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Category Archives: Regenerative Medicine

ISSCA Announces the Program Agenda of Regenerative Medicine World Congress 2022 – Digital Journal

Posted: July 27, 2022 at 2:17 am

The International Society for Stem Cell Application (ISSCA) is hosting the most anticipated regenerative medicine event of he year Regenerative Medicine World Congress 2022. The congress will take place at the Radisson Blu Hotel Istanbul Sisli, Turkey, on September 23. 24. and 25.

The congress features theoretical lectures on the first two days. Physicians and scientists from around the world will present evidence-based research; demonstrate updates on technologies. products, and equipment; share their extensive experience in clinical applications of regenerative medicine and cellular therapies. 30 presentations focusing on stem cell research and regenerative medicine will be given by clinicians and researchers in different specialties. Featured topics include:

Mesenchymal stem cells (MSC).- Exosomes.- Plastic and reconstructive surgery.- Clinical trials.- Nerve injury treatment.- Applications in ophthalmology and cardiology.- Immunotherapy.

The congress will be the ultimate gathering and a showcase of the most cutting-edge research in regenerative medicine. Congress participants will be able to network with like-minded medical professionals from different parts of the world and become part of a growing community leading the future of medicine.

With theAll-Access package, congress participants will have access to thehands-on practice certification portionon the third day. The live practical portion has only 20 limited seats available.

ISSCA-certified instructors, Dr. Maritza Novas (Director of Research and Development at Global Stem Cells Group. USA) and Dr. Melihcan Sezgic (Plastic. Reconstructive and Aesthetic Surgeon. Regenerative Medicine Specialist. Turkey), will lead one-on-one training sessions at the ReGen iC Clinic. This is a great opportunity to gain intensive hands-on experience in the aesthetic and clinical applications of stem cell therapy. The following training modules are included:

Cellular Products

1. Mononuclear layer umbilical cord blood

2. Exosomes: Characterization, examination of growth factors and cytokines

3. Amniotic fluid and its action as a natural anti-inflammatory

Production, Manufacturing, and Quality Control

1. Eligibility and selection of donors

2. Collection and management of samples

3. Processing and laboratory standards

4. Testing and validation of quality control

1. Clinical framework for therapeutic applications

2. Protocol details and supporting scientific literature

3. Product storage and preparation

4. Selection of patients

5. Results and expectations of patients

Application of the Protocol in Live Patients

1. Demonstration of product preparation and injection

About ISSCA:

The ISSCA is a multidisciplinary community of physicians and scientists with a mission to advance the science, technology, and practice of Regenerative Medicine to treat disease and lessen human suffering. Its members are leaders in setting standards and promoting excellence in regenerative medicine, related education, certification, research, and publications.

The Regenerative Medicine World Congress 2022 will be one of the most celebrated events of the year. where we share the ISSCA values in Integrity, Interdisciplinary, and Innovation. The ISSCA invites physicians and healthcare professionals devoted to regenerative medicine to expand their network, access world-class speakers, and update themselves with the latest technologies, products, and equipment.

For more information. please fill out the form tocontact us.

Media ContactCompany Name: ISSCAContact Person: Benito NovasEmail: Send EmailPhone: +1 (305) 560-5337Address:Datran Center 9100 S Dadeland Boulevard, Suite 1500 City: MiamiState: Fl. 33156Country: United StatesWebsite: https://www.issca.us/

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ISSCA Announces the Program Agenda of Regenerative Medicine World Congress 2022 - Digital Journal

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Cell Therapy Market to Generate $35.95 billion, Regenerative Therapy and 3D Printing to Remain in Limelight – GlobeNewswire

Posted: July 27, 2022 at 2:17 am

Westford, USA, July 26, 2022 (GLOBE NEWSWIRE) -- The cell therapy market is set to grow at an exponential CAGR and will shape patient care in many sectors, and its growth may be reduced only by the inability to control costs. In the last few years, the market has gained an immense popularity for cell therapy across numerous for applications such as cosmetics and transplant. In line with this, the global cell therapy market witnessed a considerable rise in the number of clinical trials undertaken globally. As per SkyQuest analysis, during 2007-2016, more than 251 clinical trials were registered. Wherein, the year 2007, registered the only 3 trials and it went to increase to 116 in 2016. In addition, over 73% of these clinical trials were found to be distributed under non-commercial applications and 26.40 were meant for commercial purpose.

Cell therapy is a rapidly growing field with great potential for treating many diseases including cancer, diabetes, and neurodegenerative diseases. Apart from this, this treatment option has the potential to restore health and improve the quality of life for patients.

In the report published by SkyQuest on Cell Therapy Market, we examine the future of the cell therapy market and related trends innovations that are supporting its growth.

