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Journal of Stem Cell Research and Therapy- Open Access …

Posted: July 26, 2018 at 3:45 pm

PUBMED NLM ID: 101586297 | Index Copernicus Value: 84.95 The Journal of Stem Cell Research & Therapy is an open access journal that showcases seminal research in the field of stem cell therapy. As stem-cells are flag-bearers of translational research, the field has an interdisciplinary feel by including oncology, clinical research, medicine and healthcare under the aegis of stem-cell therapy. It also includes scientific research related to the auxiliary areas of Biology by prioritizing scholarly communication milieu and transfers expert knowledge synthesized from the ever burgeoning stem-cell literature. In order to create such impactful content, the Journal of Stem Cell Research & Therapy brings together an expert Editorial Board, which comprises of noted scholars in the field of Cell Biology. Every single article is subjected to rigorous peer review by illustrious scientists. In addition to Research Articles, the Journal also publishes high quality Commentaries, Reviews, and Perspectives aimed at synthesizing the latest developments in the field, and putting forward new theories in order to provoke debates amongst the scholars in the field. The journal thus maintains the highest standards in terms of quality and comprehensive in its approach.The journal aims to provide the authors with an efficient and courteous editorial platform. The authors can be assured of an expeditious publishing process. In this regard, the journal also provides advance online posting of the accepted articles. The Journal of Stem Cell Research & Therapy ensures barrier-free, open access distribution of its content online and thus, helps in improving the citations for authors and attaining a good impact factor.

Scholarly Journal of Stem Cell Research & Therapy is using online manuscript submission, review and tracking systems of Editorial Manager for quality and quick review processing. Review processing is performed by the editorial board members of Journal of Stem Cell Research and Therapy or outside experts; at least two independent reviewers approval followed by editor approval is required for acceptance of any citable manuscript.

It is an undifferentiated cell which is capable of transforming into more cells of same type or multiple other types. They are found in multicellular organisms. They can differentiate into cells of blood, skin, heart, muscles, brain etc. In adult human being, they replenish the dead cells of various organs. Stem cells are being used for treatment of various diseases like diabetes, arthritis, few cancers, bone marrow failure etc.

Related Journals of Stem Cell

Insights in Stem Cells, Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biology,Stem Cells, Cell Stem Cell, Stem Cells and Development, Stem Cell Reviews and Reports, Current Stem Cell Research and Therapy, Stem Cell Research

They can develop into any cell type or organ in the body. A single totipotent stem cell can give rise to an entire organism. Fertilized egg or a zygote is the best example. Zygote divides and produces more totipotent cells. After 4 days the cells lose totipotency and become pluripotent.

Related Journals ofTotipotent Stem Cells

Breast Cancer: Current Research, Cancer Diagnosis, Reproductive Medicine, Genetics & Stem Cell Biology, Stem Cell Research and Therapy, Stem Cells International, Stem cells translational medicine, Current Protocols in Stem Cell Biology

They can differentiate into any cell type in the human body. Embryonic stem cells are mostly pluripotent stem cells. They have the ability to differentiate into any of three germ layers: endoderm, mesoderm, or ectoderm.

Related Journals ofPluripotent Stem Cells

Cancer Science & Therapy, Cervical Cancer: Open Access, Reproductive Medicine, Genetics & Stem Cell Biology, Stem Cell Reports, Hematology/ Oncology and Stem Cell Therapy, Journal of Stem Cells, International Journal of Stem Cells

These are multipotent stem cells normally found in the bone marrow and are derived from mesenchyme. They differentiate into adipocytes, chondrocytes, osteoblasts, myocytes and tendon. MSCs can also be extracted from blood, fallopian tube, fetal liver and lungs.

Related Journals ofMesenchymal Stem Cells

Insights in Stem Cells, Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biology, Journal of Stem Cells and Regenerative Medicine, Stem Cells and Cloning: Advances and Applications, International Journal of Hematology-Oncology and Stem Cell Research

They are the multipotent stem cells derived from mesoderm and located in red bone marrow. They are responsible for production of red blood cells, white blood cells and platelets. HSCs give rise to myeloid lineage (which forms erythrocytes, eosinophils, basophils, neutrophils, macrophages, mast cells and platelets) and lymphoid lineage (which forms T-lymphocytes, plasma cells and NK cells).

Related Journals ofHematopoietic Stem Cells

Insights in Stem Cells, Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biology, International Journal of Hematology-Oncology and Stem Cell Research, Open Stem Cell Journal, Stem Cell, Stem Cell Research Journal

They can differentiate into more than one cell type, but only into a limited number of cell types. Hematopoietic stem cells are considered multipotent as they can differentite into red blood cells, platelets, white blood cells but they cannot differentiate into hepatocytes or brain cells.

Related Journals ofMultipotent Stem Cells

Cancer Medicine & Anti Cancer Drugs, Colorectal Cancer: Open Access, Reproductive Medicine, Genetics & Stem Cell Biology, Blood, Journal of Cerebral Blood Flow and Metabolism, Biology of Blood and Marrow Transplantation, Pediatric Blood and Cancer, Blood Cells, Molecules, and Diseases, Blood Reviews

Cells with stem cell like abilities have been observed breast cancer, colon cancer, leukemia, melanoma, prostate cancer which can form new cells and lead to tumorigenesis. They cause relapse and metastasis by giving rise to new tumors. Scientists are developing methods to destroy CSCs in place of traditional methods which focus on bulk of cancer cells.

Related Journals ofCancer Stem Cells

Head and Neck Cancer Research, Lung Cancer Diagnosis & Treatment, Genetics & Stem Cell Biology, Cancer Research, Nature Reviews Cancer, Journal of the National Cancer Institute, Clinical Cancer Research, Cancer Cell, Cancer, International Journal of Cancer, British Journal of Cancer

They are derived from Hematopoietic stem cells. They differentiate into Erythrocyte progenitor cell (forms erythrocytes), Thrombocyte progenitor cell (forms platelets) and Granulocyte-Monocyte progenitor cell (forms monocytes, macrophages, neutrophils, basophils, eosinophils, dendritic cells).

