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Work by Parkville High, Perry Hall High students to be featured at BCPS Independent Research Symposium – nottinghammd.com

Posted: June 3, 2020 at 6:44 pm

TOWSON, MDThe eighth annual Baltimore County Public Schools Independent Research Symposium can be viewed online this year beginning on Wednesday, June 3.

The symposium showcases original research conducted by students at five BCPS high schools during the 2019-20 school year. During this springs closure of school buildings due to the pandemic, students have engaged in remote learning facilitated by their library media specialists to create and record their research presentations at home. Students, parents, staff, and community members interested in supporting these students and learning more about the Independent Research Seminar course are invited to view the Virtual Symposium.

Students at Franklin, Hereford, Parkville, Perry Hall, and Western School of Technology high schools were selected to participate in the Independent Research Seminar elective course this year, based on their commitment to following an advanced research process to conduct in-depth original research. Student researchers worked collaboratively and independently under the guidance of their library media specialists, faculty advisors, and expert mentors.

Students used the process and resources provided in an online research framework to generate a research question, conduct a literature review, write a research proposal, and synthesize their findings to create a presentation for an audience. Research topics address a variety of subjects and are based on the students own areas of interest. High school administrators, counselors, and library media specialists interested in offering the Independent Research Seminar at their schools will find implementation resources available online.

The 2020 BCPS Independent Research Seminar students and their research topics are:

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Rebecca Angin, Grade 11, Parkville High School, Elitism in EducationLena Bell, Grade 11, Franklin High School, De-extinction of the ThylacineKaitlyn Beyer, Grade 11, Hereford High School, Genetic Engineering: Medical Marvel, or Medical Mistake?Kaitlyn Crowley, Grade 12, Hereford High School, Motherhood: To what extent are societal pressures placed on women to have children and what are the effects of these pressures?Linna Cui, Grade 12, Perry Hall High School, Music Therapy for Behavior and Cognition: Effects of Classical Music on the Progression of Alzheimers DiseaseFalon Gustin, Grade 12, Western School of Technology and Environmental Science, LGBTQ+ Representation in School Curricula and MediaMax Harris, Grade 11, Franklin High School, A Look Into Topology with a Theory on the Square Peg ProblemEthan Jacobson, Grade 12, Hereford High School, Potential for Serotonergic Psychedelics in Assisted PsychotherapyHafeez Mustafa, Grade 11, Western School of Technology and Environmental Science, The Role of Social and News Media on the Stock MarketMatthew Rubinstein, Grade 12, Franklin High School, Reforming the United States System of Campaign FinanceMahnoor Sarfraz, Grade 12, Perry Hall High School, How can the United States government implement regulations which will decrease the cost of prescription medicines for Americans?Jeffrey Thewsuvat, Grade 12, Western School of Technology and Environmental Science, Exploring the Subatomic World: Quantum Teleportation

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Work by Parkville High, Perry Hall High students to be featured at BCPS Independent Research Symposium - nottinghammd.com

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Resistance Genes to Latest Generation of Antibiotics Are Widespread – Technology Networks

Posted: June 3, 2020 at 6:44 pm

The latest generation of tetracyclines a class of powerful, first-line antibiotics was designed to thwart the two most common ways bacteria resist such drugs. But a new study from researchers at Washington University in St. Louis and the National Institutes of Health (NIH) has found that genes representing yet another method of resistance are widespread in bacteria that live in the soil and on people. Some of these genes confer the power to destroy all tetracyclines, including the latest generation of these antibiotics.However, the researchers have created a chemical compound that shields tetracyclines from destruction. When the chemical compound was given in combination with tetracyclines as part of the new study, the antibiotics lethal effects were restored.

The findings indicate an emerging threat to one of the most widely used classes of antibiotics but also a promising way to protect against that threat.

We first found tetracycline-destroying genes five years ago in harmless environmental bacteria, and we said at the time that there was a risk the genes could get into bacteria that cause disease, leading to infections that would be very difficult to treat, said co-senior author Gautam Dantas, PhD, a professor of pathology and immunology and of molecular microbiology at Washington University School of Medicine in St. Louis. Once we started looking for these genes in clinical samples, we found them immediately. The fact that we were able to find them so rapidly tells me that these genes are more widespread than we thought. Its no longer a theoretical risk that this will be a problem in the clinic. Its already a problem.

In 2015, Dantas, also a professor of biomedical engineering, and Timothy Wencewicz, PhD, an associate professor of chemistry in Arts & Sciences at Washington University, discovered 10 different genes that each gave bacteria the ability to dice up the toxic part of the tetracycline molecule, thereby inactivating the drug. These genes code for proteins the researchers dubbed tetracycline destructases.

But they didnt know how widespread such genes were. To find out, Dantas and first author Andrew Gasparrini, PhD then a graduate student in Dantas lab screened 53 soil, 176 human stool, two animal feces, and 13 latrine samples for genes similar to the 10 theyd already found. The survey yielded 69 additional possible tetracycline-destructase genes.

Then they cloned some of the genes into E. coli bacteria that had no resistance to tetracyclines and tested whether the genetically modified bacteria survived exposure to the drugs. E. coli that had received supposed destructase genes from soil bacteria inactivated some of the tetracyclines. E. coli that had received genes from bacteria associated with people destroyed all 11 tetracyclines.

