Category Archives: Epigenetics

Pune, Maharashtra, December 10 2021 (Wiredrelease) Market.Biz :Market.biz recently released a new research report on the Wind Turbine Market which uncovered accurate information about the long-term prospects of the global and regional market. It has orderly defined the market scenario and highlights the industrial developments with Wind Turbine leading players. Further, It covers the market specifications by chapters and industry procedure that will absolutely help our readers point to the Wind Turbine industry perspective to promote the stability of the cost and revenue structure.

Market Estimations:

The main purpose of this report is to provide readers with factual information about the Wind Turbine market, to help them collect and develop viable strategies based on the general information provided on the website. Detailed market statistics of Wind Turbine reveals the current status, projections, and future classification such as product type, end-use, region, and main industry of Wind Turbine Market. In addition, it sheds light on industry factors such as development, supply, and demand, its current outlook, growth trajectory over the decades, and opportunities for Wind Turbine industry participants around the world. Moreover, the report analyzes business plans, sales, and profits, production volumes and sales, suppliers of raw materials, and buyers of Wind Turbine Industry for information needs and distribution rates.

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The Competitive Landscape segment in the Wind Turbine market report is based on the potential of the major players in the current market. This section of the report highlights various important market makers. It helps the user understand the systems and overall effort that the player focuses on when looking for battles. The complete report provides an excellent overview of the Wind Turbine market. Competitive Landscape is based on COMPANY PROFILES, COMPANY OVERVIEW, FINANCIAL HIGHLIGHTS, PRODUCT PORTFOLIO, SWOT ANALYSIS, KEY STRATEGIES, AND DEVELOPMENTS.

The main actors identified in this report are: Goldwind, LEITWIND, Nordex Energy, Senvion, Siemens Wind Power and Renewables, Vestas, Suzlon, ENERCON, GAMESA ELECTRIC, GE Wind Turbines

The report presents a global segmentation of the Wind Turbine market based on product type, end-user, and region. The report provides an analysis of selected market segments from 2016 to 2020 and forecasts for the period from 2021 to 2030. Each segment is calculated in terms of revenue generated (Million USD) and Average Annual Growth Rate (CAGR). In the additional section, the Wind Turbine report provides a market breakdown study of major regions of the world such as North America, Asia-Pacific, Europe, South America, The Middle East, and Africa, and the Rest of the World.

Product Types: Horizontal-Axis Wind Turbine, Vertical-Axis Wind Turbine

Target Applications: Land Wind, Offshore Wind

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Imperative Points Covered In The Global Wind Turbine Market Report:

Historical and current market sizing report forms the basis of the global Wind Turbine market and is expected to grow in the future.

Information was given on the competitive environment in the Wind Turbine industry, and this refers to the visibility dashboards of competing companies and their respective market shares by value (in millions of dollars) and volume (in units).

This report analyzes the global Wind Turbine market by product, end-user, and region, and provides a cost forecast (in millions of US dollars) over the next few years.

The global market value of Wind Turbine described in the report is complemented by the collection of data and information for each region.

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Global Printed Cartons Market By Type(Paperboard, Corrugated Board, Kraft Board, Coated Paper, Liquid Board), By Application(Food and Beverage, Hardware and Electronics, Homecare, Healthcare, Cosmetics and Personal Care), By Country, Competition Scenario and Forecast by 2030. Printed Cartons Market Size Is estimated to reach US $ 1,65,570.5 Million By 2030, From US $ 1,23,200. Million in 2020, with the CAGR Of 3% By 2030. https://market.biz/report/global-printed-cartons-market-gm/

Global Rail Equipment Market By Type(Locomotives, Passenger trains, Freight cars, CRH trains, Subway trains), By Application(Grain Growing, Sugar Cane Growing, Black Coal Mining, Iron Ore Mining, Rail Freight Transport, Rail Passenger Transport), By Country, Competition Scenario and Forecast by 2030. Rail Equipment Market Size Is estimated to reach US $ 1,62,983.4 Million By 2030, From US $ 1,23,992.5 Million in 2020, with the CAGR Of 2.8% By 2030. https://market.biz/report/global-rail-equipment-market-gm/

Global Picosecond Lasers Market By Type(<50W, 50-100W, >100W), By Application(Scientific Research and Military, Medical and Aesthetic, Micromachining/Material Processing), By Country, Competition Scenario and Forecast by 2030. Picosecond Lasers Market Size Is estimated to reach US $ 9,831.8 Million By 2030, From US $ 1,231.1 Million in 2020, with the CAGR Of 23.1% By 2030. https://market.biz/report/global-picosecond-lasers-market-gm/

