Category Archives: Epigenetics

Epigenetics Market research now available at Brand Essence Research encompasses an exhaustive Study of this business space with regards to pivotal industry drivers, market share analysis, and the latest trends characterizing the Epigenetics industry landscape. This report also covers details of market size, growth spectrum, and the competitive scenario of Epigenetics market in the forecast timeline.

The Epigenetics Market Report provides key strategies followed by leading Epigenetics industry manufactures and Sections of Market like- product specifications, volume, production value, Feasibility Analysis, Classification based on types and end user application areas with geographic growth and upcoming advancement. The Epigenetics market report provides comprehensive outline of Invention, Industry Requirement, technology and production analysis considering major factors such as Revenue, investments and business growth.

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The well-established players in the market are:

This report for Epigenetics Market discovers diverse topics such as regional market scope, product market various applications, market size according to specific product, sales and revenue by region, manufacturing cost analysis, Industrial Chain, Market Effect Factors Analysis, market size forecast, and more.

Drivers & Hindrances of the Epigenetics market: How does the report explicate on the same

The report unveils the driving parameters affecting the commercialization chart of this industry.

The Epigenetics market research report further illustrates the various challenges that this market is prone to as well as its impact on the market trends.

An important aspect that the report sets focus on is the market concentration ratio for the predicted timeframe.

The geographical spectrum of the business and its consequence on the Epigenetics market:

The report segments the Epigenetics market into USA, Europe, Japan, China, India, South East Asia depending on the regional scope of this business

Extensive data about the product consumption across innumerable sections as well as the valuation developed by these regions is also explained in the report.

The study puts emphasis on data concerning the consumption market share across these regions, as well as the market share attained by every region and product consumption growth rate.

Market segment by Type, the product can be split into

Market segment by Application, split into

Market segment by Regions/Countries, this report covers

North America (United States, Canada and Mexico)

Europe (Germany, UK, France, Italy, Russia and Turkey etc.)

Asia-Pacific (China, Japan, Korea, India, Australia, Indonesia, Thailand, Philippines, Malaysia and Vietnam)

South America (Brazil etc.)

Middle East and Africa (Egypt and GCC Countries)

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Key highlights and essential features of the report:

1) Which major players are presently listed in the report?Here are the companies that are presently listed in the report: Abcam Plc., Illumina, QIAGEN N.V., Merck & Co., New England Biolabs, Inc., Epizyme Inc., Thermo Fisher Scientific, Inc., Active Motif. Diagenode, Inc., and Zymo Research Corporation others.

**List of the firms stated above might differ in the final report dependent on a merger, name change, and other factors.

2) Can you list or add new firms as per our requirement?Yes,we can list or add new firm as per the requirement by client in the report. The final confirmation regarding the same must be provided by the research team subject to difficulty of survey.

**Availability of data will be confirmed after research in case of a privately held firm. Maximum 3 companies can be included at no additional charge.

3) Which all regional categorization are covered? Is it possible to add any specific country?Presently, our research report offers special focus and attention on the following areas:Europe, United States, Japan, China, India, Southeast Asia, and Central & South America

**Maximum one country of specific interest can be added at no extra charge. Charges will be applied for the addition of extra countries or regions.

4) Can the addition of extra Market breakdown or segmentation is possible?Yes, the addition of extra Market breakdown or segmentation is possibly dependent on the difficulty of survey and availability of data. On the other hand, detailed sharing of the requirements with our research team is a must before providing final confirmation to the client.

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Table of Content:

Market Overview:The report begins with this section where product overview and highlights of product and application segments of the global Epigenetics Market are provided. Highlights of the segmentation study include price, revenue, sales, sales growth rate, and market share by product.

Competition by Company:Here, the competition in the Worldwide Epigenetics Market is analyzed, By price, revenue, sales, and market share by company, market rate, competitive situations Landscape, and latest trends, merger, expansion, acquisition, and market shares of top companies.

Company Profiles and Sales Data:As the name suggests, this section gives the sales data of key players of the global Epigenetics Market as well as some useful information on their business. It talks about the gross margin, price, revenue, products, and their specifications, type, applications, competitors, manufacturing base, and the main business of key players operating in the global Epigenetics Market.

Market Status and Outlook by Region:In this section, the report discusses about gross margin, sales, revenue, production, market share, CAGR, and market size by region. Here, the global Epigenetics Market is deeply analyzed on the basis of regions and countries such as North America, Europe, China, India, Japan, and the MEA.

