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Category Archives: Kentucky Stem Cells

Mesenchymal Stem Cells | National Stem Cell Foundation

Posted: October 27, 2014 at 3:53 pm

Mesenchymal (stromal) stem cells give rise to a variety of cell types, including bone cells (osteocytes), cartilage cells (chondrocytes), fat cells (adipocytes), pancreatic islet cells and connective tissue cells such as those found in tendons.

Mesenchymal stem cells can be found in umbilical cord blood, fat, muscleand the pulp of baby teeth. They are referred to as multipotent cells because they can develop into multiple tissues, but they do not have the capacity to reconstitute an entire organ.

An extremely rich source of mesenchymal stem cells is the developing tooth bud of the mandibular (lower) third molar, or wisdom tooth. While considered multipotent, these stem cells may prove to be pluripotent, capable of generating all tissue types. The stem cells found in developing third molars eventually form enamel, dentin, blood vessels, dental pulp, nervous tissue and a minimum of 29 different unique tissues and organs. Because of extreme ease in collection at 810 years of age, they will probably constitute a major source for personal banking, research and multiple therapies.

Adipose (fat) tissue is one of the richest sources of mesenchymal stem cells. There are 500 times more mesenchymal stem cells in 1 gram of fat than there are in 1 gram of bone marrow.

Mesenchymal stem cells are of intense therapeutic interest because they represent a population of cells with the potential to treat a wide range of acute and degenerative diseases.

Because they give rise to so many tissue types, mesenchymal stem cells add significantly to the field of regenerative repair. In addition to assisting the function of bone marrow and adipose (fat) derived stem cells, recent advances include the use of mesenchymal stem cells to:

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Stem Cell Therapy KY – Be Medispa

Posted: October 15, 2014 at 5:52 am

Stem cell treatments are a type of cell therapy that introduce new cells into damaged tissue in order to treat a disease or injury. Many medical researchers believe that stem cell treatments have the potential to change the face of human disease and alleviate suffering. The ability of stem cells to self-renew and give rise to subsequent generations that can differentiate [1] offers a large potential to culture tissues that can replace diseased and damaged tissues in the body, without the risk of rejection.

A number of stem cell treatments exist, although most are still experimental and/or costly, with the notable exception of bone marrow transplantation. Medical researchers anticipate one day being able to use technologies derived from adult and embryonic stem cell research to treat cancer, Type 1 diabetes mellitus, Parkinson's disease, Huntington's disease, cardiac failure, muscle damage and neurological disorders, along with many others.

More research is needed concerning both stem cell behavior and the mechanisms of the diseases they could be used to treat before most of these experimental treatments become realities.

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How Do Stem Cells Differentiate? | eHow

Posted: September 27, 2014 at 8:51 am

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Roxann Schroeder

Roxann Schroeder, Ph.D, has been a science writer and editor for over 10 years. Her experience includes research articles, grants, theses, dissertations, web sites, text books and book chapters. She also teaches biology and grant writing at the local university.

Stem cells have two functions; they divide (proliferate) and their daughter cells become specialized tissues as they lose the ability to divide. This change-from a dividing cell to a specialized cell-is called differentiation.

When stem cells divide into two cells, one cell is still a stem cell (self-renewal); the other is a daughter cell that starts to become specialized.

Embryonic stem cells are totipotent, meaning they can give rise to any and all tissues in the body. Adult stem cells are usually multipotent, meaning they can differentiate into some, but not all, cell types.

Each time a daughter cell divides, it become more specialized (differentiated); eventually, it can no longer divide.

When daughter cells are fully differentiated (mature), they have functions not found in the stem cell; muscle cells contract, gland cells secrete molecules, blood cells carry oxygen and skin cells protect the body.

The liver can regenerate from a small fragment; until recently, the only neurons known to regenerate were odor receptors. Stem cells have been found in many tissues, but not all tissues have the same ability to regenerate.