Global Vitreoretinal Surgery Devices Market By Type(Vitreoretinal Packs, Vitrectomy Machines, Photocoagulation Lasers, Illumination Devices, Vitrectomy Probes, Vitreoretinal Surgery Instruments & Kits), By Application(Hospitals, Free Standing Ambulatory Surgery Centers), By Country, Competition Scenario and Forecast by 2030. Vitreoretinal Surgery Devices Market Size Is estimated to reach US $ 1,452.2 Million By 2030, From US $ 1,233. Million in 2020, with the CAGR Of 1.6% By 2030. https://market.biz/report/global-vitreoretinal-surgery-devices-market-gm/

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Cancer Testing Product Market report focused on the comprehensive analysis of current and future prospects of the Cancer Testing Product industry. This report is a consolidation of primary and secondary research, which provides market size, share, dynamics, and forecast for various segments and sub-segments considering the macro and micro environmental factors. An in-depth analysis of past trends, future trends, demographics, technological advancements, and regulatory requirements for the Cancer Testing Product market has been done in order to calculate the growth rates for each segment and sub-segments.

Cancer screening aims to detect cancer before symptoms appear. This may involve blood tests, urine tests, other tests, or medical imaging. The benefits of screening in terms of cancer prevention, early detection and subsequent treatment must be weighed against any harms.

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Top Key Vendors of this Market are:

Epigenetics Ag, Techlab, Positive Bioscience, Agilent Technologies, Bio-Rad Laboratories, Affymetrix, Genextropy Inc., Abbott Diagnostics, Dias Orin S.P.A, Beckman Coulter, Roche Diagnostics, Fujirebio Diagnostics, Johnson & Johnson, Cardinal Health, M Genomics Ltd, Hologic.

Global Cancer Testing Product Market Segmentation:

Market Segmentation: By Type

Lung, Blood, Bone, Others

Market Segmentation: By Application

Breast cancer, Cervical cancer, Bowel cancer, Prostate cancer, Lung Cancer, Pancreatic cancer, Other cancers

Various factors are responsible for the markets growth trajectory, which are studied at length in the report. In addition, the report lists down the restraints that are posing threat to the global Cancer Testing Product market. This report is a consolidation of primary and secondary research, which provides market size, share, dynamics, and forecast for various segments and sub-segments considering the macro and micro environmental factors. It also gauges the bargaining power of suppliers and buyers, threat from new entrants and product substitute, and the degree of competition prevailing in the market.

The report provides insights on the following pointers:

Market Penetration: Comprehensive information on the product portfolios of the top players in the Cancer Testing Product market.

Competitive Assessment: In-depth assessment of the market strategies, geographic and business segments of the leading players in the market.

Product Development/Innovation: Detailed insights on the upcoming technologies, R&D activities, and product launches in the market.

Market Development: Comprehensive information about emerging markets. This report analyzes the market for various segments across geographies.

Market Diversification: Exhaustive information about new products, untapped geographies, recent developments, and investments in the Cancer Testing Product market.

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The influence of the latest government guidelines is also analysed in detail in the report. It studies the Cancer Testing Product markets trajectory between forecast periods. The cost analysis of the Global Cancer Testing Product Market has been performed while keeping in view manufacturing expenses, labour cost, and raw materials and their market concentration rate, suppliers, and price trend.

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Table of Contents

Global Cancer Testing Product Market Research Report 2021 2027

Chapter 1 Cancer Testing Product Market Overview

Chapter 2 Global Economic Impact on Industry

Chapter 3 Global Market Competition by Manufacturers

Chapter 4 Global Production, Revenue (Value) by Region

Chapter 5 Global Supply (Production), Consumption, Export, Import by Regions

Chapter 6 Global Production, Revenue (Value), Price Trend by Type

Chapter 7 Global Market Analysis by Application

Chapter 8 Manufacturing Cost Analysis

Chapter 9 Industrial Chain, Sourcing Strategy and Downstream Buyers

Chapter 10 Marketing Strategy Analysis, Distributors/Traders

Chapter 11 Market Effect Factors Analysis

Chapter 12 Global Cancer Testing Product Market Forecast

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Cancer Testing Product Market to Witness Growth Acceleration | Epigenetics Ag, Techlab, Positive Bioscience Energy Siren - Energy Siren

I stood in front of a book cart that my colleagues and I call recoverymisplaced items that need to be put back in their respective places. I glanced at my watch and read 6:04 p.m. Three more hours until my shift at the local bookstore ended for the day. The store was quiet, except for Mariah Careys All I Want for Christmas Is You playing in the background. A trace of roasted Starbucks coffee beans mixed with the smell of new books lingered in the air.

