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Category Archives: Illinois Stem Cells

Babys Cells Can Manipulate Moms Body for Decades

Posted: July 3, 2022 at 2:40 am

Sure, it looks cute now, but a new study explores why babies influence their moms' DNA for years. PeopleImages/iStock

Mothers around the world say they feel like their children are still a part of them long after they've given birth. As it turns out, that is literally true. During pregnancy, cells from the fetus cross the placenta and enter the mother's body, where they can become part of her tissues.

This cellular invasion means that mothers carry unique genetic material from their childrens bodies, creating what biologists call a microchimera, named after the legendary beasts made of different animals. The phenomenon is widespread among mammals, and scientists have proposed a number of theories for how it affects the mother, from better wound healing to higher risk of cancer.

Now a team of biologists argues that to really understand what microchimerism does to moms, we need to figure out why it evolved in the first place.

What we are hoping to do is not only provide an evolutionary framework for understanding how and why microchimerism came to be, but also to assess how this affects health, says lead author Amy Boddy, a geneticist at Arizona State University.

Maternal-fetal conflict has its origins with the very first placental mammals millions of years ago. Over evolutionary time, the fetus has evolved to manipulate the mother's physiology and increase the transfer of resources like nutrition and heat to the developing child. The mother's body in turn has evolved countermeasures to prevent excessive resource flow.

Things get even more intriguing when fetal cells cross the placenta and enter the mother's bloodstream. Like stem cells, fetal cells are pluripotent, which means they can grow into many kinds of tissue. Once in the mother's blood, these cells circulate in the body and lodge themselves in tissue. They then use chemical cues from neighboring cells to grow into the same stuff as the surrounding tissue, Boddy says.

Although the mother's immune system typically removes unchanged fetal cells from the blood after pregnancy, the ones that have already integrated with maternal tissues escape detection and can remain in mom's body.

Microchimerism can get especially complex when a mother has multiple pregnancies. The mother's body accumulates cells from each babyand potentially functions as a reservoir, transferring cells from the older sibling into the younger one and forming more elaborate microchimeras. The presence of fetal cells in the mothers body could even regulate how soon she can get pregnant again.

I think one promising area for further research concerns unexplained pregnancy losses, and whether older siblings, as genetic individuals, can play a role in delaying the birth of younger siblings, says David Haig, an evolutionary biologist at Harvard University.

Given all this complexity, microchimeras have been difficult to study until recently, the authors note in their paper, which will be published in an upcoming issue of BioEssays. The phenomenon was discovered several decades ago, when male DNA was detected in the bloodstream of a woman. But the technologies of the time couldn't get a detailed enough picture of the genetics to tease apart the minute cellular situation.

Now, deep-sequencing technologies allow researchers to identify the origin of DNA in a mother tissues more comprehensively by sampling many areas in the genome, including genes implicated in immunity. These genes are unique to an individual and thus can help differentiate a mothers DNA from that of her children with greater precision.

If the cell populations can be isolated, then modern techniques should allow the genetic individual of origin to be unambiguously identified, says Haig.

Still, understanding how the fetal cells are interacting with maternal cells is going to be difficult, says Boddy. Little is understood about the cellular signaling that causes fetal cells to regulate maternal physiology.

Its likely a negotiation between the maternal body and the fetal cells, where there is an expectation in the maternal body of a certain level of microchimerism that it needs to function properly, said Boddy. For example, previous experiments showed that when mouse fetal cells are exposed to lactation hormones in the lab, they take on similar attributes to those of mammary cells, hinting that breast tissue may be one hot spot for microchimerism.

Normal, healthy lactation may be the consequence of the fetal cells signaling to the mothers body to make milk, says co-author Melissa Wilson Sayres, also at Arizona State. But previous work has also suggested that the same features that allow fetal cells to integrate into the mothers tissueslike evading her immune systemalso makes them similar to cancer cells, which could lead to greater cancer vulnerability in the mother.

Based on evolutionary reasoning, the authors predict that fetal cells should be found primarily in the tissues that play a role in transferring resources to the fetus. That includes the breast, where they may impact milk production; the thyroid, where they can affect metabolism and heat transfer to the baby; and the brain, where they may influence neural circuitry and maternal attachment to the child.

The next steps will be to use modern sequencing tools to go looking for fetal cells in these spots, and then begin studying how the cells are communicating in each region of mom's body.

What is really interesting and novel about this work is putting the issue of microchimerism and maternal health into an evolutionary framework, says Julienne Rutherford, a biological anthropologist at the University of Illinois at Chicago.

If these fetal cells are interacting with maternal physiology, where in the maternal body would we expect the greatest effect on function? Thats been a big question mark. Putting this into an evolutionary context was incredibly clever and novel and very exciting. Its a beautiful example of theory driving testable predictions."

EDITOR'S NOTE: This story has been updated to clarify the results of the study on mouse fetal cells and mammary tissue.

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Babys Cells Can Manipulate Moms Body for Decades

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Cell Expansion Market Projection By Top Key Players, Regional Analysis Revenue Forecast Till 2030 Designer Women – Designer Women

Posted: July 3, 2022 at 2:40 am

New York(United States):- According to Report Ocean research report Global Cell Expansion Market: Analysis By Product Type (Instruments, Consumables, Disposables), By Cell Type (Human Cell and Animal Cell), By Application (Regenerative Medicine & Stem Cell Research and Cancer & Cell Based Research), By Region (North America, Europe, Asia Pacific, South America, and Middle East & Africa), (U.S, Canada, Germany, France, U.K., Japan, China, India): Opportunities and Forecast (2019 Edition): Forecast to 2024-, the cell expansion market is projected to display a robust growth represented by a CAGR of 17.33% during 2019 2024.

A comprehensive research report created through extensive primary research (inputs from industry experts, companies, stakeholders) and secondary research, the report aims to present the analysis of cell expansion market. The report analyses the Global Cell Expansion Market: Analysis By Product Type (Instruments, Consumables, Disposables), By Cell Type (Human Cell and Animal Cell), By Application (Regenerative Medicine & Stem Cell Research and Cancer & Cell Based Research), By Region (North America, Europe, Asia Pacific, South America, and Middle East & Africa), (U.S, Canada, Germany, France, U.K., Japan, China, India): Opportunities and Forecast (2019 Edition): Forecast to 2024, for the historical period of 2018-2019 and the forecast period of 2019-2024.

