CHICAGO. (Ivanhoe Newswire) -- Osteoarthritis is the most common form of arthritis in the U.S., affecting nearly 27 million adults. It is currently an incurable disease in which the joints deteriorate. Now, a therapy that has been used in eye surgery and to heal the skin of burn victims is being used for the first time in knees. This new form of treatment involves stem cells from amniotic fluid.
As a professional photographer, climbing up step ladders and walking down stairs are part of the daily grind for 65-year-old Linda Schwartz.
"There's constant activity; you're moving the whole time, really," Schwartz told Ivanhoe.
But the pain of osteoarthritis in both of her knees was making all that activity a little harder.
Schwartz detailed, "I tried cortisone shots. I had something called Euflexxa. I was sent to physical therapy twice. I mean, I did try acupuncture in my knees. But it didn't really seem to make a difference."
Adam Yanke, M.D., an orthopedic surgeon at Rush University Medical Center in Chicago, explained, "It's like the rubber on the tire. So as you start to lose the rubber in your tire and the rim hits the road, that's what happens when you have bone on bone arthritis and you've lost all the cartilage in your knee."
Dr. Yanke enrolled Schwartz in an experimental new therapy that involved injecting amniotic fluid that contained stem cells donated by healthy mothers into the knees of osteoarthritis patients.
"Between the two of those they're a potent anti-inflammatory and they also have growth factors that help promote healing or healthy growth of tissue," said Dr. Yanke.
It was by far the most effective pain treatment that Schwartz has tried. Unlike cortisone shots, there are no side effects. The pain relief has so far lasted up to a year.
"It was a very gradual feeling of it's a little bit better, it's a little bit better, and then realizing, wow, it's really pretty good," said Schwartz.
The one drawback is this therapy is not for patients whose arthritis is so bad it requires knee replacement surgery. Even though it's still in the experimental stage, Dr. Yanke offers the stem cell treatment to his patients. But at a cost of $2,200 a shot, it is not yet covered by insurance.
Contributors to this news report include: Cyndy McGrath, Supervising Producer; Jessica Sanchez, Field Producer; Milvionne Chery, Assistant Producer; Roque Correa, Editor.
MEDICAL BREAKTHROUGHS
RESEARCH SUMMARY
TOPIC: Stem Cell Therapy for Osteoarthritis
REPORT: MB #4213
BACKGROUND: Osteoarthritis, also known as degenerative joint disease or degenerative arthritis, is the most chronic condition in the joints, affecting 27 million Americans. This disease is an incurable one in which the tissue and bone in the joints deteriorate. Because the cartilage is a cushion between the bones, when this is lost a person can experience considerable pain, swelling and problems when moving the joint. This condition can affect people of any age, but it is more common in people over the age of 65. Some common risk factors include:
* Age
* Obesity
* Previous joint injury
* Overuse of the joint
* Weak thigh muscles
* Genetics
(Source: http://www.arthritis.org/about-arthritis/types/osteoarthritis/what-is-osteoarthritis.php)
TREATMENTS: Although there is no cure for osteoarthritis, there are several treatments that exist to treat it. Each treatment depends on the patient and the severity of the disease, but all focus on managing pain, stiffness and swelling; as well as joint mobility and flexibility. Some of these treatments are:
* Medications, like analgesics, nonsteroidal anti-inflammatory drugs, pills, cream and lotions
* Physical and occupational therapies
* Surgery
* Natural and alternative therapies like nutritional supplements, acupuncture, massages, physical activities, and weight management
(Source: http://www.arthritis.org/about-arthritis/types/osteoarthritis/treatment.php)
STEM CELL THERAPY: Stem cell therapy consists of a membrane product that also has amniotic fluid in it. They are usually used in eye surgery and to heal the skin of burned victims but now they're being used to treat osteoarthritis in an experimental therapy. The main goal of the trial is to demonstrate this is an adequate therapy for relieving inflammation in the joints. The therapy involves injecting amniotic fluid that contains stem cells donated by healthy mother into the knees of patients. Dr. Adam Yanke says it's too soon to tell if the stem cell therapy will actually help with growing back healthy tissue in order to avoid surgery, or if it will simply delay the process. Furthermore, the therapy can't be given to patients suffering from chronic arthritis and are in need of knee replacement surgery. Nevertheless, the treatment helps with pain relief, movement and there are no reported side effects.