My mind raced with my plans for the week as I grabbed a book from the cart. Would I be able to catch up on my lectures when I get home? How would I split my studying for my upcoming epigenetics test? When could I start my paper that was due the following Monday? I put the book back where it belonged. What day could I fit a career counselling appointment in my schedule? Did I check-up on my loved ones that day?

I took another book from the cart and paused at the wave of thoughts I was experiencing. The book rested in my hand. The longer I let my thoughts wander, the faster my heart beat, and the more anxious I felt. I hurried to the cash desk, grabbed a piece of receipt paper, and scribbled a quick to-do list. I shoved the paper inside my pocket, let out a sigh of relief, and focused on the book I had been holding titled Good Anxiety: The Power of Harnessing The Most Misunderstood Emotion by Dr. Wendy Suzuki. I smiled.

Ever since watching her famous TED talk, which now has more than seven million views on YouTube, Dr. Suzuki has become an inspiration to me. She is a professor of Neural Science and Psychology in the Center for Neural Science at New York University. She is also an internationally recognized expert on neuroplasticity. Dr. Suzuki was recently named one of the 10 women changing the way we see the world byGood Housekeepingand regularly serves as a sought-after expert for publications includingThe Wall Street Journal,Shape, andHealth, as stated on her website.

When I read more about Dr. Suzukis research and her first book, Healthy Brain, Happy Life: A Personal Program to Activate Your Brain and Do Everything Better, in my first year of undergrad, I became a big fan of her work. I later decided to pursue a specialist in neuroscience at UTM. Now in my third year and after reading Good Anxiety, I had the wonderful opportunity to discuss it with her.

I first asked Dr. Suzuki about the concept of good anxiety. Anxiety and the stress response evolved to protect us, she said. Dr. Suzuki also highlights the importance of shifting ones mindset around anxiety. We need to ask ourselves, how can I make it work for me?

According to her, the first step to having good anxiety is learning how to turn our anxiety levels down. In her book, she mentions that students often reach a level where their performance is impaired due to their high anxiety levels. To avoid reaching this state, Dr. Suzuki suggests breathing deeply using a box breathing technique to naturally activate the bodys parasympathetic nervous system. This technique involves inhaling for four seconds, holding your breath for four seconds, and then exhaling for another four seconds. Its easy to remember and can be used right before youre going to take an exam or before youre going to have a big study session, states Dr. Suzuki. Or in the middle of an anxiety-provoking conversation. Nobody even knows that youre doing it.

Dr. Suzukis second tip is to exercise. Every time you move your body, its like youre giving your brain this wonderful bubble bath of neurochemicals, she adds, explaining that these include serotonin, noradrenaline, dopamine, and endorphins. Studies show that these neurotransmitters immediately improve mood and decrease anxietyeven after just a 10-minute walk. Not only does regular exercise help decrease anxiety, but it also enhances long-term memory and focus, which helps students retain information more easily and for longer periods of time.

I was fascinated by her studies showing that exercise is, as she says, the most transformative thing that you can do for your brain today. She describes that the hippocampus, an area in the brain that is vital for learning and memory, gains brand new brain cells and increases in volume with regular exercise. According to a 2017 study, exercise improves prefrontal cortex function and therefore protects the brain from neurodegenerative disorders like dementia and Alzheimers. Moreover, exercise improves our mood.

Dr. Suzuki and I also discussed the concept of flow. Mihaly Csikszentmihalyi, a Hungarian-American psychologist, describes flow as a state of complete absorption and engagement. In this state, we perform at an optimum level with an almost effortless state of mind. In Good Anxiety, Dr. Suzuki explains micro flow as a shorter, but more frequent flow state that can help us enjoy any experience throughout our day. She describes micro flow as a superpower of anxiety.

After reading more about this, I reflected on the states of micro flow throughout my daymost notably during my neuroplasticity class, where I was fully engaged with my thoughts. Many students can benefit from reflecting on instances of flow or micro flow throughout their week. We can use these to figure out what we are passionate about, which in turn helps us decide what to focus on for our future endeavours.

Inspired by a successful lawyer she met, Dr. Suzuki wrote about turning the what if list of worries that students have into a to-do list. She suggests acting on the worries you can control by looking for coaching, asking a friend to list your best qualities, and getting as much information as you can. For me, I noticed that even scribbling a quick to-do list on a receipt paper at work helped me manage my worries and focus on the present moment.

Dr. Suzukis final message to students emphasizes finding the reasons and joys behind our effort to learn. Everybody right now, take one minute to think about what is joyful to you about the learning that youre doing in this endeavour, she concludes. The joy and the inspiring part is what you get to learn. She advises students to ask themselves what we appreciate in learning. Tell yourself why. Remind yourself why.

