Category Archives: Hormone Replacement Therapy

The Brainy Insights aims to increase firms business acumen by giving functional and actionable insights with valuable data in Global Hormone Replacement Therapy Market. To satisfy the clients objectives of high-quality customized output in a short period, the organization has a robust collection, analytical, interpretational, and forecasting methodology for information extraction. The data analysis methods facilitate the synthesis of raw data into information utilized for factual analysis resulting in better decision-making.

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Quantitative analysis is based on historical and forecast years, with 2021 as the base year. Exhaustive methodologies gather the forecasted data from global and regional markets. The interpretation and analysis of raw data are performed in line with the buyers objectives. The holistic interpretation according to clients requirements will answer the most crucial market questions that are important in business decision-making.

The different qualitative tools used in the Hormone Replacement Therapy market include PESTEL analysis, PORTERS five forces, and SWOT analysis, for determining various attributes such as the opportunities and threats of new market entrants in the industry, the pricing and bargaining power of the buyers and the sellers, availability of substitute goods or services, and the market penetration of already established sellers in the market and the presence of suppliers and vendors.

Key Components of the Hormone Replacement Therapy Market

The report consists of a segmentation analysis, regional analysis, and company profiling section. The operating segments of the Hormone Replacement Therapy market are as follows:

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The global market has been segmented into the following regions, witnessing high demand and the presence of key players. These locations include: North America (United States, Canada & Mexico)

Asia-Pacific (Japan, China, India, Southeast Asian Countries & Australia etc)

Europe (Germany, UK, France, Italy, Spain, Russia, Netherlands & Belgium etc)

Central & South America (Brazil, Argentina, LATAM etc)

Middle East & Africa (United Arab Emirates, Qatar, Saudi Arabia, Israel & South Africa etc)

All prominent participants in the Hormone Replacement Therapy market are investigated, and their business models and revenue segmentation are evaluated. The key vendors profiled in the Hormone Replacement Therapy market include Abbott Laboratories, Novartis, Pfizer, Inc., Mylan Laboratories, Merck and Co., Novo Nordisk, Bayer Healthcare, Eli Lilly, Genentech

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The Brainy Insights is a market research company, aimed at providing actionable insights through data analytics to companies to improve their business acumen. We have a robust forecasting and estimation model to meet the clients objectives of high-quality output within a short span of time. We provide both customized (clients specific) and syndicate reports. Our repository of syndicate reports is diverse across all the categories and sub-categories across domains. Our customized solutions are tailored to meet the clients requirement whether they are looking to expand or planning to launch a new product in the global market.

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Phone: +1-315-215-1633

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Global Hormone Replacement Therapy Masks Market 2022 Growth, Share, Trend, Segmentation and Forecast to 2028 themobility.club - themobility.club

On this pageWhat is MHT/HRT?

Menopausal hormonal therapy (MHT), formerly called hormone replacement therapy (HRT), is when hormones are used to treat the symptoms of menopause, especially hot flushes and night sweats. There are benefits and risks with MHT, so it is important to talk to your doctor if you are considering it.

The main types of MHT are based on hormones, such as oestrogen, progesterone and testosterone, that occur naturally in the body.

During menopause, hormone levels go up and down, resulting in symptoms such as hot flushes and night sweats.

MHT helps restore hormone levels, which may improve some menopause symptoms.

The main hormone used in MHT is oestrogen. In women who have not had a hysterectomy, progesterone needs to be taken at the same time to reduce the risk of endometrial cancer.

Some women benefit from a low-dose testosterone replacement to improve low libido, lack of energy and fatigue.

Other forms of MHT are Tibolone or Duavive tablets.

MHT can be taken as:

MHT/HRT is usually helpful if you experience problems with hot flushes and night sweats. Mood, sleep and sex drive problems may also improve. Some women also say they find improvements in joint aches, vaginal dryness and incontinence.

The main risk is that some types of MHT lead to a slightly increased risk of developing breast cancer or thrombosis (blood clots in the legs or lungs). However, it can prevent other conditions such as osteoporosis, heart disease, fractures, diabetes and some types of cancers.

Current international recommendations say that the benefits outweigh the risks in women who are having significant symptoms from menopause, and that MHT is effective and safe for most healthy women.

Some women have side effects such as nausea, fluid retention, bloating, breast tenderness and swelling, and irregular bleeding. These often go away with time.

MHT may not be suitable for you if you have or have had:

The risks of MHT depend on your age, the type and dose of hormone therapy you take, duration of treatment, and your medical history.

Talk to your doctor to find out which risks apply to you. If you are unable to take MHT, your doctor may suggest other medications that may be helpful.

You can minimise the risks associated with MHT by:

If you are interested in taking MHT, please talk to your doctor to see if it is right for you.

