CBD And CBG Show Promising Results In Treating Glioblastoma Brain Tumors – The Fresh Toast

By Nina Zdinjak

MGC Pharmaceuticals , a publicly-traded cannabis company, recently finalized pre-clinical trial research ofcannabinoids as a potential treatment for glioblastoma,anaggressive brain cancer.Theresults were positive,reported CityA.M.

The European-based bio-pharma company specializing in the production and development of phytomedicines said that the three-year in-vitro trial delivered outstanding results.

The research, conducted in collaboration with theNational Institute of Biology in Slovenia with30 biopsy samples from 18 patients,firstexamined how cannabinoids such as CBD can be used as a treatment for cancerous tumors. MGC also researched THC and later replaced it with cannabigerol, known as CBG, which has no known psychotropic effects.

The study took more than 5,800 cell tests to determine the most efficient concentration and ratios of CBD and CBGin the treatment formulation.

The results revealed the efficacy of cannabinoidsin treating glioblastoma, as well as the most efficient ratio of CBD:CBG in inhibiting the tumors viability, causing a cascade of biological processes resulting in the death of glioblastoma and stem cells,reported BusinessCann. This is important because glioblastoma stem cells are the primary cause of the diseases progressionand areresistant to standard treatments.Glioblastoma is the most common, fast-growing, and aggressive brain tumor. Composed of diverse cell types, the prognosis is always poor.

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The results of this trial are enormously exciting both for the company, and for the treatment of fatal cancerous tumors, saidRoby Zomer,co-founder and managing director at MGC Pharmaceuticals.

MGC Pharmas research has demonstrated the effect of naturally derived cannabinoid products on stage IV brain tumors without the use of toxic chemotherapy components. We are proud of the work achieved thus far and are looking forward to advancing our proprietary formulation to the next stage of clinical trials.

This is not the first successful research on the potential of CBD as a treatment for this type of brain tumor.

Researchers at theMedical College of Georgia at Augusta University, released astudyin December revealing thatinhaled CBD shrunkthe size of glioblastoma tumorsin an animal model.

The study suggested thatinhaled CBD reduces the size of glioblastomathrough the reduction of the essential support of its microenvironment. Researcherschose the inhaled approach to make sure the compound found in the cannabis plant reached the brain.

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We saw a significant reduction in the size of the tumor and its microenvironment was different, after only seven days of treatment,saidDr.Babak Baban,immunologist and associate dean for research at the Dental College of Georgia at Augusta University.

In eight days the aggressive brain tumor was formed in the brain of the mice, and the following day they started treating them with CBD via inhalation or placebo. The researchers discovered thatCBD altered the tumors ecosystem, or supportive tumor microenvironment, and restored levels of inflammation that attack glioblastoma.

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It is about immune balance, said Baban, the corresponding author of the study.

He explained that the human immune system is regularly fighting cancerous or precancerous cells, but when a tumor is completely established, it takes charge. This means that the tumor creates a state of more chronic inflammation that ends up protecting it from the immune system.

While further research is needed, these results are a great start as they offerhope to theapproximately250,000people worldwide struggling with this devastating condition.

This article originally appeared on Benzinga and has been reposted with permission.

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CBD And CBG Show Promising Results In Treating Glioblastoma Brain Tumors - The Fresh Toast