StudyFinds Blotter: Other Notable Health Research From April 28, 2022 – Study Finds

Heres a look at other notable health studies, innovations and research from around the world. Links will take you to press releases or journal entries.

Researchers Identify Specific Genes that Play Key Role in SchizophreniaSchizophrenia is a serious psychiatric disorder that starts in late adolescence or early adulthood and affects around 1 in 300 people worldwide, according to the World Health Organization.

Inflammasome activation in infected macrophages drives COVID-19 pathologySevere COVID-19 is characterized by persistent lung inflammation, inflammatory cytokine production, viral RNA, and sustained interferon (IFN) response all of which are recapitulated and required for pathology in the SARS-CoV-2 infected MISTRG6-hACE2 humanized mouse model of COVID-19 with a human immune system.

Cancer cells use self-inflicted DNA breaks to evade growth limits imposed by genotoxic stressGenotoxic treatments, such as radiation and some chemotherapy drugs, are a mainstay of cancer therapy, but they often fail to fully destroy tumor cells.

Unlocked Enzyme Structure Shows How Strigolactone Hormone Controls Plant GrowthAs sessile organisms, plants have to continually adapt their growth and architecture to the ever-changing environment.

P-wave and S-wave response of coal rock containing gas-water with different saturation: an experimental perspectiveThe acoustic response of gas and/or water saturated coal rock is fundamental for establishing the correspondence between the physical properties of the coal reservoir and the characteristics of the well-logging response, which is the technology essential for the geophysical exploration of coalbed methane (CBM).

Lipofilling procedure improves pain and function in finger osteoarthritisFor patients with painful finger osteoarthritis, a nonsurgical procedure called lipofilling in which fat obtained from another part of the body is transferred into the arthritic joints produces lasting improvements in hand function and especially pain, suggests a study in the May issue ofPlastic and Reconstructive Surgery,the official medical journal of theAmerican Society of Plastic Surgeons(ASPS).

Neural pathway key to sensation of pleasant touch identifiedStudying mice, scientists at Washington University School of Medicine in St. Louis have identified a neural circuit and a neuropeptide a chemical messenger that carries signals between nerve cells that transmit the sensation known as pleasant touch from the skin to the brain.

Engineers at UBC get under the skin of ionic skinIn the quest to build smart skin that mimics the sensing capabilities of natural skin, ionic skins have shown significant advantages.

Higher COVID-19 Death Rates in the Southern U.S. Due to Behavior DifferencesDuring the pre-Omicron phases of the COVID-19 pandemic, regions of the U.S. had markedly different mortality rates, primarily due to differences in mask use, school attendance, social distancing and other behaviors.

Rabies shows how scale of transmission can enable acute infections to persist at low prevalenceRabies is a deadly zoonotic disease that causes tens of thousands of deaths every year, mainly among African and Asian children.

Predictive metabolic networks reveal sex- andAPOEgenotype-specific metabolic signatures and drivers for precision medicine in Alzheimers diseaseLate-onset Alzheimers disease (LOAD) is a complex neurodegenerative disease characterized by multiple progressive stages, glucose metabolic dysregulation, Alzheimers disease (AD) pathology, and inexorable cognitive decline.

High-Frequency Spinal Cord Stimulation Shows Improved Longer Lasting Pain ReliefSpinal cord stimulation (SCS) for chronic pain involves delivering low levels of electricity directly into the spinal cord using an implanted device, which modifies or blocks nerve activity to minimize the sensation of pain reaching the brain.

Nemours Childrens Health Researchers Awarded $10.9 Million NIH COBRE Grant Supporting Work Well Beyond MedicineThe National Institutes of Health (NIH) recently awarded a Phase 1, 5-year $10.9 million Center of Biomedical Research Excellence (COBRE) award, entitled Research Expanding Access to Child Health (REACH) Center to Anne Kazak, PhD, Enterprise Director, and Melissa Alderfer, PhD, Director of the Center for Healthcare and Delivery Science (CHDS) at Nemours Childrens Health.