Continue reading here:
Hormone replacement therapy (HRT) | healthdirect

The Brainy Insights recently added Market Research Study for Hormone Replacement Therapy Market aiming at market size breakdown by key segments, application and companies to better define changing market dynamics and structure. The study explains a detailed overview on growth drivers, influencing trends, targeted geographies, product/service portfolio, business models, and the latest industry development shaping market.

Know why your competitors approach in Hormone Replacement Therapy Market is different?

Abbott Laboratories, Novartis, Pfizer, Inc., Mylan Laboratories, Merck and Co., Novo Nordisk, Bayer Healthcare, Eli Lilly, Genentechare some of the major and emerging companies operating in the market. Check what market leaders are involved in either partnerships, agreement or merger & acquisition to gain an edge over their competitors, furthermore why emerging players are adopting various business strategies to build technological advancement in Global Hormone Replacement Therapy Market.

Hormone Replacement Therapy Market, by Region: Americas, United States, Canada, Mexico, Brazil, APAC, China, Japan, Korea, Southeast Asia, India, Australia, Europe, Germany, France, UK, Italy, Russia, Middle East & Africa, Egypt, South Africa, Israel, Turkey & GCC Countries

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Customers May Help Identify Market Gaps

Additionally, study precisely covers and examine survey analysis by end users along with primary respondents from Industry to assess market evaluation. The qualitative commentary on changing market dynamics of Hormone Replacement Therapy and consumer behavior and purchasing patterns helps identify real market gaps. This survey of Adroit Market Research took a holistic view of consumer behaviors and market perceptions from the start of the pandemic and throughout. For Consumer Centric Market, Survey or Demand Side Analysis customization is provided wherever applicable which consider Buying behavior, demographic factor such as Age, Gender, Occupation, Income Level or Education while gathering data. (if applicable)

Global Hormone Replacement Therapy Market: Segmentation / Scope

Hormone Replacement Therapy Market, by Type:

Hormone Replacement Therapy Market, by Application:

Assess Your Strengths & Weakness: To Open & Size New Opportunities

The in-depth competition landscape and company profile helps you correlate business strategies, key development activities, and recent innovation in features of products/services offering. It is always useful to assess our weakness and strength to have competitive edge henceforth SWOT analysis along with company financials metrics that includes operating efficiency, net profit margin, turnover cycle along with products/services specification and sales offices and footprints to provides a deep assessment in identifying gaps and opportunities to make the companys marketing strategy cost-effective for business.

Identify Opportunities for Hormone Replacement Therapy Market Growth

In this crowded, fast-moving landscape, marketing teams have to create big impact with less information to work with. With countless industry related announcements made every day, it becomes noteworthy to get real insights out of it. Under normal circumstances, to check pulse on your product/services and identify new opportunities; market survey released by Adroit Market Research may get you desired results.

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Extracts from Table of Content

Thanks for reading this article; you can also get individual chapter wise section or region wise report version like Complete America, LATAM, Europe, Nordic regions, Oceania or Southeast Asia or Just Eastern Asia.

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The Brainy Insights is a market research company, aimed at providing actionable insights through data analytics to companies to improve their business acumen. We have a robust forecasting and estimation model to meet the clients objectives of high-quality output within a short span of time. We provide both customized (clients specific) and syndicate reports. Our repository of syndicate reports is diverse across all the categories and sub-categories across domains. Our customized solutions are tailored to meet the clients requirement whether they are looking to expand or planning to launch a new product in the global market.

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Global Hormone Replacement Therapy Market 2022 Key Trends, Competitor Analysis and Research Report by 2028 Bloomingprairieonline -...

How does menopause affect the bones?What is the menopause?

Menopause is the time in a womans life when the ovaries stop producing enough hormones for pregnancy. Around the menopause, the level of oestrogen can vary for a time and then eventually decreases. This often causes symptoms such as hot flushes and sweats.

You've completed your menopause (or are post-menopausal) when you havent had a period for at least one year. The average age for this to happen is 51 years.

Some women have an early menopause, before the age of 45. This can happen naturally, or after surgery to remove your ovaries. Early menopause can also be triggered by chemotherapy or radiotherapy, as these treatments can cause a sudden drop in hormones.

The inside of our bones is constantly being broken down and rebuilt by specialist bone cells. This process, called bone remodelling, helps to keep bones healthy and strong.

During the menopause, the drop in oestrogen causes this process to become out of balance. More bone is broken down than formed, leading to bone loss.

Bone loss happens more quickly for a few years around the menopause. You then continue to lose bone at a slower rate as you get older. Over time, you may develop osteoporosis and a higher risk of breaking bones in later life. This is particularly likely if you have an early menopause.