The scary thing is that one of the tetracycline destructases we found in human-associated bacteria Tet(X7) may have evolved from an ancestral destructase in soil bacteria, but it has a broader range and enhanced efficiency, said Wencewicz, who is a co-senior author on the new study. Usually theres a trade-off between how broad an enzyme is and how efficient it is. But Tet(X7) manages to be broad and efficient, and thats a potentially deadly combination.

In the first screen, the researchers had found tetracycline-destructase genes only in bacteria not known to cause disease in people. To find out whether disease-causing species also carried such genes, the scientists scanned the genetic sequences of clinical samples Dantas had collected over the years. They found Tet(X7) in a bacterium that had caused a lung infection and sent a man to intensive care in Pakistan in 2016.

Tetracyclines have been around since the 1940s. They are one of the most widely used classes of antibiotics, used for diseases ranging from pneumonia, to skin or urinary tract infections, to stomach ulcers, as well as in agriculture and aquaculture. In recent decades, mounting antibiotic resistance has driven pharmaceutical companies to spend hundreds of millions of dollars developing a new generation of tetracyclines that is impervious to the two most common resistance strategies: expelling drugs from the bacterial cell before they can do harm, and fortifying vulnerable parts of the bacterial cell.

The emergence of a third method of antibiotic resistance in disease-causing bacteria could be disastrous for public health. To better understand how Tet(X7) works, co-senior author Niraj Tolia, PhD, a senior investigator at the National Institute of Allergy and Infectious Diseases at the NIH, and co-author Hirdesh Kumar, PhD, a postdoctoral researcher in Tolias lab, solved the structure of the protein.

I established that Tet(X7) is very similar to known structures but way more active, and we dont really know why because the part that interacts with the tetracycline rings is the same, Kumar said. Im now taking a molecular dynamics approach so we can see the protein in action. If we can understand why it is so efficient, we can design even better inhibitors.

Wencewicz and colleagues previously designed a chemical compound that preserves the potency of tetracyclines by preventing destructases from chewing up the antibiotics. In the most recent study, co-author Jana L. Markley, PhD, a postdoctoral researcher in Wencewiczs lab, evaluated that inhibitor against the bacterium from the patient in Pakistan and its powerful Tet(X7) destructase. Adding the compound made the bacteria two to four times more sensitive to all three of the latest generation of tetracyclines.

Our team has a motto extending the wise words of Benjamin Franklin: In this world nothing can be said to be certain, except death, taxes and antibiotic resistance, Wencewicz said. Antibiotic resistance is going to happen. We need to get ahead of it and design inhibitors now to protect our antibiotics, because if we wait until it becomes a crisis, its too late.ReferenceGasparrini et al. (2020). Tetracycline-inactivating enzymes from environmental, human commensal, and pathogenic bacteria cause broad-spectrum tetracycline resistance. Communications Biology. DOI: https://doi.org/10.1038/s42003-020-0966-5

This article has been republished from the following materials. Note: material may have been edited for length and content. For further information, please contact the cited source.

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Focus on the United Kingdom | 2020-06-01 – World Grain

Posted: June 3, 2020 at 6:44 pm

The UK grains sector faces enormous change after almost five decades operating under the European Unions Common Agricultural Policy. It also faces enormous potential disruption following the UK exit from the EU on Jan. 31, unless a new trade deal with the EU can be made by the end of the year. At the same time, the sector is coping with the problems caused by the coronavirus (COVID-19) pandemic, with supply chains disrupted and new challenges from the need to feed a population in lockdown.

The International Grains Council (IGC) projects the UKs 2020-21 grains production at a total of 19.7 million tonnes, down from 25.7 million the year before. The countrys wheat production is put at 10 million tonnes, down from 16.3 million in 2019-20. Barley production is forecast to rise to 8.4 million tonnes, up from 8.2 million.

The UKs rapeseed crop is forecast at 1.3 million tonnes in 2020-21, compared with 1.8 million in 2019-20.

The Agriculture and Horticulture Development Board (AHDB) on Feb. 27 published a forecast putting 2019-20 wheat imports at 1.050 million tonnes, down 808,000 on the year before because of greater supply.

It is worth noting that the fall in imported demand is expected to be driven by the animal feed and bioethanol sectors, the AHDB commented. Imported wheat usage by flour millers is expected to be marginally higher year on year.

The AHDB forecast barley imports at 52,000 tonnes, down 18,000 on larger domestic supply. Maize imports in 2019-20 are put at 2.3 million tonnes. While the pace of maize imports is expected to slow somewhat over the next few months, imports may begin to increase again at the end of this season and into the 2020-21 season, due to its relative price compared with domestic grains.

Trade sources put likely imports of wheat at 2.6 million tonnes in 2020-21, with barley imports at 60,000 tonnes. Imports of rapeseed are forecast at 600,000 tonnes.

According to the National Association of British and Irish Millers (nabim), there are 32 companies, with a total of 51 milling sites in the countrys flour milling sector. Thirty-one are members of nabim, with 50 sites between them accounting for 99% of UK flour production. The association puts the industrys annual consumption of wheat to produce flour at 5 million tonnes, with some 1.3 million to 1.5 million tonnes used by starch and bioethanol producers.