Related Journals ofMyeloid Stem cells

Insights in Stem Cells, Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biology, Clinical Medicine Insights: Blood Disorders, Electrolyte and Blood Pressure, Integrated Blood Pressure Control, Indian Journal of Hematology and Blood Transfusion, Current Studies in Hematology and Blood Transfusion, Blood Research, High Blood Pressure and Cardiovascular Prevention, Blood Cancer Journal, BMC Blood Disorders, Blood Transfusion

They are the self-renewing, multipotent stem cells in the nervous system that differentiate into neurons, astrocytes and oligodendrocytes. They repair the nervous system after damage or an injury. They have potential clinical use the management of Parkinsons disease, Huntingtons disease and multiple sclerosis.

Related Journals ofNeural Stem Cells

Oncology & Cancer Case Reports, Prostate Cancer, Reproductive Medicine, Genetics & Stem Cell Biology, Journal of Nervous and Mental Disease, Cortex; a journal devoted to the study of the nervous system and behavior, Child's Nervous System, Journal of the Peripheral Nervous System, Central Nervous System Agents in Medicinal Chemistry

They are derived from embryo in the blastocyst stage. They are pluripotent stem cells. They give rise to all derivatives of the three primary germ layers: endoderm (stomach, colon, liver, pancreas, intestines etc.), mesoderm (muscle, bone, cartilage, connective tissue, lymphatic system, circulatory system, genitourinary system etc.) and ectoderm (brain, spinal cord, epidermis etc.).

Related Journals ofEmbryonic Stem Cells

Human Genetics & Embryology, Breast Cancer: Current Research, Reproductive Medicine, Genetics & Stem Cell Biology, Birth Defects Research Part C - Embryo Today: Reviews, Advances in Anatomy Embryology and Cell Biology, Journal of Veterinary Medicine Series C: Anatomia Histologia Embryologia, Italian Journal of Anatomy and Embryology, Romanian Journal of Morphology and Embryology, Neuroembryology, Neuroembryology and Aging

Embryonic stem cells are derived from the fetus are used in treatment of various diseases. As ESCs are pluripotent, they can differentiate into any cell type. Researchers are able to grow ESCs into complex cells types like pancreatic -cells and cardiocytes. Fetal cell therapy is generating lot of controversy from religious groups and ethics committees.

Related Journals ofFetal Stem Cell Therapy

Insights in Stem Cells, Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biology, Archives of Disease in Childhood: Fetal and Neonatal Edition, Seminars in Fetal and Neonatal Medicine, Journal of Maternal-Fetal and Neonatal Medicine, Fetal Diagnosis and Therapy, Journal of Maternal-Fetal Medicine, Fetal and Pediatric Pathology, Fetal and Maternal Medicine Review, Journal of Maternal-Fetal Investigation, International Journal of Infertility and Fetal Medicine

Research is being done to use stem cells for the treatment of diabetes mellitus. Human embryonic stem cells may be grown in vivo and stimulated to produce pancreatic -cells and later transplanted to the patient. Its success depends on response of the patients immune system and ability of the transplanted cells to proliferate, differentiate and integrate with the target tissue.

Related Journals of Stem Cell Therapy for Diabetes

Endocrinology & Diabetes Research, Diabetes & Metabolism, Reproductive Medicine, Genetics & Stem Cell Biology, Diabetes Care, Diabetes, Diabetes, Obesity and Metabolism, The Lancet Diabetes and Endocrinology, Endocrine-Related Cancer, Best Practice and Research in Clinical Endocrinology and Metabolism, Journal of Endocrinology

The procedure to replace damaged cells (in cancers, aplastic anemia etc.) with healthy stem cells of the same person or in another compatible person to restore the normal production of cells. It can either be autologous or allogeneic. Bone marrow HSCs are generally used for the transplantation.

Related Journals of Stem Cell Transplant

Cancer Diagnosis, Cancer Science & Therapy, Cervical Cancer: Open Access, Gastrointestinal Cancer and Stromal Tumors, Genetics & Stem Cell Biology, Cell Transplantation, Journal of Cell Biology, Nature Reviews Molecular Cell Biology, Molecular Cell, Nature Cell Biology, Molecular and Cellular Biology, Cancer Cell, Current Opinion in Cell Biology

They are the totipotent, undifferentiated cells present in the meristems (shoot and root apices) of a plant. They never undergo aging process and can grow into any cell in the plant throughout its lifetime. They have numerous applications in production of cosmetics, perfumes, pigments, insecticides and antimicrobials.

Related Journals ofPlant Stem Cells

Plant Pathology & Microbiology, Plant Biochemistry & Physiology, Plant Physiology & Pathology, Genetics & Stem Cell Biology, Plant Cell, Plant Physiology, Plant Journal, Trends in Plant Science, Current Opinion in Plant Biology, Plant, Cell and Environment, American Journal of Transplantation, Plant Molecular Biology

Several types of dental stem cells have been isolated from mature and immature teeth, exfoliated deciduous teeth and apical papilla, MSCS from tooth germs and from human periodontal ligament. They are found to be multipotent and can give rise to osteogenic, adipogenic, myogenic and neurogenic cell lineages.

Related Journals of Dental Stem Cells

Oral Health and Dental Management, Research & Reviews: Journal of Dental Sciences, Dental Implants and Dentures: open access, Genetics & Stem Cell Biology, International Endodontic Journal, Dental Materials, Caries Research, Journal of Endodontics, Monographs in Oral Science, Molecular Oral Microbiology, Journal of Dentistry,International journal of oral science

Adipose tissue is a huge source of mesenchymal stem cells which differentiate into various cell types. They can be easily extracted in large numbers by a simple lipo-aspiration. They have good application potential in regenerative medicine. ASCs are found to have the ability to differentiate into bone cells, cartilage cells, nerve cells, adipocytes etc.