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Over the recent years, cell expansion market has been witnessing considerable growth directly on the back of increasing prevalence of chronic diseases such as cancer, diabetes, osteoarthritis, etc. Moreover, factors such as increasing investment in healthcare research, growing government initiatives, increasing adoption rate of new and technically instruments, rapidly evolving applicable segment market has been providing momentum to the overall market growth of cell expansion.

In addition, increasing demand for technically advanced products such as automated cell expansion systems and increasing number of cell GMP-certified cell expansion facilities are anticipated to fuel the market growth in forecasted period. However, recalls due to product failures have been hindering the market growth.

The report titled Global Cell Expansion Market: Analysis By Product Type (Instruments, Consumables, Disposables), By Cell Type (Human Cell and Animal Cell), By Application (Regenerative Medicine & Stem Cell Research and Cancer & Cell Based Research), By Region (North America, Europe, Asia Pacific, South America, and Middle East & Africa), (U.S, Canada, Germany, France, U.K., Japan, China, India): Opportunities and Forecast (2019 Edition): Forecast to 2024:-has covered and analysed the potential of cell expansion market and provides statistics and information on market size, shares and growth factors. The report intends to provide cutting-edge market intelligence and help decision makers take sound investment evaluation. Besides, the report also identifies and analyses the emerging trends along with major drivers, challenges and opportunities. Additionally, the report also highlights market entry strategies for various companies.

Scope of the Report

Global Cell Expansion Market (Actual Period: 2014-2018, Forecast Period: 2019-2024)

Cell Expansion Market Size, Growth, ForecastAnalysis By Product Type:Instruments, Consumables, Disposables.Analysis By Cell Type:Human Cells and Animal Cells.Analysis By Application Type:Regenerative Medicine & Stem Cell Research and Cancer & Cell Based Research.Regional Cell Expansion Market North America, Europe, Asia Pacific, South America, and Middle East & Africa (Actual Period: 2014-2018, Forecast Period: 2019-2024)

Cell Expansion Market Size, Growth, ForecastAnalysis By Product Type: Instruments, Consumables, Disposables.Analysis By Cell Type:Human Cells and Animal Cells.Analysis By Application Type:Regenerative Medicine & Stem Cell Research and Cancer & Cell Based Research.Country Cell Expansion Market U.S., Canada, Germany, U.K, France, China, Japan, India (Actual Period: 2014-2018, Forecast Period: 2019-2024)

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Cell Expansion Market Size, Growth, ForecastAnalysis By Product Type: Instruments, Consumables, Disposables.Analysis By Cell Type:Human Cells and Animal Cells.Analysis By Application Type:Regenerative Medicine & Stem Cell Research and Cancer & Cell Based Research.

Other Report HighlightsMarket Dynamics Drivers and Restraints.Market Trends.Porter Five Forces Analysis.SWOT Analysis.

Company Analysis Merck Millipore, Eppendorf, ThermoFisher Scientific, Becton Dickinson, Danaher Corporation, Corning Inc., Terumo Medical Corporation, CellGenix Technologie Transfer GmbH, Synthecon Inc., Stem Cell Technologies Inc.

Table of Content:

Key Questions Answered in the Market Report

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Agriculture companies have lots of job openings in STEM fields, far from the farm – Illinois Newsroom

Posted: June 22, 2022 at 2:07 am

Agriculture companies are looking for people who are interested in science, and hiring managers are increasingly looking for people who dont have traditional ag backgrounds.

ST. LOUIS Jobs in agriculture dont just take place on the farm.

Across the Midwest, plant science and ag companies are looking for scientists and others in STEM to fill positions in labs, or in front of computers, that may not fit the traditional image of agriculture.

Listen to this story here.

When people meet folks that work in the ag industry, theyre often shocked about what they actually do for a living, said Kim Kidwell, the associate chancellor of Strategic Partnerships and Initiatives at the University of Illinois, Urbana-Champaign and a former dean of the School of Agriculture. Theres a lot of engineering, theres a lot of business, theres a lot of computer science.

Across the industry, theres a growing need for scientists at every level as agriculture becomes more high-tech, and employers are increasingly looking for people who dont have a traditional ag background for different positions.

Corteva Agriscience is a global company that produces agriculture products like seeds and chemicals. The company has about 500 open jobs right now, from scientists to data engineers. About 200 of those dont require a four-year degree. Many of the openings are in Nebraska, Indiana, Michigan and Iowa.

People think of Corteva obviously as an ag company and they think that they have to have an agriculture degree, an agronomy degree or an ag business degree to come work for us, and thats far from the truth, said Angela Latcham, who leads Cortevas North America seed production and supply chain teams. Were looking for people with nontraditional backgrounds.

Corteva has open positions all over the country and the world. Some are in rural areas, close to the fields where they grow their crops, but thats not the case for most jobs in agriculture.

Agricultural economists at Purdue University have been analyzing online job openings and have found about two-thirds are in metropolitan areas.

Most of the jobs are actually not on the farm, said Brady Brewer, an associate professor of agricultural economics at Purdue.

The need for workers with non-traditional backgrounds also extends to education. Kidwell, of the University of Illinois, said theres an incredible demand for scientists at every level, including for positions that dont require a four-year degree.

If we dont get more people into the pipe, whats coming out of the pipeline will be grossly inadequate to support the advancement of food and ag in the way that it has the potential to expand, she said.

Growing the ag workforce

In St. Louis, one community college program is trying to help fill the worker gap by training students to work in labs. St. Louis Community Colleges Center for Plant and Life Sciences is a hands-on program. In fact, many of the classes take place at the Donald Danforth Plant Science Center, where scientists study plants and find ways to apply their knowledge to agriculture.

The centers director, Elizabeth Boedeker, was leading a lab exercise with her students on a recent afternoon where they were working with cells.

There is a huge workforce demand right now, Boedeker said. These two-year students that are doing their internships, about a third of the time those students get offered full time or permanent part time employment with those internship sponsors.