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Cell Therapy is Ray of Hope for Cancer Patients

Cell therapy is providing hope and healing to cancer patients. This innovative form of treatment is based on reprogramming the cells in the body to fight tumors. Researchers are constantly discovering new ways to target and treat cancer with cell therapy, and it is expected to play an important role in the future of cancer care.

While cell therapy is still relatively new, it has already shown great promise in the treatment of cancer.

Some of the most well-known cell therapies include cancer immunotherapy and adoptive T-cell therapy. Cancer immunotherapy uses the patient's own immune system to fight their cancer. adoptive T-cell therapy works by using T-cells from a donor to help fight the cancer.

The report has explored several active players in the market and how they are performing. One provider that is doing well in the cell therapy industry is OncoCyte Corporation. The company has developed several new therapies that are effective in treating various forms of cancer. OncoCyte currently offers treatments for cervical, lung, and pancreatic cancer. These treatments are reasonably priced, making them a valuable option for patients seeking treatment for their cancer.

Stem Cells is Becoming More Common as a Therapeutic Option

As per SkyQuest Technology, global stem cell therapy market is estimated to grow from $6.87 billion in 2016 to $15.63 billion by 2025. This growth is being driven by the increasing prevalence of disease, rising demand for regenerative medicine, and growing investment in the development of novel cell therapies.

Stem cells are becoming more common as a therapeutic option because they have the ability to become any type of cell in the body. This means that they can be used to treat a wide variety of diseases and injuries. For example, stem cells have been used to successfully treat leukemia and lymphoma. They are also being studied for their potential to treat other types of cancer, Alzheimer's disease, Parkinson's disease, spinal cord injuries, and diabetes.

One of the main drivers of the cell therapy market is the increasing prevalence of diseases such as cancer and neurodegenerative diseases. Cancer is currently the leading cause of death worldwide and killing over 10 million people around the globe every year, and is expected to account for more than half of all deaths by 2030. Cell therapy products that are approved for use in cancer treatment include treatments for leukemia, lung cancer, breast cancer, and several others.

Neurodegenerative diseases are also on the rise, as they are responsible for a large number of disabilities and deaths. Every year, it affects around 2% of the global populated aged 65 and above. Cell therapy products that are approved for use in neurodegenerative disease treatment include treatments for Alzheimers disease, Parkinsons disease, and multiple sclerosis.

Additionally, cell therapy products that are used to regenerate tissue are also driving growth in cell therapy market. These products are not as mature as some of the others in the market, but have exhibited steady growth, and have a chance to further expand. The functionality of cell therapy products extends beyond improving the usability of existing treatment options for cancer, neurodegenerative disease, and other disorders. Employing more effective therapies can offer substantial benefits to those who receive them by reducing pain and improving quality of life.

Despite the promising potential of stem cell therapy, there are still many challenges that need to be addressed before it can become a mainstream treatment option. One of the main challenges is developing an efficient and safe method for delivering stem cells to the target site in the body.

SkyQuest has identified opportunities in stem cell therapy market and how it competing with other available treatment options. The report provider in-depth market analysis, potential opportunities, revenue pockets, company profiles, market dynamics, and current trends.

Browse summary of the report and Complete Table of Contents (ToC):

https://skyquestt.com/report/cell-therapy-market

Regenerative Medicine to Top the Cell Therapy Market

The field of regenerative medicine is one of the most promising and rapidly growing areas in the biomedical sciences. Regenerative medicine focuses on the replacement, repair or regeneration of cells, tissues or organs to restore function in patients with conditions such as heart disease, diabetes and Alzheimers disease. Global regenerative cell therapy market is poised to attain a value of $6.9 billion by 2025.

In recent years, cell therapy market has gained immense popularity and emerged as a leading approach in regenerative medicine for treating a wide range of diseases and injuries, including heart disease, stroke, diabetes, Parkinsons disease and spinal cord injury. As per latest study by SkyQuest, most of the companies offering regenerative cell therapy are located in North America. To be precise, North America is housing around 50% of the global companies active in regenerative cell therapy market. On the other hand, Asia Pacific (27.20%) and Europe (19.30%) are holding second and third largest market share in terms of presence of companies.

The regenerative cell therapy market is expanding at a rapid pace, with investors realizing the potential for this field. In 2021, as per SkyQuest analysis, the market attracted an investment of over $23 billion across gene & gene modified cell therapy, cell therapy, and tissue engineering. However, cell therapy remained the major interest of investors as the segment attracted an investment of more than $12 billion, which is followed by gene and gene modified therapy in 2021. Other major companies include Osiris Therapeutics Inc., and Kite Pharma Ltd. The cell therapy witnessed a significant surge in the investment since 2016, which witnessed an investment of over 1.8 billion, but it went on to grow to $12 billion in 2021. This indicates the how cell therapy market is expanding as more area of application are being explored.

