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Psychological Stress Distracts the Immune System from Fighting Infections – The Scientist

Posted: August 14, 2022 at 2:33 am

Psychological stress can have a direct effect on bodily functions such as the immune system.

By affecting white blood cell populations, acute and chronic psychological stress can decrease a bodys ability to fight off infection, but how the brain communicates with the immune system to do this is unclear. Filip Swirski, a professor at the Icahn School of Medicine at Mount Sinai, New York, explores this form of inter-organ communication. A big question is how do the various organs in our systems respond to external factors and lifestyle changes, whether that's sleep, diet, exercise, or stress, because our body systems really adapt to fluctuations in our environment, said Swirski.

In a recent study published in Nature,Swirski and his group showed that inducing acute stress in mice caused profound changes in the immune system.1 Specifically, B and T cells left the lymph nodes and rapidly migrated to the bone marrow. We were both very surprised to see how massive these immune shifts are within very short periods of stress, said Wolfram Poller, a clinician-researcher and first author of the study. As a consequence, these stress-induced immune system shifts had a profound effect on disease susceptibility, decreasing a mouses ability to tolerate influenza or SARS-CoV-2 infections.

Next, Swirskis team wanted to identify the specific brain networks that caused this physical change in the immune system. The researchers first explored the paraventricular hypothalamus (PVH), a region controlled by the sympathetic nervous system (SNS) that is important in stress and the fight or flight response. By activating or inactivating specific neurons in the PVH, the researchers found that they could induce or reduce leukocyte migration to the bone marrow. Because lymphatic tissues play a major role in immune tolerance, they modeled autoimmune disease in mice and found that when stressed, these mice displayed fewer detrimental outcomes, such as inflammation and paralysis, due to the immune cell migration away from the lymph nodes. These experiments revealed an important aspect of how psychological stress can dampen the responses leading to autoimmune disorders while also decreasing the bodys ability to withstand infectious disease.

We were both very surprised to see how massive these immune shifts are within very short periods of stress. Wolfram Poller, Icahn School of Medicine at Mount Sinai, New York

Swirskis team also found that in response to acute stress, neutrophils became more prevalent in multiple tissues. Neutrophils aid in the repair of tissue damage; therefore, their distribution to multiple areas in the body prepares it for possible injury. The scientists again looked at the SNS for answers and were surprised to find that it was not involved in the neutrophil response. Instead, they looked for neutrophil modulators in the blood and identified CXCL1, a protein in muscle that changed in response to stress. By inactivating or stimulating the specific motor circuit neurons in the brain known to control muscle movements, the researchers modulated the neutrophil response, making this study one of the first to find a direct mechanistic connection between a specific brain region and its effect on the immune system.

What this paper does is it [goes] into the detailed brain pathways that are important in regulating different parts of the immune response, said Esther Sternberg, the research director for the Andrew Weil Center for Integrative Medicine at the University of Arizona at Tucson, who was not involved in the study. How elegant and miraculous is it that when youre so stressed that you need to fight or fleeyou could be injuredthe immune system sends the neutrophils to exactly where they need to be.

While stress prepares the body for injury, it also makes the body more susceptible to infectious disease by dampening other immune responses. Swirski and his group are now interested in the questions these findings raise about how people with socio-economic struggles deal with chronic or acute stressors and whether their bodies are prepared to deal with viral infections. That relationship is something that I think is worth exploring, to inspect how some of these socio-economic factors really put our immune systems at a disadvantage, said Swirski.

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OSSIO Announces U.S. Launch and First Commercial Use of OSSIOfiber Suture Anchors, Expanding Patient Access to Growing Portfolio of Bio-Integrative…

Posted: August 14, 2022 at 2:33 am

WOBURN, Mass.--(BUSINESS WIRE)--OSSIO, Inc., a fast-growing orthopedic fixation technology company, announced today the U.S. launch and first commercial use of OSSIOfiber Suture Anchors, expanding patient access to the companys growing portfolio of bio-integrative implants for use in foot/ankle, shoulder, knee, hand/wrist and elbow surgery.

Gregory Berlet, M.D., founding partner at Orthopedic Foot and Ankle Center in Columbus, Ohio, recently became the first surgeon to use the new implant in clinical practice.

The new OSSIOfiber Suture Anchors provide amazing strength and biology that I trust to be predictable and safe for my patients, Dr. Berlet, chief medical officer of OSSIO, said. Utilizing OSSIOs trusted bio-integrative material, these anchors allow me to maintain my preferred technique for soft tissue fixation procedures while improving my results. This is another big step for OSSIOfiber in becoming a new material standard in orthopedic fixation.

OSSIOfiber Suture Anchors were FDA cleared in March 2022 for use in fixation of suture (soft tissue) to bone in the shoulder, foot/ankle, knee, hand/wrist, and elbow in a variety of specific orthopedic procedures. These implants were designed to achieve unrivaled strength and unmatched safety using their proprietary OSSIOfiber Intelligent Bone Regeneration Technology that leaves nothing permanent behind.

Additionally, the anchors proprietary DURAlinkTM Coupling Technology acts to increase stability and prevent suture slippage by connecting the eyelet to the anchor, creating a single stable unit. OSSIO will initially launch the 4.75mm system into the foot and ankle market, followed by the companys first entry into the sports/shoulder markets later this year.

The OSSIOfiber 4.75 Suture Anchor represents a substantive breakthrough in soft-tissue-to-bone fixation, said Frank Petrigliano, M.D., chief of the University of Southern California Epstein Family Center for Sports Medicine in Los Angeles. The implants can be utilized for a broad array of sports medicine procedures, and demonstrate strong, predictable bio-integration. This technology provides a biocompatible option that achieves excellent fixation without concern for implant fracture or incomplete integration into host bone. I look forward to using the OSSIOfiber 4.75 suture anchor for my sports and shoulder cases.

OSSIO CEO Brian Verrier added: Expanding our commercialized portfolio of OSSIOfiber implants, as well as patient access to additional bio-integrative solutions, is mission critical for the companys continued success, and the launch of our suture anchors mark a significant milestone in that effort. Sports and extremity surgeons have been asking for non-permanent suture anchors that deliver improved strength and pull-out resistance, while providing safe, predictable bio-integration. OSSIOfiber Suture Anchors have shown strength that is unrivaled and safety that is unmatched in the market, as demonstrated by our bench testing and 30 month in-life studies compared to currently marketed bio-composite anchor controls.

Additionally, Verrier said, our products offer enhanced ease of use due to the incredible insertion strength of our continuous mineral fiber-based platform. We are excited to offer our customers a suture anchor that provides confidence during the healing process while avoiding many of the late issues sometimes seen in traditional suture anchors.

About OSSIOfiber Intelligent Bone Regeneration Technology

All OSSIO implants are made with OSSIOfiber Intelligent Bone Regeneration Technology, a breakthrough in fixation material that provides the first credible solution to the shortcomings of permanent metal hardware, conventional resorbable and allograft implants, combining unparalleled mechanical strength and natural bone healing in a non-permanent implant. Made from a proprietary mineral fiber matrix held together by a naturally degradable polymer, its bio-integrative material properties provide surgeons with a more biologically friendly way to restore patient stability and mobility while leaving nothing permanent behind.