(Source: Adam Yanke)
FOR MORE INFORMATION ON THIS REPORT, PLEASE CONTACT:
Deb Song
Media Relations
If this story or any other Ivanhoe story has impacted your life or prompted you or someone you know to seek or change treatments, please let us know by contacting Marjorie Bekaert Thomas at mthomas@ivanhoe.com
Original post:
HealthWatch: Stem Cell Therapy for Osteoarthritis - WeAreGreenBay.com
- Harnessing naturally occurring mutations for T-cell therapy: a potential new avenue to enhance treatment efficacy ... - Nature.com - May 3rd, 2024
- Replay wins IND clearance for PRAME T cell cancer therapy - Clinical Trials Arena - May 3rd, 2024
- Dr Oluwole on the Use of CAR T-Cell Therapy in Autoimmune Disorders - OncLive - May 3rd, 2024
- Cell Therapy is Now on The Table for Metastatic Melanoma - InventUM - University of Miami - May 3rd, 2024
- Coeptis Therapeutics Announces Poster Data Presentation at American Society of Gene & Cell Therapy (ASGCT) 27th ... - PR Newswire - May 3rd, 2024
- Bringing the science of cell therapy into autoimmune diseases - Bristol Myers Squibb - May 3rd, 2024
- Quell Therapeutics Highlights Clinical Potential of QEL-001 and its Multi-Modular Treg Cell Therapy Platform at the ... - Yahoo Finance - May 3rd, 2024
- The potential and promise for clinical application of adoptive T cell therapy in cancer - Journal of Translational Medicine - Journal of Translational... - May 3rd, 2024
- NK Cell Therapy IGNK001 Receives FDA Orphan Drug Designation for AML - OncLive - May 3rd, 2024
- Carbon Biosciences Announces Four Presentations at the American Society of Gene and Cell Therapy 27th Annual ... - PR Newswire - May 3rd, 2024
- CAR T-Cell Therapy Broadens Second-Line Treatment in LBCL - Targeted Oncology - May 3rd, 2024
- CAR T-Cell Therapy Market to Reach Valuation of USD 22.2 Billion By 2032: Astute Analytica - Yahoo Finance - May 3rd, 2024
- Multiply Labs and Wilson Wolf Corporation Collaborate to Automate G-Rex Bioreactor for Cell Therapy Manufacturing - Business Wire - May 3rd, 2024
- Mammoth Biosciences to Present at Annual Meeting of the American Society of Gene & Cell Therapy - Business Wire - May 3rd, 2024
- Ingenium Therapeutics Novel NK Cell Therapy Receives Orphan Drug Designation From FDA - PR Newswire - May 3rd, 2024
- Cell and gene therapy companies trip at scalability hurdle - Pharmaceutical Technology - May 3rd, 2024
- Panasonic and Shinobi team on cost-effective cell therapy tech - BioProcess Insider - May 3rd, 2024
- The Future of Cell and Gene Therapy Purification - The Medicine Maker - May 3rd, 2024
- BMS closes Redwood City cell therapy research site - Fierce Biotech - May 3rd, 2024
- FDA drafts two guidances on safety testing for cell and gene therapy products - Regulatory Focus - May 3rd, 2024
- Afamitresgene autoleucel as an effective T-cell therapy for synovial sarcoma and liposarcoma - Physician's Weekly - May 3rd, 2024
- ClearPoint Neuro to Present Novel Research and Exhibit at the 27th American Society of Gene & Cell Therapy Annual ... - GlobeNewswire - May 3rd, 2024
- What Lies Ahead? Shaping the Future of Cell and Gene Therapy - Genetic Engineering & Biotechnology News - May 3rd, 2024
- AskBio Announces Nine Presentations at American Society of Gene and Cell Therapy 27th Annual Meeting 2024 - GlobeNewswire - May 3rd, 2024