The potential benefits of regenerative cell therapy are vast. The therapies can help treat conditions such as cancer, ALS, diabetes, and heart disease. They can also restore damaged tissues and organs. In addition to treating human patients, Regenerative Medicine Labs is also working on treatments for animals.

Investors are bullish on the potential of this field, with several firms announcing large rounds of funding in recent months. This investment will help drive the development of these therapies further and provide relief to patients worldwide.

SkyQuest has published a new report on cell therapy market that primarily focuses on how the demand for regenerative and stem cell therapy is growing. It dives deep into understanding potential investment pockets, market regulation, analysis of historical investment by sub-segments, opportunities, and market dynamics.

3D Printing is Gaining All the Attention for Custom-Made Implants and Scaffolds for Tissue Regeneration

This little-known technology is capable of engineering 3D scaffolds to allow stem and progenitor cells to proliferate. This has the potential of opening up new possibilities in regenerative cell therapy market such as it can improve the quality of implants and scaffolds. Implant materials are often degraded over time and may need to be replaced. However, with a 3D printer you can create implants using customized templates that are specific to the individual patients needs. This means that implants created using a 3D printer can be more durable and longer lasting than those made using traditional methods.

One of the biggest challenges in regenerative cell therapy market is a lack of viable cells that can be used to repair damaged tissue. Wherein, 3D Printed scaffolds could play a role in solving this problem. A 3D printed scaffold is a type of therapeutic device that is used to promote tissue growth. The scaffold is made from layers of biological materials that have been bonded together using a printing process.

The application of 3D printing to tissue regeneration has many benefits. The first advantage is the flexibility of the scaffold. This allows it to conform to the contours of the tissue that it is replacing. Another major benefit of 3D printed scaffolds is their ability to generate multiple copies of the scaffold. This allows for more rapid healing and more accurate reconstruction of the damaged tissue.

Despite these advantages, there are some potential problems with using 3D printed scaffolds in regenerative cell therapy market. One issue is that they can be difficult to print correctly. This can lead to defects in the scaffold that may interfere with its function.

Overall, 3D printed scaffolds have many potential benefits for regenerative medicine. However, there are still some limitations to be addressed before they can be widely adopted by researchers. SkyQuest technology has covered over 100 clinical trials and their potential application in cell therapy market. This would help the companies in understanding current growth opportunities and development in the market.

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Increasing Interest in using Natural or off-the-Shelf Cells for Cell Therapy Rather than Genetically Modified

The use of natural or off-the-shelf cells for cell therapy is an area of increasing interest. The main advantage of using these cells is that they are not genetically modified, which avoids the potential risks associated with genetic modification. Additionally, off-the-shelf cells are readily available and do not require the time and expense of creating a custom cell line for each patient.

There are several types of off-the-shelf cells that have been investigated in the cell therapy market, including mesenchymal stem cells (MSCs), induced pluripotent stem cells (iPSCs), and embryonic stem cells (ESCs). MSCs can be easily isolated from adult tissue and expanded in culture, making them a readily available source of therapeutic cells. iPSCs can be generated from a patients own skin or blood Cells, meaning they would be immune-compatible with the recipient and would not require immune suppression. ESCs are derived from early-stage embryos and have the ability to differentiate into any cell type in the body; however, their use is limited by ethical concerns.

Prominent Players in Cell Therapy Market

Related Reports in SkyQuests Library:

Global Stem Cell Market

Global Flow Cytometry Market

Global Biomaterials Market

Global Bioinformatics Market

Global Synthetic Biology Market

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Cell Therapy Market to Generate $35.95 billion, Regenerative Therapy and 3D Printing to Remain in Limelight - GlobeNewswire

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Regenerative Medicine Market Size, Scope, Growth Opportunities, Trends by Manufacturers And Forecast to 2029 This Is Ardee – This Is Ardee

Posted: July 27, 2022 at 2:17 am

New Jersey, United States This Regenerative Medicine Market research works as the best evaluation tool to track the progress of the industry and keep an eye on the competitors growth strategies. It further helps to keep you ahead of your business competitors. This report depicts a few potential problems and gives solutions to them by doing comprehensive research on the market scenario. Valuable information is provided here about a particular market segment according to product type, application, region type, and end user. By referring to this comprehensive Regenerative Medicine market analysis report, it becomes possible for organizations to monitor the efficiency of sales, determine the quality of services offered by competitors, estimate the competition level in the market and understand the communication channels followed by competitors in the market.

This Regenerative Medicine Market research report covers career outlooks, regional marketplaces, and an overview of the expectations of a number of end-use sectors. With the help of relevant market data, key organizations are able to obtain a competitive benefit over the competitors in the market and attain the best results for business growth. Furthermore, this Regenerative Medicine market analysis report emphasizes doing a comparison between several various geographical markets in key regions such as North America, Europe, Middle East, Africa, Latin America, and Asia Pacific. It aims at covering complex structures to classifications to an easy-to-follow overview of different business sectors.