The types of positions Boedeker is training students for, like agriculture and food science technician roles, are still a much smaller group compared to farm workers, but according to the Bureau of Labor Statistics, those science jobs are projected to grow much faster in the coming years than traditional farm worker jobs.

Boedekers students complete internships as part of their coursework, often with some of the many plant science startups and big companies that operate in the area.

NewLeaf Symbiotics is one company that regularly hires the interns through the community college program. The biotechnology startup is conveniently located in the same building where classes take place.

The company makes what Natalie Breakfield, vice president for research and discovery, describes as basically a probiotic for a plant.

Breakfield has a Ph.D., but she said many positions at the company can be filled by someone who has gone through an associates or technical training program, like the one through St. Louis Community College. These research assistants do hands-on lab work, collecting data and running experiments, while being supervised by another scientist.

I know when I need an employee, I can call up [Boedeker] and ask her, who does she have available right now thats looking for a job, and she can send me a few resumes right away, Breakfield said.

As St. Louis works to become a hub for ag biotech companies, Breakfield said theyre going to need more and more people in jobs like these. But one barrier to expansion is that people might not know these careers exist.

Even Breakfield said she didnt know much about the plant science field before her first job as a lab technician.

That was my first real introduction into working with plants and then I actually just fell in love with it, she said. I think if you like science, this is a good place to start and you can always go on further if you decide you want to further your education.

Follow Kate on Twitter: @KGrumke This story was produced in partnership with Harvest Public Media, a collaboration of public media newsrooms in the Midwest. It reports on food systems, agriculture and rural issues. Follow Harvest on Twitter: @harvestpm

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3D Cell Culture Market Size, Trends, Share, Research Report Study, Regional and Industry Analysis, Forecast to 2030 The Greater Binghamton Business…

Posted: June 4, 2022 at 2:27 am

United StatesReport Oceanpublished a new report on the3D Cell Culture Market The study includes an in-depth analysis of regional trends and market growth in North America, Europe, Asia-Pacific, and Middle East Africa. This study report also examines the challenges that are negatively impacting the industrys growth and outlines a strategy adopted by companies during 2022 to 2030.

Global 3D Cell Culture Market is estimated to reach $4,899 billion by 2024; growing at a CAGR of 23.3% from 2016 to 2024.

3D cell culture is the culture of biological cells in micro-assembles devices, where artificially created three-dimensional environment supports the growth of these cells. The micro-environment parameters of these growing cells can be controlled and monitored to a certain extent. Driven by advancements in the field of cell imaging and analytical systems, cells have been increasingly grown in 3D cell culture and have proved to be useful in many applications. Moreover, they are widely used in tissue engineering and drug discovery, owing to its ability to provide physiologically relevant and accurate data for various in-vivo test. 3D cell culture is widely used in various application such as, disease pathology, tissue morphogenesis and engineering, gene and protein expression, regenerative medicine, and others.

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Increase in investment by pharmaceutical and biotechnology companies on 3Dcell culture, and growth in number of patients in need for organ transplantation are the key factors supporting the growth of the global 3D cell culture market. Moreover, ban on animal research and testing is also expected to drive 3D cell culture across various applications. However, high initial investments may restrain the growth of the market. Furthermore, development of 3D cell culture for formulating personalized cosmetics would provide growth opportunities for the market in the near future.

The global 3D cell culture market is categorized into technology, application, and end-user. By technology, the market is segmented into extracellular matrices, bioreactors, gels, Scaffold free platform, and microchips. By application, the market is sub-segmented into research, drug discovery, tissue engineering, clinical applications, and stem cell biology. Furthermore, end-user is segmented into research laboratories & institutes, biotechnology & biopharmaceutical industry, and hospital & diagnostic centers.

By geography, the market has been bifurcated into North America, Europe, Asia-Pacific, and Rest of the World (RoW). The U.S., Canada, and Mexico are covered under North America wherein Europe covers UK, Germany, France Italy, and others. Asia-Pacific covers China, Japan, India, South Korea, and others. RoW covers South America, Middle East, and Africa.

Key market players comprise Merck & Co., Inc., 3D Biotek LLC, Lonza Group, Kuraray Co., Ltd., Corning Incorporated, Becton, Dickinson and Company, Advanced Biomatrix, Inc., Thermo Fisher Scientific Inc., VWR International, LLC, and Global Cell Solutions, Inc., among others.

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The key takeaways from the reportThe report will provide a detailed analysis of Global 3D Cell Culture Market with respect to major segments such as technology, application, end-user, and geographyThe report will include the qualitative and quantitative analysis with market estimation over 2015-2024 and compound annual growth rate (CAGR) between 2016 and 2024Comprehensive analysis of market dynamics including factors and opportunities will be provided in the reportAn exhaustive regional analysis of Global 3D Cell Culture Market from 2015 to 2024 has been included in the reportProfile of the key players in the Global 3D Cell Culture Market will be provided, which include key financials, product & services, new developments, and business strategiesScope of the Global 3D Cell Culture MarketTechnology Segments

Extracellular MatricesBioreactorsGelsScaffold Free PlatformMicrochipsApplication Segments

ResearchDrug DiscoveryTissue EngineeringClinical ApplicationsStem Cell BiologyEnd-User Segments

Research Laboratories & InstitutesBiotechnology & Biopharmaceutical IndustryHospital & Diagnostic Centers

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North AmericaU.S.CanadaMexicoEuropeUKGermanyFranceItalyOthersAsia-PacificIndiaChinaJapanSouth KoreaOthersRoWSouth AmericaMiddle EastAfrica

Table of content:

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Key Questions Answered in the Market Report

? How did the COVID-19 pandemic impact the adoption of by various pharmaceutical and life sciences companies?? What is the outlook for the impact market during the forecast period 2021-2030?? What are the key trends influencing the impact market? How will they influence the market in short-, mid-, and long-term duration?? What is the end user perception toward?? How is the patent landscape for pharmaceutical quality? Which country/cluster witnessed the highest patent filing from January 2014-June 2021?? What are the key factors impacting the impact market? What will be their impact in short-, mid-, and long-term duration?? What are the key opportunities areas in the impact market? What is their potential in short-, mid-, and long-term duration?? What are the key strategies adopted by companies in the impact market?? What are the key application areas of the impact market? Which application is expected to hold the highest growth potential during the forecast period 2021-2030?? What is the preferred deployment model for the impact? What is the growth potential of various deployment models present in the market?? Who are the key end users of pharmaceutical quality? What is their respective share in the impact market?? Which regional market is expected to hold the highest growth potential in the impact market during the forecast period 2021-2030?? Which are the key players in the impact market?