Designed for rapid bone in-growth, regeneration and replacement, OSSIOfiber Intelligent Bone Regeneration Technology is a first-of-its-kind implant material stronger than cortical bone. OSSIOfiber is engineered to provide the strength required for functional fixation and allows for full integration into the native anatomy without adverse biological response. OSSIOfiber implants utilize existing reimbursement and surgical techniques.

OSSIOfiber Intelligent Bone Regeneration Technology can address many surgical applications through the manufacturing of endless implant designs, including nails, screws, staples, anchors and plates. The company intends to pursue multiple applications in the distal extremity, trauma, sports, reconstruction, pediatrics and spine segments. For more information on OSSIOfiber implants, please visit http://www.ossio.io.

About OSSIO

OSSIO is an orthopedic fixation company committed to transforming the orthopedic experience for patients, physicians and payors. Founded in 2014, its vision is to provide the first credible replacement to metal implants in the multibillion-dollar global orthopedic fixation market with its OSSIOfiber Intelligent Bone Regeneration Technology. OSSIOs development headquarters is located in Caesarea, Israel, and its commercial headquarters is in Woburn, Mass. (USA). For more information on the company, visit http://www.ossio.io.

Forward-looking statements contained herein are based on estimates and assumptions of OSSIO management and are believed to be reasonable, though they are inherently uncertain and difficult to predict.

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The CEOs Disrupting and Democratizing Women’s Health – Marie Claire

Posted: August 14, 2022 at 2:32 am

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At a time when our bodily autonomy is under attack, women have become more vigilant about their basic human rights to equality, information, and the highest attainable standard of healthincluding sexual and reproductive health without discrimination. But the traditional healthcare system tends to treat the complex needs of women all wrong. It takes an acute approach rather than preventative. Disparate versus integrative. As a result, American women are suffering through a national infertility crisis and high maternal mortality (a rate of 23.8 to be exact, the worst among industrialized nations). The Covid-19 pandemic meanwhile has had lasting effects on the state of mental health for women, who are already twice as likely to experience depression and anxiety than men.

In an effort to change this, numerous founders are disrupting the wellness industry as we know it. We spoke with three who were unwilling to wait for the massive ship that is the American healthcare system to course correctone a former investment banker, another a former journalist, and the third a doctor-turned-serial entrepreneur. They recognize that, for women, innovation is a matter of life and death.

Kimberly Seals Allers, founder of Irth

(Image credit: Future)

With her first pregnancy, Kimberly Seals Allers, a former reporter at Fortune and editor at Essence, deployed her journalistic skills to research the best hospitals. But when she gave birth, her experience didnt match the glowing reviews.

I walked [into] a highly rated and best of hospital in New York City, having done months of due diligence and reading reviews, says Allers. But I left feeling disrespected, traumatized, and unseen.

This impacted her earliest memories of motherhood. I blamed myself completely, unaware that people are not being treated the same way even in the same place.

According to a White House statement issued on its first Maternal Health Day of Action in 2021, the U.S. has the highest maternal mortality rate of any wealthy nation. For women of color, the reality is stark. According to the CDC, Black, American Indian, and Alaska Native women are two to three times more likely to die from pregnancy-related complications than white women. The pregnancy-related mortality rate for Black women with at least a college degree was 5.2 times that of their white counterparts.

So in February 2021, Allers launched Irth, an app that seeks to equalize the experience of delivering a child by giving women a central platform for rating and reviewing hospitals, OB-GYNs, and other pre- and post-natal care providers. Think of it like Yelp, but for childbirth, aimed at helping Black and Brown women access the best prenatal, birthing, postpartum, and pediatric services.

It started as a mommy-son project. Her youngest child, Michael, then a 13-year-old coding enthusiast, created the apps wireframes and soon, the duo started going to pitch competitions. I had this idea for an app and thought this would be a great way to bridge our worlds, says Allers. In 2018, they went to an MIT hackathon related to birth and breastfeeding and won the Media for Change award. There, they met an MIT engineer who went on to build Irths prototype, which enabled Allers to get more grant funding. To date, Allers has raised more than $850,000 in grants. I'm really proud of our origin story, she says.

Were turning our anonymized reviews into qualitative data...to give every Black birthing person a five-star experience while bringing life into the worldwhich is what we all deserve.

Earlier this year, she was invited to meet with Tim Cook during Apples Worldwide Developers Conference, where Apple recognizes trailblazing creators uplifting their communities through technology. Apple also featured Irth in a spotlight (opens in new tab) on the App Store to grow awareness. It was an incredible platform to share about Irth and our mission to remove the bias from birth, says Allers.

To date, Irth has more than 20,000 users and reviews from 48 states. Allers is most alarmed by the frequency at which women of color are going through similarly poor experiences, such as hearing negative comments from care providers about family size or marital status. There were too many reviews from fathers saying they were referred to as Mr. Baby Daddy while supporting their partner; Black women being coerced and admonished about birth control while in active labor, says Allers.

Right now, according to Allers, the number-one negative experience being reported on the Irth app nationwide is: "My requests for help were ignored or refused."Such medical racism has resulted in disrespect and death. A common thread in every maternal death story is that too many hospitals want to dismiss or explain away these reports of pain, instead of taking them seriously.

Irth has its sights on reform. The team of just 15 employees recently launched pilot programs with five hospitals to improve patient care for Black mothers. Allers says the hardest work is being done at the community level, encouraging more women of color to submit reviews. After all, it will take sheer volume to sound the alarm bells on one of the biggest failures of the countrys healthcare system.

Were turning our anonymized reviews into qualitative data to teach providers, payers, and hospitals how to give every Black birthing person a five-star experience while bringing life into the worldwhich is what we all deserve.

Rebecca Parekh, ceo and cofounder of The Well.

(Image credit: Future)

Step into The Well's New York City flagship, and one might wonder whether theyve entered a luxurious retreat in Montauk or Malibu. But smack in the middle of Manhattan, visitors to The Well can book meditation classes in a glowing white dome, access body treatments rooted in Traditional Chinese Medicine and Ayurveda, or try their hand at hydrotherapy, aromatherapy, meditation, and more.

Rebecca Parekh, cofounder and CEO, says the very premise of her business is to integrate holistic health into the urbanite's day-to-dayand that meant building a geographically accessible hub to promote such a lifestyle.

Our original business was a physical business and were remaining true to that because were passionate about the in-person experience and offering integrated wellness in big, busy cities, she says. Its not a common mindset in this Web3, Metaverse-obsessed startup world.

Burnout in her previous career led Parekh to rediscover the importance of holistic health. "I was an investment banker and was not modeling a wellness lifestyle; when it comes to getting swept into hustle-culture, I got disconnected," says Parekh, who worked at Deutsche Bank for 10 years. Her mom encouraged her to simply cook more and practice yoga daily. Parekh ultimately left banking, transitioning to work as Executive Director of the Global Foundation for Eating Disorders, and then COO for Deepak Chopra Radical Wellbeing.

She began envisioning a business that would promote health on a grander scale and on a daily basis. In 2016 she teamed up with cofounders Sarrah Hallock and Kane Sarhan to begin fundraising for The Well. It opened its nearly 15,000-square-foot Manhattan flagship, complete with a full-service restaurant and retail shop in September 2019just six months before the pandemic made in-person experiences practically obsolete.