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Key Players Mentioned in the Regenerative Medicine Market Research Report:

Organogenesis Inc., Osiris Therapeutics Vericel Corporation, Stryker Corporation and NuVasive, Inc.

A massive amount of information presented in this Regenerative Medicine Market report helps business players to make beneficial decisions. Some of the major key aspects covered in this market analysis are key performance indicators, customer acquisition, and manufacturers list. Performance results of the marketing plan are also covered in this market analysis report. This market study report enables to bring the improvements required in the business. It further talks about how COVID-19 caused huge trauma in several major sectors. Key marketing channels, market growth opportunities, core marketing strategy, and current scope of the business are some of the major factors discussed in this report. It further briefs on the current position of the market. It depicts the effect of metrics on market trends, revenue, and leads.

Regenerative MedicineMarket Segmentation:

Regenerative Medicine Market, By Product

Cell-Based Products Acellular Products

Regenerative Medicine Market, By Therapy

Tissue Engineering Immunotherapy Gene Therapy Cell Therapy Others

Regenerative Medicine Market, By Application

Central Nervous System Diseases Oncology Diabetes Orthopedic & Musculoskeletal Disorders Dermatology Cardiology Others

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For Prepare TOC Our Analyst deep Researched the Following Things:

Report Overview:It includes major players of the Regenerative Medicine market covered in the research study, research scope, market segments by type, market segments by application, years considered for the research study, and objectives of the report.

Global Growth Trends:This section focuses on industry trends where market drivers and top market trends are shed light upon. It also provides growth rates of key producers operating in the Regenerative Medicine market. Furthermore, it offers production and capacity analysis where marketing pricing trends, capacity, production, and production value of the Regenerative Medicine market are discussed.

Market Share by Manufacturers:Here, the report provides details about revenue by manufacturers, production and capacity by manufacturers, price by manufacturers, expansion plans, mergers and acquisitions, and products, market entry dates, distribution, and market areas of key manufacturers.

Market Size by Type:This section concentrates on product type segments where production value market share, price, and production market share by product type are discussed.

Market Size by Application:Besides an overview of the Regenerative Medicine market by application, it gives a study on the consumption in the Regenerative Medicine market by application.

Production by Region:Here, the production value growth rate, production growth rate, import and export, and key players of each regional market are provided.

Consumption by Region:This section provides information on the consumption in each regional market studied in the report. The consumption is discussed on the basis of country, application, and product type.

Company Profiles:Almost all leading players of the Regenerative Medicine market are profiled in this section. The analysts have provided information about their recent developments in the Regenerative Medicine market, products, revenue, production, business, and company.

Market Forecast by Production:The production and production value forecasts included in this section are for the Regenerative Medicine market as well as for key regional markets.

Market Forecast by Consumption:The consumption and consumption value forecasts included in this section are for the Regenerative Medicine market as well as for key regional markets.

Value Chain and Sales Analysis:It deeply analyzes customers, distributors, sales channels, and value chain of the Regenerative Medicine market.

Key Findings:This section gives a quick look at the important findings of the research study.

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Regenerative Medicine Market Size, Scope, Growth Opportunities, Trends by Manufacturers And Forecast to 2029 This Is Ardee - This Is Ardee

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Low Endotoxin Gelatin Market Expected to Witness a Sustainable Growth by 2027 – BioSpace

Posted: July 27, 2022 at 2:17 am

Wilmington, Delaware, United States, Transparency Market Research Inc.: Gelatin, a protein product derived from collagen, plays an important role in joint health and brain function. It also improves appearance of hair and skin. It is formed by partial hydrolysis of collagen.

It is used as an excipient in the pharmaceutical industry. Other applications areas of gelatin include hemostatic applications for bleeding control, drug delivery, and regenerative applications.

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Endotoxins are immunogenic molecules that are found in outer membrane of gram-negative bacteria. They are heat resistant and initiate immune response when exposed to immune system. This results in tissue inflammation, thereby increasing sensitivity to allergens.

The effect of endotoxin is mediated by the inflammasome and a TLR receptor cytokines

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Key Drivers & Restraints of Global Low Endotoxin Gelatin Market

Increase in adoption of regenerative medicine, new medical grade gelatin range launched by prominent market players, and expanding applications of low grade gelatin in medicine primarily drive the global low endotoxin gelatin market

For instance, in May 2018, Rousselot, the manufacturer of gelatin and collagen peptides, launched X-Pure, a medical grade gelatin range for in-body applications. The product has applications in hemostatic medical device, parenteral formulations, and regenerative medicine.

A company named Nitta Gelatin, NA Inc. manufacturers pharmaceuticals and food. beMatrix, is a low endotoxin gelatin, having applications in scientific research and medical devices.