HRT is medication that mimics oestrogen and progesterone.

HRT usually combines both hormones. This is because oestrogen taken on its own could make your womb lining too thick and increase your risk of womb cancer. But if youve had surgery to remove your womb (a hysterectomy), youll only need to take oestrogen.

There are more than 50 different HRT products available for prescription in the UK, including tablets, patches that you stick on your skin, small implants that are placed under the skin, and gels you rub on your skin. Progestogen is also available via a contraceptive device called a coil.

There are also rings, creams and pessaries (small removable devices) that can be placed inside the vagina to treat symptoms such as vaginal dryness. But these aren't used to treat osteoporosis, as they only contain very low levels of oestrogen.

HRT comes in the following three forms. Your healthcare professional should explain which form is most suitable for you and why.

Sequential combined therapyYou take oestrogen every day and progestogen for around 12 days per month. The progestogen causes you to have a bleed like a menstrual period.

Continuous combined therapyYou have both oestrogen and progestogen every day, so you wont have periods. The progestogen stops your womb lining from getting too thick. You need to be at least a year past your last period before having continuous combined therapy, or it may cause irregular bleeding.

Oestrogen-only HRTThis doesnt contain any progestogen. You can have oestrogen-only HRT if youve had an operation to remove your womb (a hysterectomy). You wont have any periods.

Tibolone (Livial)This is taken as a tablet once a day. Its similar to taking combined HRT, but contains the ingredient tibolone, rather than oestrogen and progestogen. Tibolone mimics oestrogen, progesterone, and the hormone testosterone inside the body. It can be used if you completed your menopause over a year ago. It may be helpful for libido (desire for sex) and bone strength.

Regulated bio-identical hormonesThese medications are designed to be more similar to the hormones we produce naturally. They include:

Some clinicians prescribe these with oestrogen, instead of standard progestogen, as they are less likely to cause side effects or increase risks of blood clots and stroke. They may also be less likely to increase the risk of breast cancer. There isnt as much research about these newer products, which is why most doctors still prescribe standard progestogen.

Natural bio-identical hormonesThese unregulated products are different to the regulated bio-identical hormones mentioned above. They havent been tested in the same way to prove they work and are safe. Its important to remember that just because a product says it is natural, this doesnt automatically mean it is safe or effective.

Visit the Womens Health Concern website for more information about all of these treatments.

HRT causes your oestrogen levels to increase. This can help to prevent bone loss and reduce your risk of developing osteoporosis and of breaking bones.

If you already have osteoporosis or a high risk of breaking bones, HRT can help to strengthen your bones and make fractures less likely.

Is it as effective as other osteoporosis drugs?

There havent been many studies comparing HRT with other osteoporosis drug treatments. But its thought that HRT probably reduces the risk of breaking a bone by a similar amount to other osteoporosis medications, including bisphosphonates.

As with all medications, HRT has both benefits and risks.

The levels of risk vary from one person to another and depend on things such as your age, weight, medical and family history. As you reach your 60s, the overall risks of HRT may outweigh the benefits. This is because your risk of the health problems mentioned above increases naturally with age, and taking HRT could add to this risk.

Its important to discuss your own benefits and risks with your doctor, so you can decide whats right for you. A regular review of treatment choices is also useful.

Worried by stories you've seen in the news?

You may have seen news stories about HRT, and be feeling worried and confused about its safety. But it's important to remember that news stories arent always accurate or balanced.

Experts regularly review the safety and use of treatments. If official guidance on HRT changes, well update our information on this website. You can also find reliable, up-to-date information on the NHS website, or on other websites such as Womens Health Concern and Menopause Matters.

As with any drug, HRT can cause side effects. But most people dont get any side effects and they dont usually last for long. Possible side effects include:

The patient information leaflet that comes with your treatment will have more information on possible side effects of HRT.

If you do get side effects that don't go away, speak to your doctor or pharmacist.

Its very important to consider taking HRT if you reach menopause early. This is because you will start losing bone at an earlier age than the average woman, increasing your risk of osteoporosis and broken bones. If youve had an early menopause, talk to your healthcare professional about taking HRT, at least until you are about 50.

Many women take HRT to treat symptoms caused by the menopause. Even if this is your main reason for taking HRT, you can be reassured that youll also be helping your bones.

HRT is also an option after the menopause as an osteoporosis drug treatment. Its particularly helpful for women needing a bone-strengthening medication who also have menopausal symptoms.

The decision about which osteoporosis treatment to use will depend on lots of things, including your own level of fracture risk, whether youve already broken a number of bones, your age, and your own needs and preferences. Youll need to speak with your healthcare professional about the most suitable treatment for you.