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Stem Cell Laboratory – Rood and Riddle

Posted: September 27, 2014 at 8:51 am

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Stem Cell Laboratory

The Rood & Riddle Stem Cell Laboratory is the latest addition to the hospitals medical services. Rood & Riddle collaborated with the Regenerative Medicine Laboratory at the University of California-Davis Veterinary Medical Teaching Hospital in the planning of this state of the art facility. The addition of the stem cell service is part of Rood & Riddles ongoing effort to provide the most up to date technologies and treatments for their patients.

A thorough lameness examination and definitive diagnosis are needed to determine if a horse is a suitable candidate for stem cell therapy. For some tendon and ligament injuries, initial stem cell therapy may begin with a dose of bone marrow concentrate. This service is available within an hour of the initial bone marrow collection. Rood & Riddles Stem Cell Lab also uses established stem cell processing techniques to culture and expand (grow) large numbers of stem cells needed for multiple therapeutic doses in a relatively short amount of time. With each bone marrow or umbilical cord blood sample, a total of four 10-million cell doses will be obtained for treatment and long term storage. Since multiple treatments can enhance response to therapy, there are notable benefits to culture and expansion, including a significant increase in stem cell numbers in 2-3 weeks providing doses from 10-40 million cells, resulting in multiple doses without collecting additional bone marrow.

Stem cell banking allows for cultured stem cells to be cryopreserved and readily available if an injury occurs. Stored stem cells can be quickly thawed, shipped and ready for injection within 72-96 hours with no additional collection required. The first year of storage is included in any stem cell expansion order.

Rood & Riddle is excited to join the leaders in equine regenerative cell medicine and committed to furthering the science of stem cell therapy through support of academic stem cell research and performing clinical trials. Our veterinarians are available to answer any questions in this emerging field.

The Rood & Riddle Stem Cell Laboratory Services:

Forms to Download

Stem Cell Processing Form (PDF)

Contact one of our professionals to schedule an appointment.

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Worlds first tendon replacement using Nanofiber and activated MediVet Stem Cell Fraction

Posted: September 20, 2014 at 1:48 pm

Friesland, Netherlands (PRWEB) September 20, 2014

MediVet America and NanoFiber Veterinary combined stem cell technologies to perform a groundbreaking surgery at the specialized Wolvega Horse Clinic.

Due to a serious incident, the mare's superficial digital flexor tendon was ruptured 90% and her deep digital flexor tendon 50%. Typically, this kind of injury is a death sentence for a horse.

The clinic has performed numerous successful MediVet America stem cell treatments. This revolutionary regenerative option for ruptured tendons has only been performed once in the United States, but the results were very promising. Together with MediVet's European team, two 20 cm long Nanofiber replacement tendons where created and seeded with MediVets patented activated Stem Cell Fraction. These first generation stem cells allow for acute treatment in-clinic.

Dr.s Don van Winkel and Aart Schutrups, two equine surgeons, performed the breakthrough procedure. Once on the operating table, they found the injury worse than expected. Dr.s van Winkel and Schutrups successfully connected the scaffolds seeded with the mares own stem cells to the remaining threads of original tendons. The two replacement tendons serve as scaffolds for the stem cells that where harvested through a liposuction technique and then isolated using MediVets patented in-clinic stem cell isolation and activation technology. Within the next few months, the stem cells will regenerate the lost tissue along the 3D Nanofiber scaffolds and restore functional tendons. After nine months the Nanofiber scaffolds will have been broken down and replaced by functional tendons. The Nanofiber scaffolds can also be used for extensive internal and external wounds, tendon and ligament injuries, bone regeneration and more.

About MediVet America: MediVet is a global leader in veterinary regenerative medicine with over 1,000 clinics practicing this incredible technology in the US, Mexico, Canada and 28 other countries. Headquartered in Lexington, Kentucky, MediVet America develops advanced cellular treatments designed to maximize animal performance, repair, recovery and general wellness. MediVet America's Adipose-Derived Stem Cell procedure kit is a major scientific advancement in animal stem cell regenerative therapy that offers an affordable solution for owners of pets suffering from osteoarthritis, hip dysplasia, ligament and cartilage injuries and similar ailments. MediVets global initiatives include providing veterinarians around the world access to novel treatments based in science at an affordable cost to owners.