Parekh and cofounders began offering digital wellness classes and services, such as a three-part webinar focused on how to ease the anxiety of returning to office work and the outside world after months in lockdown. It also focused on e-commerce for its line of vitamins, supplements, and personal care goods.

Although The Well nimbly pivoted to digital during the pandemic, its cofounders never abandoned their commitment to physical locations and products. Through a partnership with Auberge Resorts Collection, the company continued to invest in its second location at The Mayflower Inn & Spa in Connecticut, which opened in November 2020, then its third spot, Hacienda AltaGracia, in Costa Rica in 2021.

To date, The Well employs about 100 people and has raised roughly $50 million in venture capital. After surviving Covid-19 closures, the brand is set for expansion: Parekh says The Well will likely open two more locations by the end of the year, and confirmed the company is working on projects in Mexico, Miami, London, and Aspen.

While it grows via brick-and-mortar, the company is staying grounded in an industry driven by fads. Parekh credits The Wells medical and nutrition teams with vetting everything, from services offered to ingredients served in the restaurant. The rigorous standards are set forth by Frank Lipman, M.D., Chief Medical Officer and a renowned voice in integrative and functional medicine. He went from quack to guru, as [mainstream] folks are now believing in what hes been talking about for quite some time, says Parekh.

And in an industrywellnessthat can mean many things and nothing at once, The Well filters out fads by making sure each service fits within the brands key pillars: nutrition, body work, skincare, lifestyle, community, and, a newly added category: emotional wellbeing.

We focus on meeting people where they are at in their wellness journeys, says Parekh. Whether youre sick or not we believe yoga is medicine, along with the food we eat.

Parsley Health founder and CEO, Dr. Robin Berzin.

(Image credit: Future)

Just 13 percent of healthcare CEOs are femaleand even fewer are M.D.s. But Dr. Robin Berzin has defied these odds. In 2011, the graduate of Columbia Universitys College of Physicians and Surgeons cofounded Cureatr, an app that streamlines communication with physicians. That experience with health-tech inspired her to launch Parsley Health in 2016this time as a solo female founder.

Parsley Health is a functional medicine company that takes a preventive approach to chronic disease management. It uses a holistic snapshot of a patients sleep, fitness, nutrition, family history, and mental health to determine the best regimens and health protocols.

When we look at the body as an integrated systemrather than isolated partswere able to implement the right solution at the right time.

It has served tens of thousands of patients nationwide via telehealth, in addition to in-person clinics in New York City and Los Angeles. We have independent data showing that Parsley's approach to care improves health while reducing specialist referrals and prescription drug use, Dr. Berzin says. According to company data, by year two, patients have reduced their referrals to specialists by 77 percent. Those previously on chronic medications see a 65 percent reduction in prescription drug use.

We closely monitor their health to ensure that their concerns were heard, their treatments were working, and, ultimately, that we were measurably putting them on a path to feeling better, says Dr. Berzin. She points to the initial visitwhich takes 75 minutes, five times longer than the average appointment with a primary care physicianas the real changemaker.

Last year was a big one for Dr. Berzin. In response to the wellness wave sparked by Covid-19, she grew telehealth from seven states in 2020 to a nationwide operation in early 2021. She also raised a Series C round of venture capital, bringing the total raised to date to more than $100 million. She finished writing her first book, State Change (opens in new tab).

Last but not least, she welcomed her third child. In August 2021, she posted a beaming Instagram photo of herself just three weeks before giving birth, and wrote I convinced myself at 39 that I was too old to get pregnant easily, even though of course I know better. I help women beat the fertility odds every freaking day at work!

With a female physician and a mother of three at the helm, Parsley Health is a family practice with an emphasis on transforming womens healthcare. Its programs are designed to support women throughout their reproductive lifecycle: pre-conception, fertility, pregnancy, and postpartum. Last month, the company announced the launch of comprehensive menopause care.

Menopause affects more than 55 million American women and yet 73 percent of these women will suffer in silence without treatment. Perimenopause symptoms can start as early as age 45 while menopause can last for a decade. And, too often, according to Darcy McConnell, M.D., Director of Medical Affairs at Parsley Health, older women experience age-related conditions that are misattributed to menopause. For example, bloating and weight gain are often blamed on hormones, but can actually be due to high cortisol levels, leading to incorrect treatments.

Parsley Healths menopause protocol will deviate from the traditional practice of defaulting to hormone replacement therapy (HRT), which, according to Cancer.gov, is linked to numerous side effects including vaginal bleeding, dementia, and breast cancer. Parsley Healths holistic model instead takes a closer look at a womans metabolic health and mental health to offer a comprehensive system for monitoring multiple causes and conditions.

Dr. Berzin says Parsley Health aims to connect the dots, which traditional, patriarchal medicine has failed to do: When we look at the body as an integrated systemrather than isolated partswere able to implement the right solution at the right time, which halts the cycle of frustration women experience when theyre stuck in the revolving door of specialist referrals and prescription drugs.

(Image credit: Kanya Iwana / Brittany Holloway-Brown)

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On the way to quantum sensors – EurekAlert

Posted: August 14, 2022 at 2:32 am

image:Schematic of a quantum sensor in which a biomolecule (pink) is anchored to a surface of hexagonal boron nitride on which the spin defect (red) is located. The latter operates as a sensitive probe for the environment. view more

Credit: Andreas Gottscholl / University of Wuerzburg

The new research project IQ-Sense - Integrated Spin Systems for Quantum Sensors aims to measure physical quantities such as temperature, pressure, magnetic or electric fields with unprecedented precision. Such measurements using quantum sensors are of fundamental importance in the natural and engineering sciences, but also in the life sciences and medicine.

The project brings together research groups from Julius-Maximilians-Universitt Wrzburg (JMU) and Technische Universitt Mnchen (TUM), both in Bavaria, Germany. The complementary expertise represented in the project includes physics, chemistry, life sciences and medicine.

On the one hand, the synergistically linked groups from the two universities aim to explore the fundamentals of advanced quantum sensor technology using several identified solid-state platforms. On the other hand, they are going to develop and demonstrate integrated quantum sensors for spectroscopic and imaging applications in biomolecular and biomedical settings.

The project is coordinated by the Wrzburg Professor Vladimir Dyakonov, head of the JMU Chair of Experimental Physics 6. Other JMU participants come from the Institute of Physics, the Biocentre and the Rudolf Virchow Centre for Integrative and Translational Imaging.

Free State promotes lighthouse projects

The Bavarian State Ministry of Science and the Arts is funding IQ-Sense as part of the initiative "Lighthouse Projects for Research, Development and Applications in Quantum Sciences and Quantum Technologies". Around three million euros have been approved for the project over three years. Half of the sum will go to Wrzburg.

Minister of Science Markus Blume: "We want to specifically support interdisciplinary and cross-university projects that can lay the foundations for groundbreaking innovations. Innovations that we can't even imagine exist today."