Like any osteoporosis medication, HRT wont reduce the pain caused by broken bones. But dont worry there are other medications and treatments for pain that can help.

Make sure it's the right treatment for youGet all the information you need and discuss any questions or concerns with your doctor. For many women, HRT will be a useful option. But it may not be right for you if youve previously had a blood clot, breast, ovarian or womb cancer, heart disease, untreated high blood pressure, or liver disease.

Its important to read the information in the patient information leaflet that comes with your treatment. You can also read more detailed information in our fact sheet, 'Hormone replacement therapy (HRT) and bone health'.

Ourspecialist nurse Helplineis here for you, if you have any questions or concerns. Call free on 0808 800 0035.

Make sure you understand your dose, monitoring regime, and what happens nextHRT as a tablet, patch or gel will usually help with bone strength, even if youre having a low dose such as 1mg oestradiol. But you may need a higher dose, such as 2mg, if your menopausal symptoms are severe or arent improving.

You wont need regular blood tests to check your oestrogen levels while youre taking HRT. You probably wont need regular bone density scans either, even if youre taking HRT to help strengthen your bones. However, your healthcare professional may recommend regular scans if you have a high risk of breaking bones.

You should have a medication review about once a year, to make sure HRT is still the right choice for you. Make sure you mention any side effects youre getting. Its important to understand the possible side effects and ways to reduce them.

You can keep taking HRT as long as the benefits outweigh any risks. Some women stay on HRT for several years. How long you take it for will depend on your own situation talk to your doctor about this.

When you stop taking HRT, the beneficial effect on your bones will begin to decrease straight away. If you still have an increased risk of breaking a bone, your doctor will probably recommend you start a different type of osteoporosis drug treatment. Or they may suggest you have a bone density scan or other tests.

Lead a healthy lifestyleIt's important to follow the usual guidance on healthy living while you're on HRT, and aim for a calcium intake of around 1,000mg a day. Your doctor may prescribe calcium and vitamin D supplementsif you cant get enough from your diet.

Content reviewed: February 2022

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Hormone replacement therapy - Royal Osteoporosis Society

Menopause and rheumatoid arthritis may share a connection related to hormones. However, experts dont fully understand or agree on the link.

Menopause occurs when a person doesnt have their period for 12 consecutive months for no other reason. It naturally occurs around the age of 50, though it can occur earlier or later based on the person.

Some studies and anecdotal evidence suggest that when a person goes through menopause, their RA symptoms get worse.

However, a 2020 study has shown that female reproductive hormones play no role in the development or severity of RA. They also noted that previous studies showed hormones had a protective effect, negative effect, or no effect at all.

Previous studies have shown a connection may exist between menopause and RA. The problem is that the studies havent agreed on exactly how or even if menopause has any effect on RA.

In a 2017 review of studies, researchers also noted that the effects of menopause on RA couldnt be determined. The review noted some of the discrepancies across studies including the following:

Still, a report published in 2018 indicated that menopause can cause additional or worsening symptoms in people living with RA. The study authors said that hormones may play a protective role in RA but also noted that additional research is needed to fully show or understand the connection.

Another study published in 2017 also noted that several hormone factors in women, including early onset and postmenopause onset, play a role in RA development and worsening. However, like other studies, they noted that additional research is needed to fully show and prove the connection between female hormones and RA.

You can take steps to manage the symptoms of both menopause and RA. For some people, treatments that help with menopause may also help with RA symptoms, but this isnt necessarily always the case.

Treatments for menopause often include one or more of the following:

You may find that certain supplements, such as soy, may help with menopause symptoms. You may also benefit from body and mind practices such as yoga, acupuncture, and meditation.

Some other steps you can take to manage menopause symptoms and risks can include:

Some suggestions for managing RA are similar to managing menopause. Some home-based care you can try include:

Some evidence suggests that hormone therapy may have an effect on both menopause and RA, while other evidence suggests not.

According to a 2017 review, studies have shown both positive and negative effects of hormone replacement therapy on RA symptoms. They indicate that more evidence is needed to make any conclusions regarding this treatment option and how it relates to RA.

You should talk with your doctor before making any major changes to your RA treatment routine, such as stopping or increasing the use of medication.

Also, you should talk with your doctor before adding a supplement to your diet to make sure it does not interfere with your current treatments.

You may also want to consider talking with your doctor if your RA or menopause symptoms become worse. They may be able to recommend additional therapies, make changes to current treatments, or make other recommendations.

RA and menopause may share a common connection due to the possible interaction between RA and hormones.

At this time, data isnt sufficient enough to show whether hormones and menopause have a negative effect, a protective effect, or no effect at all.