The COVID-19 pandemic and the lockdown that has accompanied it has forced the industry to change. Following representations from nabim, the government decided to relax working time rules to help ensure deliveries. It also recognized food industry workers as key, giving them access to childcare and education support, the association said in an April 3 statement. British schools are closed but remain open to care for children of key workers.

An early warning system also has been set up by nabim to give notice of problems before they become critical.

The grain supply and delivery sector, including nabim members, has agreed small changes in working practice that will help the flow of goods and accompanying documentation while respecting social distancing and the difficulty of distributing documentation while so many administrative staff are working from home, nabim said. The government has allowed extra time for some tests to be undertaken and, wherever possible, auditing is being conducted remotely.

One feature of the lockdown has been increased demand from consumers for bagged flour for home baking. A website has been set up by nabim to let consumers know where they can buy the size of bags normally only sold to catering outlets, which are now closed.

The UK left the EU on Jan.31. The country is currently in a transition phase, in which trade continues under the same terms as before, while a future relationship between the two is negotiated. The advent of the COVID-19 crisis means that the transition period, due to last until the end of 2020, is widely expected to be extended, although the British government, which would have to ask for an extension, is still, at the time of writing, insisting that it will stick to the planned timetable.

One aspect of the future that is causing particular concern for the milling industry is the arrangements for trade between the islands of Britain and Ireland. Although the northern part of Ireland is part of the UK, under the 1998 Good Friday Agreement, which brought piece to Northern Ireland after many years of turmoil, there must be no hard border between the UK and the Republic of Ireland on the island of Ireland. That means that a customs barrier is planned, within the UK. The government of Prime Minister Boris Johnson is pretending that the problem does not exist, and no checks will be necessary, ignoring an explicit reference in the UKs Withdrawal Agreement with the EU. The high level of integration between the food sectors in the two countries, particularly in milling, means controls, with a potential need for sanitary and phytosanitary checks, could be highly onerous.

Leaving the EU takes British agriculture out of the EUs Common Agricultural Policy, with its system of direct payments to support farming. Instead, in a bill introduced to parliament on Jan. 16, the government plans to create a system under which farmers are rewarded for providing public goods such as improved air and water quality, higher animal welfare standards, improved access to the countryside or measures to reduce flooding.

In England, direct payments will be phased out over a seven-year period, starting in 2021.

BIOFUELS and GMOs

The UK is currently using E5 gasoline, but the government has announced a move to E10, beginning in 2021. The country has two large ethanol plants, Ensus and Vivergo, both in the northeast. Only Ensus is currently operating, using wheat and maize.

In an April 9 report, the USDA attach in London explained how the British government appears to want to expand the use of GM crops in the country, but the continuing close trading relationship between the UK and the remaining EU countries makes a big change unlikely.

The report cites the July 2019 inaugural speech of Prime Minister Johnson who said: Lets liberate the UKs extraordinary bioscience sector from anti-genetic modification rules.

Under any scenario, the UKs departure from the EU will not change policy or trade in genetically engineered plants or animals in the short to medium term, the attach commented. The EU is the UKs largest trading partner and the UK will retain much EU food law for many years to come.

For most of the British public, genetic engineering in food is irrelevant. There are very few mainstream grocery products that contain GE as an outright ingredient and, with this invisibility, UK consumers consider the GM problem to have gone away.

Follow our breaking news coverage of the coronavirus/COVID-19 situation.

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Animal Genetics Market to Witness Growth Acceleration During 2018-2028 – Cole of Duty

Posted: June 3, 2020 at 6:44 pm

GLOBAL ANIMAL GENETICS MARKET: OVERVIEW

The global animal genetics market is likely to rise at a healthy growth rate over the assessment timeframe. Augmented consumption of protein extracted from animals is prophesized to favor the growth of the global animal genetics market in the forthcoming years. In addition, increasing populations generates massive demand for animal-based protein, which further benefits the market.

The global animal genetics market has been segmented on the basis of region and product and services. The sole objective of providing such an all-inclusive report is to offer a deep insight into the market.

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GLOBAL ANIMAL GENETICS MARKET: NOTABLE DEVELOPMENTS

The global animal genetics market has gone through a few developments in the last few years. These market developments make a manifestation of how and what is influencing the growth of the global animal genetics market. One such development is mentioned below:

SOME OF THE KEY MARKET PLAYERS OF THE GLOBAL ANIMAL GENETICS MARKET ARE

GLOBAL ANIMAL GENETICS MARKET: GROWTH DRIVERS

High Demand for Animal Protein Places the Market on a High Growth Trajectory

The global animal genetics market is estimated to experience considerable growth over the review period. Such stellar growth of the market is attributed to the augmented adoption of genetic technologies and strict implementation of animal welfare regulations.

Likewise, livestock population has witnessed a substantial rise together with awareness related to the existence of animal genetic disorders. Besides, the need to cater to the unmet demands of animal protein is likely to add fillip to the global animal genetics market over the forecast timeframe.

With an objective to produce better milk and food products, there has been an escalation in the research and development activities by several scientists. Genetic modifications are likely to emerge as another factor supporting the expansion of the global animal genetics market in forthcoming years.

The market is also prophesized to be fuelled by rapid expansion of urbanization and rise in population, which place massive demand for animal protein. Increased adoption of various advanced genetic practices like embryo transfer, artificial insemination (AI) for production of modified breed on a large scale is estimated to favor the market in the years to come.