- Somite Therapeutics to Present at the 27th Annual Meeting of the American Society of Cell and Gene Therapy (ASGCT) - PR Newswire - May 3rd, 2024
- Cell Therapy Basics - February 21st, 2024
- FDA Approves Amtagvi, First Cell Therapy for Skin Cancer - BioPharm International - February 21st, 2024
- Cellenkos Approved to Proceed with CK0803 Neurotrophic T regulatory Cell therapy to Treat Second Cohort in ALS Trial - PR Newswire - February 21st, 2024
- Astellas and Kelonia enter CAR-T cell therapy collaboration worth over $800m - PMLiVE - February 21st, 2024
- Bridging Therapy With CAR T-Cell Therapy in LBCL - OncLive - February 21st, 2024
- FDA approves first cell therapy to treat aggressive forms of melanoma - NPR - February 21st, 2024
- Iovance, with approval of 'TIL' cell therapy, readies for complex launch - Yahoo Finance - February 21st, 2024
- Cancer treatment: FDA approves type of cell therapy for patients with late-stage melanoma - FOX 26 Houston - February 21st, 2024
- Pharmalittle: We're reading about weight loss drugs, a cell therapy for melanoma, and more - STAT - February 21st, 2024
- On heels of cancer cell therapy win, Peninsula biotech looks to raise $211M - San Francisco Business Times - The Business Journals - February 21st, 2024
- FDA approves cell therapy to treat melanoma - FOX 26 Houston - February 21st, 2024
- Toddler Beats Childhood Leukemia After Car T-Cell Therapy - City of Hope - February 21st, 2024
- FDA Approves First One-time Cell Therapy for a Solid Tumor - BioSpace - February 21st, 2024
- Iovance wins FDA approval for cell therapy - BioProcess Insider - BioProcess Insider - February 21st, 2024
- FDA Approves Iovance Cancer Treatment, the First Cell Therapy for a Solid Tumor - MedCity News - February 21st, 2024
- Promising target for CAR T-cell therapy leads to potent antitumor responses against cutaneous and rare melanomas - Medical Xpress - February 21st, 2024
- Reinforcing Cell Therapy with Microfluidic Cell Sorting - RegMedNet - February 21st, 2024
- Study finds interleukin-24 enhances CAR-T cell therapy's effectiveness against cancer stem cells - News-Medical.Net - February 21st, 2024
- Understanding CAR T-Cell Therapy: Balancing the Risks and Benefits - Medriva - February 21st, 2024
- Keeping Track: Iovance's Amtaqvi Approval Brings T Cell Therapy To Solid Tumors - Pink Sheet - February 21st, 2024
- Tevogen Bio Holdings Inc., a Cell Therapy Company, Announces Completion of Business Combination and is to be ... - Yahoo Finance - February 21st, 2024
- What is CAR-T cell therapy, used for cancer treatment? Experts explain - India Today - India Today - February 21st, 2024
- UPDATE: 2seventy splits once more, sending cell therapy pipeline to Regeneron in 'dramatic' change - FierceBiotech - January 31st, 2024
- Revolutionary CAR T-cell therapy shows promise in reversing age-related metabolic dysfunction - News-Medical.Net - January 31st, 2024
- BioCardia Pivots to Biomarker Strategy to Prove Heart Failure Cell Therapy Benefits - precisionmedicineonline.com - January 31st, 2024
- Sequencing With CAR T-Cell Therapy for LBCL - OncLive - January 31st, 2024
- Single-cell analysis of refractory anti-SRP necrotizing myopathy treated with anti-BCMA CAR-T cell therapy ... - pnas.org - January 31st, 2024