If you find your symptoms of RA getting worse during menopause, you should talk with your doctor to let them know what is going on. They may be able to suggest changes to your treatment.

You can also take steps at home, including getting regular exercise, eating a balanced diet, practicing good sleep hygiene, and using supplements to help improve your symptoms.

Originally posted here:
Menopause and Rheumatoid Arthritis: What to Know - Healthline

Hot flashes are common, long-term symptoms associated with menopause.

While hot flashes can be uncomfortable and disruptive for many people, they may also come with an unexpected link: a reduced risk of breast cancer.

In this article, we discuss what the latest research says about the possible link between hot flashes and a lower risk of breast cancer. We also take a look at options for treating hot flashes.

Hot flashes develop when estrogen and progesterone levels begin to change before and during menopause. Its thought that these hormonal fluctuations may disrupt the thermoregulatory center in your brain, leading to changes in heat production.

While hot flashes increase in frequency during the 2 years after you start menopause, they can last for 7 to 11 years or longer.

One 2016 review revealed an increase in breast cancer risk in those who had higher estrogen levels. Additionally, researchers found up to a 50 percent reduction in breast cancer risk in people who experienced menopausal vasomotor symptoms (VMS) like hot flashes and night sweats.

Also, a 2018 study of postmenopausal women with persistent VMS found a higher risk of breast cancer diagnosis but a reduced risk of related death. This may suggest a longer presence of hormones influencing the subsequent development of breast cancer.

While more clinical research is needed to determine whether hot flashes could provide a concrete indicator of a reduced breast cancer risk, such menopausal symptoms do indicate a decrease in lifetime exposure to the hormones (estrogen and progesterone) that may be associated with this cancer.

Its also important to note that researchers have found VMS in individuals post-breast cancer diagnosis. In such cases, the onset of VMS may also be attributed to tamoxifen, a type of estrogen modulator used in breast cancer treatment.

While hot flashes may be associated with a lower risk of breast cancer, there are still treatment options if you want to reduce their occurrence.

If youre interested in treatment for hot flashes, your doctor will likely recommend nonhormonal methods first. These may include:

In some cases, hormone replacement therapy (HRT) may be recommended if your hot flashes and other symptoms of menopause significantly impact your overall quality of life.

However, HRT isnt appropriate for everyone. It may increase your risk of developing breast cancer as well as the following:

If your doctor does recommend HRT, theyll likely start with the lowest, most effective dose. Its important to discuss all of the potential risks versus the benefits with your doctor.

In addition to medical treatments, you can ask your doctor about certain complementary therapies for hot flashes. These include:

While some herbal remedies and phytoestrogens are marketed to people experiencing hot flashes, its important to discuss these with your doctor before using them.

Herbs and supplements may potentially interact with medications you take, and theres a lack of clinical evidence supporting their efficacy. Additionally, some herbal remedies may cause liver damage.

To help manage hot flashes, you can also:

While the development of breast cancer depends on a variety of factors, the risk of receiving a breast cancer diagnosis may be higher if you:

Some lifestyle factors that may also increase your risk of developing breast cancer include the following:

Other possible, but not yet proven, risk factors for breast cancer may include:

Hot flashes occur before, during, and after menopause as estrogen and progesterone hormones start declining.

While the exact relationship still requires further clinical research, some studies have revealed a link between hot flashes and a reduced risk of developing breast cancer.

Hot flashes alone dont decrease the risk of breast cancer developing, but they may indicate a lowered lifetime exposure to hormones that do contribute to cancer risk.

In the meantime, if youre currently experiencing hot flashes, you may consider talking with a doctor about treatment options that could help you find relief without contributing to your overall breast cancer risk.

Its also important to understand your own personal breast cancer risks to help reduce the chances of its development.

See original here:
Hot Flashes and Breast Cancer Risk: What the Research Shows - Healthline

In 2017, the British Government Equalities Office reported that significant numbers of working women experience problems at work as a result of individual symptoms ... The evidence also paints a consistent picture of women in transition feeling those around them at work are unsympathetic or treat them badly, because of gendered ageism.

The U.K. has approximately 4 million employed women between 45 and 55, accounting for more than 25% of all women in the workforcethe largest cohort. So, you might think that this sort of affliction in the workplace might be protected by law. It is, after all, both an occupational health and equality issue.

But menopause is sadly not covered by the 2010 Equalities Act, which deals with protected characteristics in the workplace (among other things). What is covered: pregnancy and maternity, race, religion, sexual orientation, gender reassignment, marriage/civil partnership, sex, age and disability. You could argue that menopause is covered by age, sex and disability, but its discomforting for it to be so vagueand its why there is a huge push to get menopause formally categorized.