Understanding Black griefThe average life span for Black Americans is 78 years six years shorter than it is for white Americans. Compared with white Americans, Black Americans are twice as likely to die of heart disease, 50% more likely to have high blood pressure and are likelier to die at earlier ages of all causes.

Viewing a Microcosm Through a Physics LensWhat can physics offer biology? This was howAlison Patteson, assistant professor in the College of Arts and Sciences physics department and also a faculty member in theBioInspired Institute, began the explanation of why her physics lab was studying bacteria.

CAR T drives acute myeloid leukemia into submission in pre-clinical studiesMassachusetts General Hospital (MGH) researchers have developed a novel treatment strategy that has the potential to bring the life-saving benefits of chimeric antigen receptor T-cell therapy (CAR T) to patients with acute myeloid leukemia (AML) the most common form of leukemia in adults.

Tufts Researchers Discover New Function Performed by Nearly Half of Brain CellsResearchers at Tufts University School of Medicinehave discovered a previously unknown function performed by a type of cell that comprises nearly half of all cells in the brain.

Study exhibits sleep deprivation impairs stem cells within the corneaSleep deprivation, which implies getting too little high-quality sleep, is a critical well being downside.

Historic Redlining and Contemporary Behavioral Health Workforce DisparitiesAs the nation continues to confront the lasting legacy of Jim Crowera structural racism, attention is increasingly turning to the association between historical redlining policies and contemporary racial disparities in access to health care, including behavioral health.

Gut microbiome could alter response to most cancers remedySince historic instances, our intestine microbiome, dwelling to an unlimited variety of micro organism, viruses, fungi, and different microorganisms, has been thought to affect many facets of human well being.

Researchers Share Insights about Mechanisms of Human Embryo and Create Method to Develop Transcriptionally Similar Cells in Tissue CultureBlood-forming stem cells found in bone marrow are the life-saving component used in bone marrow transplants.

Seven hours of sleep is optimal in middle and old age, say researchersSeven hours is the ideal amount of sleep for people in their middle age and upwards, with too little or too much little sleep associated with poorer cognitive performance and mental health, say researchers from the University of Cambridge and Fudan University.

Stanford scientists found that free-living runners default to an energy-saving speed, no matter the distanceStanford University scientists have found that when recreational runners are left to their own devices and outfitted with a wearable fitness tracker, they prefer to run at the same calorie-saving pace, regardless of the distance ran contrary to the explicit goals of competitive racing.

Historic Redlining and Contemporary Behavioral Health Workforce DisparitiesAs the nation continues to confront the lasting legacy of Jim Crowera structural racism, attention is increasingly turning to the association between historical redlining policies and contemporary racial disparities in access to health care, including behavioral health.

New Article Outlines the Characteristics of a Longevity DietExamining a range of nutrition research from studies in laboratory animals to epidemiological research in human populations provides a clearer picture of the best diet for a longer, healthier life, said USC Leonard Davis School of Gerontology professorValter Longo.

Study tracks COVID-19 infection dynamics in adultsA team led by scientists at the University of Illinois Urbana-Champaign tracked the rise and fall of SARS-CoV-2 in the saliva and nasal cavities of people newly infected with the virus.

Humans run at the most energy-efficient speed, regardless of distanceAs race season approaches, many runners have the same goal: go faster. But in a study publishing April 28 in the journalCurrent Biology, researchers show that speeding up might require defying our natural biology.

Not All Dietary Fibers Are Equal: Heres WhyThats according to anew studyTrusted Sourcein which researchers found that the benefits of fiber can depend on the type of fiber, the amount of fiber, and the individual consuming the fiber.

Combination of weak muscles and abdominal obesity can be an early sign of functional decline in menA study conducted at the Federal University of So Carlos (UFSCar) in Brazil suggests that early detection of functional decline the dwindling capacity to perform everyday tasks independently is possible by observing patients as they engage in simple actions such as sitting down and getting up from a chair, standing still, and walking a short distance.