Just as Dr. Suzuki inspired me to find my interests, pursue further research in positive neuroplasticity, make the best of my anxiety, and remember my motivation behind choosing further education, I hope she inspires you too. For more information about Dr. Suzuki, her books, and her research, please visit http://www.wendysuzuki.com.

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How can students make the best of their anxiety? - The Medium

Not everyone ages gracefully. Thats true for people who dont take care of themselves as adults, but its also true for someone whose health was jeopardized at a young age from contact with something harmful, like air pollution or poor diet. In particular, smoking exposure during early development has been linked with numerous adverse health conditions, and now a new study shows that it, as well as other harmful pollutants, can cause advanced biological aging.

Early life, beginning in the womb through childhood, is a crucial phase in human development where susceptibility to environmental exposures is higher. Changes brought about during this time period can have a lasting effect on a persons metabolism and physiology, thus leading to either good health or diseases later on in life.

Knowing which and why certain exposures are beneficial or detrimental to early development provides evidence for avoidance or increased contact with them. Because aging is a continuous process that occurs at a cellular level throughout life, it can be measured to estimate health risks. One innovative way to measure biological age is through the use of what is known as an epigenetic clock, which measures DNA methylation in specific regions of the genome.

In an analysis led by the Barcelona Institute for Global Health (ISGlobal), researchers investigated the association of over 100 various environmental exposures and the epigenetic clock of 1,000 or more children. What they found was that tobacco smoke, above all, positively correlated with advanced aging.

The epigenetic clock allows us to assess whether someones biological age is older or younger than his or her chronological age, explains author and ISGlobal researcher, Mariona Bustamante.

Biological, or epigenetic, age acceleration has been linked to several age-related conditions like cancer, cellular senescence, mortality, and more. Although DNA methylation is used to calculate epigenetic age, it is just one mechanism by which epigenetics affects gene expression. Histone modifications, chromatin state, and non-coding RNAs can also impact how genes are expressed.

In the past, most epigenetic aging studies have been performed on adults to evaluate environmental exposure, and usually for just one type of exposure. This study was the first to assess a link between early-life exposome of some 83 prenatal and 103 in early childhood exposure with epigenetic age. The results can be found online in the Environment International journal.

While tobacco use stood out as a top factor impacting aging, it was determined that maternal smoking during pregnancy accelerated epigenetic aging during the first years of childhood, as did parental smoking and indoor levels of black carbon (air pollution from partial fuel combustion).

The study also indicated two exposures that proved to have a protective effect against aging. They included the organic pesticide dimethyl dithiophosphate (DMDTP) and a persistent organic pollutant called polychlorinated biphenyl (PCB)-138.

Further research is needed to explain these results, but the former could be due to a higher intake of fruits and vegetables, said first author Paula de Prado-Bert, while the latter could be explained by its correlation with body mass index.

The results regarding smoking are in-line with other studies done on adults. The researchers believe the epigenetic modifications involved here most likely affect similar pathways for immune response, cell cycle, and detoxification, and therefore ultimately impact health from early life onward.

Although the study did have its limitations, like covering all variables of the exposome, it is a start to hopefully more studies that will provide convincing evidence to the dangers of certain toxins on childhood, especially smoking. Aging is a public health issue that everyone should be concerned about. So future research is needed to help drive government policy toward reducing environmental exposures and promote a healthy aging from the very start of life.

Source:Paula de Prado-Bert, et al. (2021).The early-life exposome and epigenetic age acceleration in children. Environment International.

Reference:Exposure to Tobacco Smoke in Early Life is Associated with Accelerated Biological Ageing. Barcelona Institute for Global Health (ISGlobal). August 26, 2021.

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Epigenetic Study Links Smoke Exposure in Early Life to Advanced Aging - WhatIsEpigenetics.com

Image by the National Cancer Institute on Unsplash

The following post was written and/or published as a collaboration between Benzingas in-house sponsored content team and a financial partner of Benzinga.

Salarius Pharmaceuticals Inc. (NASDAQ: SLRX) is developing a novel epigenetics-based treatment that targets the lysine-specific histone demethylase 1 (LSD1) enzyme, which researchers believe plays a key role in the growth of difficult-to-treat cancer cells. Salarius lead drug candidate, seclidemstat, has received Fast Track Designation, Orphan Drug Designation and Rare Pediatric Disease Designation for Ewing sarcoma from the U.S. Food and Drug Administration.

As Salarius works toward getting its pioneering new treatment to market as fast as possible, heres what Seclidemstat could mean for sarcoma patients and whats on the horizon for the company.