A couple of years ago, I started experiencing menopausal symptoms. It was insidious and gradual but became increasingly problematic to keep hidden. I felt that I needed to understand moreabout the symptoms, the biology and why there is such a stigma. More importantly, I felt I needed to talk about it, for my own sanity and also because the stigma will fade only if talking about menopause becomes as normal as talking about pregnancy.

However, thats easier said than done.

Male supervisors are often uncomfortable talking about womens issues, and women are reluctant to reveal any inadequacy for fear of judgement or retribution. As Brits, we are disciplined, self-controlled and unemotional, stoical and stiff upper-lipped. Theres a crisis, just pop the kettle on. We keep smiling and waving, or, at the very least, only slightly awkwardly staring into the middle distance.

But this pointless taboo can be addressed only by acknowledging such behavior is not a badge of honor; its repressed, regressive and damaging to business. If leaders truly want to lead, they need to create open and inclusive working environments that offer care and support to their staff. And if they want to retain talented, experienced and dynamic women, they not only need to have menopause on the radarthey need to have it in the spotlight.

Developing strong menopause policies and robust support strategies isnt just good emotional quotient, its good business sense. It will create better workplaces for everyonemale, female or non-binaryaffected by the change. It will help the gender pay gap, it will help diversity and it will help business.

Here are some ways to begin the shift in mindset:

Start by publicly recognizing the challenges that menopausal women face and develop strategies about how they can be supported. Its important for women to feel that they dont need to hide their symptoms, and that any discussions will be met with empathy and support.

There doesnt need to be loads of research and soul-searching. Both Channel 4 and Dark Horses made menopause policies public for anyone to use, adapt and improve. Make sure the policy is for everyone, not just for women, as employees of all ages and genders need to understand more about it, as they will inevitably come across menopausal womenas colleagues, clients, suppliers, friends and family. But a policy on its own is not enough.

Ensure that line managers understand their role in delivering good working practices. They need to be prepared to make accommodations and aware of the easy adjustments and small tweaks that can make a significant difference. These include a safe environment to bring up any challenges their staff are facinghow long they can concentrate, what impact physical symptoms might have on them. Its good to be able to agree some basics, so there is no guilt or feelings of underdelivery, including working from home/flexible working, condensed or shorter hours, desk fans, cameras off and so on.

Hold a menopause workshop; there are plenty of great organizations that dont cost a fortune and make it an engaging and interactive experience. Appoint a menopause champion. Commit to paying for hormone replacement therapy treatment for staff.

Menopause symptoms are wide and varied and sometimes challenging to cope with. But structured support and good management can make a huge difference. Lets really try to stop losing women each year to this. Lets change the change.

Dont miss the latest news. Sign up for Ad Age newsletters here.

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How to remove the stigma of menopause in the workplace - AdAge.com

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As the creator of Black Girl's Guide to Surviving Menopause podcast and social media project, Omisade Burney-Scott, 55, has two missions. The first is to normalize menopause, a natural event that will happen to more than half of the population yet still remains shrouded in silence. The second: to center the voices of Black women and gender-expansive individuals, who experience many of the same symptoms that white women dohot flashes, insomnia, joint painbut often do so in a very different (and usually more intense) way.

Hers is an enormous undertaking, with 50 million+ U.S. women, women-identifying people, and nonbinary people currently in menopausedefined as the end of ones menstrual cyclesand millions more in perimenopause, the four to 10 years leading up to it. More than a third of these are women of color, yet this universal hormonal phenomenon is rarely discussed within their communities, and the experiences and stories of Black and Latinx women are rarely centered in the media or by physicians, according to Denise Pines, Immediate Past President of the Medical Board of California and founder of WisePause Wellness, a pro-aging platform.

When we read about menopause, we think of white womens menopause [experiences] because those are the stories that get told, Pines says. But while our biology may be the same, our experiences are not. Black and Latinx women enter menopause earlier and have longer-lasting, more intense symptoms. Hispanic women are more likely to report feeling bothered by vaginal dryness, urine leakage, and increased heart rate, whereas Black women frequently cite hot flashes and night sweats, according to the Study of Womens Health Across the Nation (SWAN), a decades-long study examining the health of midlife women across ethnicities.

Burney-Scott notes that news reports will often briefly mention the fact that Black and Latinx women have longer and more intense symptoms of menopause but then there is a hard stop. What about the why?

The average age of menopause in the U.S. is 51. SWAN findings reveal that Black women tend to begin menopause about nine months earlier than white women. Other SWAN findings show that Black and Hispanic women endure hot flashes for several years longer than other racial and ethnic groups (10 years and nine years, respectively, versus 6.5 for non-Hispanic white women) and Black women experience irregular bleeding for longer periods of time than white women.