Application or End User:This section of the research study shows how different end-user/application segments contribute to the global Epigenetics Market.

Market Forecast:Here, the report offers a complete forecast of the global Epigenetics Market by product, application, and region. It also offers global sales and revenue forecast for all years of the forecast period.

Research Findings and Conclusion:This is one of the last sections of the report where the findings of the analysts and the conclusion of the research study are provided.

Appendix:Here, we have provided a disclaimer, our data sources, data triangulation, research programs, market breakdown and design, and our research approach.

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Epigenetics Market Size Analysis, Application Analysis, Regional Outlook, Competitive Strategies and Forecasts, 2019 To 2025 - The Market Stats News

9 December 2019

For the first time US researchers have shown that not only genetics but a different level of developmental regulation called epigenetics impacts the innate drive of mice to exercise.

Epigenetics is a molecular mechanism within cells that controls which genes are transcribed and which ones are not, determiningwhich genes are 'turned on'and which ones are 'turned off'.

In this study the scientists found that the methylation of DNA, a process which is known to 'turngenes off', in some neurons in the hypothalamus leads to a decrease in exercise activity.

Corresponding author, Dr Robert Waterland, professor at the USDA/ARS Children's Nutrition Research Centre at Baylor and Texas Children's Hospital said: 'We study developmental programming, which refers to how the environment during development can have a long term impact on risk of diseaseour earlier findings suggested that establishment of one's physical activity 'set point'can be affected by early environment, and that this may involve epigenetics.'

Epigenetics is more malleable than genetics and could potentially be altered to increase exercise activity. The scientists investigated a specialised class of neurons in the hypothalamus called AgRP neurons which regulate food intake.

They disabled a gene causing DNA methylation in the AgRP neurons of mice and then tested whether these changes in methylation altered the weight of the animals. Interestingly, they discovered that mice with the disabled gene were slightly heavier.

Intriguingly, the animals did not eat more food than the ones with unchanged DNA methylation. However, the researchers did find a major difference in spontaneous physical exercise. Measuring the distance that the mice ran on a running wheel showed that normal mice ran on average 6 kilometres per night, while the methylation-deficient ones only ran half as much, and thus lost less weight. Notably, the epigenetic changes seemednot to impact the physical ability of the animals to run, but the desire to exercise.

'Our findings suggest that epigenetic mechanisms, such as DNA methylation, that are established in the brain during fetal or early postnatal life, play a major role in determining individual propensity for exercise,'Waterland said. 'Nowadays, as decreases in physical activity contribute to the worldwide obesity epidemic, it is increasingly important to understand how all of this works.'

The work was published in Nature Communications.

Read more:
'Couch potato' mice reveal that epigenetics affects urge to exercise - BioNews

Konstantinos Tzelepis, PhD, presented award-winning abstract on METTL3

CAMBRIDGE, England, Dec. 9, 2019 /PRNewswire/ -- STORM Therapeutics, the biotechnology company focused on the discovery of small molecule therapies modulating RNA epigenetics announces today, that its collaborator Dr. Konstantinos Tzelepis, Sir Henry Wellcome Fellow and visiting scientist at the Wellcome Sanger Institute, received the ASH-BSH Abstract Achievement Award for his work on STORM Therapeutics' lead programme, METTL3, at the 61st Annual Meeting of the American Society of Hematology (ASH) held on 7th-10th December 2019 in Orlando, Florida.

Dr. Tzelepis received the meritorious award for his abstract entitled 'Pharmacological Inhibition of the RNA m6a Writer METTL3 As a Novel Therapeutics Strategy for Acute Myeloid Leukemia'at the Abstract Achievement Award Ceremony which was held on Saturday, 7th December 2019 at 3:30pm (EST) at the Orange County Convention Center in Exhibit Hall B2-B4.

Dr. Tzelepis's work, which was carried out in collaboration with the Wellcome Sanger Institute and the University of Cambridge, was presented in an oral presentation during the "802. Chemical Biology and Experimental Therapeutics: Novel Compounds and Mechanisms of Action" session on Sunday, 8th December 2019 at 9:30am-11:30am (EST) at the Orange County Convention Centre. The abstract and talk encapsulated the ground-breaking work made on targeting RNA modifying enzymes for cancer treatment and described the recent progress made with the METTL3 inhibitor.