New quantum professorship for Wrzburg

As part of this Bavarian funding initiative, JMU will also receive a new quantum professorship for Computational Quantum Materials. The Ministry already announced this in June 2022; the appointment procedure for the professorship is underway. The new professorship was applied for by JMU physics professors Bjrn Trauzettel and Ralph Claessen.

The Free State is funding the establishment of the new professorship at JMU with around 1.5 million euros over five years.

Both successful applications will strengthen the Wrzburg-Dresden Cluster of Excellence "ct.qmat - Complexity and Topology in Quantum Matter".

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.

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New Five Points Venue Will Showcase Denver Music, Art, Food and Wellness – Westword

Posted: August 14, 2022 at 2:32 am

Three longtime local creatives are coming together to make some magic in the Mile High City. And if Iman Haidar, Crystal Wiggins and Corey Jacobs hit their mark, Society Denvercould be one of Denver's best venues when it opens early next year at 3090 Downing Street, a big building on the edge of Five Points that got its start as a church. The lineup of offerings they propose for the place is enticing and seemingly endless, including live music from local, national and international acts; yoga and meditation classes; body work; workshops; galleries for artists; healthy, soulful food; and even an apothecary and elixir bar.

Our goal with Society is to set a precedent of what is possible in a community space in Denver, says Haidar. We are driven to offer more than just a physical space, but to fill it with purpose and inspiration for our community to flourish in. Keeping the synergy of the mind, body and soul as a guiding principle, we are committed to creating an inclusive space that fosters creativity, celebration and connection."

Denver Society has been a long time coming, though.

"The concept came around for me personally around May of 2019," Haidar recalls. "I realized having the intersection of art and music and wellness and healthy food and community is what really has helped me thrive, and I thought it'd be really cool to have a space that has all of it under one roof."

A rendering of the Alive space.

Society Denver

But not without its challenges. The trio found the building almost three years ago; it had been vacant since the Wrangler moved out in 2018.Before it became a bear bar, it was a members-only swingers' club, and before that, a slew of restaurants, from the Kiva all the way back to the Hacienda, which the MacIntosh family opened after converting the former church into an eatery.

"The building is now owned by GHC Housing Partners, which is normally involved with developing affordable housing. Weve been working directly with Alex Berbit, and a commercial space like this took some creativity and patience," says Haidar. "They didnt want to just sign a lease with any business they could; they wanted a business that aligned with their values. Overall, they have showed up with such support for our success and truly believe in our concept and the value that we will be giving back to the neighborhood and community. Theyve been amazing to work with, and we feel really grateful to be in their building.

"The pandemic hit right before we signed the lease," she recalls. "So we kind of had some ups and downs with that, but ultimately, that place has always felt like where it's meant to be. It just fits so well. It flows so well. It has sectioned-off areas, but they all feel so symbiotic with each other. And now when I walk in, I can't imagine it being anywhere else."

The founders' ideas are backed up by years of experience. Jacobs opened Thrive in Boulder in 2015, and the popular vegan eatery was named a top ten Colorado restaurant by National Elite in 2018. He also has an audio engineering degree and is a reiki master and massage therapist. Wiggins had a background in music festival production, artist management and as an agent when she moved to Denver twelve years ago; she established herself here working with Beatport, Sonic Bloom, Sub.mission, Cervantes', UMS and Yeah Baby, a disco pop-up in RiNo."I have been a talent buyer at multiple different events and festivals globally and in Colorado," Wiggins says. "I'm really looking forward to implementing the skills that I have."

Haidar also has a music background, having worked at Black Box and large-scale festivals from Tomorrowland to Burning Man. "I came out here around 2014 for school. I double-majored in biochemistry and integrative medicine, so I come from a strong science background. And then after that, I also went to the Colorado School of Clinical Herbalism and completed the medical herbalism program, so I'm definitely gonna be infusing that into a lot of the stuff and [wellness space] Alive and the apothecary," she explains. "I'm also an avid yogi, and I help to co-run a performance company and an event company called Pyroglyphics. We do all kinds of performance art, such as fire dancing, aerial arts, belly dance, burlesque, contortion, all kinds of circus stuff. We perform internationally, and that's still running right now."

A rendering of Thrive.

Society Denver

Each floor will showcase a different aspect of the creative hub. Society Denver's first floor will be a second location of Thrive; the space will be filled with greenery and have enough room to allow for performances at dinner. "We'll have Iman coordinating aerials and different types of shows like belly dancing, and we'll have music theater events and different dinner and theater experiences...for a full sensory experience," Wiggins says.

Performance art will also happen on the next floor, labeled Vibe. This will be Wiggins's arena, a sprawling space with VIP booths and a capacity of 600. "No one wants to be shoulder to shoulder at a concert," Wiggins says. Those concerts will include all genres of music."We want to have local artists, we want to support the community," she adds. "We're so tied in with so many different communities with the music as it is, too, that we already have a ton of people ready to support us that are on an international, massive level."

During the day, the first floor will house pop-up galleries and be used as a general gathering and workspace, as well.

The third floor, Alive, will showcase Haidar's expertise. The wellness space will host many holistic offerings, such as energy and body work, sound baths, masseuses, yoga and more.

The building will also house a major mural project headed by Allie Grimm, aka A.L. Grime, named the Best Influential Muralist in the Best of Denver 2022. The project will involve twenty artists, who will paint both the interior and exterior of the space. Grimm's mural will be outside Alive, and will be created during the mural festival she is coordinating, Denver Walls.

"Allie's a longtime friend of mine," Haidar says. "She's also just an inspiring, badass woman powerhouse in her industry. We've worked together for years, and she's already curated a bunch of the murals that are up at the building."

A rendering of Vibe's daytime look.

Society Denver

But first, the partners need to finish and staff the space. They are hiring for more than sixty positions and have created an IndieGoGo to reach a $50,000 goal, which will be used for purchasing more equipment, furnishing, employee training and renovations. Donors will receive perks ranging from yoga classes to food and membership deals.

"Society Denver is open to everybody. You don't need to be a member to access any aspect of it at any point in the day except for some select private events," Wiggins notes.

"We're very connected in the art world," she continues. "We have a friend who's going to be making us a custom chandelier. He's a glassblower here. There are so many cool little things like that, but we're just so excited to bring attention to these people at Society Denver. They deserve it."

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Adtalem Global Education Medical Schools Partner with Southern California University to Expand Pipeline of Physicians – Business Wire

Posted: August 14, 2022 at 2:32 am

CHICAGO--(BUSINESS WIRE)--Adtalem Global Education (NYSE: ATGE), a leading educator and provider of professional talent to the healthcare industry, has established a partnership between its two medical schools, American University of the Caribbean School of Medicine (AUC) and Ross University School of Medicine (RUSM), and Southern California University of Health Services (SCU) to expand access to education for aspiring physicians looking to earn a Doctor of Medicine (MD) degree. Through this partnership, SCU students who graduate from the Master of Science in Medical Science (MSMS) program and get accepted to either AUC or RUSM, can receive up to $10,000 in scholarships or additional funding. The three-year agreement began in July 2022.

Adtalem and its leading medical institutions, AUC and RUSM, are committed to expanding access to education and supporting students to pursue medical education, said John Danaher, M.D., president of Adtalem Medical and Veterinary. This partnership will provide needed funding to a diverse group of students who have the talent but may not have access or opportunity to pursue their education and career path in the health sciences.

