Category Archives: South Carolina Stem Cells

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Cancer Stem Cells - University of South Carolina

Houston Texans officials gave outside linebacker Jadeveon Clowney a projected recovery time of nine months after microfracture surgery Monday on his balky right knee. But its too soon to say if Clowney can meet that projection or regain the explosiveness that made him the No. 1 pick in the 2014 NFL Draft, according to one expert.

The great part of this operation is, its really safe, said Dr. Brian Cole, section head of the Cartilage Research and Restoration Center at Rush University Medical Center in Chicago and team physician for the Chicago Bulls and White Sox. The bad part of this operation is it doesnt always work.

Clowney has had two operations on his right knee during his rookie season in the NFL a concerning development for pass rusher who relies on his legs to generate the speed and power needed to reach the quarterback. The 21-year-old missed six games earlier this year after surgery to repair a torn meniscus in his right knee in September. During that operation, team doctors discovered damage to the knees articular cartilage the covering that protects the bone, sources told ESPN.

The University of South Carolina product attempted to play through the pain until it became clear that the injury was significantly limiting his effectiveness. The answer was microfracture surgery, a procedure sports fans have learned to dread since its development by Dr. Richard Steadman in the late 1980s. Texans general manager Rick Smith said the team expects a full recovery for Clowney.

The human body cannot naturally regrow or repair cartilage. Without adequate coverage from cartilage, the bones in the knee become overloaded. In the past, players who suffered from degenerative conditions in their knees were forced to either play through their pain or retire. Microfracture surgery offers an alternative, by drilling small holes into the area around the knee. This allows blood and stem cells to rush to area, protecting the knee and helping to promote healing in the affected area. But the resulting cartilage is not as strong as the real thing.

Once considered experimental, it is now the most commonly performed cartilage repair procedure, with some 130,000 to 160,000 microfracture surgeries performed each year, Cole said. And its largely effective Coles team conducted a study which found 83 percent of NBA players were able to return to the court six to 12 months after undergoing the procedure.

But basketball and football make different physical demands on the human body, and every patient has a different response to the operation. While the numbers suggest Clowney will return to the gridiron at some point in the future, theres no way to guarantee that it will happen in nine months or that Clowney will be the same player when he does return, Cole said.

Even under ideal conditions, the recovery window varies wildly from patient to patient, depending on the injurys location within the knee, as well as the knees overall condition. Some athletes may return to physical activity in four to six months, while others can delay for up to a year. Some microfracture patients do not regain full strength until approximately 15 months after the procedure.

You try to make projections and offer this linear thinking, if this, then that. But the honest answer is that you cant do it. Its very hard to predict, Cole said.

And a successful surgery would not necessarily prevent Clowney from experiencing future knee discomfort. At times, patients experience incomplete pain relief or a return of knee pain after a few years each of which would hinder an athletes ability to perform at the highest level of professional football.

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Will Jadeveon Clowney Return To Form After Microfracture Surgery? Timetable, Recovery Hard To Predict, Expert Says

All you sad sack Democrats looking for a glimmer of hope in that shellacking you took on Tuesday can take comfort in this:

At least you didn't lose a single race for dogcatcher.

Of course, that's because dogcatcher is one of the few government jobs in South Carolina that is not put up for popular election.

If it was, you would have lost that, too.

Sorry, but that's about as sunny as it gets.

At some point - and this would be a good time - Democrats need to get the message that people here just don't like you. Well, 60 percent of people anyway.

You can whine all you want about how talk radio and biased TV stations have turned people against you, that the GOP has folks voting against their economic self-interests, that you really aren't the party of the devil incarnate.

But none of that matters. Folks in South Carolina aren't interested in your politics.

It is so bad that voters in Georgetown County chose a Republican who is currently under federal indictment for some shady deal involving the sale of stem cells - stem cells! - over a durn Democrat for state representative.

That's just embarrassing.

Originally posted here:
Let's face it, Democrats - you are not going to win any popularity contests in South Carolina

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NEW YORK, Oct. 13, 2014 /PRNewswire/ -- The key to Transforming Future of Diagnostic and Therapeutic Medicine

This study investigates the global stem cell market for the period 2013 to 2018. The geographic regions covered in the study are the North America, Europe and APAC, followed by a detailed Asia Pacific Region Analysis, which covers countries such as India, Australia, Thailand, Singapore, South Korea, Malaysia and Japan. The stem cell market is covered into four broad segments, namely by products, by technology and by application. The study covers various areas of interest such as regulatory policies within stem cell research, key business updates, analysis of risk factors, and strategic recommendations. Additionally, key clinical milestones, timelines of key clinical events, key companies to watch, and a strategic partnership assessment in the global stem cell market have been included.