Sarcoma Patients Struggle with Aggressive Cancers and Limited Treatment Options

Ewing sarcoma is a rare and very deadly cancer that begins in a patients bones and primarily affects children and young adults.

While rare, there are about 500 new cases diagnosed in the United States each year. Of those, 40% will not respond to existing first-line treatments, which include chemotherapy, radiation, and surgery, to remove tumors from the bone. For those who dont see improvements with those first-line treatments or do but then relapse later on, as many as 90% will die within 5 years.

This high mortality rate paired with the fact that Ewing sarcoma primarily affects children and adolescents makes it an urgent priority for cancer researchers around the world.

Other sarcomas, while also rare, feature similar mortality rates and are often equally lacking in effective treatment options. With about 1,500 new cases of myxoid liposarcoma and FET-rearranged sarcomas in the U.S. each year, and a 5-year survival rate ranging from just 16% to 81% depending on how early the cancer was caught, Salarius hopes to get similar regulatory designations to facilitate seclidemstats development for the treatment of other sarcomas as well.

Story continues

As a treatment for Ewing sarcoma alone, Seclidemstat could generate an estimated $200 million in global sales annually, while hoping to significantly improving patient outcomes and quality of life. If approved for myxoid liposarcoma and FET-rearranged sarcoma as well, it could generate an additional $200 million per year.

Salarius Launches new Clinical Trials with Results Anticipated by 2022

Seclidemstat is currently being studied in 2 ongoing clinical trials as part of a treatment combination with chemotherapy agents. Salarius also expanded its clinical programs to study the LSD1 inhibitors potential to treat other sarcomas based on encouraging results from preclinical studies and early clinical trial data.

Going forward, the company is enrolling patients in a slate of new clinical trials set to begin later this year. That includes a clinical trial to study Seclidemstat in combination with Keytruda, an antibody-based drug manufactured by Merck & Co. Inc. (NYSE: MRK) to treat gynecological cancers.

Updates from Salariuss in-progress trials are expected to be announced in the 2nd half of this year with more robust data readouts planned to occur mid-next year. Updates from the trials the company is currently enrolling or planning to initiate soon are expected to be announced by the 2nd half of 2022.

For more information on Salarius, click here.

The preceding post was written and/or published as a collaboration between Benzingas in-house sponsored content team and a financial partner of Benzinga. Although the piece is not and should not be construed as editorial content, the sponsored content team works to ensure that any and all information contained within is true and accurate to the best of their knowledge and research. This content is for informational purposes only and not intended to be investing advice.

The author of this piece does not hold shares of any of the companies mentioned. Redington, Inc. employees and members of their families may from time own an equity interest in companies mentioned herein.

The preceding article is sponsored by the clinical communications unit of Redington, Inc, which is paid by Salarius Pharmaceuticals to provide investor communications services. The information contained in this article in no way represents investment advice or opinion on the part of Benzinga or its writers and is intended for informational purposes only.

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2021 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.

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Salarius Pharmaceuticals (SLRX) is Developing a Novel LSD1 Inhibitor, Positioning it as a Significant Mover in Epigenetics-Based Cancer Therapies -...

A2Z Market Research announces the release of Epigenetics Diagnostic Market research report. The market is predicted to grow at a healthy pace in the coming years. Epigenetics Diagnostic Market 2021 research report presents an analysis of market size, share, and growth, trends, cost structure, statistical and comprehensive data of the global market.

The top companies in this report include: Qiagen, Abcam plc, Novartis AG, Thermo Fisher Scientific, Inc., Roche Diagnostics, Eisai Co. Ltd., Active Motif, Merck, Illumina, Inc., Diagenode Diagnostics, Zymo Research Corporation, CellCentric, Valirx, .

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As analytics have become an inherent part of every business activity and role, form a central role in the decision-making process of companies these days is mentioned in this report. In the next few years, the demand for the market is expected to substantially rise globally, enabling healthy growth of the Epigenetics Diagnostic Market is also detailed in the report. This report highlights the manufacturing cost structure includes the cost of the materials, labor cost, depreciation cost, and the cost of manufacturing procedures. Price analysis and analysis of equipment suppliers are also done by the analysts in the report.

This research report represents a 360-degree overview of the competitive landscape of the Epigenetics Diagnostic Market. Furthermore, it offers massive data relating to recent trends, technological advancements, tools, and methodologies. The research report analyzes the Epigenetics Diagnostic Market in a detailed and concise manner for better insights into the businesses.