SCUs post-baccalaureate MSMS degree can be completed in as little as one year and seeks to strengthen students academic skills and credentials for entry into medical, dental, physician assistant, veterinarian, or other professional health care programs.

"This new agreement is excellent news for SCU MSMS students with dreams of becoming medical doctors, said Raheleh Khorsan, Ph.D., program director, MSMS Program at SCU. SCU is proud to have been educating medical science students since our MSMS Program began in 2020. This agreement creates the opportunity to increase the number of both medical sciences students, and future medical students at AUC and RUSM. It is through institutional agreements such as this that our common goal can be reachedto increase health sciences and medical students to fill the need for additional healthcare professionals for communities."

AUC and RUSM are part of the Adtalem family of institutions dedicated to healthcare workforce solutions and actively partner with mission-driven organizations to reduce educational barriers and empower career development. AUC and RUSM are committed to superior student outcomes and achieved strong residency placements with a combined 95% first-time eligible residency attainment rate for 2021-22 graduates and expected graduates (as of April 5, 2022).

To learn more about the agreement, please visit: https://www.scuhs.edu/wp-content/uploads/RUSM-and-AUC-Interview-and-Scholarship-Details.pdf.

About Adtalem Global

Adtalem Global Education (NYSE: ATGE) is a leading healthcare educator and provider of professional talent to the healthcare industry. With a dedicated focus on driving strong outcomes that increase workforce preparedness, Adtalem empowers a diverse learner population to achieve their goals and make inspiring contributions to their communities. Adtalem is the parent organization of American University of the Caribbean School of Medicine, Chamberlain University, Ross University School of Medicine, Ross University School of Veterinary Medicine and Walden University. Adtalem and its institutions have more than 10,000 employees and a network of more than 275,000 alumni. Adtalem was named one of Americas Most Responsible Companies 2021 by Newsweek, and one of Americas Best Employers for Diversity in 2021 and 2022 by Forbes. Follow Adtalem on Twitter @adtalemglobal, LinkedIn or visit Adtalem.com for more information.

About American University of the Caribbean School of Medicine

American University of the Caribbean School of Medicine (AUC) is an institution of Adtalem Global Education, a global education provider headquartered in the United States. Founded in 1978, AUC School of Medicine has more than 7,000 alumni, many of whom work in primary care or underserved areas. With a campus in Sint Maarten, affiliated teaching hospitals in the United States and the United Kingdom, and internationally recognized faculty, AUC School of Medicine has a diverse medical education program for todays globally minded physician. For more information visit aucmed.edu, follow AUC School of Medicine on Twitter (@aucmed), Instagram (@aucmed_edu) and Facebook (@aucmed).

About Ross University School of Medicine

Ross University School of Medicine (RUSM) is an institution of Adtalem Global Education, a global education provider headquartered in the United States. Founded in 1978 and located in Barbados, RUSM has more than 14,000 alumni and is committed to educating a diverse group of skilled physicians. RUSM is accredited by the Caribbean Accreditation Authority for Education in Medicine and Other Health Professions (CAAM-HP). For more information, please visit medical.rossu.edu and follow RUSM on Twitter (@RossMedSchool), Instagram (@rossmedschool) and Facebook (@RossMedSchool).

About Southern California University of Health Sciences (SCU)

Over a century after Los Angeles College of Chiropractic (LACC), Californias first chiropractic school was established in 1911, it grew into Southern California University of Health Sciences (SCU), an expanded, multi-program university that is transforming and redefining health and healthcare education. SCU is committed to providing an academic community imbued with kindness, integrity, humor, and determination; and a culture of diversity and inclusion. SCU specializes in integrative whole-person healthcare education that goes beyond the diagnosis - and that treats the whole person. Since 1911, SCU has trained more than 18,000 future healthcare providers. For more information, visit scuhs.edu/.

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Adtalem Global Education Medical Schools Partner with Southern California University to Expand Pipeline of Physicians - Business Wire

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Advanced Methods in Alternative Cancer Treatment – The Epoch Times

Posted: August 14, 2022 at 2:32 am

Suppose youve received the dreaded diagnosis and youre evaluating your options for treatment. While friends and family may be urging you to go the conventional route, you believe there must be a better, less toxic way than destroy to heal. Heres a glimpse into that other, often hidden world.

Dr. Nathan Goodyear started out as a gynecologist and pelvic floor surgeon. Once out of residency, however, he noticed that a lot of what he had been taught in medical school didnt work. Then, in 2006, he developed pheochromocytoma, a rare type of tumor that develops in the adrenal gland, causing it to excrete high amounts of norepinephrine, which, in turn, causes extremely high blood pressure and heart rate.

That experience pushed him to make the transition into the field of cancer research. For the past 5 1/2 years, hes been working with Brio-Medical, a holistic cancer clinic in Scottsdale, Arizona, and for the past six months, he has served as its medical director. He works with four other physicianstwo medical doctors and two naturopathic physicians.

Goodyear is a firm believer in the benefits of vitamin C in cancer treatment. Coincidentally, were both scheduled speakers at the Vitamin C International Consortium Institutes annual conference in Tampa, Florida, on Sept. 9 and 10.

He says the current approach to cancer has some significant limitations. Places like Brio-Medical are working to find better approaches.

The conventional approach seems to follow the logic destroy to heal, and I just dont know where that really occurs in nature outside conventional cancer treatment. Healing has to be your focus and goal to achieve healing. You have to heal to heal. Our healing strategy focus in cancer is to tap into the bodys designed capacity to heal itself through the targeting of the root causes, Goodyear said.

When you look at holistic natural therapies, theres this assumption by many, including conventional medicine, that we are just throwing darts up on the wall and hope they stick.

But in actuality, were following the science of genomics, epigenomics, transcriptomics, metabolomics, and immunomodulomics. This is the future of medicine thats here now, and were being incredibly specific and targeted for the dysfunction within the cancer, but with natural holistic or integrated therapy.

Examples of holistic therapies used for cancer include vitamin C in combination with artemisinin or artesunate (a primary malaria medication). This combo is very good for prostate and breast cancer in particular. Curcumin and melatonin both also have significant anticancer effects. Goodyear likes to combine hyperthermia with high-dose vitamin C and curcumin.

Studies have shown that when you give vitamin C with whole-body hyperthermia, you actually achieve a higher plasma ascorbic acid concentration. So thats going to impact the fight against cancer more, he said.

Mistletoe is another excellent cancer treatment.

One key point to be made about holistic oncology is that the earlier you start this kind of treatment, the better. Unfortunately, most patients who seek alternative strategies have already done tremendous damage to their bodies, particularly the immune system, with one, two, or even three rounds of chemo, which really impairs your bodys ability to heal naturally.

If we can get them earlier in the process before they get conventional chemo and/or radiation, the impact is huge, Goodyear said.

Before you destroy the immune system, one can actually heal with the immune system. I cant tell you how many ladies with breast cancer have been able to preserve their breasts with this cancer healing strategy. You can actually heal the body, not destroy it. That is a novel concept because when you destroy the immune system through conventional therapy, youre going to see cancer recur and spread.