Rise in efforts by prominent market players in supplying new product-line of materials for biomedical use is expected to boost the low endotoxin gelatin market

However, stringent regulatory requirements governing the use of low endotoxin gelatin in medical applications is likely to restrain the growth of the market during the forecast period

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Source Segment to Account for Major Share of Global Market

Based on source, the global low endotoxin gelatin market can be classified into porcine skin and bovine skin

The porcine skin segment is anticipated to dominate the global market during the forecast period, owing to an increase in number of new products from porcine skin based low endotoxin grade

Regenerative Medicine Segment to Offer Significant Opportunities

In terms of application, the global low endotoxin gelatin market can be segmented into hemostatic applications, drug delivery & parenteral applications, biomedical applications, regenerative medicine applications, and others. The regenerative medicine applications segment is further categorized into implantable membranes, 3D bioprinting, stem cell & organoid culturing, and others.

The regenerative medicine applications segment is expected to gain significant share of share the global low endotoxin gelatin market by 2027. Increase in demand for low endotoxin gelatin in regenerative medicines is likely to drive the segment. Gelatin-based delivery systems used for targeted release for biomolecules are expected to gain importance. Reduction in endotoxin levels in gelatin is primarily important in regenerative medicine which has led to an increase in research & development activities for developing wide range of low endotoxin gelatin.

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North America to Dominate Global Low Endotoxin Gelatin Market

In terms of region, the global low endotoxin gelatin market can be segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America is projected to dominate the global low endotoxin gelatin market during the forecast period.

Recent product launch in the U.S., presence of prominent market players, extensive growth of regenerative medicine, and rise in demand for drug delivery technologies are various factors projected to drive the market in North America

Key Players Operating in Global Low Endotoxin Gelatin Market

The global low endotoxin gelatin market is highly fragmented, with a large number of domestic players accounting for a major market share. Key players operating in the global low endotoxin gelatin market are:

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Low Endotoxin Gelatin Market Expected to Witness a Sustainable Growth by 2027 - BioSpace

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Robotics And AI As Accelerators Of Advances In Regenerative Medicine – Nation World News

Posted: July 27, 2022 at 2:17 am

Technology in the service of health. Once again, technological progress has resulted in obvious benefits to humans; In this case, in health matters. a group of scientists has developed a robotic system based on artificial intelligence that automatically determines what are the optimal conditions for the replacement layers of the retina to grow Required in various treatments aimed at restoring vision.

During the last experiment, The system underwent a trial and error process covering a total of 200 million possible configurations and managed to dramatically improve cell culture viability Regenerative medicine is essential to the therapy. A feat that exemplifies how the automated design and execution of scientific experiments can increase the efficiency and speed of research in countless fields such as biology.

Traditionally, research in regenerative medicine has required a number of experiments that require a great deal of time and work. especially, Creating specific tissues from stem cells a process called induced cell differentiation takes months of work, and the degree of success depends on a wide range of variables., Finding the optimal type, dosage and timing of reagents as well as optimal physical variables, such as cell transfer time or temperature, is difficult and requires an enormous amount of testing.

Thus, to make this process more efficient and practical, a research team led by Genki Kanda from the RIKEN Institute in Japan set out to Develop an autonomous experimental system that can determine optimal conditions and grow functional retinal pigment layers from stem cells, For this Retinal pigment epithelial cells were selected Because the degeneration of these cells is a common aging-related disorder that makes people unable to see. More importantly, transplanted retinal pigment epithelial layers have already shown some clinical success.

For autonomous experiments to be successful, the robot must perform the same series of precise movements and manipulations over and over again; And artificial intelligence, for its part, should be able to evaluate the results and prepare for the next experiment. The new system accomplishes these goals, thanks to a general-purpose humanoid robot called Maholo, which is capable of conducting high-precision biological experiments. Maholo to a. is controlled by software Artificial Intelligence that uses a newly designed optimization algorithm To determine which parameters should be changed, and how they should be changed, to improve the differentiation efficiency in the next round of experiments.

In what would have taken human researchers more than two and a half years, robotic systems with artificial intelligence took only 185 days. translate the Go from initial efficiency to 90% in resolution rate of 50% for experiment and improvement work Created by Robot.