Michelle A. Albert, MD, MPH, professor of medicine at the University of California at San Francisco, president-elect of the American Heart Association, and president of the Association of Black Cardiologists, says this phenomenon, called early-onset menopause, triggers a cascade of events leading to worsened health outcomes for BIPOC women. Cardioprotective estrogen plummets during menopause, meaning all women, regardless of race or ethnicity, experience an increase in heart disease and stroke risk during and after the menopausal transition, but the earlier the age of menopause, the greater the risk. Female hormones also help to protect you from obesity and insomnia, as well as keep cholesterol levels down, and those are all factors associated with elevated heart disease risk, too, Albert says. Additionally, early-onset menopause ups the risk of osteoporosis (estrogen helps keep bones strong) and depression.

Black women are also three times more likely to experience premature menopausemenopause before age 40, sometimes caused by smoking or autoimmune conditions such as lupus or rheumatoid arthritiscompared with white women, leading to a 40 percent higher risk of developing coronary heart disease over their lifetime, per research presented at a 2021 American Heart Association (AHA) meeting.

A 2022 SWAN study published in Womens Midlife Health proposes that some of the disparities that exist between white women and women of color in perimenopause and menopause are likely attributable to structural racism in the U.S. This link has yet to be definitively proven, notes study coauthor and SWAN investigator Ten T. Lewis, PhD, associate professor of epidemiology at Emory Universitys Rollins School of Public Health in Atlanta, but we know that stress matters.

Explains Albert, Its called allostatic load, which refers to the wear-and-tear from lifetime and ongoing stressors that Black women disproportionately face compared with white women. Systemic racism, including poor access to healthcare, toxic work environments, unsafe neighborhoods, socioeconomic challenges, and more, can weather the body, over-taxing various hormonal and biological processes and fueling chronic inflammation. This can lead to long-lasting health ramifications, including an earlier, more challenging menopause.

Despite the fact that Black women enter menopause earlier, and the symptoms last longer, they are the least likely to leave the office with a prescription for hormone treatment, says Sharon Malone, MD, Washington, D.C.based ob-gyn and chief medical officer of Alloy Womens Health. This may have to do with the common but erroneous belief that Black people have a higher pain tolerance, suggest some experts. Women of color often go to the doctor and the doctor says, Oh, no, youre too young [for menopause], Pines says, or they want you to grind it out, and women walk away with nothing. Or they assume patients cant afford hormone replacement therapy or other solutions. This goes beyond a comfort issue: Symptoms like hot flashes and weight gain can be linked to future heart disease, diabetes, and other serious conditions that are already more prevalent among Black and Latinx women.

Several of the experts interviewed for this story said there are concrete steps BIPOC women can take to help flip the script and improve the odds of an easier, healthier menopausal transition.

Malone notes there are plenty of positives accompanying this time of life in general. For a lot of women, its the first time they get to focus on themselves. Youve been concerned about your children, your job, the lens through which people view you, and trying to live up to those expectations. You get to 55, and its freeing.

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If You're a Woman of Color, Here's What to Know About Menopause - Oprah Mag

ROBERT WOOD JOHNSON UNIVERSITY HOSPITAL SOMERSET ADDS BEHAVIORAL HEALTH THERAPIST DEDICATED FOR MEMBERS OF LGBTQ+ COMMUNITY

SOMERVILLE, NJ, April 13, 2022 Patients at the Babs Siperstein PROUD Center at Robert Wood Johnson University Hospital (RWJUH) Somerset, an RWJBarnabas Health facility, now have access to behavioral health services with a therapist dedicated to working with members of the LGBTQ+ community.

Kim Keyes, LCSW, an outpatient behavioral health therapist, has 18 years of experience as a social worker helping children and families. Keyes is available five days a week for in-person and telehealth appointments.

Ive always had a special interest in working with the LGBTQ+ community but recently decided to become more professionally involved as I have a close family member who identifies as transgender, she says. Im here to help support members of the LGBTQ+ community throughout their journey, from exploring gender identity or sexual orientation to coming out to their friends and family and learning to live fully as their true selves, which may include developing coping skills or ways to build their personal support network. This is a safe space where they can find understanding and acceptance and develop a plan to address the unique challenges they face.

Lesbian, gay and bisexual adults are twice as likely as heterosexual adults to experience mental health conditions and transgender individuals are four times as likely as cisgender individuals to experience a mental health condition, according to the National Alliance on Mental Illness. Depression, anxiety and suicide rates are also higher in the LGBTQ+ community. About 40 percent of transgender adults have attempted suicide in their lifetimes.

Coping with stigma, prejudice and discrimination can contribute to higher incidences of mental health issues among the LGBTQ+ community, Keyes says.