STORM has identified small molecule inhibitors of METTL3 that are orally bioavailable and show pronounced anti-tumour efficacy in physiologically relevant, proof of concept animal models of Acute Myeloid Leukaemia (AML). The talk demonstrated that small molecule inhibition of METTL3 produces the same phenotype and effects previously described in one of STORM's founder scientists' publications using genetic models and validates METTL3 as a druggable target for cancer.

Keith Blundy, CEO of STORM Therapeutics, said:"STORM is progressing fast in its preclinical work with our multiple programmes to showcase the capabilities of our novel platform. STORM is a pioneer in RNA epigenetics and we are very pleased to hear that our collaborator is being recognized for the partnership research of METTL3. As the first company in the world to demonstrate in vivo activity of an RNA methyltransferase inhibitor, we are excited to be leading the field as we look to develop these highly innovative new treatment options for cancer patients."

About STORM

STORM Therapeutics, founded in 2015, is a University of Cambridge spin-out translating the ground-breaking work of Professors Tony Kouzarides and Eric Miska in RNA epigenetics into the discovery of first-in-class drugs in oncology and other diseases. Storm is the leading company tackling disease through modulating RNA modifying enzymes and is developing a unique platform and pipeline to address these enzyme classes, including RNA methyltransferases.

STORM is backed by blue chip investors Cambridge Innovation Capital, M Ventures, Pfizer Ventures, Taiho Ventures LLC, Seroba Life Sciences and IP Group, who share the team's ambitions to build a world-leading company in the field.

The Wellcome Sanger Institute

The Wellcome Sanger Institute is a world leading genomics research centre. We undertake large-scale research that forms the foundations of knowledge in biology and medicine. We are open and collaborative; our data, results, tools and technologies are shared across the globe to advance science. Our ambition is vast we take on projects that are not possible anywhere else. We use the power of genome sequencing to understand and harness the information in DNA. Funded by Wellcome, we have the freedom and support to push the boundaries of genomics. Our findings are used to improve health and to understand life on Earth. Find out more at http://www.sanger.ac.uk or follow us on Twitter, Facebook, LinkedIn and on our Blog.

SOURCE STORM Therapeutics

Excerpt from:
STORM Therapeutics' Collaborator Awarded ASH-BSH Abstract Achievement Award at the 61st ASH Annual Meeting & Exposition - PR Newswire UK

The Epigenetics Market report contains wide-extending factual assessment for Epigenetics, which enables the customer to separate the future complicity and estimate right execution. The advancement rate is evaluated dependent on insightful examination that gives the credible information on the worldwide Epigenetics market. Imperatives and advancement points are merged together after a significant comprehension of the improvement of Epigenetics market. The report is all around made by considering its essential information in the overall Epigenetics market, the essential components in charge of the interest for its products and administrations. Our best analysts have surveyed the Epigenetics market report with the reference of inventories and data given by the key players(Abcam, Novartis, Roche, Active Motif, Inc., Agilent Technologies, Inc., Bio-Rad Laboratories, Diagenode, Inc., Illumina, Merck & Co., Inc., Thermo Fisher Scientific, New England Biolabs, Inc., Perkinelmer, Inc., Qiagen N.V., Thermo Fisher Scientific, Inc., Zymo Research Corp.), flexible sources and records that help to upgrade cognizance of the related methodological conditions.

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The Epigenetics market report shows a point by point division (Kits, Reagents, Enzymes, Instruments) of the overall market reliant on development, product type, application, and distinctive techniques and systems. The point-to-point elucidation of the Epigenetics market's assembling system, the usage of advancement, conclusions of the world market players, dealers and shippers' order, and the explicit business data and their improvement plans would help our customers for future courses of action and movement planned to make due in the Epigenetics market.

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Research Objective :

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Global Epigenetics Market Growth 2019-2025 Abcam, Novartis, Roche, Active Motif, Inc., Agilent Technologies, Inc. - Exclusive Industry Reports

You may have your new years resolutions sorted but following through with your most ambitious fitness goals could be down to genetics.

By Mike Huyhn

Posted on December 6, 2019

Talk about a rude awakening. As another new year rounds the bend there are no doubt plenty of people plotting their annual fitness goals which they will never actually fulfil. You hopeful tragics get an A for effort.