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Stem Cell Scandal

Posted: August 30, 2014 at 12:54 am

Michael Stitzel joked that his research has led him to climb up the evolutionary tree. As an undergraduate he worked with yeast, and over the years, he has worked his way up to studying Drosophila, C. elegans, and, now, people.

Stitzel shifted from the more basic roots of the tree to the biomedical limbs as a matter of motivation. He said that as a graduate student, though he worked on an important and interesting question, when experiments didn't go well, it was hard for him to get motivated. And so, he found himself drawn to questions with more direct relevance to medicine.

He turned to studying type 2 diabetes. Using a genome-wide association study approach, he identified a number of regions in the genome linked to the disease, but many of them were, as he put it, "in the middle of nowhere." This led him to thinking about epigenetics, and then to later uncover what he and his colleagues dubbed 'stretch enhancers,' longer-than-average enhancers that appear to be driving physiological functions.

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Stem Cell Scandal

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STEM CELL SUCCESS STORIES Archives …

Posted: August 23, 2014 at 10:00 am

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Harold Atkins treated Jennifer Molsons MS

At 21, multiple sclerosis (MS) had Jennifer Molson wheelchair bound. But since her stem cell transplant, she has worked, driven, danced at her own wedding.

The story had a room of 1,000 professional stem cell scientists sniffling at the International Society for Stem Cell Research (ISSCR) meetingsaid sniffling reaching a crescendo when the quiet, pretty Molson concluded: Im living proof stem cells can save lives.

Diagnosed with Relapsing Remitting MS, Molson had failed many standard treatments when she tried a hematopoietic stem cell transplant (HSCT, or bone marrow transplant (BMT)) in 2002, as part of a clinical trial.

That trial, firstreportedon in 2013 by three Canadian centers, has seen dramatic results:noneof the trials 14 immuno-monitoring sub-study patients saw remissions in the first two years. The transplants halted all new focal inflammatory MS disease, verified by both medical examinations and brain MRIs. A paper on a larger cohort of 24 patients is being compiled.

There have been500MS HSCTs worldwide. MS is an inflammatory autoimmune disease in which the immune system is thought to attack its own nervous system via the myelin protecting nerve fibers.

Results globally have been mixed. Indeed, Molsons doctors, Ottowa Hospitals Harold Atkins and Mark Freedman, wrote in a2012 reviewthat although a few patients have had dramatic improvements after HSCT, most reports of improvement are modest.

Not so in this study. One reason, Atkins conjectured in a recent email toBioscience Technology: a more intense regimen than usual was used to wipe out the immune system of Molson and the other Canadian patients.

Globally, the trend was toward more non-myeloablative approaches. But while gentler, these may not ablate enough immune cells trained on attacking self-antigen. Self-antigen are proteins on cells marking them as self.

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Genetic Disease Stem Cell Research, MS Treatments …

Posted: August 23, 2014 at 10:00 am

If you are interested in Stem Cell Therapy you can contact us directly at: (631) 929-3900

Or please go to our "Contact Us" page to send us an email about the condition you are inquiring about.

Stem Cells for Hope Provides Adult Stem Cell Transplantation Therapy for Texas Woman with RR Multiple Sclerosis and Optic Neuritis

In October of 2008, Angela, a Customer Service Representative from Austin, Texas, was diagnosed with Relapsing Remitting Multiple Sclerosis (RRMS) and Optic Nerve Atrophy. A disabling disease, RRMS is characterized by optic disturbances, muscle weakness, paralysis, impaired speech, vertigo, and a host of other crippling conditions. Having received no relief from conventional treatment methods in the U.S., in February 2010, Angela left the country to begin a five day treatment at Stem Cells for Hopes affiliate treatment clinic in Mexico.

(This is a journal that Angela, a Stem Cells for Hope RRMS & Optic Neuritis Patient wrote while she was at our Treatment Facility in Mexico. She has given us permission to publish this Journal as well as her email address below so that she can discuss her experience with Stem Cell Transplantation Therapy. It is a long read but worth it, enjoy)

February 21st, 2010

I awakened this morning nauseous. I should be excited, and in many ways I am, as this is the day I traveled to Mexico in hopes to regain health Ive lost to Multiple Sclerosis. I also hope to retrieve the life this disease has stolen from me. I know most of my stomach issues related to my anxiety about flying. Though I understand the physics behind flying, it still seems unnatural to me to be that high up in the air. I mean, Im over 200lbs. and I dont fly (LOL). Though I was a nervous wreck at takeoff, I have to admit the flight was not as horrible as I thought it would be and I handled my stress well.