The transitioning process can be very stressful for transgender individuals. They are worried about how to tell others and what their reaction will be as well as anxious about starting hormone replacement therapy and considering surgical options, she says. Talking it through with someone who is supportive helps them develop healthy coping skills.

Too many members of the LGBTQ+ community suffer in silence. We are excited to be able to offer our patients convenient access to behavioral health services right here on our campus, said Perry Farhat, Esq., director of diversity and inclusion at RWJUH Somerset and director of the Babs Siperstein PROUD Center. Mental health is a key part of patients overall health and wellness.

RWJUH Somerset has been nationally recognized for providing culturally competent care and reducing health care disparities. The Human Rights Campaign has honored the hospital as a Leader in LGBTQ+ Healthcare Equality seven years in a row.

RWJUH Somerset was the first hospital in New Jersey to offer specialized primary care services for the LGBTQ+ community. The Babs Siperstein PROUD Center, which celebrates its fifth anniversary this year, offers hormone therapy and monitoring, HIV care, health education, counseling, support groups and referrals for specialty services.

Most major insurance plans are accepted. Costs for behavioral health services for uninsured LGBTQ+ patients will be covered through funding from a grant from TD Bank.

About RWJ University Hospital Somerset

Robert Wood Johnson University Hospital Somerset is a nationally accredited, 341-bed hospital in Somerville, New Jersey, providing comprehensive emergency, medical/surgical and rehabilitative services.

The hospital is nationally recognized as a Magnet hospital for nursing excellence and has earned an A Hospital Safety Score from Leapfrog its highest patient safety rating.

The Steeplechase Cancer Center at Robert Wood Johnson University Hospital Somerset has been honored with the prestigious Outstanding Achievement Award from the Commission on Cancer of the American College of Surgeons. The hospital is also distinguished for its Joint Surgery Institute, receiving the Joint Commissions Gold Seal of Approval for total knee and total hip replacement surgery, and is designated as a Primary Stroke Center by the Joint Commission and the New Jersey Department of Health and Senior Services. Robert Wood Johnson University Hospital Somerset has been named a Center of Excellence in Metabolic and Bariatric Surgery by the Surgical Review Corporation. In addition, it has received the Joint Commissions Gold Seal of Approval for its acute myocardial infarction program.

Honored as a Leader in LGBT Healthcare Equality by the Human Rights Campaign, the hospital was the first in New Jersey to offer primary care services for the LGBTQIA community.

Robert Wood Johnson University Hospital Somerset also offers outpatient services at convenient locations in Central New Jersey, including physical therapy services in Bedminster, Bridgewater, Hillsborough, Princeton and Flemington and an urgent care center and a sleep disorders center in Hillsborough. In addition, the hospitals affiliated physician practices provide care for families throughout its community.

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ROBERT WOOD JOHNSON UNIVERSITY HOSPITAL SOMERSET ADDS BEHAVIORAL HEALTH THERAPIST DEDICATED FOR MEMBERS OF LGBTQ+ COMMUNITY - InsiderNJ

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Indian J Med Res. 2021 Apr;154(4):559-570. doi: 10.4103/ijmr.IJMR_313_19.

ABSTRACT

Immune checkpoint inhibitors (ICIs) are a relatively newer class of drugs approved for the treatment of malignancies such as melanoma, renal, bladder and lung cancer. Immune-related adverse events (IrAEs) involving the endocrine system are a common side effect of these drugs. The spectrum of endocrine adverse events varies by the drug class. Cytotoxic T-lymphocyte-associated antigen-4 inhibitors commonly cause hypophysitis/hypopituitarism, whereas the incidence of thyroid disease is higher with programmed cell death (PD)-1/ ligand (PD-L) protein 1 inhibitors. The focus of this review is to describe the individual endocrinopathies with their possible mechanisms, signs and symptoms, clinical assessment and disease management. Multiple mechanisms of IrAEs have been described in literature including type II/IV hypersensitivity reactions and development of autoantibodies. Patients with pre-existing autoimmune endocrine diseases can have disease exacerbation following ICI therapy rather than de novo IrAEs. Most of the endocrinopathies are relatively mild, and timely hormone replacement therapy allows continuation of ICIs. However, involvement of the pituitary-adrenal axis could be life-threatening if not recognized. Corticosteroids are helpful when the pituitary-adrenal axis is involved. In cases of severe endocrine toxicity (grade 3/4), ICIs should be temporarily discontinued and can be restarted after adequate hormonal therapy. Endocrinologists and general internists need to be vigilant and maintain a high degree of awareness for these adverse events.

PMID:35435341 | DOI:10.4103/ijmr.IJMR_313_19

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The side effects of immune checkpoint inhibitor therapy on the endocrine system - DocWire News