On the other hand, the dearth of properly skilled technicians and professional with expertise in genetic services is estimate to impede the growth of the global animal genetics market in years to come. Furthermore, strict regulations related to genetic engineering of animals together with high cost of animal testing is likely to obstruct the growth of the market.

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GLOBAL ANIMAL GENETICS MARKET: REGIONAL OUTLOOK

Asia Pacific, the Middle East and Africa, South America, Europe, and North America comprise the major regions of the global animal genetics market.

Considering geographies, North America is likely to play a dominant role in the global animal genetics market over the assessment timeframe. Such regional supremacy is ascribed to the presence of a large number of well-known companies of the global animal genetics market. In addition, the presence of a well-established livestock industry is likely to propel the North America animal genetics market to prominence in the near future.

The global animal genetics market is segmented as:

Products and Services

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Integrative Medicine in Child Neurology: What Do Physicians Know and What Do They Want to Learn? – Physician’s Weekly

Posted: June 3, 2020 at 6:43 pm

Pediatric neurology patients frequently use integrative medicine; however, providers may feel uncomfortable or unfamiliar with these therapies. Child neurologist attitudes toward integrative medicine and educational needs in integrative medicine have not been assessed. A national, anonymous survey was distributed to Child Neurology residents (n=294) and program directors (n=71) to assess attitudes toward specific integrative medicine modalities, practices in discussing integrative medicine with patients, and perceived need for a curriculum on integrative medicine; 61 (17%) partially and 53 (15%) fully completed the survey. Comparative analyses applied chi-square and independent tests. Qualitative content analysis was performed on free text responses. Most providers surveyed consider mind and body practices safe (93% of respondents) and effective (84%), but have concerns about the safety of chiropractic manipulation (56% felt this was harmful), and the efficacy of homeopathy (none considered this effective). Few inquire about patient integrative medicine use regularly. Child Neurology residents are interested in further education on this topic.

PubMed

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Alternative and Complementary Treatments for Cancer – HealthCentral.com

Posted: June 3, 2020 at 6:43 pm

On this page:BasicsComplementary TreatmentAlternative Treatment EffectivenessSide EffectsCancer Cure ScansDiet and Exercise

Youve seen the headlines about natural medicine trends, from yoga to supplements to diet and exercise fads. When it comes to cancer, you want to know what will help you safely regain your health during treatment and after. But there are loads of competing, sometimes-confusing info to sift through. What can you trust? Well, you can start with us here at HealthCentral: We went to the experts to learn all the science-based truth on complementary care for cancer.

First, lets clarify how cancer comes to be: Cancer occurs when abnormal cells anywhere in your body grow out of control, due to mutations in their DNA. Normal cells divide, age and die predictably, copying DNA as they go. Cancer cells, however, dont follow those rules. Rather than die off, they mutate, replicate, and form tumors.

Whats known as the primary site of your cancer is the spot where these cells start growing, and that organ or area determines the type of cancer you have. When cancerous cells journey through your blood or lymphatic system (the network of tissues and organs that flush out toxins, waste, and other undesirables), the areas they invade are metastatic sites.

Note that a cell can be abnormal without being cancerous (also known as malignant). It could be benign (not cancer), or precancerous or premalignant (likely to become cancer). Through screening and testing, docs can determine exactly what youre dealing with.

That depends on what kind of cancer you have, what stage its in, and other factors. Treatment can include:

Doctors often try more than one treatment, spaced out over weeks and months, as they gauge how your body responds. Your doc might even start you on multiple treatments at the same time.

Youve probably heard of complementary care. Or maybe you know it as alternative care. You know a bit of what these treatments might include (youre thinking meditation, herbs, and maybe yoga?). But did you know that while complementary and alternative care are often lumped together (as CAM, Complementary and Alternative Medicine), theyre not the same?

Complementary medicine is used in addition to conventional cancer care. It can include products, practices, and healthcare systems outside of mainstream medicine. These methods dont cure cancer, but work in conjunction with conventional cancer treatments to help in a variety of ways, including pain management and emotional support. Many complementary medicine practices can be considered evidence-based medicine (scientifically studied in randomized controlled trials, the highest level of evidence that guides cancer care).

When complementary medicine works harmoniously with conventional medicine, its an approach known as integrative medicine, or integrated care, where physicians treat you holisticallymeaning caring for you as a whole patient, taking into account all facets of your cancer experience. These can include:

When integrative medicine is administered to treat cancer, its known as integrative oncology, a patient-centered, evidence-informed field of cancer care. It may include:

Alternative medicine, in contrast, is used in place of conventional medicine. Rather than going hand-in-hand with, say surgery and chemo, alternative medicine is done instead of those evidence-based cancer treatments.

A quick note: before you try any new approach during (and after) your cancer treatment journey, make sure to discuss it with your doctor.

If youve used or are considering using complementary medicine as a cancer patient, youre not alonea national survey found that 65% of respondents whod been diagnosed with cancer had used some form of it.

Theres good reason to explore complementary care if you have cancer. It can be part of your supportive carehelping where you need it, like soothing and calming your mind and body as you go through this challenging time. Indeed, research suggests that complementary medicine can assist by:

There are easily hundreds of complementary treatments for cancer, so weve selected a small sample to discuss here. Possibilities include:

Acupuncture: Theres substantial evidence that this ancient Chinese practice of using sterile needles to stimulate different areas of the body can help manage cancer treatment-related nausea and vomiting. It may also help relieve cancer pain and other symptoms, but theres not enough evidence yet to support that.