Related Journals of Adipose Derived Stem Cells

Childhood Obesity, Obesity and Eating Disorders, Reproductive Medicine, Genetics & Stem Cell Biology, International Journal of Obesity, Obesity, Obesity Surgery, Obesity Reviews, Diabetes, Obesity and Metabolism, Diabetes, Obesity and Metabolism, Surgery for Obesity and Related Diseases, Pediatric obesity

Preservation of stem cells is critical for both research and clinical application of stem-cell based therapies. Properly preserved stem cells can be later used in the field of regenerative medicine for treating congenital disorders, heart defects etc. Currently there is no universal method for preserving stem cells and the existing methods are expensive.

Related Journals ofStem Cell Preservation

Oncology & Cancer Case Reports, Prostate Cancer, Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biology, Journal of Stem Cells and Regenerative Medicine, Stem Cells and Cloning: Advances and Applications, International Journal of Hematology-Oncology and Stem Cell Research, Open Stem Cell Journal, Stem Cell, Stem Cell Research Journal

MSCs can be applied in osteoarthritis treatment through implantation and microfracture as well as intra-articular injections. Single injection studies have showed improvement from pain which decreased overtime. Multiple, regular MSC injections into joints may be necessary.

Related Journals ofStem Cell Therapy for Osteoarthritis

Osteoporosis and Physical Activity, Osteoarthritis, Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biology, Osteoarthritis and Cartilage, Arthritis and Rheumatism, Arthritis Care and Research, Arthritis Research and Therapy, Seminars in Arthritis and Rheumatism

OMICS International through its Open Access Initiative is committed to make genuine and reliable contributions to the scientific community. OMICS International hosts over 700 leading-edge peer reviewed Open Access Journals and organizes over 1000 International Conferences annually all over the world. OMICS International journals have over 10 million readers and the fame and success of the same can be attributed to the strong editorial board which contains over 50000 eminent personalities that ensure a rapid, quality and quick review process. OMICS International signed an agreement with more than 1000 International Societies to make healthcare information Open Access. OMICS International Conferences make the perfect platform for global networking as it brings together renowned speakers and scientists across the globe to a most exciting and memorable scientific event filled with much enlightening interactive sessions, world class exhibitions and poster presentations.

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Journal of Stem Cell Research and Therapy- Open Access ...

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Stem Cell Martinsburg West Virginia 25403

Posted: July 25, 2018 at 7:49 pm

Stem cell therapy has become a popular argument in the international medical scene. This highly questionable treatment has actually received blended opinions from numerous stakeholders in the healthcare industry and has actually also brought in the attention of politicians, religious leaders and the general population at large. Stem cell treatment is considered an innovative treatment for individuals dealing with a wide variety of degenerative conditions. Some typical questions concerning this treatment are answered listed below.

Are you a stem cell therapy specialist in Martinsburg WV 25403? Contact us for more information about joining our website.

Stem cells can be referred to as blank state or non-specialized cells that have the ability to become customized cells in the body such as bone, muscle, nerve or organ cells. This indicates that these special cells can be used to regrow or develop a large range of damaged cells and tissues in the body. Stem cell therapy is for that reason a treatment that aims at achieving tissue regeneration and can be utilized to treat health conditions and illnesses such as osteoarthritis, degenerative disc disease, spine injury, muscular degeneration, motor nerve cell disease, ALS, Parkinsons, cardiovascular disease and much more.

Being a treatment that is still under studio, stem cell treatment has actually not been fully accepted as a viable treatment choice for the above pointed out health conditions and health problems. A lot of studio is presently being carried out by scientists and medical professionals in various parts of the world to make this treatment practical and efficient. There are nevertheless different limitations imposed by federal governments on research including embryonic stem cells.

Currently, there havent been numerous case studies performed for this kind of treatment. However, with the few case studies that have been performed, one of the significant issues that has been raised is the increase in a clients threat of developing cancer. Cancer is triggered by the fast multiplication of cells that tend not to pass away so quickly. Stem cells have been related to comparable growth factors that might result in development of tumors and other malignant cells in patients.

Contact us for more information about stem cell provider in Martinsburg WV 25403

Stem cells can be extracted from a young embryo after conception. These stem cells are typically described as embryonic stem cells. After the stem cells are extracted from the embryo, the embryo is terminated. This is essentially among the significant reasons for controversy in the field of stem cell research study. Lots of people argue that termination of an embryo is unethical and unacceptable.

Stem cells can still be gotten through other methods as they can be discovered in the blood, bone marrow and umbilical cords of adult human beings. Typical body cells can also be reverse-engineered to become stem cells that have limited capabilities.

New studio has nevertheless revealed promise as researchers focus on establishing stem cells that do not form into growths in later treatment stages. These stem cells can therefore efficiently transform into other types of specialized cells. This therapy is therefore worth investigating into as lots of clients can take advantage of this advanced treatment.

Find a stem cell provider near Martinsburg WV 25403

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Main address:Martinsburg, West Virginia, 25403

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Stem Cell Martinsburg West Virginia 25403

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In Depth About Regenerative Therapy | Regen Colorado

Posted: July 25, 2018 at 7:44 pm

The Role of Unhealthy Joint Tissues in Osteoarthritis, and the Role of Stem Cells in the Cure

We now know that osteoarthritis (OA) is much more than just wear and tear. There are numerous maladaptive changes to a joint with OA. An osteoarthritic joint is besieged with substances that eat away at healthy hyaline (joint) cartilage. These are certain matrix metalloproteinases (MMPs) and interleukins secreted from the synovium (joint lining) of an arthritic joint. In addition, the native long chain hyaluronic acid molecules that help normalize and lubricate healthy joints is chopped into smaller, less effective pieces. In addition, the bone under the hyaline cartilage (subchondral bone) is inflammatory and structurally abnormal, and results in increased breakdown of hyaline cartilage because it is inflammatory and because it is not as good at absorbing and dissipating forces such as the force across the cartilage from walking or running. Here is a corroborating December 2017 article on the overall research and clinical benefits of stem cell therapy.