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Robotics And AI As Accelerators Of Advances In Regenerative Medicine - Nation World News

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Dynamic changes in the niche and transcription trigger early murine and human pluripotent stem cell-derived liver organogenesis – Newswise

Posted: July 27, 2022 at 2:17 am

Abstract: Organoids bearing human stem cell-derived progenitors enable basic and applied investigation of organogenesis in a wide range of epithelial tissues. During liver organogenesis (LO), E9.5 collectively migrating hepatoblasts (MHs) arise from the E9.0 liver diverticulum (LD) and directly penetrate the surrounding mesoderm (MES) tissue, forming cell strands that link migration, differentiation, and growth. Currently, human pluripotent stem cell (hPSC) organoid protocols model the E10.5 liver bud and forward differentiation, but not the LD or the LD-derived MHs, in spite of their significance. In fact, the transcriptome underlying MHs, the niche that drives their migration, and methods to induce them from hPSC remain key questions. We performed bioinformatics analysis of single cell RNA-seq data, in vivo transplantation, and in vitro hPSC differentiation with organoid formation, microscopy, gene and protein expression, small molecule inhibitor screening of growth, and organoid culture in bioengineered devices to assess tissue tension. Our in depth bioinformatic analysis of early murine LO demonstrates pathway up-regulation of an unexpected wide array of soluble signaling factors, as well as cell cycle, chromatin modification, and metabolic reprogramming, in addition to a widespread cell stress-response. These findings led us hypothesize that the LD and MES tissue form a tissue complex (LD-MESC) that drives MH induction. Using this LD-MESC concept, we designed an in vivo transplant system, as well as a three-step in vitro protocol for inducing hPSC-derived MHs, both of which recapitulate liver growth, morphogenesis, differentiation. We show that Hippo signaling pathway, in agreement with murine MH data, mediates migration and growth of hPSC-MH in vitro. These data substantiate the LD-MESC model developed here, and directly address key challenges facing liver regenerative medicine. Our bioinformatics, in vitro, and in vivo data all support the concept that the LD-MESC initiates LO. This concept can be used to change protocols to emphasize linking of migration, growth, with differentiation. Modeling epithelial collective migration for LO bolsters not only organogenesis studies of alternate endodermal organs, but also in vivo transplantation efforts, and facilitates employing migrating organoids to therapeutically target human tumor migration/metastasis.

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Dynamic changes in the niche and transcription trigger early murine and human pluripotent stem cell-derived liver organogenesis - Newswise

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CSafe Global Continues Investment in Cell and Gene Therapy Solutions with Addition of New Portfolio President – PR Newswire

Posted: July 27, 2022 at 2:17 am

Ms. DuRossbrings more than 25 years' experience to her new position. Prior to joining CSafe, she was the co-founder and CEO of Vineti, an enterprise software platform used to digitize chain of identity and chain of custody requirements for CGT products. Earlier in her career, DuRoss held several prestigious positions including, Chief Business Officer at Navigenics, Chief of Staff for the California Institute for Regenerative Medicine (CIRM), and Co-Founder, Co-Author, and Executive Director of California's $3B stem cell research ballot initiative.

"We are delighted to have Amy leading our CGT team. Her diverse experience in both corporate development, patient advocacy and entrepreneurship is exactly the right mix to drive innovation and superior solutions in this deeply complex supply chain," said CSafeCEO, Patrick Schafer. "We expect to see significant strides forward in this portfolio under Amy's strategic guidance."

"I'm honored to have the opportunity to collaborate with the world-class team at CSafe Global in bringing a new standard of high-quality, high-value supply chain transport to the most exciting innovation area in personalized medicine, cell and gene therapies," Ms. DuRoss said, "CSafe Global's outstanding worldwide service network and proven expertise in robust and actionable analytics to drive supply chain efficiencies will hasten the industrialization of an emergent market that offers critical hope for an increasing number of patients in need."

Ms. DuRossearned her bachelor'sand two master'sdegrees, including her MBA, from Stanford University. She serves on the boards of Biolife Solutions (BLFS), MJH, Americans for Cures, and the ARM Foundation and is a member of the Aspen Institute Global Network.

Media Contact:Lori ConawayGlobal Marketing Communications+1 405.633.2344[emailprotected]

About CSafe Global

CSafe Global provides end-to-end thermal shipping solutions to the pharmaceutical and life science industries worldwide. An industry innovator, CSafe provides AI-enabled lease forecasting to ensure active container availability and real-time shipment visibility for customers to monitor shipments and intervene to preserve a payload when needed. CSafe offers industry-leading maintenance and reuse programs for active and passive containers providing superior product performance and alignment with customer sustainability objectives. With a presence in 150 countries, 24/7 support and 100% container availability, CSafe is well-positioned to be the partner of choice in the cold chain. csafeglobal.com

SOURCE CSafe Global

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CSafe Global Continues Investment in Cell and Gene Therapy Solutions with Addition of New Portfolio President - PR Newswire

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South Texans can participate in massive, national health program to change the future of healthcare – Yahoo Finance

Posted: July 27, 2022 at 2:17 am

The National Institutes of Healths All of Us Research Program aims to recruit 1 million participants to advance biomedical research to benefit all

SAN ANTONIO, July 25, 2022 (GLOBE NEWSWIRE) -- South Texas Blood & Tissue has partnered with the National Institutes of Healths All of Us Research Program, to recruit and engage participants in one of the nations largest and most diverse health information databases.