Herbs: Ginger, for instance, has been shown to help control nausea from chemotherapy when used with conventional anti-nausea medications. Just keep in mind that any supplements you consume can change your body physiologicallynothing you ingest is without the potential for adverse effects. For instance, herbs can impact blood sugar levels and the bloods ability to clot.

Massage therapy: Sure, it feels sublime, and it turns out to have additional benefits too: research suggests that massage therapy can help relieve some cancer symptoms including:

Just be careful not to have deep tissue massage near surgery sites, tumors, or any medical devices. And always tell your therapist about your cancer diagnosis.

Meditation: Mindfulness-based meditation has been shown to improve quality of life during treatment. How? Studies of cancer patients have revealed the following happiness-boosting benefits:

Supplements: Herbal supplements for cancer could potentially help manage side effects like nausea and vomiting, pain, and fatigue, but more scientific evidence is required to make safe decisions about the use of these supplements.

Yoga: Preliminary data of this ancient mind/body practice from India suggests that those who do yoga could see improvements in these areas:

Another benefit: It might help lessen fatigue in breast cancer patients and survivors. More study into the myriad benefits of yoga is needed.

Other approaches: These include hypnosis, relaxation therapy, and biofeedback, all of which might help manage cancer symptoms and treatment side effects, based on study results.

One thing to note about all of these approaches: they might not be covered by your health insurance. According to the American Cancer Society, major insurers, including Blue Cross and Medicare, are starting to cover some complementary treatments. On the list above, acupuncture is most commonly covered. Contact your insurer to see what complementary treatments, if any, are paid for. They might be able to direct you to local providers who are covered under your plan.

When the treatments we discussed earlier (and the hundreds of others that are offered) are used in place of conventional medicine, its known as an alternative treatment. Nearly 40%, or 4 out of 10 Americans, believes that cancer can be cured by alternative treatments, a 2018 survey of cancer patients and people without cancer, found. However, while research shows that complementary medicine can play an important role in conventional cancer medicine, the same hasnt been readily found for alternative treatment.

Case in point: in 2009, the Society for Integrative Oncology (the leading international organization for healthcare professionals and researchers working in the field of complementary therapies in cancer care) published guidelines for healthcare professionals when using complementary medicine.

The org reminded healthcare professionals and patients that unproven cancer treatment methods shouldnt be used in place of conventional options because delaying cancer treatment thats evidence-based and shown to work reduces the chance of remission/cure for cancer patients.

Its important to talk with your healthcare professionals about the risks of using alternative therapies so you can make an informed decision about whats best for your health.

There are definite side effects with CAM. You might think that because something is natural, its safe. But this isnt always the case. Arsenic is natural, for instance, but you wouldnt want to start taking it in large doses.

Another example: Chemotherapy has a multitude of side effects because it destroys both cancerous cells and healthy cells. Its been cited by many as harmful because its made from chemicals. But did you know, some forms of chemo come from nature? Three drugs (Vincristine, Vinblastine, and Vinorelbine) are derived from plant alkaloids and are made from the periwinkle plant (Catharanthus Rosea). Chemo drugs called taxanes (Paclitaxel and Docetaxel) come from the bark of the Pacific Yew tree (Taxus).

Know too that just because something is sold, doesnt mean its been vetted or approved for usefor safety or qualityby the U.S. Food and Drug Administration (FDA). The FDA doesnt regulate vitamins and supplements, so the onus is on us to do our best to source safe, trustworthy products.

Its vital to tell your cancer healthcare team about every treatment and therapy youre using for your cancer, whether its receiving acupuncture for nausea, going to the chiropractor for pain, adding St. Johns Wort to your supplement regime to help manage depression, or getting a massage to feel better.

If youre reluctant to be open with your doc, youre not alone: 29% of cancer patients did not disclose their CAM practices to their providers, according to one study. Secret-keeping could be downright dangerous. Lets use these four seemingly innocuous examples to illustrate why:

Being open with your doc--both before you start a complementary treatment and while youre on it--is key to helping it complement, rather than detract, from the conventional care youre receiving.

When you have cancer, you of course want a cure (as quickly and painlessly as possible, please). But that desire can leave you vulnerable to fake claims, especially in the alternative medicine space. Both the FDA and the Federal Trade Commission (FTC) regularly warn the public about fraudulent cancer treatments.

It can be hard to spot the signs of snake oil. Without a medical degree, how can you be wise to empty promises? Youll often see the same language used in cancer CAM scams, according to the FDA. These phrases should raise a red flag that a treatment is just too good to be true:

Heres how you can protect yourself while receiving evidence-based integrated care:

You might be wondering now: with all this talk of complementary and alternative medicine, what about food? And diet? And exercise? What role does it play in all this? Is there a cancer diet that could be a complementary treatment?