The link will take you to the full article:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745427/

If you dont have time for the entire article, here is the abstract:

World J Orthop. 2017 Dec 18;8(12):853-860. doi: 10.5312/wjo.v8.i12.853. eCollection 2017 Dec 18.

Paschos NK1, Sennett ML2.

Author information

Abstract

Cartilage disorders, including focal cartilage lesions, are among the most common clinical problems in orthopedic practice. Left untreated, large focal lesions may result in progression to osteoarthritis, with tremendous impact on the quality of life of affected individuals. Current management strategies have shown only a modest degree of success, while several upcoming interventions signify better outcomes in the future. Among these, stem cell therapies have been suggested as a promising new era for cartilage disorders. Certain characteristics of the stem cells, such as their potential to differentiate but also to support healing made them a fruitful candidate for lesions in cartilage, a tissue with poor healing capacity. The aim of this editorial is to provide an update on the recent advancements in the field of stem cell therapy for the management of focal cartilage defects. Our goal is to present recent basic science advances and to present the potential of the use of stem cells in novel clinical interventions towards the enhancement of the treatment armamentarium for cartilage lesions. Furthermore, we highlight some thoughts for the future of cartilage regeneration and repair and to explore future perspectives for the next steps in the field.

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In Depth About Regenerative Therapy | Regen Colorado

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The Transhumanist Wager: Zoltan Istvan: 9780988616110 …

Posted: July 24, 2018 at 10:43 pm

Man vs. machine, cryonics, mind uploading...a science fiction book that's Amazon's #1 book under the category Philosophy is The Transhumanist Wager. Istvan says religious people are challenged by transhumanists."-Fox News Channel

An unwieldy novel of ideas about a freelance philosopher named Jethro Knights who sails around the world to promote the need for life-extension research and winds up establishing a floating libertarian city-state called Transhumania--a regulation-free utopia of tech billionaires and rationalists--from which he wages an atheist holy war on a theocratic United States.-The New York Times

"The novel has been described as a modern version ofAtlas Shrugged."-Yahoo News

"The biggest novel on the transhumanist scene is Istvan's. 'The Transhumanist Wager' reads like Dan Brown's undergradudate thesis -- a rollicking plot setting out futurist thought, manifesto style." -The Spectator

"Protagonist Jethro Knights may become one of the grand characters of modern fiction." -Psychology Today

"Transhumanism is snowballing into an international movement. The current wave of debate surrounding the concept began withThe Transhumanist Wager."-Breitbart

"This book is an edgy riveting masterpiece that will long linger with anyone who reads it."-Serious Wonder

"An Ayn Rand-esque manifesto." -The New Yorker

"Best-selling and award-winning novel." -Reason

"The Transhumanist Wager tells the story of Jethro Knights, a philosopher who rails against democratic politics and becomes a revolutionary that seizes control of the world in order to enforce a global authoritarian transhuman regime."-BBC

"Istvan, a prominent transhumanist writer...enlightens me. In The Transhumanist Wager, transhumanists manage to launch the third world war."-The Telegraph

"The Transhumanist Wager envisions a radical future." -CBS News

"It's a dystopian story that imagines a Christian nation outlawing transhumanism prompting all the billionaires to retreat to an offshore sea-stead where they can work on their advances undisturbed."-The Times Magazine

"Many sayThe Transhumanist Wageris the newAtlas Shrugged."-Marin Magazine

"It's a page turner. Istvan knows how to tell a compelling story." -io9 / Gizmodo

"IenjoyedThe Transhumanist Wager...an adventurous suspense-filled semi-sci-fi about sailing, love, and life extension." -The Huffington Post

"About a man's quest to live forever using science, medicine, and technology."Popular Science

Thrilling...an important literary work that everyone should read."-Guardian Liberty Voice

"Bestselling The Transhumanist Wager& famous transhumanist Zoltan Istvan...a new philosophy, a new psychology, a new metaphysics...the concept of people taking a Transhumanist Wager is making a strong impact." -RT Television

"It's set in a dystopian near-future America in which transhumanists are on the verge of huge technological breakthroughs but are under attack from conservative politicians and radical Christian fundamentalist terrorists."-Vox

"A gripping story...it's my new favorite novel."-Brighter Brains

"Istvan demonstrates great adeptness at crafting complex characters."-San Francisco Book Review

"The story is brilliant. It will challenge your thinking." -33voices

"Fascinating. It'smaking waves."-Good Day Sacramento, CBS TV

"Istvan's novel has the potential to become a cult book. I hope it will be widely read and discussed." -Kurzweil AI

"A philosophical manifesto...the world becomes ruled by scientists." -Vice (Italy)

"Strongly libertarian...a radical version of transhumanism."-Patheos

"The action sequences in the book are top notch."-New York Journal of Books

"The book asks a simple question: how far would you go to fight an anti-science world in order to live indefinitely through transhumanism? Protagonist Jethro Knights would start a world war - and does so in the book"-Wired UK

"The Transhumanist Wagerpromises to become a cult classic among futurists."-SASM Institute

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The Transhumanist Wager: Zoltan Istvan: 9780988616110 ...