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3D Cell Culture Market Size, Trends, Share, Research Report Study, Regional and Industry Analysis, Forecast to 2030 The Greater Binghamton Business...

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Primary Cells Market 2022 Share, Upcoming Trends, Growth Analysis, Latest Technology by 2030 |PromoCell GmbH, HemaCare Corporation, Thermo Fisher…

Posted: May 15, 2022 at 1:57 am

Primary Cells Marketreport contains detailed information on factors influencing demand, growth, opportunities, challenges, and restraints. It provides detailed information about the structure and prospects for global and regional industries. In addition, the report includes data on research & development, new product launches, product responses from the global and local markets by leading players. The structured analysis offers a graphical representation and a diagrammatic breakdown of thePrimary Cells Marketby region.

Primary cells market is valued approximately at USD 0.97 billion in 2020 and is anticipated to grow with a healthy growth rate of about 12.45% over the forecast period 2021-2027.

Primary cells are increasingly gaining popularity to carry out research and development activities as these cells stimulate biological living model closely and are the closest experimental tools which are available without the use of in vivo animal studies. Experiments which are performed using primary cells have potential to deliver more meaningful and relevant data as such cells are closest to real thing in terms of both, genotype and phenotype. Rise in prevalence of chronic diseases, rising research and development activities, and increasing investments in cell-based research are some of the factors that are expected to significantly contribute towards the growth of global primary cells market during the forecast period. Primary cells are used in drug screening as well as for the development of different biological compounds such as vaccines, therapeutic proteins, etc.

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Thus, helps in the prevention of chronic diseases. According to International Diabetes Federations report in 2019 diabetes patients across the globe were 463 million whose age was in the range from 20 to 79 years, which is expected to increase 700 million in 2045. This is expected to promote the market growth by increasing the demand and adoption of primary cells. In addition, increasing usage of primary cells in 3D cell culture and increasing investments in drug development and discovery provides lucrative growth opportunities to the market. However, risk of primary cell culture contamination is expected to hamper the growth of global primary cells market during the forecast years.

The regional analysis of the global primary cells market is considered for the key regions such as Asia Pacific, North America, Europe, Latin America, and Rest of the World. North America accounts for the largest share in terms of market revenue in the global primary cells market over the forecast period 2021-2027. Factors such as increasing number of market players launching new primary cells (human) for research, growing focus on research and development, expansion of the biotechnology and pharmaceutical industries, increasing prevalence of cancer, etc. contributes towards the largest market revenue share of North America. However, Asia Pacific is expected to register the fastest growth rate during the forecast period owing to factors such as increasing prevalence of chronic diseases, government funding for drug development programs, etc.

Major market player included in this report are:

PromoCell GmbH

HemaCare Corporation

Thermo Fisher Scientific, Inc.

Merck KGAA

Lonza

Corning Incorporated

American Type Culture Collection (ATCC)

Cell Biologics, Inc.

Zenbio, Inc.

Stem Cell Technologies, Inc

The objective of the study is to define market sizes of different segments & countries in recent years and to forecast the values to the coming eight years. The report is designed to incorporate both qualitative and quantitative aspects of the industry within each of the regions and countries involved in the study. Furthermore, the report also caters the detailed information about the crucial aspects such as driving factors & challenges which will define the future growth of the market. Additionally, the report shall also incorporate available opportunities in micro markets for stakeholders to invest along with the detailed analysis of competitive landscape and product offerings of key players.

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The detailed segments and sub-segment of the market are explained below:

By Origin:

Human primary cells

Animal primary cells

By Type:

Hematopoietic Cells

Dermatocytes

Gastrointestinal Cells

Hepatocytes

Lung Cells

Renal Cells

Heart Cells

Musculoskeletal Cells

Other Primary Cells

By End User:

Life Science Research Companies

Research Institutes

By Region:

North America

U.S.

Canada

Europe

UK

Germany

France

Spain

Italy

ROE

Asia Pacific

China

India

Japan

Australia

South Korea

RoAPAC

Latin America

Brazil

Mexico

Rest of the World

Furthermore, years considered for the study are as follows:

Historical year 2018, 2019

Base year 2020

Forecast period 2021 to 2027.

Target Audience of the Global Primary cells Market in Market Study:

Key Consulting Companies & Advisors

Large, medium-sized, and small enterprises

Venture capitalists

Value-Added Resellers (VARs)

Third-party knowledge providers

Investment bankers

Market Statistics:

The file offers market sizing and forecast throughout 5 primary currencies USD, EUR GBP, JPY, and AUD. It helps corporation leaders make higher choices when foreign money change records are available with ease. In this report, the years 2020 and 2021 are regarded as historic years, 2020 as the base year, 2021 as the estimated year, and years from 2022 to 2030 are viewed as the forecast period.

In order to produce a holistic assessment of the market, a variety of factors is considered, including demographics, business cycles, and microeconomic factors specific to the market under study.Healthcare Marketreport 2021 also contains a comprehensive business analysis of the state of the business, which analyzes innovative ways for business growth and describes critical factors such as prime manufacturers, production value, key regions, and growth rate.

The Centers for Medicare and Medicaid Services report that US healthcare expenditures grew by 4.6% to US$ 3.8 trillion in 2019, or US$ 11,582 per person, and accounted for 17.7% of GDP. Also, the federal government accounted for 29.0% of the total health expenditures, followed by households (28.4%). State and local governments accounted for 16.1% of total health care expenditures, while other private revenues accounted for 7.5%.

This study aims to define market sizes and forecast the values for different segments and countries in the coming eight years. The study aims to include qualitative and quantitative perspectives about the industry within the regions and countries covered in the report. The report also outlines the significant factors, such as driving factors and challenges, that will determine the markets future growth.

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What are the aspects of this report that relate to regional analysis?