Have you ever wondered though why its easier for the dedicated gym junkies to lift, run, bike and swim on a regular basis whilst others find it hard to get off the couch at all?

Researchers from the Baylor College of Medicine did and thats why they conducted a study to find out why this distinction in motivational behaviour between the dedicated and the lazy existed. The results from the study found that its not really your fault if you cant be bothered gyming its all in your genes.

The research entitled DNA methylation in AgRP neurons regulates voluntary exercise behaviour was published in Nature Communications. It highlights the epigenetic control of the expression of certain genes. These particular epigenetic mechanisms are explained to be more malleable than pure genetics alone, suggesting that there is still a way to program people into being more physically driven rather than just blaming genetics.

How they reached this conclusion was through the creation of an epigenetic couch potato mouse. In this test subject, the researchers analysed changes in the DNA methylation in neurons within the hypothalamus. Basically science jargon which says they found a link between the couch potato mouse and voluntary exercise behaviour.

Our earlier findings suggested that establishment of ones physical activity set point can be affected by early environment, and that this may involve epigenetics, explained corresponding author Robert A. Waterland, PhD, professor of pediatrics nutrition at the USDA/ARS Childrens Nutrition Research Center at Baylor and Texas Childrens Hospital.

Further investigations were conducted to test whether DNA methylation in the brain affects energy balance. Researchers implemented running cages in the animals cages for eight weeks and observed the difference between two specific groups. The normal male mice ran approximately 6km every night whilst the mice with a specific gene blocked only ran half the distance. Naturally the latter group also lost less fat.

What the researchers concluded from the experiment was that the gene-deficient mice were capable of running the same distance as normal mice but simply lacked the desire to.

Our findings suggest that epigenetic mechanisms, such as DNA methylation, that are established in the brain during fetal or early postnatal life, play a major role in determining individual propensity for exercise, Waterland said.

Nowadays, as decreases in physical activity contribute to the worldwide obesity epidemic, it is increasingly important to understand how all of this works.

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Researchers discover why youre skipping the gym for Netflix and sleep - The CEO Magazine

Epigenetics, or the study of biological changes that occur due to different chemical marks that alter the expression of our genes, proves that the beneficial effects of yoga penetrate deep into our minds and bodies and may even touch the very code of life that makes us who we are.

Do you feel stressed too often? Dont worry, youre not alone. The growing number of mentalhealth cases in India are pointing in the direction of a pressing need for attention. Research hasfound the top few sources of increasing stress in the lives of over one billion Indians to be money,work, family responsibilities, and health concerns.

Too much stress can take a significant toll on ones health. Not being able to copewith stress can lead to chronic diseases and accelerated ageing (but dont think about that toomuch, or risk adding it to your already lengthy list of issues inducing stress). If you have been trying to takemeasures to reduce therapy and have not achieved the desired outcome, there is still hope.

Epigenetic research has found that the ancient art of meditation, particularly mindfulmeditation, has numerous health and stress-reducing benefits.Yoga is the most ancient form of basic human wellness or unity of mind-body or in biologicalterms state of homoeostasis Homeo (resembling) stasis (equilibrium). In this state, all chemicalsand biochemicals in the body are in absolute balance state. All hormones calibrated (no excess orlittle testosterone, estrogen, cortisol), no excess or little adrenaline, dompamine(feel good) purged of all environmental toxins. Yoga helps in rhythmicbreathing which allows mind-body calibration resulting inneuroplasticity that fine tunes the brain or CNS to get calmer.

(The author isfounder,Vantage Enterprise)

More:
Get to the core with epigenetics - Deccan Herald

One dog year is not equivalent to seven human years, despite widespread use of the ratio for calculating the age of canine companions. Presumably, the ratio is based on the average lifespan of dogs being 10 years and humans being 70 years, its not quite so simple. The formula is not based on any real science and it was debunked by veterinarians years ago.

But geneticists digging into the mysteries of aging have developed a new calculation to understand how our canine companions' ages correspond to our own.

Calculate

(*Only enter numbers greater than zero)

Your dog's age in human years is:

To understand how dogs age, the team looked at a phenomenon called DNA methylation. As mammals get older, their DNA picks up methyl groups that "stick" to their DNA. While these groups dont change the DNA itself, they attach to the genetic molecule and can turn certain genes on or off, which is an important part of epigenetics, or the way environmental factors cause certain genes to express themselves.

