back to stem cells. These cells would allow the treatment of hearing loss using the patients own cells. Embryonic stem cells also present an exciting opportunity for progress.

The team at Stanford is currently attempting to produce human hair cells in a culture dish, which would be a revolutionary achievement and could lead to effective hearing loss therapy through cell transplantation.

Scientists at Rutgers UniversityNew Brunswick are also working with inner ear stem cells, converting them to auditory neurons and potentially reversing hearing loss. The challenge is controlling the division of the stem cells; if they divide too quickly, they pose a cancer risk.Currently, researchers can control the stem cells in a Petri dish.

The study relies on the gene NEUROG1, which the scientists overexpress to transform the inner ear stem cells into auditory neurons. Due to its potential for proliferation, the researchers must be cautious when working with this gene. Managing the chromatin state of the targeted genes can reduce this dangerous tendency to rapidly reproduce.

Researchers at MIT, Brigham and Womens Hospital, and Massachusetts Eye and Ear stumbled upon their research with stem cells and hearing loss. While studying intestinal cell regeneration, they noticed a similarity between intestinal stem cells and the cochleas structural support cells. They conducted a test to explore whether regeneration would work in the cochlea as it had in the intestines, and their theory proved correct. This discovery could help reverse sensorineural hearing loss. Although the treatment will require more research, testing, and approval by the FDA before it hits the market, the researchers are optimistic and predict that the drugs will be injected into the middle ear.

Finally, researchers at Kyoto University discovered a new way of applying stem cells that prevents their deaths. Stem cells often die due to failure to bypass the glial scar, a hallmark of neural damage that is thought to act as a barrier for cell transplantation (source). The scientists found that applying the stem cells to the surface of the glial scar instead of underneath it helped them survive. The cells grew from the damaged segment of the auditory nerve, which carries information from the cochlea to the brain, and could help restore auditory function. Tinnitus sometimes results from an issue with the connection between external sound and the central nervous system, which is often caused by damaged hair cells in the cochlea. Thus, restoring this connection through stem cell transplantation could eliminate tinnitus.

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Keep an eye out or should I saykeep an ear out? for future news regarding the connection between stem cells and hearing loss. Although the discoveries are exciting, a lot more research must be done to address the issues presented by stem cells. Scientists must find a way to prompt stem cells to differentiate in the ear without allowing them to die or grow uncontrollably. This solution isnt perfect yet, but the future looks bright for stems cells and hearing loss.

If you areexperiencing hearing loss, tinnitus, hyperacusis, or another auditory issue, please contact theSound Relief Hearing Centerin Colorado. We are independently owned, so we always have the patients best interests at heart, and our state-of-the-art technology ensures that our patients receive the best treatment available. With our unparalleled excellence in the hearing industry, our dedication to patient satisfaction, and our commitment to helpingpeople control and conquer their hearing issues, you can count on Sound Relief Hearing Center forsupport and assistance.

To learn more about us, please browseour website, visit ourYoutube channel, or give us a call at 720-259-9962. You can alsoschedule an appointment onlineto meet with one of our audiologists. We look forward to hearing from you!

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Stem Cells and Hearing Loss - Sound Relief Hearing Center

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Arlington Stem Cells | Neuropathy & Pain Centers of Texas

Posted: May 1, 2019 at 12:51 am

The Neuropathy & Pain Centers of Texas is helping Arlington, Texas patients stop chronic pain with customized non-invasive treatment options to address your unique health needs and meet your health goals. We specialize in Advanced Regenerative Cell Therapy that offers safe and effective solutions for patients with a wide array of conditions. Our expert staff focuses on total body health and works with you to design your personal path to ending your chronic pain and reclaiming your life. Our innovative Advance Regenerative Cell Therapy has been proven effective in treating degenerative arthritic conditions, hip, knee, shoulder and elbow joint conditions, rotator cuff tendonitis, Achilles tendonitis and carpal tunnel syndrome.

Traditional treatment plans often rely on medications with dangerous side effects and risky invasive surgeries, but The Neuropathy & Pain Centers of Texas in Arlington is focused on providing patients an alternative path to healing and living a pain free life with Advanced Regenerative Cell Therapy that helps you avoid these harmful options. Patients living with chronic pain from degenerative joint conditions like hip osteoarthritis regularly endure steroid injections, never-ending pain medication protocols and joint replacement surgery often with little to no relief from their pain. Advanced Regenerative Cell Therapy treatments work to heal the underlying cause of your chronic pain and gives patients long-term results they can trust instead of just masking symptoms.

At The Neuropathy & Pain Centers of Texas we take creating a personalized patient experience seriously so its only natural that we provide a revolutionary treatment like Advanced Regenerative Cell Therapy that works with your body on a cellular level with cutting edge healing power. Advanced Cell Therapy commands growth factors and cytokines to the affected area and helps to repair and regenerate bone, ligaments, tendons and cartilage. Our skilled staff is dedicated to helping you stop chronic pain with a healthy, safe, non-invasive treatment. Call our team Arlington, Texas today and discover how Advanced Regenerative therapy can change your life.

Neuropathy & Pain Centers of Texas offers functional medicine, including physical therapy in Fort Worth, TX, 76132 and Arlington, TX, 76010. For yourFREE consultation, call us today at817-618-6443 in Fort Worth or 817-678-8558 in Arlington.

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Arlington Stem Cells | Neuropathy & Pain Centers of Texas

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