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Stem Cells Lynchburg VA | Stem Cell Recovery SW Virginia

Posted: July 24, 2018 at 10:41 pm

The restorative properties of stem cells:

Stem cells are unique because they drive the natural healing process throughout your life. Stem cells are different from other cells in the body because they regenerate and produce specialized cell types. They heal and restore skin, bones, cartilage, muscles, nerves and other tissues when injured.

As a result, amazing new medical treatments are being developed to treat a range of diseases contemporary medicine currently deems difficult or impossible to treat. Among them are:

While stem cells can be found in most tissues of the body, they are usually buried deep, are few in number and are similar in appearance to surrounding cells. With the discovery of stem cells in teeth, an accessible and available source of stem cells has been identified.

The tooth is natures safe for these valuable stem cells, and there is an abundance of these cells in baby teeth, wisdom teeth and permanent teeth. The stem cells contained within teeth are capable of replicating themselves and can be readily recovered at the time of a planned dental procedure. Living stem cells found within extracted teeth were routinely discarded every day, but now, with the knowledge from recent medical research, your Doctor provides you the opportunity to save these cells for future use in developing medical treatments for your family.

Aside from being the most convenient stem cells to access, dental stem cells have significant medical benefits in the development of new medical therapies. Using ones own stem cells for medical treatment means a much lower risk of rejection by the body and decreases the need for powerful drugs that weaken the immune system, both of which are negative but typical realities that come into play when tissues or cells from a donor are used to treat patients.

Further, the stem cells from teeth have been observed in research studies to be among the most powerful stem cells in the human body. Stem cells from teeth replicate at a faster rate and for a longer period of time than do stem cells harvested from other tissues of the body.

Stem cells in the human body age over time and their regenerative abilities slow down later in life. The earlier in life that your familys stem cells are secured, the more valuable they will be when they are needed most.

Accessible The stem cells contained within teeth are recovered at the time of a planned procedure: Extraction of wisdom teeth, baby teeth or other healthy permanent teeth.

Affordable when compared with other methods of acquiring and preserving life saving stem cells: Peripheral blood, Bone Marrow, Cord blood etc, recovering Stem Cells from teeth is the most affordable and least invasive.

Convenience the recovery of stem cells from teeth can be performed in the doctors office anytime when a healthy tooth is being extracted.

Ease of Use The recovery of stem cells from teeth does not add any additional time on to a planned procedure. Your doctor does not require any additional equipment or training.

Healthy dental pulp contains stem cells that are among the most powerful stem cells in the body and replicate at a faster rate and for a longer period of time than other types of stem cells.Stem cells from teeth show great promise for future regenerative medical treatments of neurodegenerative diseases, heart disease, diabetes, bone diseases and brain and nerve injuries.

Any extracted tooth with a healthy pulp contains stem cells. Wisdom teeth, baby teeth and other permanent teeth i.e. healthy teeth that are fractured and teeth recommended for extraction for orthodontic purposes are all candidates for stem cell recovery and cryopreservation.

Age does not seem to play a major factor. All extracted healthy teeth contain stem cells. The younger you are then the younger the cells and these may be more beneficial in future regenerative therapies.

Diseases of different severity or tissue defects of different size will undoubtedly require different amounts of stem cells to heal. Conceptually, the more teeth are banked, the greater the potential for sufficient stem cells to treat various diseases.

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Stem Cells Lynchburg VA | Stem Cell Recovery SW Virginia

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Florida – Stem Cells Transplant Institute

Posted: July 24, 2018 at 2:45 am

Stem cells are one of the most fascinating areas of biology today. But like many expanding fields of scientific inquiry, research on stem cells raises scientific questions as rapidly as it generates new discoveries. Although Florida has become a world-leader in stem cells research, the state is still in the clinical trial phase and therapies have not been legally approved yet. Stem Cells Transplant Institute in Costa Rica, is a great opportunity for you to access stem cells therapies for many diseases like Diabetes, COPD, Alzheimers Disease and many others, with the highest standard of quality. Apply now

Costa Rica has a unique geographic location, with beautiful pristine beaches, lush green mountains formed by past volcanic eruptions, dense rainforests, lakes, and rivers. All these help support one of the most diverse plant and animal life on the planet in addition to one of the best health care systems in the World. We want to offer our patients from Jupiter Island, Manalapan, Palm Beach, Naples, Key Biscayne, Sanibel a unique experience! Get more information about stem cells therapies in Costa Rica. Now

The World Stem Cell Summit will be held in West Palm Beach, Florida at the Palm Beach County Convention Center in 2016. The summit focuses on the latest scientific discoveries and research involving the use of stem cells. It attracts more than 250 scientists, business leaders, investors, policy-makers, patient-advocates and others.

Florida is one of the fastest growing bioscience regions in the world. With a strong base of biotechnology, medical devices and pharmaceutical companies, world-class research universities and some of the leading non-profit research institutes in the world, Florida has built a resource base to be a top bioscience destination. However stem cells therapies are not legally approved yet in Florida.

The Stem Cells Transplant Institute of Costa Rica specializes in the legal treatment of Neuropathy, Cardiovascular Disease, Myocardial infarction, Alzheimer, Parkinson, Lupus, Chronic Obstructive pulmonary disease, Diabetes, Rheumatoid Arthritis, Osteoarthritis, Knee Injury, Erectile Dysfunction and Multiple Sclerosis.

Extending life and improving the quality of ones existence are clearly part of our goals. Stem cell research and therapies vividly attest to the fact that the future is now. Floridas bioscience has a major role to play in this exciting transformation, not just regionally but nationally. You dont have to wait more to become a living-proof, at Stem Cells transplant institute we make available for you the best human resource and top technologies, to discover yourself the potential of stem cells. Get legally approved therapiesApply now

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Florida - Stem Cells Transplant Institute

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Bone Marrow Transplant | Durham, Raleigh, North Carolina …

Posted: July 24, 2018 at 2:44 am

Your Transplant Team

Your transplant team will include board-certified hematologists and medical oncologists, clinical pharmacists, specially trained nurses,dieticians, and social workers. They meet regularly to discuss your care, collect opinions, and offer the best recommendations for your needs.Your transplant coordinator will facilitate the appointments and coordinate your care. We also assist you in finding nearby housing during your weeks-longtreatmentand help you navigate through any financial and insurance concerns.