Turns out, theres a strong body of evidence that a healthy diet and regular physical activity are associated with a reduced risk of cancer. The scientific literature links nutrition to cancer prevention based on specific physiologic pathways, including reducing inflammation, regulating hormones, and preventing oxidative stress. Even after a cancer diagnosis, by making smart choices about what they put on their plate, patients can:

Food has power. To wield it, the American Institute for Cancer Research and American Cancer Society recommends you:

As for physical activity? While you should talk to your healthcare team about what kind and amount of exercise is safe during treatment, The American College of Sports Medicine (ACSM) has issued guidelines for physical activity for cancer survivors, suggesting 150-300 minutes per week of moderate to vigorous physical activity. Exercise is a real magic pill, helping to:

As you can imagine, all of these benefits that come along with being active are particularly important when youre trying to put cancer behind you. Resistance training, in particular, has been proven to improve:

Exercise, like so many CAM options, can help you both feel stronger and respond to treatment better. Just as with other types of complementary treatments, youll want to talk to your doc about how to integrate it, so you can reap the maximum benefits both from your lifestyle changes and your conventional cancer treatment.

Researchers have found that a healthy diet is associated with a reduced risk of cancer. Even if you have cancer, it can help lessen the impact of side effects and improve your quality of life. Studies link nutrition to cancer prevention based on specific physiologic pathways, including reducing inflammation, regulating hormones, and preventing oxidative stress. All to say that food matters.

Heres the thing: there are therapies that can help you go into remission (the period when your signs and symptoms of cancer are reduced). And some healthcare professionals consider cancer cured if it hasnt returned after five years (also called complete remission). Treatments that achieve a complete remission/cure can include therapies that come from a natural source, like some forms of chemo, which are derived from plant alkaloids. But anyone promising a natural cure for cancer that doesnt have evidence to back up that claim is likely pedaling bunk.

As weve discussed, herbs can be excellent complementary treatment in oncology for things like nausea, but any claim of curing cancer should be tempered by evidence-based medicine results (meaning, proof to back up those claims).

The American Academy of Dermatology warns that black salve isnt as safe as you might think, stating that it has never been proven to work. An article on the AADs website cites reports of bad outcomes for people who tried to treat their cancer (including melanoma) using black salve. The U.S. Food and Drug Administration (FDA) warns against products that are touted as cures for cancer without evidence: The FDA urges consumers to steer clear of these potentially unsafe and unproven products and to always discuss cancer treatment options with their licensed health care provider.

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Create a "healing" home with lighting, color and plants – AZFamily

Posted: June 3, 2020 at 6:43 pm

Creating a healthy, healing environment for our family is so important as we navigate the stress and anxiety of this time. 75% of the immune system is the result of environmental and lifestyle factors. Top Immune Health Expert, Board Certified Integrative MD Dr. Taz, shares easy ways to create a healing home by reducing toxicity and activating our senses.

HOW TO CREATE A HEALING HOME with Dr. Taz

1) Lighting: Create ambient, soft light with lots of natural light to help enhance mood and lower cortisol. Replace fluorescent bubs, led bulbs. Consider sun lamps. Natural light is the most beneficial to the body.

2) Color: Color can be healing and color influences our feelings. White color on walls, dcor and furniture leads to a feel of clean and serenity. Teal accents in a room or overall color scheme of a house are associated with purity, relaxation and calmness. If someone needs to benefit from being in a relaxing envornment considere adding teal to the room. Red embodies power, vitality, energy. Rooms that need to be productive can utilize having red incorporated into their dcor. Magenta provides emotional balance and Yellow gives off a sense cheerfulness. Depending on the room and purpose, consider color to make the most out of the space.

3) Air: Household plants reduce indoor air pollution. My favorite house plants include: Peace Lily, Ferns, Aloe, Snake Plants, and Lemongrass. All plants have different needs for growth so make sure when choose a plant it is in a place and environment where it thrives. Plants also give us a way to feel closer to nature and be connected to mother earth.

Dr. Taz Bhatia, M.D. is a board-certified integrative medicine physician and wellness expert, who gained national recognition as a best-selling author of the books, What Doctors Eat, The 21 Day Belly Fix, and Super Woman RX. Her integration of Eastern medical wisdom with modern science, along with her unique Power Type discovery, has led to featured segments on The Today Show, Dr. Oz, Live with Kelly & Ryan and eventually the premiere of own PBS special Super Woman RX with Dr. Taz.

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Create a "healing" home with lighting, color and plants - AZFamily

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This Wellness Visionary Lifted My Teams Spirit During The COVID Crisis – Forbes

Posted: June 3, 2020 at 6:43 pm

Photo Credit: Dr. Andrew Weil

My company isnt alone when it comes to the struggles related to COVID-19. Still, as a document management and workplace solutions company, at times it has felt especially rough. At imageOne, our revenue is heavily reliant on people physically being at an office. Fewer printed pages meant an inevitable drop in sales volume.

Once the realities of the crisis sank in, the leadership team came together for a marathon weekend of punching numbers and forecasting the potential financial impact of the pandemic. We all knew times would be tough. But we also knew that thanks to our core values and company culture that puts people first, wed get through this challenge stronger than ever.

First, we had to focus on our financial health. It's during times like these where our practice of open-book management, company-wide financial literacy, and transparency really shines. These practices both support the strength of our balance sheet plus offer the added bonus of building a team that fully understands our financials.

As a company that greatly values collaboration, this is invaluable. We asked our entire team to assist in every level of the decision-making process. Soon, we had dozens of actionable proposals, ideas, and strategies from innovative office products to untapped client basesmany of which have come to fruition and brought in new streams of income.