Methlyation occurs at a relatively steady rate as humans age, which allows researchers to estimate a person's age, a process theyve dubbed the epigenetic clock.

In the new paper on dog years, which has yet to be peer reviewed and is currently posted on the preprint server bioRxiv, a team led by Tina Wang of the University of California, San Diego, compared the epigenetic clocks in people to canines to better understand the genes associated with aging. They picked dogs because most live in the same environments as humans and also receive some degree of medical care, like humans do.

The team looked at methylation rates in 104 Labrador retrievers between the ages of four weeks and 16 years old, reports Michelle Starr at Science Alert. They then compared them to published methylation profiles of 320 humans from age one to 103. (They also compared both to 133 mice methylation profiles.)

It turns out some parts of a dogs life follows the same pattern as humans, though other longevity milestones dont link up quite as nicely. For instance, the methylation rate showed a seven-week-old pup corresponds to a 9-month-old human baby, and both species begin to get their first teeth at this time.

But the comparison breaks down after early puppyhood. The dog clock ticks much faster with pups speeding through puberty and reaching sexual maturity within their first year. Then, the dog's epigenetic clock slows down as the dog ages, and begins to match up with humans again in its later years.

Overall, the average 12-year lifespan of a Labrador lined up with the average worldwide lifespan of humans, which is about 70 years.

While the study complicates the concept of dog years, it does show that the animals experience similar methylation processes as humans.

We already knew that dogs get the same diseases and functional declines of aging that humans do, and this work provides evidence that similar molecular changes are also occurring during aging, Matt Kaeberlein, a biogerontologist at the University of Washington who was not involved in the study, tells Virginia Morell at Science. Its a beautiful demonstration of the conserved features of the epigenetic age clocks shared by dogs and humans.

The new formula for a dogs ages based on the study requires a little more math than multiplying by seven. You multiply the natural logarithm of a dog's age by 16, then add 31 [human_age = 16ln(dog_age) + 31].

According to the formula, a 2-year-old dog is the equivalent of a 42-year-old human, but things slow down after that. A 5-year-old dog is the equivalent of a 56.75 year old human, and a 10-year-old dog is the equivalent of 67.8-year-old person.

Evolutionary biologist Steve Austad of the University of Alabama in Birmingham, who was not involved in the study, tells Morell that hes not too surprised that the epigenetic clock applies to dogs, too. He says that by studying different dog breeds with different lifespans the researchers may find some interesting results.

This formula is not the last word on dog years, however, especially since it only looked at one breed. Erika Mansourian, writing for the American Kennel Club, reports that the American Veterinary Medical Association says the accurate way to calculate dog years for a medium-sized dog is to assume the first year is equivalent to 15 years and age two adds another nine years. After that, each year of a dogs life is equivalent to five human years. It doesn't perfectly line up with the new formula, but both acknowledge that dogs age rapidly in their first years of life.

Whatever the case, dogs lives are all too short. That may be why people are excited about a project by the Dog Aging Project, which is currently recruiting 10,000 pets and their owners to participate in a new study that will look at the dogs' health, gut microbes, diet and exercise to understand aging. And 500 lucky dogs will test out a new drug that may help slow the aging process, which could help us someday, too.

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Calculate Your Dog's Age With This New, Improved Formula - Smithsonian.com

Through early adulthood, exposure to new experienceslike learning to drive a car or memorizing information for an examtriggers change in the human brain, re-wiring neural pathways to imprint memories and modify behavior. Similar to humans, the behavior of Florida carpenter ants is not set in stonetheir roles, whether it is protecting the colony or foraging for food, are determined by signals from the physical and social environment early in their life. But questions remain about how long they are vulnerable to epigenetic changes and what pathways govern social behavior in ants.

Now, a team led by researchers in thePerelman School of Medicine discovered that a protein called CoREST, a neural repressor that is also found in humans, plays a central role in determining the social behavior of ants. The results, published inMolecular Cell, also revealed that worker ants called Majors, known as brawny soldiers that protect colonies, can be reprogrammed to perform the foraging rolegenerally reserved for their sisters, the Minor antsup to five days after they emerge as an adult ant. However, the reprogramming is ineffective at the 10-day mark, revealing how narrow the window of epigenetic plasticity is in ants.