Changing Guidelines for Treating Mild Chronic Hypertension in PregnancyA study published this month in theNew England Journal of Medicineproves through a large clinical trial that treating high blood pressureeven mild casesduring pregnancy is safe and beneficial for both mother and developing baby.

New report calls on bioethics to take a stand against anti-black racismA new Hastings Center special report calls on the field of bioethics to take the lead in efforts to remedy racial injustice and health inequities in the United States.

Mother and child vulnerable to endocrine disruptor exposureThey can be found in cosmetics, plastic containers, furniture, toys, or baby bottles. Endocrine disruptors, molecules disrupting our hormones, are everywhere in our daily lives.

Supporting school-community collaboration for the implementation of a multi-tiered school mental health program: The Behavioral Health Team modelInvesting in school mental health programs has the potential to improve youths access to mental health services.

Inclusive Design and Research Methods Will Lead To More Innovative, Intelligent TechnologyThat observation is at the heart of her latest research exploring how older Black adults in lower income environments feel about asking health questions, how they pose those questions verbally, and whether voice assistant devices respond as expected.

From Blurry to Bright: AI Tech Helps Researchers Peer into the Brains of MiceJohns Hopkins biomedical engineers have developed an artificial intelligence (AI) training strategy to capture images of mouse brain cells in action.

MD Anderson and Community Health Network announce partnership to create fully integrated cancer programThe University of Texas MD Anderson Cancer Centerand Indianapolis-based Community Health Networktoday announced a partnership agreement to create Community Health Network MD Anderson Cancer Center.

Improving mental health in Multiple Sclerosis with an interpersonal emotion regulation intervention: A prospective, randomized controlled trialOver a third of people with Multiple Sclerosis (PwMS) struggle with poor mental health, which exacerbates physical symptoms and complicates clinical treatment.

Vaccination campaign messages often prove ineffectiveA study in eight European countries shows that information on the benefits of vaccines can even reduce the willingness to get immunized.

Online health and wellbeing program using singing techniques can improve quality of life and breathlessness after COVID-19There are few evidence-based interventions for long COVID; however, holistic approaches supporting recovery are advocated.

A complete ban on all smoking would not improve healthy life expectancy for 40 yearsThe negative impact of smoking on health inequalities in the UK means even if smoking stopped tomorrow, the full health benefits would not be seen until 40 years down the line.

UTHealth Houstons UTMOVE program receives distinguished Edmond J. Safra Fellowship in Movement DisordersUTHealth Houstons Movement Disorders and Neurodegenerative Diseases Fellowship Training Program (UTMOVEfellowship program) has been chosen byThe Michael J. Fox Foundation for Parkinsons Research(MJFF) as one of eight international academic centers to train a new movement disorder clinician-researcher a neurologist with additional training and expertise in diagnosing and treating Parkinsons and related diseases as part of the Edmond J. Safra Fellowship in Movement Disorders Class of 2025.

More than a million smokers likely to quit after U.S. bans menthol cigarettesA new study projects that a U.S. ban on menthol cigarettes, proposed by the U.S. Food and Drug Administration, will lead more than 1.3 million smokers to quit. Among them, Black smokers will see the greatest impact.

Pediatric transplant patients may skip adult appointmentsYoung adults who received organ transplants as childrenmay not be regularly attending their doctor appointments after leaving their pediatric providers.

Large-Scale Social Media Analysis Reveals Emotions Associated with Nonmedical Prescription Drug UseThe behaviors and emotions associated with and reasons for nonmedical prescription drug use (NMPDU) are not well-captured through traditional instruments such as surveys and insurance claims.

New insight in patient response to surgical disruption in life-saving hormonesCardiac surgery patients may experience different levels of disruption to their body producing life-saving hormones during their operations, a new study reveals.

Radiologists, AI Systems Show Differences in Breast-Cancer Screenings, New Case Study FindsRadiologists and artificial intelligence systems yield significant differences in breast-cancer screenings, revealing the potential value of using both human and AI methods in making medical diagnoses.