If you are receiving a transplant from a donor, a search to identify a donor will take place on your behalf with immediate family members and the National Marrow Donor Program. Arrangements will be made for the cells to be harvested. If you are receiving an autologous transplant,your stem cells will be harvested and frozen for your use after your conditioning regimen.

Chemotherapy alone or with radiation therapy kills any cancer cells in your body. This conditioning regimen also makes room in your bone marrowfor the transplanted cells to grow.You receive your stem cell transplant after you complete the conditioning regimen. The transplanted cells enter your bloodstream in a method similar to a blood transfusion.

We are one of the only programs in North Carolina where you will receive the majority of your care in our day hospital as anoutpatient. This allows you to live in the comfort of your own homeor nearby temporary residence. If you are eligible to receive your own cells, you may spend no time in the main hospital asan inpatient. If you receive donor cells,youmay spend a portion of your time in the hospitaland undergo your remaining transplant care as anoutpatient. We are currently leading the nation's first clinical trial to offer bone marrow transplant care in the home.

Before, during, and after your treatment, our cancer support services help you minimize the side effects of treatment and cope with the emotional and psychological effects of diagnosis and treatment. Following your transplant, you will receive supportive care in our daily clinic with medicines, monitoring for side effects, and symptom management. You will be required to stay at Duke or live locally for 30-90 days following your transplant. This ensures a safe recovery following your treatment. You will also be required to have a caregiver with you at all times.

Once you complete your treatment, you will be discharged back to the care of your localdoctor.Periodically, you will undergo tests, either here or with your doctor, to monitor your response to therapy and your major organ function.

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Bone Marrow Transplant | Durham, Raleigh, North Carolina ...

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USA College of Medicine – University of South Alabama …

Posted: July 24, 2018 at 2:42 am

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Research Interests Access to health care Actin cytoskeleton remodeling and the ARP 2/3 complex in cancer cell metastasis Anticancer activity of nonsteroidal anti-inflammatory drugs Autoimmunity Bacterial Physiology and Genetics Basic mechanisms and clinical pharmacology of pulmonary arterial hypertension Calcium signaling and autoantibodies in pulmonary endothelial barrier disruption Cancer drug discovery and development Cancer metastasis Cancer prevention through behavioral intervention Cancer progression and metastasis Cancer stem cells Cancer survivorship studies Cancers that are diagnosed late stage such as ovarian and pancreatic cancer Carcinogenesis and drug resistance Cardiac Physiology Cell cycle regulation and DNA replication Cellular mechanisms of DNA repair and metabolism Cellular metabolism and its relevance to health through balanced and informed vitamin supplementation Chemokine signaling in cancer progression, angiogenesis and metastasis Childhood, adolescent, and young adult cancers Clinical/preclinical studies in vaccine development Collateral Vessels Colorectal cancer Convergent role of enzymes and pathways in response to environmental Geno toxins and chemotherapy Developing new screening methods for issues such as complications of pregnancy DNA damage response and repair pathways (special focus on Fanconi anemia pathway and homologous recombination) DNA topoisomerases and their inhibitors Emerging viruses Endometrial Cancer Enzyme Binding and Kinetics Flow Cytometry Fostering health care networks Gene regulation Glycochemistry and pulmonary glycocalyx Health communications Health disparities Hematopathology Herpes simplex Eye Infections HIV-1 Host-Pathogen Interactions Identification of novel targets for cancer therapy Identifying proteomic biomarkers using proteomic and glycomic methods for the early detection and monitoring of cancer Immune Regulation Inflammation Influenza viruses Ischemic Preconditioning Laboratory of Infectious Diseases Lung injury and repair Mechanism of base excision repair Melanoma and non-melanoma skin cancer Metabolism and cancer Methods to improve the test for prostate cancer MicroRNA and cancer MicroRNAs in cancer Mitochondrial Disease and Cancer Molecular cancer therapeutics (identification of novel drug targets and therapeutics development) Molecular diagnosis, prognosis and sub-classification of cancer Molecular libraries screening and cellular imaging Natural products as cancer prevention and therapy agents Novel chemical entities as putatives anti-cancer lead compounds Obligate Intracellular Parasitism Ovarian Cancer Oxidative DNA Damage and Repair PARP and NAD+ metabolism in human cells Phosphodiesterases, cyclic GMP signaling, and apoptosis Posttranslational modifications (special focus on ubiquitin ligases and their role in DNA damage response and repair) Progression of pulmonary arterial hypertension (PAH) Pulmonary Immunology and Infections Regulation of transcription and RNA splicing in cancer stem cells Response of DNA repair pathways to damage induced by exposure to endocrine disrupting chemicals (EDCs) Role of cAMP-phosphodiesterases (PDEs) in the temporal and spatial control of cAMP signals Roles of non-coding RNAs in cancer development and progression Select Agents and Biodefense Sepsis SON-mediated constitutive/alternative RNA splicing and cancer Structural Biology including Macromolecular X-ray Crystallography and Small Angle X-ray Scattering Targeted cancer therapy Telehealth Therapeutic resistance Therapeutic resistance in cancer Tumor-stromal interactions Vaccine Development Vascular remodeling in lung circulation and its impact on blood flow pattering Viral transmission and pathogenesis Vitamin B3 (Niacin) metabolism and its impact on disease management, treatment and prevention

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USA College of Medicine - University of South Alabama ...