All of Us aims to enroll at least 1 million participants who reflect the rich diversity of the U.S. Participants can choose to share information about their health history, their environment and they can contribute a blood or saliva sample. This information will help researchers learn how biology, lifestyle and our environment affect our health.

One of the biggest goals of this program is to increase diversity in medical research. Many populations have been left out of research in the past, which means less is known about the health of those groups.

South Texans can join the program by visiting JoinAllofUs.org/SouthTexasBlood. After completing an online portion (including study consents and health history surveys), participants may be asked to visit South Texas Blood & Tissue in San Antonio to have physical measurements taken and give blood and urine samples for the program.

Biological information, health surveys and physical measurements all can help researchers in the new field of precision medicine, which aims to create tailored treatments that are not one-size-fits-all. With this resource, researchers will be able to conduct thousands of studies on health and disease.

All information collected for All of Us will be stored on protected computers, and the NIH will remove participants names and other direct identifiers like Social Security numbers.

Participants may be compensated for their time and travel with a $25 gift card after giving their samples at South Texas Blood & Tissue. Through participating in the program, participants also can receive specific information about their DNA that could help them learn about their unique traits and genetic ancestry, if they want to receive genetic health-related information.

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Anyone 18 years or older living in the United States may participate in this program, regardless of health condition or prior blood donation eligibility.

Joining All of Us is another way for generous donors to improve the health of communities and future generations.

To learn more about All of Us, please call 210-731-5589 or email Research@SouthTexasBlood.org.

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About South Texas Blood & Tissue: South Texas Blood & Tissue (STB&T) is a nonprofit community blood center that provides blood, plasma, platelets, and other blood components to 100 hospitals in 48 South Texas counties. It is the largest blood supplier in our region. In addition, STB&T supports the development of advanced therapies, including those derived from donated human cells and tissues used in research and in new therapies and cures for cancers and degenerative diseases. Through the generous life-legacy gifts of human tissue, STB&T also supports development of tissue allografts for patients in need of reconstructive surgery, repair, or tissue regeneration. STB&T has a 47-year history serving the South Texas community and is part of the BioBridge Global family of nonprofit organizations, which offers services in regenerative medicine and research including blood banking and resource management; cellular therapy; umbilical cord blood collection and storage; donated human tissue recovery and distribution for transplant; and testing of blood and plasma products to help patients in the United States and worldwide. STB&T has seven donor centers in South Texas and conducts hundreds of mobile blood drives each year. STB&T is online at SouthTexasBlood.org.

About BioBridge Global: BioBridge Global (BBG) is a San Antonio-based 501(c)(3) nonprofit regenerative medicine enterprise that offers diverse services through its subsidiaries South Texas Blood & Tissue, QualTex Laboratories, GenCure and The Blood & Tissue Center Foundation. BBG provides products and services in blood resource management, cellular therapy, donated umbilical cord blood and human tissue, as well as testing of blood, plasma and tissue products for clients in the United States and worldwide. BBG is committed to saving and enhancing lives through the healing power of human cells and tissue. It enables advances in the field of regenerative medicine by providing access to human cells and tissue, testing services and biomanufacturing and clinical trials support. Learn more at BioBridgeGlobal.org.

All of Us is a registered service mark of the U.S. Department of Health & Human Services (HHS).

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South Texans can participate in massive, national health program to change the future of healthcare - Yahoo Finance

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Replay Launches with $55M In Seed Funding To Author Genomic Medicine – BioSpace

Posted: July 27, 2022 at 2:17 am

Genome writing company Replay haslaunchedoperations with $55 million in seed financing, mainly from OMX Ventures and KKR.

Replay features next-generation genomic medicine technologies in its portfolio to address the needs of diseases that have large unmet needs. It also aims to create solutions to increase payload capacity and off-the-shelf cell therapies that will improve production volume, speed and consistency, reduce costs and expand opportunities for genome engineering.

Some of the genomic medicine platforms that Replay is working onincludeuCell, a universal, renewable, genomically rewritten iPSC-derived cell source for regenerative medicine and cell therapy; synHSV, a high-payload-capacity HSV vector that can deliver as much as 30 times the AAV payload; and DropSynth, a genome writing platform that enables the low-cost and rapid synthesis of big DNA and libraries of synthetic genes. Its fourth platform, LASR, offers an inference algorithm that can rewrite proteins to achieve optimal functionality.

Replay takes pride in its unique corporate structure, which keeps the therapeutic product development and technology development units separate. The company has set up four synHSV companies to bring key DNA treatments to monogenic disorders affecting the brain, muscle, eye and skin.

"Genomic medicine has the potential to transform the future of clinical therapeutics. Over my three decades of experience working in clinical medicine, academia, and the biopharmaceutical industry, it has become clear that we require a more robust and comprehensive toolkit of molecular genetic platform technologies to solve biology's most complex problems and realize its full therapeutic potential," Adrian Woolfson, B.M., B.Ch., Ph.D., the executive chairman, president and co-founder of Replay, commented in a statement.