Key Findings -The global market for stem cell was $ billion in 2013 and is expected to reach $ billion in 2018, growing at a robust CAGR of% from 2013 to 2018. -The worldwide market for adult stem cell is estimated to be at $billion in 2013 and is projected to reach $ billion by 2018. Adult stem cells constitute % of the total stem cell market. -Cord blood banking is one of the fastest growing segments of the stem cell market. The number of active cord blood banks worldwide have grown from mere in 2005 to over in 2013. -North America's total stem cell market was valued at $ billion in 2013 and is projected to increase to $ billion by 2018. -The European stem cell market was valued at $billion in 2013 and is projected to increase to $billion by 2018. -The Asia-Pacific (APAC) stem cell market was valued at $ billion in 2013 and is projected to increase to $billion by 2018. -APAC countries are progressing fast in the field of various stem cells research, including human embryonic stem cells, induced pluripotent stem cell (IPSc) and others. The major hurdle has been the regulatory environment in these countries, but that has been changing lately. Several Asian countries have modified their regulations regarding stem cell research to attract more investors. -India, Singapore and South Korea are the frontrunners and are expected to dominate the APAC stem cells market in the coming years. Favourable regulatory changes and funding support from governments have helped the commercialization of the stem cells industry. -Indian stem cell market was estimated to be $ million in 2013 and is expected to grow at a CAGR of % from 2013 to 2018. -Current penetration of stem cell banking in Singapore is % and is expected to grow at a CAGR of % in next years. -South Korea is all set to lead the stem cell research in APAC. Funding in stem cell in this country could be compared to that of US. -Stem cells obtained from adult organisms constitute the main focus of research and the ethics surrounding the use of these cells are quite undisputed. Therapies employing adult stem cells are being developed by various companies (such as ViaCell, StemSource, Osiris Therapeutics, Neural Stem, and Angioblast) and are moving fast from laboratory to the clinical application phase. -Majority of companies pursuing stem cell therapeutics are engaged in the development of adult stem cells derived from sources such as bone marrow, neural tissue, adipose tissue, menstrual blood, and placenta.

Read the full report: http://www.reportlinker.com/p02414037-summary/view-report.html

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Analysis of the Global Stem Cell Market - wistv.com ...

A new therapy is now available to help your spine repair itself. Using stem cells from your own body, this treatment, called ReNewDisc, can effectively address certain back and neck problems like degenerative disc disease.

Degenerative disc disease isnt actually a disease. Its just the term doctors use to describe a whole range of common injury or age-related degradations to the discs in your spine.

Your discs can lose fluid, reducing your flexibility, or they can tear or crack, causing them to bulge or rupture and compress nearby nerves. Both results are painful. Depending on the injured discs location, you may feel anything from mild irritation and soreness, to debilitating back or neck pain and numbness or a combination of symptoms.

If conservative care options (i.e., non-surgical methods) dont stop your pain, you may need surgery to remove a disc and replace it with an artificial one. Fusing the surrounding vertebrae is often the last-resort treatment.

Stem cell therapy, however, may help the disc to heal itself. This revolutionary treatment has the potential to reduce inflammation, thus reducing the pressure on the nerves that cause the pain or numbness. Watch this short video about stem cell therapy at the Southeastern Spine Institute:

Stem cell therapy may be appropriate for treating degenerative disc disease in the cervical and lumbar discs. It is not able to treat the following medical conditions:

While not everyone with back or neck pain in Charleston, SC, is a candidate for stem cell therapy, the board certified physicians at Southeastern Spine can examine you during a consultation in our office to determine if you are suitable for the procedure.

Link:
Stem Cell Therapy for Spine Injuries at The Southeastern ...

Scientists have developed a gel that helps brains recover from traumatic injuries. It has the potential to treat head injuries suffered in combat, car accidents, falls, or gunshot wounds. Developed by Dr. Ning Zhang at Clemson University in South Carolina, the gel is injected in liquid form at the site of injury and stimulates the growth of stem cells there.

Brain injuries are particularly hard to repair, since injured tissues swell up and can cause additional damage to the cells. So far, treatments have tried to limit this secondary damage by lowering the temperature or relieving the pressure at the site of injury. However, these techniques are often not very effective.

More recently, scientists have considered transplanting donor brain cells into the wound to repair damaged tissue. This method has so far had limited results when treating brain injuries. The donor cells often fail to grow or stimulate repair at the injury site, possibly because of the inflammation and scarring present there. The injury site also typically has very limited blood supply and connective tissue, which might prevent donor cells from getting the nutrients they require.