The report, with the assistance of nitty-gritty business profiles, project practicality analysis, SWOT examination, and a few different insights about the key organizations working in the Epigenetics Diagnostic Market, exhibits a point-by-point scientific record of the markets competitive scenario. The report likewise displays a review of the effect of recent developments in the market on markets future development prospects.

Global Epigenetics Diagnostic Market Segmentation:

Market Segmentation: By Type

ReagentsKitsInstrumentsEnzymesServices

Market Segmentation: By Application

OncologNon-oncology

Geographic analysis:

The global Epigenetics Diagnostic market has been spread across North America, Europe, Asia-Pacific, the Middle East and Africa, and the rest of the world.

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COVID-19 Impact Analysis

The pandemic of COVID-19 has emerged in lockdown across regions, line limitations, and breakdown of transportation organizations. Furthermore, the financial vulnerability Epigenetics Diagnostic Market is a lot higher than past flare-ups like the extreme intense respiratory condition (SARS), avian influenza, pig influenza, bird influenza, and Ebola, inferable from the rising number of contaminated individuals and the vulnerability about the finish of the crisis. With the rapid rising cases, the worldwide Epigenetics Diagnostic refreshments market is getting influenced from multiple points of view.

The accessibility of the labor force is by all accounts disturbing the inventory network of the worldwide Epigenetics Diagnostic market as the lockdown and the spread of the infection are pushing individuals to remain inside. The presentation of the Epigenetics Diagnostic makers and the transportation of the products are associated. If the assembling movement is stopped, transportation and, likewise, the store network additionally stops. The stacking and dumping of the items, i.e., crude materials and results (fixings), which require a ton of labor, is likewise vigorously affected because of the pandemic. From the assembling plant entryway to the stockroom or from the distribution center to the end clients, i.e., application ventures, the whole Epigenetics Diagnostic inventory network is seriously compromised because of the episode.

The research provides answers to the following key questions:

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Epigenetics Diagnostic Market to Witness Growth Acceleration | Qiagen, Abcam plc, Novartis AG, Thermo Fisher Scientific IMIESA - IMIESA

The Epigenetics-Based Kits Market research report systematicallyexplains each and every aspect related to the Global Epigenetics-Based Kits Market, which facilitates the reports reader to study and evaluate the upcoming market trend and execute the analytical data to promote the business.

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The growth trend forecasted on account of a thorough examination offers in-depth information regarding the Epigenetics-Based Kits Market. This global market report offers research and consulting services focused on achieving competitive leverage, with acquiring and preserving market position as key aims of the program.

Epigenetics-based kits market is expected to gain market growth in the forecast period of 2021 to 2028. Data Bridge Market Research analyses the market to grow at a CAGR of 12.90% in the above-mentioned forecast period.

Key Market Competitors Covered in the report:

Zymo Research; Active Motif, Inc.; Thermo Fisher Scientific Inc.; Promega Corporation; New England Biolabs; Agilent Technologies, Inc.; PerkinElmer Inc.; Bio-Rad Laboratories, Inc.; Shivom Ventures Limited; AsisChem Inc.; Enzo Life Sciences, Inc.; EpiGentek Group Inc.; BioVision Inc.; GeneTex, Inc. among others.(Customization Available)

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Key Pointers Covered in Epigenetics-Based Kits Market Industry Trends and Forecast

Important Features that are under offering & key highlights of the report:

What are the market factors that are explained in the report?

Market Dynamics:

The Epigenetics-Based Kits report also demonstrates the scope of the various commercial possibilities over the coming years and the positive revenue forecasts in the years ahead. It also studies the key markets and mentions the various regions i.e. the geographical spread of the industry.

Competitive Market Share:

The key players dominate the operations in the industry attributable to their strong geographical reach and huge production facilities. Players operating in this market are in intense competition in terms of technology, product development, innovation, and product pricing. To gain a competitive advantage over the other players in the Solvent Distillation Units industry, the leading players are focusing more on offering products at rational prices.

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Table Of Contents

Part 01: Executive Summary

Part 02: Scope of the Report

Part 03: Research Methodology

Part 04: Market Landscape

Part 05: Pipeline Analysis

Part 06: Market Sizing

Part 07: Five Forces Analysis

Part 08: Market Segmentation

Part 09: Customer Landscape

Part 10: Regional Landscape

Part 11: Decision Framework

Part 12: Drivers and Challenges

Part 13: Market Trends

Part 14: Vendor Landscape

Part 15: Vendor Analysis

Part 16: Appendix

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NEW YORK LXRepair and Gustave Roussy on Thursday said they have launched a joint laboratory to advance personalized cancer radiotherapy.