The team also organized fun ways to connect and support our mental and physical wellbeing while working from home. So far, weve held a lip sync battle, had a remote wine tasting, and hosted a Zoom newlywed game with a recently married team member, just to name a few things weve done together.

Were continuing to encourage everyone to keep practicing our favorite healthy life habitswhich we call the Simple Sixthrough video, online stretch breaks, and other social channels. Especially now, promoting self-care was essential.

And as an extra thanks, we wanted to bring in someone from outside of the company who had a unique perspective about these trying times. We reached out to Dr. Andrew Weil, a renowned expert of integrative medicine, a New York Times bestselling author, co-founder of True Food Kitchen and Matcha Kari, and past guest of my donothing podcast, to ask if hed chat with my team for a special Q&A.

To our surprise and delight, he said yes!

For one inspiring hour, we had the opportunity to put stress and uncertainty aside to ask this wellness legend anything that was on our minds. We heard everything from easy relaxation methods to the impact coronavirus might have on business to his favorite foods and drinks.

We got to take our minds off work, focus on something positive, and come together as one (via the internet, of course). In the end, we all left feeling more united, informed, grateful for the experience, and energized to tackle whatever came next.

With so much wisdom gleaned from Dr. Weils conversation, I thought itd be selfish not to share it. Here are some great questions from my team that Dr. Weil answered:

Just Breathe

Breathing is the only function that you can do completely consciously or completely unconsciously, says Dr. Weil. The theory of breath work...is that, by using your conscious system to impose certain rhythms on the breath, you can gradually induce those rhythms in the involuntary nervous system.

You can actually change heart rate, blood pressure, and digestive function by working with the breath.

The 4-7-8 Breathing Method

There's the 4-7-8 Breathing Method. It's very simple, and the whole family can do it together, says Dr. Weil. I recommend doing it at least twice a day. It takes about 30 seconds. I do it in the morning when I get up, in the evening, while going to bed, and then any other time during the day that I feel like doing it or I feel anxious.

He adds, [The 4-7-8 Breathing Method] is by far the most effective anti-anxiety measure that I've ever discovered.

Watch Dr. Weil demonstrate the 4-7-8 Breathing Method here.

More virtual connections

I expect that more people will work from home afterward, speculates Dr. Weil. We're becoming familiar with using Zoom and virtual teaching. In the past few years, when I've been traveling to give lectures, I was thinking, I'd much prefer to stay home and do this virtually than fly across the country.

[I think] thats probably a good thing. It seems very inefficient to physically travel...and we now have the technology to do it [virtually].

Fewer handshakes

I hear people saying that handshakes will be a thing of the past, says Dr. Weil. Before the 1918 flu pandemic, spitting was an acceptable cultural practice. Saloons had spittoons in them. After that, it was no longer culturally acceptable. Maybe things like handshakes will no longer be culturally acceptable either.

Everyone is different

There's a very broad spectrum of sensitivity to caffeine, says Dr. Weil. There are people who drink one cup of coffee in the morning and can't sleep at night. There are other people who drink a pot of coffee at night and it has no effect. You want to find out where you are on that spectrum.

I used to say I produced one miracle cure a week just by getting someone to stop drinking coffee, and that was everything from recurrent urinary tract infections to irregular heartbeats to GI problems to insomnia to anxiety. Strong coffee is a strong drug. Many people who use it are addicted and have a withdrawal syndrome if they stop.

How do I know if Im sensitive to caffeine?

You stop drinking it and see what happens, suggests Dr. Weil. It's amazing to see what happens. Typically [if youre addicted], 24 to 36 later, you get a pounding headache. You can become fatigued. I've seen people incapacitated by this, and they are relieved instantly by having anything with caffeine in it. It usually lasts 48 hours, and then you're through it.

Cut down on the news

Im really limiting my intake of newsespecially television news, says Dr. Weil. I recommend it to everyone. You must be very careful how much you let into your life. It can be a great source of anxiety, stress, and anger. It doesn't mean to not be informed, but just pay attention to the effect it has on your mood.

Try plant-based stress relievers

Valerian is a very safe sedative and has been used for centuries in Europe, says Dr. Weil. Its very good if you need to fall asleep. Cava is a good anti-anxiety agent. Theres peppermint tea for stomach distress. There's a number of things that are inexpensive, safe, and really work.

Keep up those healthy habits

Im trying to attend to my eating habits. Right now, many people are eating more than they would like to. Theyre eating foods that they probably normally wouldn't eat for some comfort and for stress relief. Be careful about that.

Have some fun

I am very delighted when friends send funny things like YouTube videos or movies to watch that make me laugh, says Dr. Weil. I think that's essential right now.

Want to learn more?Listen to theentire conversation withthe imageOne team andDr. Weil hereandlearn more aboutcommon health myths,whyintegrative medicine could change our health care system,how businesses are being affected by COVID-19,and more.You can alsowatch it hereon YouTube.

If you want to learn more about the Simple Six,download the healthy life tips hereandlisten to my recent podcastabout it. Id also love for you to follow me onLinkedInandTwitter.