Dr. Zhang's gel, however, can be loaded with different chemicals to stimulate various biological processes at the site of injury. In previous research done on rats, she was able to use the gel to help re-establish full blood supply at the site of brain injury. This could help create a better environment for donor cells.

In a follow-up study, Dr. Zhang loaded the gel with immature stem cells, as well as the chemicals they needed to develop into full-fledged adult brain cells. When rats with severe brain injuries were treated with this mixture for eight weeks, they showed signs of significant recovery.

The new gel could treat patients at varying stages following injury, and is expected to be ready for testing in humans in about three years.

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A Squirt of Stem Cell Gel Heals Brain Injuries | Popular ...

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Greenville SC Resources - Stem Cells: Get Facts on Uses ...

*Provider Directory Terms of Use:

The WebMD 'Provider Directory' is provided by WebMD for use by the general public as a quick reference of information about Providers. The Provider Directory is not intended as a tool for verifying the credentials, qualifications, or abilities of any Provider contained therein. Inclusion in the Provider Directory does not imply recommendation or endorsement nor does omission in the Provider Directory imply WebMD disapproval.

You are prohibited from using, downloading, republishing, selling, duplicating, or "scraping" for commercial or any other purpose whatsoever, the Provider Directory or any of the data listings or other information contained therein, in whole or in part, in any medium whatsoever.

The Provider Directory is provided on an "AS-IS" basis. WebMD disclaims all warranties, either express or implied, including but not limited to the implied warranties of merchantability and fitness for particular purpose. Without limiting the foregoing, WebMD does not warrant or represent that the Provider Directory or any part thereof is accurate or complete. You assume full responsibility for the communications with any Provider you contact through the Provider Directory. WebMD shall in no event be liable to you or to anyone for any decision made or action taken by you in the reliance on information provided in the Provider Directory.

The use of WebMD Provider Directory by any entity or individual to verify the credentials of Providers is prohibited. The database of Provider information which drives WebMD Provider Directory does not contain sufficient information with which to verify Provider credentials under the standards of the Joint Commission on Accreditation of Healthcare Organizations (JCAHO), National Committee for Quality Assurance (NCQA) of the Utilization Review Accreditation Committee (URAC).

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Charleston SC Resources - Stem Cells: Get Facts on Uses ...

Qian Wang at work among plants that host some of the building blocks of his nanomolecular scaffolds.

By Steven Powell, spowell2@mailbox.sc.edu, 803-777-1923

If you break a bone, you know you'll end up in a cast for weeks. But what if the time it took to heal a break could be cut in half? Or cut to just a tenth of the time it takes now? Qian Wang, a chemistry professor at the University of South Carolina, has made tantalizing progress toward that goal.

Wang, Andrew Lee and co-workers just reported in Molecular Pharmaceutics that surfaces coated with bionanoparticles could greatly accelerate the early phases of bone growth. Their coatings, based in part on genetically modified Tobacco mosaic virus, reduced the amount of time it took to convert stem cells into bone nodules from two weeks to just two days.

The key to hastening bone healing or growth is to coax a perfectly natural process to pick up the pace.

"If you break a rib, or a finger, the healing is automatic," said Wang. "You need to get the bones aligned to be sure it works as well as possible, but then nature takes over."

Healing is indeed very natural. The human body continuously generates and circulates cells that are undifferentiated; that is, they can be converted into the components of a range of tissues, such as skin or muscle or bone, depending on what the body needs.

The conversion of these cells called stem cells is set into motion by external cues. In bone healing, the body senses the break at the cellular level and begins converting stem cells into new bone cells at the location of the break, bonding the fracture back into a single unit. The process is very slow, which is helpful in allowing a fracture to be properly set, but after that point the wait is at least an inconvenience, and in some cases highly detrimental.

"With a broken femur, a leg, you can be really incapacitated for a long time," said Wang. "In cases like that, they sometimes inject a protein-based drug, BMP-2, which is very effective in speeding up the healing process. Unfortunately, it's very expensive and can also have some side effects."

In a search for alternatives four years ago, Wang and colleagues uncovered some unexpected accelerants of bone growth: plant viruses. They originally meant for these viruses, which are harmless to humans, to work as controls. They coated glass surfaces with uniform coverings of the Turnip yellow mosaic virus and Tobacco mosaic virus, originally intending to use them as starting points for examining other potential variations.

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University of South Carolina - News