About Report Ocean:We are the best market research reports provider in the industry. Report Ocean believes in providing quality reports to clients to meet the top line and bottom line goals which will boost your market share in todays competitive environment. Report Ocean is a one-stop solution for individuals, organizations, and industries that are looking for innovative market research reports.

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Primary Cells Market 2022 Share, Upcoming Trends, Growth Analysis, Latest Technology by 2030 |PromoCell GmbH, HemaCare Corporation, Thermo Fisher...

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3D Cell Culture Market Size 2022 [NEW GROWTH AVENUES] Share, Key Findings, Investment Opportunities, and Forecast till 2030 | Thermo Fisher Scientific…

Posted: May 15, 2022 at 1:57 am

Report ocean published a new report on the3D cell culturemarket. The research report consists of thorough information about demand, growth, opportunities, challenges, and restraints. In addition, it delivers an in-depth analysis of the structure and possibility of global and regional industries.

The global 3D cell culture market accounted for USD 725.15 million in 2016 and is expected to register a CAGR of 25.50% over the forecast period.

The Centers for Medicare and Medicaid Services data estimates that the U.S. national healthcare expenditure surpassed US$ 4.1 trillion in 2020 and is forecast to reach US$ 6.2 trillion by 2028. According to the Commonwealth Fund, the U.S. expended nearly 17% of gross domestic product (GDP) on healthcare in 2018. Switzerland was the second-highest-ranking country, expending 12.2%. In addition, New Zealand and Australia devote only 9.3%.

According to the U.S. Bureau of Labor Statistics, employment in healthcare fields is forecast to grow 16% from 2020 to 2030, much quicker than the standard for all occupations, counting about 2.6 million new jobs. This estimated growth is mainly due to an elder population, showing to greater demand for healthcare services. The median annual wage for healthcare practitioners and technical fields (such as registered nurses, physicians and surgeons, and dental hygienists) was US$ 75,040 in May 2021, which was greater than the median annual wage for all occupations in the economy of US$ 45,760.

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Introduction

The cell culture technique is present in biological areas for the development of drug discovery, regenerative medicine, and protein production. The cell culture technique has evolved from 2D cell culture to 3D cell culture. The 3D culture resembles physiological conditions closely and has various different advantages over the 2D culture conditions. The 3D cell culture can be defined as the culture of living cells within micro-assembled devices and supports the display of three-dimensional structures mimicking tissue and organ-specific microarchitecture.

The factors driving the market include increasing application of biotech and pharmaceutical companies and hospitals and rise in the patient population affected by cancer. The growing number of patients in need of organ transplantation is propelling the growth of the market. However, the high cost of devices, regulatory framework, and lack of awareness amongst the masses are major challenges for the market.The global market for 3D cell culture is segmented on the basis of technique, product, application, end user, and region. On the basis type of technique, it is segmented into scaffold-based 3D cell culture and scaffold-free 3D cell culture. The scaffold-based 3D cell culture is further segmented into hydrogel-based support and polymeric hard material based support.

The scaffold-free 3D cell culture is further segmented into hanging drop microplates, spheroid microplates containing ultra-low attachment (ULA) coating, and microfluidic 3D cell culture. On the basis of product, it is segmented into consumables and instruments. The consumables are further segmented into culture media, reagents, 3D multi-well plates, and glassware. The instruments are further segmented into bioreactor, flow cytometer, and cell culture chips. On the basis of application, it is segmented into drug discovery, cancer research, stem cell research, tissue screening and engineering, and regenerative medicine. On the basis of end users, it is segmented into pharmaceutical and biotechnology companies, contract research organizations, and research and academic laboratories.

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Key PlayersThermo Fisher Scientific Inc., Lonza, Corning Incorporated, Kuraray Co Ltd, Becton, Dickinson and Company, Merck KGaA, Charles River Laboratories Inc., Tecan Trading AG, ReproCELL Europe Ltd, The Electrospinning Company, Lena Biosciences, Inc., InSphero, Global Cell Solutions Inc., Synthecon, Inc., and 3D Biotek LLC.

Study objectives> To provide a detailed analysis of the market structure along with a forecast of various segments and sub-segments of the global 3D cell culture market> To provide insights into factors influencing and affecting the market growth> To provide historical and forecast revenue of market segments and sub-segments with respect to countries> To provide strategic profiling of key players in the market and comprehensively analyzing their market share, core competencies, and drawing a competitive landscape for the market> To provide economic factors that influence the global 3D cell culture market> To provide a detailed analysis of the value chain and supply chain of the global 3D cell culture market

Target Audience> Research and Development (R&D) Companies> Market Research and Consulting Service Providers> Academic Institutes and Universities> Potential Investors

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Key Findings> The global 3D cell culture market is expected to reach USD 3555.77 million by 2023 at a CAGR of 25.50 %> On the basis of technique, the scaffold-based 3D cell culture is the largest segment which is projected to register a CAGR of 25.81% during the forecast period from 2017 to 2023> On the basis of product, consumables are expected to account for the largest market share of 25.88% during the forecast period from 2017 to 2023> On the basis of application, drug discovery is projected to register a CAGR of 25.75% during the forecast period from 2017 to 2023> On the basis of end user, pharmaceutical and biotechnology companies captured the largest market globally and are expected to reach USD 1398.35 million by 2023> On the basis of region, the market is segmented into the Americas, Europe, Asia-Pacific, and the Middle East and Africa. The Americas holds the largest share of the global 3D cell culture market which is expected to reach USD 1318.73 million by 2023> Asia-Pacific is the fastest growing market, which is expected to register a CAGR of 26.17% from 2017 to 2023

Regional Analysis> Americaso North America? US? Canadao South America> Europeo Germanyo Franceo UKo Italyo Spaino Rest of Europe> Asia-Pacifico Japano Chinao Indiao Republic of Koreao Rest of Asia-Pacific> Middle East & Africao Middle Easto Africa

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Table of Content:

Available Customization

The following customization options are available for this report:> Trends for other verticals including retail travel and hospitality> Country-specific trends and market analysis> Rest of the World (RoW) Region-specific market analysis> Additional company profilesApart from the existing market analysis Reportocean can also offer a wide array of custom-tailored studies as per the companys specific needs.