Typically, its not the initial cancer that kills you. What kills is when the cancer spreads (metastasizes) to other areas of your body. This kind of cancer is typically treated with whole-body therapies, some of which, such as chemotherapy, can have devastating and fatal effects.

The literature is very clearespecially in the last five to 10 yearsthat 90 percent of morbidity and mortality associated with cancer is when it spreads, Goodyear said. Thankfully, research has provided a good understanding of how this chemotherapy and radiation-induced metastasis process occurs.

Maximum tolerated chemotherapy actually induces the mechanisms to spread the cancer. In breast cancer, maximum tolerated chemotherapy will reduce the primary tumor, yet at the same time, cause it to spread to distant locations in the body.

Other cancer therapies, such as radiation therapy, can also cause cancer. Sometimes even the surgeries to remove cancer and even biopsies to test for it can lead cancer to metastasize.

A lot of people that come to us, theyre so surprised. They ask, Why didnt I know about this? Why didnt I know that surgery can cause metastasis? Why didnt I know chemotherapy and radiation can cause metastasis?

The story of vitamin C demonstrates that the devil is in the details. Roughly 50 years ago, Linus Pauling demonstrated that intravenous (IV) vitamin C (10 grams per day for 10 days) improved cancer survival. Later, researchers at the Mayo Clinic tried to reproduce the results but didnt use IV vitamin C. They instead gave 10 grams orally and found no benefit.

In the academic battle that followed, Mayo won and for the next several decades, the conventional thought was that vitamin C doesnt work. That began to change in about the year 2000, when Dr. Ping Chen, a conventional oncologist, started looking into vitamin C and publishing papers on its pharmacokinetics.

Since then, there has been a combination of pushback against the idea that vitamin C works on the one hand and, on the other, growing research that points to vitamin Cs effects being as powerful as any drug.

Vitamin C does have drug-like effects, and I like to refer to it as a pharmaco-mimetic, but its still a natural biological molecule that cant be patented and hence cant be a drug. Also, to be clear, there are distinct differences between whole food vitamin C and ascorbic acid.

They really have two very different purposes. Whole food vitamin C isnt suitable for the treatment of cancer, but does wonders for general health support, as it interacts favorably with copper and iron in your cells and mitochondria. I only recommend and use high-dose IV vitamin C in cases of acute infection or illness, as it does have very potent drug-like effects.

Its actually inducing metabolic changes and epigenetics, Goodyear said. Thats the great thing about natural therapies. Conventional medicine will take an approach to kind of throw a monkey wrench into the bodys physiology to shut everything down without a holistic perspective of how that affects the whole body. Its a very compartmentalized approach.

A holistic approach is like a pebble thrown into a calm pool in the morning. Its effects ripple throughout the physiology of the body. That is the beauty of natural therapies.

Now in cancer and sepsis when were dealing with the major dysfunction found in cancer, where things have metabolically, genetically, immunologically gone off the rails, we have to come in and really work to turn the tide. Thats where the intravenous vitamin C delivery is required. Thats where the sodium ascorbate comes in because thats the only way were going to be able to change that tide.

When treating cancer, IV needs to be used because you simply cant take the high dosages required orally. Doses of more than 10 to 20 grams of ascorbic acid will cause loose stools when taken orally, but IV administration bypasses the limitation of the gut. It also allows the vitamin C to get directly into the blood to the extracellular fluid, into the tumor microenvironment, to penetrate the tumor and saturate the entirety of the tumor.

If you feel like youre coming down with an infection, such as a flu or cold, oral vitamin C is plenty adequate. Oral dosing of vitamin C, using a non-liposomal product, can double your blood level of vitamin C. Using liposomal vitamin Cwhich is what Ive been recommending for yearscan increase it threefold to fivefoldup to about 300 micromolar. So, liposomal vitamin C can make a big difference.

However, when youre dealing with cancer, you need a minimum of 1,000 micromolar, or 1 millimolar, in the extracellular fluid to kill cancer cells, which is why you really need to use IV. In the case of large tumors or significant cancer spread, much higher plasma concentrations are required.

While the dosage is highly individual to each patient, as a general benchmark, Goodyear typically starts at 1.5 grams per kilogram, which for the average person would be somewhere between 100 and 200 grams per dose, three times a week.

So to be clear, I dont advise taking ascorbic acid for daily vitamin C requirements. I strongly suggest that you use whole food vitamin C, which is far superior as a daily source.

Vitamin C has a wide variety of effects, which can be generally classified into the following: genomic, epigenomic, transcriptomic, proteomic, metabolomic, and immunomodulatomic.

The point here is that vitamin C is not just directly killing cancer cells, what we would call cytotoxic effects. Vitamin C is actually working to change the metabolism of the cancer, Goodyear said.

What that means is, it creates an energy crisis. It actually depletes the body of certain intermediates that make it so this cancer, which is addicted to sugar, cannot use [the sugar] efficiently to make energy, so it dies. It also depletes [the cancer] of its ability to detoxify.

So to be specific, research shows that vitamin C depletes the cancer of reduced glutathione. And getting rid of that glutathione in that cancer eliminates its ability to handle the high oxidative stress that this pro-oxidative vitamin C therapy induces, which kills the cancer cell.

It also disrupts how cancer makes energy. And its fascinating because everybody looks at this and they ask, Well, how will this affect my healthy cells? This is the paradigm changer with vitamin C.

The environmentas much as the dose, as much as the delivery, as much as the tumor saturationthe environment encountered by that vitamin C dictates the result as much as the dose itself. So you can induce a pro-oxidative effect, a detoxification crisis, an energy crisis, in cancer cells, and healthy cells do just fine.

When you think of vitamin C, youre probably thinking its an antioxidant, which is true. But in high doses only available through IV, it actually becomes a pro-oxidant, and thats what allows it to kill cancer cells and gives it its antiviral and antibacterial properties.

And theres plenty benefits of that. Thats why its so helpful in viral and bacterial infections. Its countering that cytotoxic burst found in infection. Its donating an electron and becomes oxidized [which neutralizes oxygen], Goodyear said.

He noted that this is why vitamin C can help people with sepsis, including COVID-19 sepsis, and the cytokine storm that causes most of the fatal lung damage resulting from severe COVID.

Its different effects are dictated by the different environmentsit can become pro-oxidative, Goodyear said.

When vitamin C is pro-oxidative, it has a helpful effect on cancer patients.

Its delivering the oxidative stress to the tumor and creating it through hydroxyl free radicals, hydrogen peroxide, superoxide anions, he said.

Goodyear also uses melatonin for cancer treatment and monitors patients melatonin levels to ensure proper dosage. Typically, patients will start off with IV melatonin at a dose of 10 to 20 milligrams daily for two weeks to get the level up as quickly as possible while simultaneously taking oral melatonin at a dose of about 60 milligrams per day. The oral dose is then adjusted based on body weight and other parameters.

Ideally, your blood level is supposed to peak at around midnight. So with that in mind, if youre going to do the oral dose, you want to take the highest dose right before bed, maybe 45 minutes before, and then right before bed, he said.

The other doses, if youre going to do it three times a day, would be maybe 10 a.m. and 4 p.m. You really want to keep it away from solar noon. Otherwise, youre going to [impair your] chronobiology.