How behavior becomes established in humans is deeply fascinatingwe know its quite plastic especially during childhood and early adolescencehowever, of course, we cannot study or manipulate this experimentally, saysthe studys senior authorShelley Berger, the Daniel S. Och University Professor in the departments of Cell and Developmental Biology and Biology, and director of the Penn Epigenetics Institute. Ants, with their complex societies and behavior, and similar plasticity, provide a wonderful laboratory model to understand the underlying mechanisms and pathways."

Read more at Penn Medicine News.

See more here:
Reprogramming ant 'soldiers' - Penn: Office of University Communications

The Epigenetics Market report includes the research on production, consumption, revenue, CAGR, market share and growth rate, and forecast (2013-2023) of the major players.

Global Epigenetics Market Report helps the readers to maximize their profits and business making ventures by gaining complete insights of Epigenetics Industry. The latest developments and growth opportunities in Epigenetics market are covered. Development trends, revenue analysis, Global Epigenetics market share and market dynamics are presented to optimize the business. The vital Epigenetics insights, opportunities in existing and emerging segments are explained. An in-depth analysis of the present state of Epigenetics, progressive future trends, and comprehensive analysis based on Epigenetics type, application, players and regions are covered. The report thoroughly analyzes the Epigenetics competitors, SWOT analysis, industry chain structure and production process view.

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The top Epigenetics industry players are:

Major Players in Epigenetics market are:

RocheMerck & Co. Ltd.QiagenCellcentric LimitedValirx PlcThermo Fisher ScientificSigma-Aldrich CorporationEisai Co. Ltd.Oncoloys Biopharma Inc.AbcamDiagenodeSyndex PharmaceuticalsActive Motif Inc.Chroma TherapeuticsZymo Research CorporationIllumina IncNovartis AG

The report begins with an introduction, definition, objectives, and Global Epigenetics market scope. The industry size is estimated based on market value, revenue, concentration ratio and Epigenetics growth rate. The report covers major industry trends, drivers, threats which will depict the market growth during the forecast period. The complete perspective in terms of Epigenetics revenue, geographical regions namely North America, Europe, Asia-Pacific, Middle-East & Africa, and South America is portrayed. The key information on distributors and suppliers of Epigenetics industry represents the present and forecast trends.

A complete market tactics are explained in this research report which is segmented into by product type, end users, applications, etc. Forecast industrial statistics will roll on the way to predict the futuristic industry growth opportunities. The pertinent facts and market numbers are presented which are gathered from regulatory authorities. Dominating factors influencing the growth of dominant market players and their position is analyzed in this report.

Global Epigenetics Industry news, plans & policies, market drivers, analysis of upstream raw material suppliers and downstream buyers of Epigenetics is carried out in this report. On regional and country level market share, production value, gross margin analysis, consumption ratio, import-export scenario, and SWOT analysis is covered. Global Epigenetics business forecast study enlists the market price (in USD) and volume forecast for every region, product kind, and applications.

The business approach and growth statistics implemented by Global Epigenetics industry competitors will lead to a competitive edge in the industry. The production and demand statistics of Epigenetics driven by evolving market segments across different regions, type and application are mentioned in this report. The value chain analysis and market share for varied Epigenetics players are covered. The consumption statistics for the mentioned type, applications and regions are enclosed in the report. This report will help you in analyzing the industry scenario and characteristics of Global Epigenetics market.

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Detailed analysis of segment and subsegment are given below

Types of Global Epigenetics Industry:

DNA MethylationHistone MethylationHistone AcetylationLarge Noncoding RNAMicroRNA ModificationChromatin Structures

Applications of Global Epigenetics Industry:

OncologyNon-OncologySolid TumorsLiquid TumorsInflammatory DiseasesMetabolic DiseasesInfectious DiseasesCardiovascular Diseases

The Epigenetics market competitive factors leading to heavy market demand and development scope is analyzed thoroughly. Also, a special focus on distributors, manufacturers, traders, and suppliers is provided. The market share, units produced and consumption in every consecutive year is obtained from this research report. All the latest qualitative and quantitative information along with sales data are presented. Also, the detailed analysis of past performance of Global Epigenetics Industry and business-related moves with the present scenario is studied.