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New York & New Jersey – Stem Cell Therapy & Platelet Rich …

Posted: July 24, 2018 at 2:42 am

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If you have pain, we're here to help. Regenexx Procedures are patented stem cell and blood platelet procedures that are used to treat a wide range of joint and spine conditions.

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The Regenexx family of non-surgical stem-cell & blood platelet procedures are next generation regenerative injection treatments for those who are suffering from shoulder pain due to arthritis, rotator cuff and shoulder labrum tears, overuse injuries, and other degenerative conditions. Regenexx is also a viable alternative for those considering shoulder replacement surgery.

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Regenexx Procedures are advanced stem cell and blood platelet procedures for foot and ankle conditions. Before you consider ankle surgery, fusion or replacement, consider the worlds leading stem cell and prp injection treatments.

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The Regenexx family of non-surgical stem-cell & blood platelet procedures are next generation regenerative injection treatments for those who are suffering from pain or reduced range of motion due to basal joint / cmc arthritis, hand arthritis, or other injuries & conditions in the hand. View Details About Hand & Wrist Treatments Commonly Treated Conditions:

The Regenexx family of non-surgical stem cell and blood platelet procedures offer next-generation injection treatments for those who are suffering from knee pain or may be facing knee surgery or knee replacement due to common injuries, arthritis, overuse and other conditions.

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The Regenexx family of non-surgical stem-cell & blood platelet procedures are next generation regenerative injection treatments for those who are suffering from pain, inflammation or reduced range of motion due tocommon elbow injuries, arthritis and overuse conditions.

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The Regenexx family of hip surgery alternatives are breakthrough, non-surgical stem-cell treatments for people suffering from hip pain due to common injuries, hip arthritis & other degenerative problems related to the hip joint.

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Regenexx has many non-surgical platelet and stem cell based procedures developed to help patients avoid spine surgery and high dose epidural steroid side effects. These procedures utilize the patients own natural growth factors or stem cells to treat bulging or herniated discs, degenerative conditions in the spine, and other back and neck conditions that cause pain.

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Regenexx has many non-surgical platelet and stem cell based procedures developed to help patients avoid spine surgery and high dose epidural steroid side effects. These procedures utilize the patients own natural growth factors or stem cells to treat bulging or herniated discs, degenerative conditions in the spine, and other back and neck conditions that cause pain.

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New York & New Jersey - Stem Cell Therapy & Platelet Rich ...

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The Promise of Nanomedicine – Laboratory Equipment

Posted: July 23, 2018 at 9:42 am

More than a decade ago, nanotechnology became an integral part of the overall scientific research world. Governments started funding programs specifically aimed at nanotechnology, research universities opened their facilities and coursework to the new discipline, and journals focusing on nano research became commonplace.And now, many researchers believe, its nanomedicines turn to do the same. Nanomedicinewhich has emerged as nanotechnologys most important sub-disciplineis the application of nanotechnology to the prevention and treatment of disease in the human body. It is already having an impact clinically among some of the deadliest diseases in the world.

Nanomedicine is far from the stuff of science fiction. The possibilities for nanomedicine to help us diagnose, treat and image diseases are endless. Imagine a smart nanomedicine that is able to bind to tumor cells and enhance imaging and diagnosis, at the same time as being able to deliver a gene therapy or chemotherapy agent. With the technologies available to us and our multidisciplinary teams, this will be possible in my lifetime, said Phoebe Phillips, head of the pancreatic cancer translational research group at the University of New South Wales in Sydney.

Phillips and her team have created a nanoparticle that dramatically increases its effectiveness as an anti-cancer drug for patients with pancreatic cancers, which is one of the fastest killing cancers from time of initial detection, often leaving patients with no suitable treatment options and only weeks to live.

While nanomedicine canand likely willplay a role in diagnostics, regenerative medicine, prosthetics and more, the effect the sub-discipline is currently having on the treatment of autoimmune diseases and cancers is significant.

Nanomedicine for HIVThirty years ago, a diagnosis of HIV/AIDS was essentially a guarantee of a painful, protracted death. It wasnt until 1996 that researchers discovered antiretroviral drugs, and the potent combination therapy that leads to successful management of HIV/AIDS in most cases. However, not much has changed since that discovery. Those suffering from the autoimmune disease still require daily oral dosing of three to four pills, and chronic oral dosing has significant complications that can arise from the high pill burden experienced by patients, leading to non-adherence to therapies for a variety of reasons.

Ive been working in HIV for over 20 years, Andrew Owen, professor of molecular and clinical pharmacology at the University of Liverpool (UK) told Laboratory Equipment. I was trying to understand the variability in drug exposure that occurs between different individuals and the genetic basis for that. We were finding a lot of interesting things, but they werent clinically implementable. They gave us a good understanding of why drug exposure was variable, but it didnt actually help the patients in any way.

In an attempt to solve the problem rather than just characterize it, Owen turned to nanomedicine in 2009, eventually becoming part of the first team to conduct human trials of orally dosed nanomedicines for HIV. Since then, Owen and his interdisciplinary team at the Liverpool Nanomedicine Partnership have secured more than 20 million of research funding for a multitude of nanomedicine-based approaches to HIV, such low-dose oral delivery, long-acting injectable medications and targeted delivery of antiretrovirals.

Some of Owens most important research to date tackles two of the pharmaceutical industrys biggest challenges: oral delivery of potent drugs and supply and demand.

One of the major problems that has plagued drug discovery and drug development over the last 30 years has been compatibility with oral drug delivery, Owen explained. The pharmaceutical industry has wrestled with that because they can develop very potent molecules across diseases, but actually delivering those molecules orally is very challenging. As you try to design into the molecule oral bioavailabilty, you usually get further away from the potency you want.