I realize a lot of my unease also related to the larger picture at hand I will be facing this week and the coming days which follow. I have spent six months building my faith that this procedure will be the answer in repairing the damage MS has done to me physically. I really dont want to be disappointed. On the one hand I want this to work; however, if it does I have so many things in my life to face in terms of getting back to work and getting my life back. If it doesnt work, life will be more living with an illness that is nothing more than a series of mysteries. MS appears to be the Polio of the modern era.

I must be really tired and anxious here in Tijuana as I am full of internal conflict. Actually this is nothing new for me since Ive been diagnosed; perhaps tonight it is just more intense with tomorrow being day number one. I am really nervous about the procedure for my eye and how all that will play out. I never thought I would have an illness that could take my vision; so I definitely never dreamed I would require a procedure that would place a needle in my eye in an attempt to return my vision. What a crazy, wild ride this existence we call life can be.

While I sit here writing about my thoughts, I am deeply grateful for this opportunity no matter how anxious and nervous I am. It is the hope I now have that it is possible to regain my health I hold in my heart to influence my dreams tonight. Tomorrow is not merely just a new day but hopefully the start of a new life and future for me without the daily plague of MS extremes. Goodnight old life and hopefully goodbye to MS.

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Genetic Disease Stem Cell Research, MS Treatments ...

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Kentucky Stem Cell Treatment and therapy | Stem Cell …

Posted: August 22, 2014 at 5:57 am

Kentucky Stem Cell Treatment Worldstemcells.com is one of the leading stem cell therapy and treatment providers for residents of Kentucky and across the nation. Our cutting edge technology and compassionate staff truly set us apart from the competition. We are a US based company that understands your needs and concerns when looking for a stem cell treatment center. Our treatment center is located in Cancun, Mexico.

Conditions we treat include but not limited to:

Getting Started With Your Stem Cell Therapy and Treatments Here at World Stem Cells LLC we try to make the process of receiving stem cell transplants as easy as possible. We will help you figure out what your needs are and help you reach your goals as fast as possible. Follow the steps below on what to do.

Option 1 1.) Go to any page on our website and fill out the contact form. 2.) Fill in the required information and select the condition you would like to treat with stem cell therapy. 3.) Be sure to include any special information in the comments section. 4.) Click the submit button and we will contact you in a timely manner. 5.) Thats it, youre done!!!

REQUEST INFORMATION NOW!

Option 2

Call 800-234-1693 and speak with a representative regarding your stem cell therapy needs and requirements.

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Kentucky Stem Cell Treatment and therapy | Stem Cell ...

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Kentucky Stem Cell Treatment | Stem Cell Treatments

Posted: August 22, 2014 at 5:57 am

Kentucky Stem Cell Treatment Worldstemcells.com is one of the leading stem cell therapy and treatment providers for residents of Kentucky and across the nation. Our cutting edge technology and compassionate staff truly set us apart from the competition. We are a US based company that understands your needs and concerns when looking for a stem cell treatment center. Our treatment center is located in Cancun, Mexico.

Conditions we treat include but not limited to:

Getting Started With Your Stem Cell Therapy and Treatments Here at World Stem Cells LLC we try to make the process of receiving stem cell transplants as easy as possible. We will help you figure out what your needs are and help you reach your goals as fast as possible. Follow the steps below on what to do.

Option 1 1.) Go to any page on our website and fill out the contact form. 2.) Fill in the required information and select the condition you would like to treat with stem cell therapy. 3.) Be sure to include any special information in the comments section. 4.) Click the submit button and we will contact you in a timely manner. 5.) Thats it, youre done!!!

REQUEST INFORMATION NOW!

Option 2

Call 800-234-1693 and speak with a representative regarding your stem cell therapy needs and requirements.

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Kentucky Stem Cell Treatment | Stem Cell Treatments

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