Report Summary:

In the first section, the Epigenetics Market report presents industry overview, definition, and scope. The second part briefs about the Epigenetics industry bifurcation by Type, Application and Geographical regions. The major market players of Epigenetics Industry and their market share, revenue analysis, sales margin, etc. are presented in this in depth analysis. The Export-Import policy, resources utilized, raw materials study, demand and supply of the products is offered for the better understanding of new entrants and their market position is explained. The Strength, Weakness, Opportunity & Threats are analyzed in such a manner that it will be helpful for future decision making processes. The Porters Five Force analysis is examined along with the 5-year forecast scope of the report for Epigenetics industry. All these will lead to successful & profitable business plans and informed moves. Additionally, the sources of research, research processes, findings, conclusions are offered.

Why Select This Report:

Complete analysis on market dynamics, market status, and competitive Epigenetics view is offered.

Forecast Epigenetics Industry trends will present the market drivers, constraints and growth opportunities.

This research report will help to understand how the market will grow in the coming years lets say next 5-6 years and so on.

All vital Epigenetics Industry verticals are presented in this study like Product Type, Applications and Geographical Regions.

This in-depth market study will help to analyze the and take informed decision in their respective field.

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Global Epigenetics Market CAGR, Share and Growth Rate, and Forecast (2013-2023) of the Industry Major Players. - Montana Ledger

Theres no shortage of data highlighting how humans have impacted their environment. From climate change to Feng Shui, people constantly alter their surroundings to suit their needs. What is less understood is how environment can impact human development.

In Vitro Fertilization (IVF) gives many hopeful parents the opportunity to create a family. With the use of donor eggs, hopeful parents-to-be often assumed that the child wouldnt share any of their characteristics. However, with the development of epigenetics, this isnt altogether true.

Epigenetics is the study of how lifestyle choices can impact your DNA, while not actually changing it. External factors can include environment, what we consume, how we are raised and even how we feel about our world. If we think about a DVD, we cant alter the content, but we can adjust the picture, language preferences, volume settings, etc. Through the lens of IVF with donor eggs, epigenetics observes how non-genetic characteristics (or markers) can be transmitted from parent to offspring.

Stress, exercise, proper nutrition during pregnancy, the general health status of both partners, these are all factors that can affect how your babys genes are expressed, Carrie Nicols, organic farmer and student of holistic nutrition tells Parentology. Even if you use donor eggs, your biography can inform your childs biology.

What does expression mean? Nicols likens the process to light switches. Certain characteristics can be turned on or off depending on the stimuli, she says. Once we know what triggers them proper nutrition for example we can figure out how to manipulate them for better overall health.

If epigenetics has the potential to alter or affect health conditions such as obesity, diabetes and even psychiatric illness, it stands to reason physical and hormonal changes that occur during pregnancy would certainly be impacted. In 2009, researchers at the University of Pittsburgh Medical Center suggested our social environment, including maternal care, can induce epigenetic changes.

Nicols agrees. While factors such as nutrition, stress and hormones wont change your genetic code directly, they can certainly leave an imprint to pass along to your children.

The impact of environment on an embryo in utero cant be overstated. Researchers studied the effects of malnutrition on women and the children they produced between 1944 and 1945. Not surprisingly, mothers with limited access to food produced underweight babies.

What was surprising was that those babies grew up to have underweight babies, even after the effects of food insecurity were felt. Of those babies that survived, malnutrition had changed a marker in their genetic code, leading researchers to determine that the nine months in utero were the most important period in determining how much or how little genetic activity genes will produce during a persons life.

If a woman is undergoing IVF using donor eggs, this argument proves particularly relevant. Dr. Norbert Gleicher, Medical Director and Chief Scientist at the Center for Human Reproduction (CHR) in New York, agrees. While (women) do not contribute maternal genes to the baby, they determine, in very significant ways, how these genes will work during the individuals lifetime, he tells Parentology.

Moreover, Gleicher says a womans impact on her embryo while its in utero not only affects her unborn child. Maybe even more importantly, (genes that are) programmed during the in utero period can also be inherited into future generations. Therefore, you may be important not only for how your own childs genes function, but also how your grandchilds genes will be functioning, even if you used donor eggs.

Ultimately, pregnancy demands a change in your lifestyle. Regardless of whether you have IVF using donor eggs or conceive naturally, the incentive to eat well, rest and take care of yourself is paramount to the health and well-being of your child.

Your IVF JourneyCenter for Human ReproductionBio News UK

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Nurture vs Nature: Epigenetics, IVF and the Donor Egg - Parentology