The new lab, dubbed Radio Care, will focus on advancing LXRepair's functional response prediction assays, which use DNA repair signals from blood or tumor samples to predict radiotherapy toxicity and patient responses. The biotech and cancer center, both in France, received funding from the country's National Research Agency's LABCOM program to launch the lab.

Within the partnership, Paris-based Gustave Roussy will contribute its radiotherapy expertise, while Grenoble, France-based LXRepair will utilize its in vitro assay platform. The predictive platform assesses functional signatures of DNA repair biomarkers in patients' blood and tumor samples using a biochip containing damaged DNA. Fluorescence analysis then reveals the interactions that occur at each damage site when the DNA repair enzymes from the patients' samples encounter the DNA on the chip. By analyzing the reactions, LXRepair claims its assay can characterize the efficiency and accuracy of patients' DNA repair mechanisms and predict their treatment response.

According to the firm, this approach is more "relevant and actionable" than genomic DNA repair assays, in part because it considers all possible molecular regulation, including epigenetics, transcription, and pathway reactivation, among other factors. It is developing the test to predict patients' responses to chemotherapy as well as radiation.

The firm is currently evaluating its functional assay prediction approach in several clinical studies, including one exploring biomarkers of radiotoxicity and another prospective trial focused on identifying biomarkers of radio-chemotoxicity and radio-chemoresistance among head and neck cancer patients.

LXRepair's tests are in the clinical validation phase for breast and prostate cancers, and one of the goals of the Radio Care lab's research will be to expand this approach to other tumor types.

"Making our assays available to oncologists for the global monitoring of a set of enzymatic biomarkers of DNA repair from a blood sample meets an important medical need," LXRepair President and CSO Sylvie Sauvaigo, said in a statement. "We have reached a turning point in the quest of radiotherapy personalization Radio Care is a unique opportunity to accelerate the shift to personalized radiotherapy and is a great honor."

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LXRepair, Gustave Roussy Ink Research Partnership in Personalized Radiotherapy - Precision Oncology News

J. Andrew Pospisilik, Ph.D.PORTLAND, Maine Van Andel Institutes J. Andrew Pospisilik, Ph.D., and Maine Medical Center Research Institutes Joseph Nadeau, Ph.D., have earned a five-year, $9.6 million Transformative Research Award from the National Institutes of Health to answer a set of questions that could fundamentally transform our understanding of health and disease: If you were born multiple times under the exact same circumstances, would you turn out to be the same person each time? And if not, what implications could the differences have for your health?

Although it may sound like science fiction, the answers could revolutionize our understanding of how probabilistic variation influences health before birth and throughout life and provide insights into new strategies for combating cancer, obesity and a host of other health concerns and diseases.

This groundbreaking research is made possible by a Transformative Research Award, part of the NIH Common Funds High-Risk, High-Reward Research Program. The award promotes cross-cutting, interdisciplinary approaches to projects that have potential to create new paradigms or challenge existing ones, according to NIH.

Joseph Nadeau, Ph.D.In some ways, our health is like a game of dice in which chance, or variation, plays a major role. We want to understand exactly how variation defines our health and how we can leverage it to combat disease, Pospisilik said. As scientists, were trained to see variation as error, but we believe that it is actually a necessary and vital biological regulatory process. We are grateful to the National Institutes of Health Common Fund for its support of this exciting project. These high-risk, high-reward funding mechanisms from the NIH are a rare opportunity to peek into the unknown to remind ourselves how little we actually know.

Variation is built into every species on earth and is thought to promote resilience against threats such as disease and environmental shifts. However, the genetic and epigenetic regulators that control variation have been difficult to identify and even more challenging to directly link to clinical outcomes.

Our genes and our environment are just 50% of what makes us who we are, Nadeau said. We want to understand what that other 50% is so that someday we may be able to predict whether early medical interventions or lifestyle changes could improve our chances for a healthy life.

Now, thanks to advances in technology and technique, Pospisilik, Nadeau and their collaborators will be able to detect and analyze the genetic and epigenetic factors that control variation patterns and link them to their effects.

To do so, they will leverage tools created by Nadeau and MMCRIs Christine Lary, Ph.D., (also a collaborator on the award) that allow scientists to identify molecular regulators of variation. Another team at VAI, led by Tim Triche, Jr., Ph.D., will support this effort to push current methodologies beyond their current limitations. Finally, teams lead by Ruth Loos, Ph.D., of the Icahn School of Medicine at Mount Sinai, David Carey, Ph.D., of Weis Center for Research at Geisinger, Neerja Karnani, Ph.D., of Singapore Institute for Clinical Sciences and Peter Gluckman, MBChB, MMedSc, M.D., FRS, of Singapore Institute for Clinical Sciences and University of Auckland will help place Pospisilik and Nadeaus novel discoveries into real-world, clinical context.By the end of the study, the team hopes to identify new sets of disease-related genes, delineate subtypes of disease, and better understand how the complex interaction between genetics and epigenetics impacts health.