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3D Cell Culture Market Size 2022 [NEW GROWTH AVENUES] Share, Key Findings, Investment Opportunities, and Forecast till 2030 | Thermo Fisher Scientific...

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Jasper Therapeutics Announces Management Changes to Strengthen Leadership Team – BioSpace

Posted: March 25, 2022 at 1:57 am

REDWOOD CITY, Calif., March 21, 2022 (GLOBE NEWSWIRE) --Jasper Therapeutics, Inc. (NASDAQ: JSPR), a biotechnology company focused on hematopoietic cell transplant therapies, today announced changes to its management team, including the promotions of Jeet Mahal to the newly created position of Chief Operating Officer, and of Wendy Pang, M.D., Ph.D., to Senior Vice President of Research and Translational Medicine. Both promotions are effective as of March 21, 2022. Jasper also announced that a new position of Chief Medical Officer has been created, for which an active search is underway. Judith Shizuru, M.D. PhD, co-founder, and Scientific Advisory Board Chairwoman will lead clinical development activities on an interim basis and Kevin Heller, M.D., EVP of Research and Development, will be transitioning to a consultant role.

Based on the recent progress with JSP191, our anti-CD117 monoclonal antibody, as a targeted non-toxic conditioning agent and our mRNA hematopoietic stem cell program we have decided to advance Jaspers organizational structure with the creation of the roles of Chief Operating Officer and Chief Medical Officer and by elevating our research and translational medicine team to report directly to the CEO, said Ronald Martell, CEO of Jasper Therapeutics. We also are pleased that Dr. Shizuru will lead clinical development activities on an interim basis, a role she served during the companys founding in 2019.

These changes will allow us to advance our upcoming pivotal trial of JSP191 in AML/ MDS and execute on our pipeline opportunities with a best-in-class organization, continued Mr. Martell. We also wish to thank Dr. Heller for his help advancing JSP191 through our initial AML/MDS transplant study.

In the two plus years since we founded Jasper and received our initial funding, the company has been able to advance JSP191 in two clinical studies, develop our mRNA stem cell graft platform and publicly list on NASDAQ, said Dr. Shizuru, co-founder and member of the Board of Directors of Jasper Therapeutics. These changes will strengthen the companys ability to advance the field of hematopoietic stem cell therapies and bring cures to patients with hematologic cancers, autoimmune diseases and debilitating genetic diseases."

Mr. Mahal joined Jasper in 2019 as Chief Finance and Business Officer and has led Finance, Business Development, Marketing and Facilities/ IT since the companys inception. Prior to joining Jasper, he was Vice President, Business Development and Vice President, Strategic Marketing at Portola Pharmaceuticals, where he led the successful execution of multiple business development partnerships for Andexxa, Bevyxxaand cerdulatinib. He also played a key role in the companys equity financings, including its initial public offering and multiple royalty transactions. Earlier in his career, Mr. Mahal was Director, Business and New Product Development, at Johnson & Johnson on the Xareltodevelopment and strategic marketing team. Mr. Mahal holds a BA in Molecular and Cell Biology from U.C. Berkeley, a Masters in Molecular and Cell Biology from the Illinois Institute of Technology, a Masters in Engineering from North Carolina State University and an MBA from Duke University.

Dr. Pang joined Jasper in 2020 and has led early research and development including leading creation of the companys mRNA stem cell graft platform and playing a pivotal role in advancing JSP191 across multiple clinical studies. Previously Dr. Pang was an Instructor in the Division of Blood and Marrow Transplantation at Stanford University and the lead scientist in the preclinical drug development of an anti-CD117 antibody program. She was the lead author on the proof-of-concept studies showing that an anti-CD117 antibody therapy targets disease-initiating human hematopoietic (blood cell-forming) stem cells in myelodysplastic syndrome (MDS). She has authored numerous publications on the characterization of hematopoietic stem and progenitor cell behavior in hematopoieticdiseases, as well as hematopoietic malignancies, including MDS and acute myeloid leukemia (AML), and in hematopoietic stem cell transplantation. Dr. Pang earned her AB and BM in Biology from Harvard University and her MD and PhD in cancer biology from Stanford University.

Dr. Shizuru is a Professor of Medicine (Blood and Marrow Transplantation) and Pediatrics (Stem Cell Transplantation) at StanfordUniversity.She is the clinician-scientist co-founder of Jasper Therapeutics. Dr. Shizuru is an internationally recognized expert on the basic biology of blood stem cell transplantation and the translation of this biology to clinical protocols.Dr Shizuruis a member of the Stanford Blood and Marrow Transplantation (BMT) faculty, the Stanford Immunology Program, and the Institute for Stem Cell Biology and Regenerative Medicine. Shehas been an attending clinicianattendedon the BMT clinical service since 1997.Currently, she oversees a research laboratory focused on understanding the cellular and molecular basis of resistance to engraftment of transplantedallogeneic bone marrow blood stemcells and the way in which bone marrow grafts modify immune responses.Dr. Shizuru earned her BA from Bennington College and her MD and PhD in immunology from Stanford University

About Jasper Therapeutics

Jasper Therapeutics is a biotechnology company focused on the development of novel curative therapies based on the biology of the hematopoietic stem cell. The company is advancing two potentially groundbreaking programs. JSP191, an anti-CD117 monoclonal antibody, is in clinical development as a conditioning agent that clears hematopoietic stem cells from bone marrow in patients undergoing a hematopoietic cell transplantation. It is designed to enable safer and more effective curative allogeneic hematopoietic cell transplants and gene therapies. Jasper is also advancing JSP191 as a potential therapeutic for patients with lower risk Myelodysplastic Syndrome (MDS). Jasper Therapeutics is also advancing its preclinical mRNA hematopoietic stem cell graft platform, which is designed to overcome key limitations of allogeneic and autologous gene-edited stem cell grafts. Both innovative programs have the potential to transform the field and expand hematopoietic stem cell therapy cures to a greater number of patients with life-threatening cancers, genetic diseases and autoimmune diseases than is possible today. For more information, please visit us at jaspertherapeutics.com.