The Liverpool team solved this problem with the creation of Solid Drug Nanoparticles. The technology consists of combining a normal drug, in its solid form, with particles on that drug that are measurable within the nanometer scale. There are other things packed into the formulation as well, such as FDA-approved stabilizers that are proven to help disperse the drug. Owen says it is all about increasing the surface area covered by the drug.

If you imagine you take a granulated form of the drug, youre going to get big chunks of drugs in the intestinal tract when dissolution happens. But if you have nanometer-sized particles within the GI tract, then you are going to get a complete coating of the inside of the intestine after you take the drug, Owen explained. What that does is it massively increases the surface area covered by the drug, which saturates all sorts of drug influx processes within the GI tract.

Since 80 percent of a humans immune system is concentrated in the gut, the Solid Drug Nanoparticles are the perfect mechanism. The immune cells in the gut instinctually move toward the particles, creating a pathway for the drugs to cross the intestines, move through the lymphatic system, and finally into the systematic circulation.

In February, Owen presented the results of two trials at the Conference on Retroviruses and Opportunistic Infections (CROI) that confirmed his Solid Drug Nanoparticles can be effective at a 50 percent dose reduction. Specifically, Owen and his team applied the nanomedicine-based approach to the formulation of two drugs: efvirenz (EFV) and lopinavir (LPV). EFV is the current WHO-recommended regimen, with 70 percent of adult HIV patients in low- and middle-income countries taking the medication. At 50 percent of the dose, the patients in the trial were able to maintain plasma concentrations of the conventional dose.

Globally, the supply of drugs needed to treat every patient with HIV is outstripping manufacturing capabilitymeaning we, as a human species, cannot physically make enough HIV medication to treat everyone with the disease. A 50 percent reduction in dose means twice as many patients served with the existing drug supply.Owen and his team are working with multiple global partners to move the technology forward. For the drugs already formulated, the Medicines Patent Pool and Clinical Health Access are helping to scale up and take them to market. Meanwhile, USAIDs Project OPTIMIZE is applying the nanoparticle technology to the newest HIV drugs for use in low- and middle-income countries.

For their latest collaboration with Johns Hopkins University, the Liverpool team was just awarded $3 million to examine the use of implantable technologies that can deliver drugs for weeks, or even months.

The current oral drug regimens for HIV comprises three drugs in combinationone is the major driver for efficacy, and the other two are nucleoside reverse transcriptase inhibitors that prevent resistance to the main drug. However, current injectable formulations are only available with the main drugnone include the nucleoside reverse transcriptase inhibitors.

So, our project aims to develop the first long-acting injectable nucleoside reverse transcriptase inhibitors so that we can use them to have a fully long-acting regimen that matches the current clinical paradigm for therapy, Owen said.

The Liverpool/Hopkins team has also thought about applying their long-acting injectable technology to other chronic diseases, such as malaria and tuberculosis, as well as some cardiovascular applications.

Nanomedicine for diabetesWhen the nanoparticles he was working with as an imaging tool didnt produce the desired results, Pere Santamaria grew frustratedbut he didnt give up. Instead, the doctor and professor at the University of Calgary (Canada) changed his assumptions and pursued his experimentuntil the data came pouring in that confirmed it wasnt a failed experiment at all. Rather, it was a discovery.

The discovery of Navacims was a bit serendipitous, Santamaria told Laboratory Equipment. Thankfully I am a little OCD and I didnt let the failed experiment go.Navacims are an entirely new class of nanomedicine drugs that harness the ability to stop disease without impairing normal immunity. Santamaria has been studying Navacims for the past 17 years, ever since unintentionally developing them. He even started a spin-off company, Parvus Therapeutics, Inc., to help bring the drugs to market.

In autoimmune diseases, white blood cells, which are normally responsible for warding off foreign invaders and disease, turn on the body, attacking the good cells and causing their destruction. Each specific autoimmune disease results from an attack against thousands of individual protein fragments in the targeted organ, such as the insulin-producing pancreatic cells in the case of type 1 diabetes.

But Santamarias studies show that nanoparticles decorated with protein targets acting as bait for disease-causing white blood cells can actually be used to reprogram the cells to rightfully suppress the disease they once intended to cause.

Once the immune system recognizes the presence of a Navacim, a white blood cell is reprogrammed by epigenetic changes into a lymphocyte that no longer wants to cause tissue damage, but rather work to suppress disease. According to Santamaria, the reprogramming step is immediately followed by an expansion of that population of lymphocytesone now-good white blood cell dividing into a million.

Basically they turn the tables on the immune system, and then there is a very sophisticated series of downstream cellular events that arise from that reprogramming event that involves the recruitment of other lymphocytes and other cell types that completely suppress the inflammation in the organ that is being infected, Santamaria explained. This happens extremely efficiently and comprehensively. This is an approach that can efficiently, selectively and specifically blend a complex response without impairing basic immunity.

In addition, the design of Navacims is modular, meaning the nanomedicine can be applied to severalif not allautoimmune diseases, including multiple sclerosis and rheumatoid arthritis. Navacims can be altered to target different diseases by simply changing a small portion of the bait molecules on the nanoparticles. Santamarias studies have shown this to work in about seven autoimmune diseases thus far.

In April, Santamarias company Parvus entered into a license and collaboration agreement with Novartis for Navacims. Under the terms of the agreement, Novartis receives exclusive worldwide rights to use Parvus Navacim technology to develop and commercialize products for the treatment of type 1 diabetes, and will be responsible for clinical-stage development and commercialization. Parvus will still be responsible for conducting ongoing preclinical work in the diabetes area, with some research funding from Novartis.

Weve had such a long time to prove ourselves, that this is not a flash in the pan, that this is something serious and robust, Santamaria said. We know so much about the mechanisms of our actions, and so much granularity. I think there are no other drugs that have reached the clinic with this level of understanding. That was painful in the beginning for us, but in the end its going to be good.

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The Promise of Nanomedicine - Laboratory Equipment

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