Montefiore Einstein Cancer Center Finds CAR-T Therapy Effective in Black and Hispanic PatientsCAR-T therapy, a form of immunotherapy that revs up T-cells to recognize and destroy cancer cells, has revolutionized the treatment of blood cancers, including certain leukemias, lymphomas, and most recently, multiple myeloma.

Tackling the Consequences of Long CovidA research team at the University of Zurich has helped people affected by Long Covid identify the problems they most urgently want scientists to tackle, through a collaborative citizen science approach.

Self-sampling for cervical screening offered at the point of invitation: A cross-sectional study of preferences in EnglandThis study assessed preferences for human papillomavirus (HPV) self-sampling if offered as an alternative to clinician-based screening at the point of invitation for cervical screening.

New study identifies genetic changes in patients who progress to esophageal cancerLed by researchers at Fred Hutchinson Cancer Research Center, a scientific team that studies a precancerous condition of the esophagus (called Barretts esophagus or BE) are working to answer this question.

Risk Factors for Severe COVID-19 in Hospitalized Adults Differ by AgeA just-published study provides previously unknown answers about which hospitalized COVID-19 patients are most likely to need mechanical ventilation or to die.

Hypoxia-activated neuropeptide Y/Y5 receptor/RhoA pathway triggers chromosomal instability and bone metastasis in Ewing sarcomaAdverse prognosis in Ewing sarcoma (ES) is associated with the presence of metastases, particularly in bone, tumor hypoxia and chromosomal instability (CIN).

Unravelling the origins of the human spineEMBL Barcelona scientists have recapitulated for the first time in the laboratory how the cellular structures that give rise to our spinal column form sequentially.

New Study Finds Climate Change Could Spark the Next PandemicAs the Earths climate continues to warm, researchers predict wild animals will be forced to relocate their habitats likely to regions with large human populations dramatically increasing the risk of a viral jump to humans that could lead to the next pandemic.

How brains form visual mapsMaps have played an important role in scientific progress. Claudius Ptolemaeus transformed our understanding of the world with his map of Earth and Tycho Brahe our understanding of the Universe with his map of the stars.

Efficient dendritic learning as an alternative to synaptic plasticity hypothesisSynaptic plasticity is a long-lasting core hypothesis of brain learning that suggests local adaptation between two connecting neurons and forms the foundation of machine learning.

More Relaxation and Less Stress Through Combined Yoga TechniquesYoga is often equated with acrobatic stretching exercises that are supposed to induce relaxation and a better body awareness.

Carrier for Chemotherapy Medications CreatedA group of scientists at Ural Federal University has proposed the use of polyoxometallate nanoclusters as a carrier for chemotherapy medication.

Free Fundamental Biology of Endocrine, Metabolic & Resistant conditionsThereference Free Radical Biology of Endocrine, Metabolic & Immune disorders uniquely explores the science of signalling mechanisms associated with diseases like endocrine, metabolic, and immune disorders which are linked to oxidative stress-mediated disease mechanisms.

All Cells Are Important: A Roadmap to Characterize Lymphoma StromaLymphomas are blood cancers that often start from lymph nodes. Lymph nodes contain not only hematopoietic cells, mainly B- and T-lymphoid cells, but also non-hematopoietic cells (NHCs), also called stromal cells.

Machine learning can help address stigma of substance abuse in developing countriesNow, a research team is using machine learning and anonymized data to get a clearer picture of the underlying factors that influence tendencies to abuse drugs and alcohol.

Gene mutations that contribute to head and neck cancer also provide precision treatment targetsAbout one-fifth of often deadly head and neck cancers harbor genetic mutations in a pathway that is key to normal cell growth, and scientists report those mutations, which enable abnormal cancer cell growth, can also make the cancer vulnerable.

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StudyFinds Blotter: Other Notable Health Research From April 28, 2022 - Study Finds