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This Wellness Visionary Lifted My Teams Spirit During The COVID Crisis - Forbes

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Benefits, Safety, and Adjunct Modality Prevalences of Long-Term Botuli | JPR – Dove Medical Press

Posted: June 3, 2020 at 6:43 pm

Dion Diep,1 Jasmine Ko,2 John Lan,3 Kinga T Koprowicz,3 Gordon Ko3,4

1MD Program, University of Toronto, Toronto, ON, Canada; 2Department of Kinesiology, McMaster University, Hamilton, ON, Canada; 3Canadian Centre of Integrative Medicine, Toronto, ON, Canada; 4Division of Physical Medicine & Rehabilitation, Sunnybrook Health Sciences Centre, Toronto, ON, Canada

Correspondence: Gordon KoClinical Adjunct Lecturer, Division of Physical Medicine & Rehabilitation, Sunnybrook Health Sciences Centre, 2075 Bayview Ave, Toronto, ON M4N 3M5, CanadaTel +1416-480-4342Fax +1416-480-6885Email drgordko@rogers.com

Introduction: There is a paucity of long-term treatment benefit and safety data of botulinum toxin A (BTX-A) for cervical dystonia (CD) and myofascial neck pain syndrome (MPS). Additionally, the prevalence of adjunct modality uses during this period is unknown despite evolving practices.Objective: To assess and compare treatment benefit, safety, and adjunct modality prevalences of long-term BTX-A injections between CD and MPS patients.Design: Retrospective cohort study.Setting: Private practice tertiary care clinics in Toronto.Patients: Convenience sample of 37 (52.9%) CD and 33 (47.1%) MPS patients treated for a meanSD duration of 7.2 4.3 and 8.3 4.7 years, respectively.Interventions: BTX-A injections administered at least once yearly, for a duration longer than 1 year.Main Outcome Measures: Toronto Western Spasmodic Torticollis Rating Scales (TWSTRS) for disability and pain, Patient Global Impression of Change (PGIC) score, time to peak effect, duration of total response, adverse effects, and prevalence of adjunct modalities.Results: CD patients experienced improvements in TWSTRS disability (17.57 6.79 to 9.81 4.35, p< 0.001) and pain (14.61 3.08 to 9.05 3.49, p< 0.001) scores as well as PGIC score (52.00% 23.60% to 64.80% 23.60%, p=0.007). MPS patients experienced improvements in TWSTRS disability (15.86 7.70 to 10.07 7.01, p=0.01) and pain (15.25 4.09 to 10.85 4.49, p=0.01) scores. In both cohorts, there were no changes in time to peak effect and duration of total response. Adverse effects were minimal and self-limiting. Prevalences of adjunct modalities used by CD versus MPS patients were 28.13% versus 50.00% for anesthetic procedures, 23.08% versus 15.38% for image-guidance, 65.71% versus 56.25% for pectoralis minor injections, and 47.06% versus 53.13% for cannabis-use.Conclusion: There were demonstrated and comparable treatment benefit, safety, and adjunct modality prevalences. Our study is the first to demonstrate that long-term BTX-A injections for MPS, although commonly used off-label, can be effective and safe.

Keywords: botulinum toxin, cervical dystonia, myofascial pain syndrome

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License.By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

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Benefits, Safety, and Adjunct Modality Prevalences of Long-Term Botuli | JPR - Dove Medical Press

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Characteristics of COVID-19 Clinical Trials in China Based on the Regi | DDDT – Dove Medical Press

Posted: June 3, 2020 at 6:43 pm

Jihan Huang,1,* Yingchun He,1,* Qianmin Su,2 Juan Yang1

1Center for Drug Clinical Research, Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, Peoples Republic of China; 2Department of Computer in College of Electronic and Electrical Engineering, Shanghai University of Engineering Science, Shanghai 201620, Peoples Republic of China

*These authors contributed equally to this work

Correspondence: Jihan Huang; Juan YangCenter for Drug Clinical Research, Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, #1200 Cailun Road, Pudong New District, Shanghai 201203, Peoples Republic of ChinaTel +86 21 51322420Email huangjihan@shutcm.edu.cn; janeyang5006@163.com

Objective: This study aimed to evaluate the fundamental characteristics of coronavirus disease (COVID-19) clinical trials registered in China.Methods: COVID-19 clinical trials registered in China were analyzed from databases on ChiCTR and ClinicalTrials.gov. The study designs, samples, primary end points, and intervention measures were evaluated.Results: In total, 262 intervention clinical trials were retrieved on March 10, 2020. Overall, 181 (69.1%) trials involved two groups, 200 (76.3%) trials were randomized parallel trials, 24 (9.2%) trials were double blind, and 60.3% of trials included 100 participants. Sixty (22.9%) trials considered symptom improvement as the primary endpoint and 43 (16.4%) trials considered the rate or time at which the subjects became virus-free as the primary endpoint. Of 262 intervention studies, chemical drugs and biological products were studied in 105 (40.1%) intervention studies, of which antiviral drugs accounted for 15.3% and malaria drugs accounted for 8.4% of the studies. Among all trials, 27.9% of the studies used traditional Chinese medicine (TCM), 10.3% used cell therapy, and 5.0% used plasma therapy.Conclusion: This study is the first snapshot of the landscape of COVID-19 clinical trials registered in China and provided the basic features of clinical trial designs for the treatment and prevention of COVID-19 to offer useful information to guide future clinical trials on COVID-19 in other countries.

Keywords: COVID-19, clinical trial, interventional, randomized, blinding

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License.By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

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Characteristics of COVID-19 Clinical Trials in China Based on the Regi | DDDT - Dove Medical Press

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