Replay was co-founded by Woolfson, Lachlan MacKinnon, and Ron Weiss, Ph.D. MacKinnon is a founding team member at Oxford Science Enterprises and a founding investor in ONI, OMass Therapeutics and Base Genomics, while Weiss is a professor of biological engineering at the Massachusetts Institute of Technology. Before Replay, Woolfson was the executive vice president, head of research and development at Sangamo Therapeutics, and chief medical officer at Nouscom.

"Replay's mission is to create a world-leading company that develops and owns the tools to reprogram biology by writing and delivering big DNA; we believe these capabilities will unlock the largest untapped opportunity in medicine. Replay has tremendous entrepreneurial experience within the Company, as well as a team of seasoned industry players to guide the development of the platform technologies and product companies to bring new treatments to patients," Kugan Sathiyanandarajah, the managing director at KKR who also had a board seat at Replay said.

The other companies that invested in the seed funding are ARTIS Ventures, Lansdowne Partners, SALT, Axial and DeciBio Ventures. KKR is investing through the KKR Health Care Strategic Growth Fund II, which focuses on high-growth health care firms. Replay's headquarters are San Diego, California and London, United Kingdom.

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The amniotic products market is expected to grow from US$ – GlobeNewswire

Posted: July 27, 2022 at 2:17 am

New York, July 21, 2022 (GLOBE NEWSWIRE) -- Reportlinker.com announces the release of the report "Amniotic Products Market Forecast to 2028 - COVID-19 Impact and Global Analysis By Type, Application, End User, and Geography" - https://www.reportlinker.com/p06295644/?utm_source=GNW The amniotic membrane and suspension are two products that can be used for treatment.

The amniotic membrane is the innermost layer of the placenta that nourishes and maintains an unborn child. Amniotic fluid is the liquid that surrounds the baby until delivery.Due to the high prevalence of burn wounds, demand for wound care biologics, such as amniotic membranes, has increased significantly.According to the WHO, many burn cases occur in low- and middle-income countries, with over 2-3rd occurring in the WHO African and Southeast Asian areas.

Every year, one million people in India suffer from mild to severe burns (Source: WHO).Other Southeast Asian countries, such as Bangladesh and Nepal, have a high rate of burn cases.

An estimated 173,000 children in Bangladesh yearly suffer from moderate to severe burns. Burn is Nepals second most prevalent injury, accounting for 5% of disability cases.Based on type, the amniotic products market has been bifurcated into amniotic membranes and amniotic suspensions.The amniotic membranes segment is likely to hold the largest share of the market in 2022.

The amniotic membrane segment growth is growing due to increasing research in stem cell and regenerative medicine, high R&D investments, and an increase in the number of surgeries conducted globally.Further, they are commonly employed in the treatment of bacterial keratitis, corneal ulcers, cataract, glaucoma, bullous keratopathy, corneal degeneration, ocular dystrophy, eyelid reconstruction, and other eye surface problems.

The expansion in the worlds senior population increases the number of ophthalmology surgeries, , resulting in a growing need for tissue-based products.Further, PalinGen, Fl?Graft, AmbioDisk, and AmnioFix are examples of commercially available dehydrated amniotic membranes.

In addition, these membranes are widely used in the treatment and management of surgical wounds and incisions, owing to properties such as their ability to maintain a watertight seal, inhibit inflammatory responses, and prevent disease transmissions. Hence, these factors are driving the segment growth.In December 2016, the US passed the 21st Century Cures Act.This new law was passed with the goal of advancing regenerative medicine research and medical innovation.

The Act contains a number of provisions that could impact the development and approval of many products in the coming years.A new "Regenerative Medicine Advanced Therapy" classification and a fast-track approval procedure for innovative regenerative medicine products and therapies have been developed due to this Act.

The passage of this Act could lead to the approval of new regenerative medicine products and therapies in the US and a boost in regenerative medicine research and development.It was designed to promote patient access to electronic health information, advance innovation, and address information blocking practices.

The 21st Century Cures Act was created to help speed up medication development and approval processes, allowing for faster and more efficient delivery of new medical advancements to patients. These requirements are expected to improve interoperability and facilitate electronic health information access, exchange, and use.A few key primary and secondary sources referred to while preparing the report on the prostate cancer nuclear medicine diagnostics market are the World Health Organization (WHO), the Centers for Disease Control and Prevention, and the National Programme for Prevention, Management and Rehabilitation of Burn Injuries.Read the full report: https://www.reportlinker.com/p06295644/?utm_source=GNW

About ReportlinkerReportLinker is an award-winning market research solution. Reportlinker finds and organizes the latest industry data so you get all the market research you need - instantly, in one place.

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The amniotic products market is expected to grow from US$ - GlobeNewswire

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