- Regeneron to acquire 2seventy's cell therapy pipeline - Yahoo Finance - January 31st, 2024
- Trial of cell-based therapy CK08031 finishes dosing 1st patients - ALS News Today - January 31st, 2024
- Exploring Gene and Cell Therapy Integration in Pharmacies - PharmaNewsIntel - January 31st, 2024
- HBS Alumna Fighting Cancer with a Novel Cell Therapy - MBA - hbs.edu - January 31st, 2024
- YUHS partners with KURE.AI Therapeutics for cell therapy development - KBR - January 31st, 2024
- Global CAR-T Cell Therapy Market Report 2024-2034: Accelerated Growth Fueled by Intensive R&D, Growing Medical ... - Yahoo Finance - January 31st, 2024
- Oricell Announces FDA Clearance of IND Application for OriCAR-017, a novel GPRC5D Targeted CAR-T Cell Therapy ... - PR Newswire - January 31st, 2024
- A new chapter in cell therapy: engineered B cells reach the clinic for the first time - Labiotech.eu - January 31st, 2024
- Harnessing the Dark Genome: New Approach Greatly Improves Cancer T-Cell Therapy - SciTechDaily - January 31st, 2024
- Cell therapies | Harvard Stem Cell Institute (HSCI) - November 16th, 2023
- Oncternal Therapeutics Participating in Oppenheimer & Co.’s Virtual Fireside Chat: Discussion of ROR1 CAR T Cell Therapy in Hematological... - April 15th, 2023
- Basal Cell Carcinoma Treatment - The Skin Cancer Foundation - January 4th, 2023
- Adoptive Cell Therapy - Cancer Research Institute (CRI) - December 27th, 2022
- National Medical Commission prohibits use of stem cell therapy to treat patients with autism - Hindustan Times - December 18th, 2022
- Tumor buster - where will the CAR-T cell therapy missile go? - December 18th, 2022
- Gilead lands new cell therapy for Kite in $225M Arcellx deal, providing global scale for future J&J-Legend showdown - FierceBiotech - December 10th, 2022
- Non-Small Cell Lung Cancer Treatment (PDQ)Patient Version - November 24th, 2022
- CAR-T Cell Therapy Program - Frequently asked questions - November 24th, 2022
- EdiGene Announces Completion of Last Patient Dosing in Phase I Clinical Trial of ET-01, its Investigational Gene-editing Hematopoietic Stem Cell... - November 24th, 2022
- Radiation Therapy for Non-Small Cell Lung Cancer - November 6th, 2022
- AvenCell to Present New Data from Lead Universal CAR T Cell Therapy Program at 64th American Society of Hematology Annual Meeting and Exposition -... - November 6th, 2022
- Instil Bio's stock falls 35% after disclosing the cell therapy company paused enrollment in clinical trials - MarketWatch - November 6th, 2022
- Creative Medical Technology Holdings Announces FDA Clearance of Investigational New Drug (IND) Application for AlloStem, a Novel Cell Therapy for the... - November 6th, 2022
- Photodynamic Therapy to Treat Cancer - NCI - October 29th, 2022
- Researchers at University Hospitals create a breakthrough in CAR-T cell therapy for cancer patients - News 5 Cleveland WEWS - October 29th, 2022
- Mustang Bio Announces Phase 1/2 Clinical Trial Data of MB-106, a First-in-Class CD20-targeted, Autologous CAR T Cell Therapy, to be Presented at 11th... - October 29th, 2022
- Gilead, working to improve cancer cell therapy, partners with California startup - BioPharma Dive - October 21st, 2022
- Allogene starts first pivotal trials of an 'off-the-shelf' cell therapy for cancer - BioPharma Dive - October 13th, 2022