Research reported in this publication was supported by the Office of the Director of the National Institutes of Health under award no.1R01HG012444 (Pospisilik and Nadeau). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

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ABOUT MAINE MEDICAL CENTER Maine Medical Center (MMC), recognized as a Best Regional Hospital by U.S. News and World Report for 2021-2022, is a complete health care resource for the people of Greater Portland and the entire state, as well as northern New England. Incorporated in 1868, MMC is the states largest medical center, licensed for 637 beds and employing more than 9,600 people. MMC's unique role as both a community hospital and a referral center requires an unparalleled depth and breadth of services, including an active educational program and a world-class biomedical research center. As a nonprofit institution, Maine Medical Center provides nearly 23 percent of all the charity care delivered in Maine. MMC is part of the MaineHealthsystem, a growing family of health care services in northern New England. For more information, visit http://www.mmc.org.ABOUT VAN ANDEL INSTITUTEVan Andel Institute (VAI) is committed to improving the health and enhancing the lives of current and future generations through cutting edge biomedical research and innovative educational offerings. Established in Grand Rapids, Michigan, in 1996 by the Van Andel family, VAI is now home to nearly 500 scientists, educators and support staff, who work with a growing number of national and international collaborators to foster discovery. The Institutes scientists study the origins of cancer, Parkinsons and other diseases and translate their findings into breakthrough prevention and treatment strategies. Our educators develop inquiry-based approaches for K-12 education to help students and teachers prepare the next generation of problem-solvers, while our Graduate School offers a rigorous, research-intensive Ph.D. program in molecular and cellular biology. Learn more at vai.org.

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Identical twins are a scientific enigma: No one knows why a fertilized human egg will sometimes split into two genetically identical embryosbut new research suggests that epigenetics have something to do with it.

Epigenetics is the study of how genes turn on or off depending on a persons behaviors and environment. Geneticists know that fraternal twins run in families, which suggests something in our DNA makes some people more likely to birth fraternal twins than others. But since identical twins happen more randomly, theres likely no genetic component.

To investigate whether epigenetics play a role in identical twin development, an international team of researchers analyzed the genomes of more than 6,000 individuals around the world, including identical twins, fraternal twins, and non-twin family members. They looked at 450,000 sites across their DNA to identify patterns of epigenetic differences, and found that identical twins had the same signature DNA tags at 834 points. This pattern was so consistent that an algorithm the team designed to look for those markers can reliably identify whether someone is an identical twin with up to 80 percent accuracy. The findings were published in Nature Communications.

You could think about these chemical epigenetic tags on DNA as molecular scars, said Baylor College of Medicine epigeneticist Robert Waterland to Science News. Waterland was not involved in the study, but he thinks its likely that the epigenetic markers are byproducts of the twin-splitting process.

[Related: These Australian twins are the second semi-identical pair ever reported]

That said, more work needs to be done. While it is possible that the DNA tags are a result of identical twinning, another theory is that it plays some role in causing it.

Why and how identical twins exist is really a mystery in developmental biology, senior author and biological psychologist at Vrije Universiteit Amsterdam, Dorret Boomsma, told Livescience.

About 12 percent of all human pregnancies begin as multiple pregnancies, but less than 2 percent actually yield birthed twins. The remaining 98 percent result in a vanishing twin, when one twin is miscarried and reabsorbed, according to a 1990 report in the International Journal of Fertility and Sterility. Sometimes that twin appears in an ultrasound before vanishing, but other times parents have no idea that they ever carried multiple embryos.

Analyzing peoples epigenomes and looking at their DNA tags could show whether or not someone had a vanished twin, which opens up a lot of avenues of inquiry, said Nancy Segal, a developmental psychologist at California State University at Fullerton who was not involved in the study, to Science News.

Identical twins are more likely to experience conditions like spina bifida, Beckwith-Wiedemann syndrome, and even left-handedness. Perhaps non-twins with these conditions stem from actually being an unknown identical twin, Segal said.

To properly determine whether the epigenetic changes are a cause or effect of an egg splitting in two will require experimenting with embryos and stem cells in the lab, and observing how development changes under different conditions, according to Deakin University twin researcher Jeffrey Craig in an interview with Science. But for now, the true confirmed cause of identical twinship is yet unknown.

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Epigenetics could reveal if you had a 'vanishing twin' - Popular Science