Goodyear said they try to adjust the dosing of melatonin so it harmonizes with the patients sleep cycle, but the first priority is the cancer.

When patients come to us, so many of them are in an advanced stage, so in that acute setting, we have to use these therapies in combination and sequence, together, to really turn the tide against the cancer.

Goodyear said his cancer clinic sees mostly patients with metastatic cancer who have already had treatment.

In those patients, in a six-week or maybe eight-week cycle, we can see a significant reduction in tumor burden, he said.

Our goal is no evidence of disease, but were going to typically seein most of our patients, well over 50 percenta significant reduction in that tumor burden while theyre here with us. The after-care is very important to continue that process. What were talking about here is at least a 50 percent reduction in the tumor that you can see clinically, through labs and through imaging.

Many of our patients will come in where the breast is a whole tumor, [or] their spine lights up like a Christmas tree. So its not like we have a patient coming in and they have a small little nodule, OK? These are patients that have failed chemotherapy twice or more, [have had] surgery, radiation [and the cancer] recurred, not just once, but often two or even more times.

Its a tough spot to be in, but if we can set a goal of no evidence of disease and see a 50 percent reduction in these patients, hey, thats something that we can work with because were not destroying the body; actually were working to heal the body.

As mentioned earlier, most of the patients have destroyed much of their bodies innate healing ability through repeated toxic treatments, which makes holistic treatment far less effective. Once chemotherapy damages your immune system, it becomes extraordinarily difficult to treat it.

I know how panic-stricken one can get when given a cancer diagnosis, but if youre in the early to mid stages, you have virtually nothing to lose by going holistic first. Your chances of total remission will be far greater than waiting until all other treatments fail, and you may be able to save your breasts and other parts of your body that would otherwise be cut out.

To make his point, Goodyear offers the case history of a woman with bilateral breast cancer who had been told she needed a bilateral mastectomy, bilateral radiation with chemo, and lymph node dissectionsix to 12 months of brutal and toxic treatments that would have left her disfigured.

When I was talking to her before she came, I said, Let me tell you my approach. Since youve not had any treatment, if we take this in a healing perspective and through a holistic integrative approach, you may just save your breasts, and you may negate the need for any of those other harmful therapies.

And in fact, now shes over two years outcancer-free, no breasts removed, no lymph nodes removed. So here is a person who was headed down that road that would be life-changing in a negative way. We hit the pause button.

She took a chance to think; she took a chance to read. And then she said, You know what? I want a different approach. We addressed it with a holistic evidence-based, integrative approach and now she has both breasts and shes living cancer-free.

She even had COVID and did great. When the immune system is not destroyed, things work so much better, and full-dose chemo destroys the immune system.

Goodyear and I cover a lot more ground in this interview than Ive summarized here, so I encourage you to listen to the full interview online. You can also find more information at Brio-Medical.com.

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New drug screening tool to fight the next pandemic – EurekAlert

Posted: August 14, 2022 at 2:32 am

image:The DrugVirus.info 2.0 portal provides an integrative interactive resource for exploration and analysis of broad-spectrum antiviral drugs (BSAs) and BSA-containing drug combinations (BCCs). view more

Credit: Aleksandr Ianevski

Following two years of severe restrictions, everyone is eager to be done with the coronavirus pandemic. Its tempting to think that COVID-19 is history, but the coronavirus and other viruses will regularly resurface.

What will we do the next time we have a major outbreak?

A research team at the Norwegian University of Science and Technology (NTNU) has been working hard to figure out the answer to this very question for the past six months.

During the coronavirus outbreak, a lot of people thought that malaria medicine might work. It took time to show that it wasnt effective, and many patients died. Our solution can immediately determine which medicine will work or not, says Denis Kainov, a professor of medicine at NTNU.

The solution is simply to reuse and redesign active ingredients that are currently used against various illnesses like cancer or HIV.

Researchers have looked at more than 11000 active ingredients to find the medicinal mix that has the greatest potential to work. The researchers have incorporated information about the active ingredients into a digital system and created an algorithm that can pick out the best ones.

The digital system is openly available online. The solution can save millions of euros, more lives and help us avoid societal shutdowns.

But first a little background on what we are actually facing.

We dont have medicines for 200 viral diseases that can spread in humans, says Kainov.

In other words, we have no medication that can prevent the viruses from multiplying when they start to spread. Developing vaccines for a virus that has not yet spread in humans isnt possible since viruses are constantly mutating.

As with COVID-19, future outbreaks will have plenty of time to spread before a vaccine is readily available.

This is where the NTNU researchers come in with their reuse approach and a brand-new algorithm for developing antiviral drugs.

These are medications that attack the virus itself, and can knock it back right from the start.

Antiviral drugs simply prevent the virus from multiplying. The problem is that developing a new antiviral drug takes about 13 to 15 years and a staggering 20 million euros. Few such options therefore exist. Antiviral drugs currently make up only 4.4 per cent of 4051 approved drugs.

The researchers at NTNU have now investigated all the existing possible active ingredients against viruses. These are molecules that have gone through some of the phases on the way to eventually having medicinal value.

The researchers have created a digital system called Drugvirus.info.

The system will give pharmaceutical companies and other researchers a head start in developing new treatments. Instead of spending research funding over many years, they will be able to cut back their spending to one year. Instead of spending millions on a new treatment, the cost will drop tenfold. NTNUs system will also save companies enormous sums and save more lives.

The system checks what active ingredients already exist that can be reused and redesigned so that we can slow down new outbreaks in the critical phase before a new vaccine is developed, says Kainov.

Reference:Aleksandr Ianevski, Ronja M Simonsen, Vegard Myhre, Tanel Tenson, Valentyn Oksenych, Magnar Bjrs, Denis E Kainov, DrugVirus.info 2.0: an integrative data portal for broad-spectrum antivirals (BSA) and BSA-containing drug combinations (BCCs),Nucleic Acids Research, Volume 50, Issue W1, 5 July 2022, Pages W272W275,https://doi.org/10.1093/nar/gkac348

Nucleic Acids Research

Literature review

DrugVirus.info 2.0: an integrative data portal for broad-spectrum antivirals (BSA) and BSA-containing drug combinations (BCCs)

24-May-2022

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.

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Professor (with Head of Department potential), Department of Medical & Molecular Genetics job with KINGS COLLEGE LONDON | 304203 – Times Higher…

Posted: August 14, 2022 at 2:31 am

The Faculty of Life Sciences & Medicine (FoLSM) is one of Europes largest and most prestigious centres for biomedical education and research. A powerhouse of discovery and innovation, our collective ambition is to deliver tangible improvements to patient care, population health and societal wellbeing. Our vibrant community is comprised of six Schools and a Centre for Education, over 1,200 academic and research staff, and over 6,000 talented students. The Faculty has developed strong links in both education and research with the other health related faculties and more broadly across the College to enable truly interdisciplinary and innovative approaches.