Forward-Looking Statements

Certain statements included in this press release that are not historical facts are forward-looking statements for purposes of the safe harbor provisions under the United States Private Securities Litigation Reform Act of 1995. Forward-looking statements are sometimes accompanied by words such as believe, may, will, estimate, continue, anticipate, intend, expect, should, would,plan,predict,potential,seem,seek,future,outlookandsimilarexpressionsthat predict or indicate future events or trends or that are not statements of historical matters. These forward-looking statements include, but are not limited to, statements regarding the potentialof the Companys JSP191 and mRNA engineered stem cell graft programs. Thesestatementsarebasedonvariousassumptions,whetherornotidentifiedinthispressrelease, and on the current expectations of Jasper and are not predictions of actual performance. These forward-lookingstatementsareprovidedforillustrativepurposesonlyandarenotintendedtoserve as, and must not be relied on by an investor as, a guarantee, an assurance, a prediction or a definitivestatementoffactorprobability.Actualeventsandcircumstancesaredifficultorimpossible to predict and will differ from assumptions. Many actual events and circumstances are beyond the control of Jasper. These forward-looking statements are subject to a number of risks and uncertainties, including general economic, political and business conditions; the risk that the potential product candidates that Jasper develops may not progress through clinical development or receive required regulatory approvals within expected timelines or at all; risks relating to uncertainty regarding the regulatory pathway for Jaspers product candidates; the risk that prior study results may not be replicated; the risk that clinical trials may not confirm any safety, potency or other product characteristics described or assumed in this press release; the risk that Jasper will be unable to successfully market or gain market acceptance of its product candidates; the risk that Jaspers product candidates may not be beneficialtopatientsorsuccessfullycommercialized;patientswillingnesstotrynewtherapiesand the willingness of physicians to prescribe these therapies; the effects of competition on Jaspers business; the risk that third parties on which Jasper depends for laboratory, clinical development, manufacturing and other critical services will fail to perform satisfactorily; the risk thatJaspers business, operations, clinical development plans and timelines, and supply chain could be adversely affected by the effects of health epidemics, including the ongoing COVID-19 pandemic; the risk that Jasper will be unable to obtain and maintain sufficient intellectual property protection foritsinvestigationalproductsorwillinfringetheintellectualpropertyprotectionofothers;andother risks and uncertainties indicated from time to time in Jaspers filings with the SEC. If any of these risksmaterializeorJaspersassumptionsproveincorrect,actualresultscoulddiffermateriallyfrom the results implied by these forward-looking statements. While Jasper may elect to update these forward-lookingstatementsatsomepointinthefuture,Jasperspecificallydisclaimsanyobligation to do so. These forward-looking statements should not be relied upon as representing Jaspers assessmentsofanydatesubsequenttothedateofthispressrelease.Accordingly,unduereliance should not be placed upon the forward-lookingstatements.

Contacts:

John Mullaly (investors)LifeSci Advisors617-429-3548jmullaly@lifesciadvisors.com

Jeet Mahal (investors)Jasper Therapeutics650-549-1403jmahal@jaspertherapeutics.com

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Culture Media Market Outlook, Size, Share and Growth and Forecast Assumptions 2022-2030 – Taiwan News

Posted: March 25, 2022 at 1:57 am

The Culture Media market size was reported at more than $5,000 million in 2020 and is projected to grow at a CAGR of more than 9% during the forecast period from 2021 to 2027.

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A culture medium contains several nutrients that are important for the growth, proliferation, maintenance, and storage of microbes and other types of cells, such as stem cells. Different media types are available on the market for culture to thrive in its incubation environment. In culture media, microorganisms or cells are allowed to grow on solids, liquids, or semi-solids by the process of proliferation. The growth of different types of cells requires different kinds of media. Monoclonal antibodies can be developed with the help of cell culture technology. Laboratory cultures of cells can be used to produce these antibodies synthetically.

Factors Impacting the Culture Media Market

Covid-19 Impact: The Culture Media Market

A public health emergency has been declared by the World Health Organization (WHO) concerning the coronavirus outbreak. About 210 countries around the world have been affected by the Covid-19 virus. Health organizations have faced a huge burden due to the coronavirus pandemic. Many people have either died or remain in hospitals as a result of Covid-19. The human body is to be immunized using vaccines derived from cultures.

Global healthcare systems have been stressed by the coronavirus pandemic. The whole period was marked by instability due to a lockdown in the entire region. To immunize humans, cells are cultivated into vaccines. A rise in demand for vaccines, strict safety rules for novel vaccines, and efforts to minimize and eradicate their spread have led researchers to introduce culture-based vaccines. Researchers and development teams are expected to use cell culture technology to speed up vaccine research. In the media market, the Covid-19 creates a positive impact because it accelerates vaccines.

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Regional Analysis: The Culture Media Market

North America, Europe, Asia Pacific, Middle East & Africa, and South America are the regions where the global cell culture media market is segmented. The market share held by North America is the largest within these segments.

In the global market for cell culture media, North America holds the largest market share. In North America, especially in the United States, cell culture media manufacturers make up the largest portion of the global cell culture media market. Global culture media companies, including Merck KGaA and Thermo Fisher Scientific, manufacture in this area. Therefore, the majority of cell culture products are introduced in the United States before being shipped to other countries. In addition, R&D investments, technological advancements in cell culture media, and high demand for the products will drive the growth of the North American culture media market.

Aim of the Report: the Culture Media Market

The Culture Media Market research report includes specific segments by Type, Application, End-User, and Research Type.

Segmentation based on Type

Segmentation based on Application

Segmentation based on End-User

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Segmentation based on Research Type

Key Players: The Culture Media Market

The Culture Media market includes a variety of well-known companies, including-

What are the key findings of the report?

This report provides comprehensive information on factors expected to influence the market growth and market share in the future.The report offers the current state of the market and future prospects for various geographical regions.This report provides both qualitative and quantitative information about the competitive landscape of the market.

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Culture Media Market Outlook, Size, Share and Growth and Forecast Assumptions 2022-2030 - Taiwan News

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Tissue Banking Market Growth Statistics 2022 Industry Demand, Share Evaluation, Prominent Players Strategies, Size, SWOT Analysis, COVID-19 Impacts,…

Posted: January 20, 2022 at 2:45 am

Report Ocean presents a new report on tissue banking market size, share, growth, industry trends, and forecast 2030, covering various industry elements and growth trends helpful for predicting the markets future.