The School of Basic & Medical Biosciences within FoLSM now seeks to hire a Professor within the Department of Medical & Molecular Genetics. The department is home to 17 academic groups with a wide range of research interests and expertise across lab based and computational genetics and from basic discovery to clinical translation. There is an expectation that the successful candidate will carry out cutting edge research in their field, preferably human clinical genetics, so that we may better address the challenges of disease among all populations. The appointee will be an academic leader with significant experience in attracting research funding as PI and in publishing high quality outputs. Experience of fostering strong links with NHS providers would be advantageous.

Research and education at Kings benefits from multiple national and global partnerships and the Academic Health Sciences Centre (AHSC) of Kings Health Partners brings together world-class research, education and clinical practice for the benefit of patients. The Department shares the AHSCs commitment to ensuring faster translation and adoption of research innovation into clinical practice. The successful candidate will therefore bring the required skills to foster interdisciplinary partnerships that increase the reach of the Departments research and education and deliver impacts to benefit society.

The opportunity extends to applying for the role of Head of Department (3 years once renewable term) should this be of interest. The Head of Department will play a leading role in developing the Department through personal mentorship and leadership. The appointee will foster a stimulating, innovative and inclusive environment, enabling students and staff to thrive and develop. Regardless of position(s) applying for, please note that all applicants must have a PhD.

For further information about the role please visit https://jobs.kcl.ac.uk/professor-medical-molecular-geneticsand to apply for this role, please go to the Kings Career pages to submit the specified documentation. Informal enquiries may be made to the Kings Search Team; please contact Sarah Fraser or Matthew Granger at kings-search@kcl.ac.uk

The deadline for applications is11.59pmonWednesday 21st September2022.Interviews will be held inNovember 2022.

FoLSM is proud to hold an Athena SWAN Silver Award, and we expect our community to be committed to embedding an inclusive environment that celebrates and enables the diversity of our students and staff in everything that we do.

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Professor (with Head of Department potential), Department of Medical & Molecular Genetics job with KINGS COLLEGE LONDON | 304203 - Times Higher...

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Kathy C. Cordes, a former Baltimore Sun artist who later worked at NASA’s Space Telescope Institute, dies Baltimore Sun – Baltimore Sun

Posted: August 14, 2022 at 2:31 am

Kathy C. Cordes, a former Baltimore Sun artist who later worked at NASAs Space Telescope Institute on the Homewood campus of the Johns Hopkins University, died of congestive heart failure July 29 at Gilchrist Center in Towson. The former longtime Ednor Gardens resident was 71.

Kath was very smart and could easily have been a doctor or a scientist, said Ann Feild, a former Sun artist and Space Telescope Institute colleague and a longtime friend.

She had a strong work ethic, keen research, editorial and problem-solving skills. She was a unique artistic talent who had the ability to do realistic renderings and computer graphics as well as whimsical illustrations, she said. Her talents straddled the arena of art and ever-evolving digital technology.

And what a mind she had. It was wide, deep and expansive. She was also funny as heck and had a fabulous sense of the absurd. And [she was] nobodys fool.

Bonnie J. Eisenhamer, former education program manager in the Office of Public Outreach at NASAs Space Telescope Science Institute, worked closely with Ms. Cordes.

Kathy was one of a kind. She was delightful, pleasant, conscientious and dedicated, Ms. Eisenhamer said. She always went the extra mile to make sure things were right and adhered to national education standards. She always wanted to balance the creative while at the same time meeting our obligations. Ive worked with many artists and not all can do that.

Kathy Cheryl Cordes, daughter of Kenneth L. Cordes, a DuPont Co. chemical engineer, and Margaret A. Cordes, a special education teacher, was born in Wilmington, Delaware, and raised in its North Graylyn Crest neighborhood.

Kathy Cordes was a lab tech before working as an illustrator.

As a youngster, she attended dance, aerobatics and ballet classes, and was curious, as always, even then, said a sister, Holly Cordes Haegele of Pike Creek, Delaware.

After graduating from Brandywine High School, where she had been an exemplary student and a member of the drama club, Ms. Cordes first attended East Carolina University before matriculating to the University of Delaware, where she earned a bachelors degree in plant science. She also obtained a masters degree in psychology from Columbia University.

Early on, however, she spent a few years meandering. Drawn to science, and loving gardening, she got a degree in plant science, according to a 2019 Broadmead Retirement Community profile in Hunt Valley, where she had moved that year. But Kathy always drew and while working as a lab tech at a molecular genetics lab, she submitted some drawings to an anonymous ad in a Washington newspaper, that led to a series of jobs in news graphics.

Ms. Cordes worked for a subcontractor for the National Institutes of Health laboratory in Frederick doing DNA sequencing.

Kath had natural art skills and obviously could make more money doing that than working in the lab, Ms. Feild said. She could do the most realistic portraits and beautiful nature drawings, and could also do 1950s-inspired retro illustrations.

Ms. Cordes launched her career as a news artist when she went to work for United Press International in Washington, and later took a similar position with the The Mercury News, a newspaper in San Jose, California.

She returned to the East Coast and worked briefly for The Washington Times before joining The Sun as a staff artist and illustrator in the mid-1980s.

Twelve years later, Ms. Cordes joined the Office of Public Outreach at the Space Telescope Institute, home of the Hubble and James Webb space telescopes.

There Ms. Cordes worked closely with scientists and educators to convey complex astrophysics data to the lay public with graphics for the web and print publications, Ms. Feild said.

One of Ms. Cordes jobs was designing online teaching tools for Amazing Space a website for teachers and children. She considered it a dream job because it blended science, art and education, according to the Broadmead profile, and another favorite project was working on The Star Witness, a kids astronomy newspaper.

Vernon L. Simms was the chief of staff for the late U.S. Rep. Elijah E. Cummings and also owned and operated a home improvement business.

Kathy was a special woman for sure, Ms. Eisenhamer wrote in an email. She could take a badly drawn idea I had and bring it to life. She always connected to what we needed even when we didnt know ourselves. She made work easier and a more enjoyable place to be.

Kathy had a passion for science and education and she believed in what she did. She was simply the best of the best.

Stratis Kakadelis, former deputy head of the Office of Public Outreach, was another close colleague.

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Kathy had exacting standards of her own no matter how low yours were. You couldnt have anyone better to work with, Mr. Kakadelis said. She did so much to bring the excitement of Hubble discoveries to students and educators. She really had a worldwide impact.

Mr. Kakadelis said they also shared concern caring for older parents.

[Jeffrey Martin Arnstein, an antiques restorer, dies]

Id get to work early and Kathy was always there, he said. She had a sofa chair in her office and Id plop down and we talked, not about work, but of the difficulties of caring for elderly parents. The humanity in her was amazing.

A tall and angular woman with thick gray hair and a face that was highlighted by rimless glasses and brightened by a seemingly endless welcoming smile, Ms. Cordes was an avid gardener who had turned her Rexmere Road home in Ednor Gardens into a floral showplace.

Other pastimes included gesture drawing, paper arts, shadow puppets, origami boxes and reading, writing and watching the sky, according to the profile. She was also an animal lover and participated in animal rescue. She rescued her beloved dog Ernie from the Baltimore Beltway and countless cats who called her Rexmere Road rowhouse their home.

Plans for a celebration-of-life gathering this fall are incomplete.

In addition to her sister, Ms. Cordes is survived by another sister, Judith Kay McClintock of Arden, Delaware.

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