The global tissue banking market is estimated to witness a CAGR of 11.2% during the forecast period 2018-2024.

Overview: The conservation and banking of tissues subsequent to donor harvest is an extended medicinal area that has until lately witnessed progress. Nevertheless in a similar way we bank stem cells embryos and other tissues at present are likely to govern the biological time for complete tissues through approaches identical to vitrification and controlled hypothermia. The constant growth of tissues and organs scarcity has led to early deaths with consequences in enormous outlays to society. The capacity to bank tissues has an instantaneous effect on transplant medicine surgical treatment of cancer combat trauma and industrial accidents.

The Centers for Medicare and Medicaid Services report that US healthcare expenditures grew by 4.6% to US$ 3.8 trillion in 2019, or US$ 11,582 per person, and accounted for 17.7% of GDP. Also, the federal government accounted for 29.0% of the total health expenditures, followed by households (28.4%). State and local governments accounted for 16.1% of total health care expenditures, while other private revenues accounted for 7.5%.

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This study aims to define market sizes and forecast the values for different segments and countries in the coming eight years. The study aims to include qualitative and quantitative perspectives about the industry within the regions and countries covered in the report. The report also outlines the significant factors, such as driving factors and challenges, that will determine the markets future growth.

Market Analysis: The global tissue banking market is estimated to witness a CAGR of 11.2% during the forecast period 2018-2024. The market is analyzed based on four segments type application tissue type and regions.

Regional Analysis: The regions covered in the report are North America Europe Asia Pacific and Rest of the World (ROW). North America accounts for the largest share of the tissue banking market followed by Europe Asia Pacific and Rest of the World. More than 44.0% of the market is occupied by North America with the US being the major contributor to the market growth.

Type Analysis: Based on types the market is segmented into equipment and consumables. Equipment holds a dominant share in the market and is also the fastest growing segment.

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Application Analysis: Based on application areas the market is segmented into clinical application and research & development. The market is dominated by research & development.

Tissue Type Analysis: Based on tissue banking areas the market is segmented into cardiovascular tissue lung tissue kidney tissue corneal tissue and other tissues. The corneal tissue segment is dominant among others in the market.Key Players: The major players in the market are Thermo Fisher Scientific Danaher Corporation Custom Biogenic Solution Tecan Group and Brooks Automation Inc.

Competitive Analysis: The tissue banking market is facing intense competition due to the presence of many players in the market. However the majority of the market share is occupied by Thermo Fisher Scientific Danaher Corporation Custom Biogenic Solution Tecan Group and Brooks Automation Inc. To maintain their leadership the major players are collaborating with small players who have advanced technology. For instance in March 2014 Brooks Automation collaborated with BioCision for the development of automated temperature-controlled technology for biobanking and sample handling. This association helped in filling the gap amongst sample handling and automation process.

Benefits: The report provides complete details about the usage and adoption rate of tissue banking in various regions. With that key stakeholders can know about the major trends drivers investments and vertical players initiatives. Moreover the report provides details about the major challenges that are going to impact on the market growth. Additionally the report gives the complete details about the key business opportunities to key stakeholders to expand their business and capture the revenue in specific verticals to analyze before investing or expanding the business in this market.

Key Stakeholders:

Region/Country Cover in the Report

North America Europe Asia Pacific and Rest of the World (ROW)

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Key Players Covered in the Report

Thermo Fisher Scientific Danaher Corporation Custom Biogenic Solution Tecan Group and Brooks Automation Inc

What are the aspects of this report that relate to regional analysis?

The reports geographical regions include North America, Europe, Asia Pacific, Latin America, the Middle East, and Africa. The report provides a comprehensive analysis of market trends, including information on usage and consumption at the regional level. Reports on the market include the growth rates of each region, which includes their countries, over the coming years. How are the key players in the market assessed? This report provides a comprehensive analysis of leading competitors in the market. The report includes information about the key vendors in the market. The report provides a complete overview of each company, including its profile, revenue generation, cost of goods, and products manufactured. The report presents the facts and figures about market competitors, alongside the viewpoints of leading market players. A market report includes details on recent market developments, mergers, and acquisitions involving the key players mentioned.

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Tissue Banking Market Growth Statistics 2022 Industry Demand, Share Evaluation, Prominent Players Strategies, Size, SWOT Analysis, COVID-19 Impacts,...

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Researchers develop fast COVID-19 test using atom-thick sheets of graphene – FierceBiotech

Posted: June 23, 2021 at 2:22 am

Researchers at the University of Illinois Chicago have potentially found a new method of passively detecting the coronavirus using sheets of graphene, one of the thinnest and strongest materials on the planet.

Their premise is rather straightforward: First, the researchers studded the graphene surface with antibodies designed to bind to the coronaviruss spike protein. Whenever they connect, strong molecular vibrations ripple through the sheet, delivering a COVID-19 signal to a super-sensitive motion detector in less than five minutes.

We have been developing graphene sensors for many years. In the past, we have built detectors for cancer cells and ALS, said Vikas Berry, Ph.D., professor and head of chemical engineering at the UIC College of Engineering and senior author of the paper published in the journal ACS Nano. It is hard to imagine a more pressing application than to help stem the spread of the current pandemic.

RELATED: NIH awards $107M for 'radical' COVID-19 testing tech aimed at everyday life

The researchers tested their graphene sheetsa Nobel Prize-winning material made of a single layer of carbon molecules and more than 1,000 times thinner than a piece of paperwith artificial saliva samples both positive and negative for COVID-19 as well as other coronaviruses such as the bug behind Middle East respiratory syndrome, or MERS.

The changes in the graphenes vibrations in the presence of COVID-19, optically measured by a Raman spectrometer, proved to be fast, accurate and relatively cheap to collect, minus the cost of the sensor itself.

RELATED: Graphene-based sensor could help ward off asthma attacks

Graphene is just one atom thick, so a molecule on its surface is relatively enormous and can produce a specific change in its electronic energy, Berry said in a statement.

With its unique properties, the researchers say graphene could provide a platform that can be tuned to other COVID variants as well as other diagnostic applications.

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