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Category Archives: Biotechnology

The Minneapolis Medical Research Foundation Selects Goodwin Biotechnology to Help Develop and Manufacture … – PR Newswire (press release)

Posted: March 20, 2017 at 5:44 pm

"For over 15 years, Goodwin Biotechnology has been one of the pioneers in providing development services and GMP manufacturing of a broad portfolio of Antibody:Drug Conjugate (ADC) and Protein:Drug Conjugate (PDC) projects, including cytotoxic ADCs, Radio-Immunoconjugates, Antibody:Peptide Conjugates, Antibody:Dye Conjugates, PEGylated proteins, and other bioconjugates including Biobetters," said Muctarr Sesay, Ph.D., Chief Scientific Officer at Goodwin Biotechnology. "Our experience in Bioconjugation has resulted in several patents and publications, as well as proprietary processes that enable us to help our clients overcome some significant challenges in developing their next generation of bioconjugates. When including our experience in manufacturing vaccines for use in early- and late-stage clinical trials, we found the Minneapolis Medical Research Foundation project to be highly intriguing."

"This is not an unusual approach for us when we initiate a project because we collaborate with many of our clients in the early stages of proof of concept/development by empirically recommending the appropriate processes to create a viable ADC or PDC candidate," Dr. Sesay continued. "We then blend that with a solutions-oriented approach to help our clients overcome significant challenges to ensure that the process for their candidate is robust, compliant, economical, and scalable."

"We are proud to help advance the treatment for this growing public health concern because we're confident in the expertise that our highly skilled scientists have developed in the areas of ADCs and PDCs, based on the successful work that we have done with over 400 client projects over the last 24 plus years," said Karl Pinto, Chief Executive Officer at Goodwin Biotechnology, Inc. "Our Bioconjugation capabilities complement our experience in successfully developing and manufacturing monoclonal antibodies, recombinant proteins, and vaccines through mammalian cell culture expression systems. So, as part of our Single Source Solution, Goodwin is uniquely qualified to partner with our clients to meet their needs by developing customized and flexible approaches for manufacturing antibodies and recombinant proteins, for example, and / or design the appropriate conjugation activities to cost effectively deliver their product candidates on time."

About the Minneapolis Medical Research Foundation

The Minneapolis Medical Research Foundation (MMRF) is a subsidiary of Hennepin Healthcare System, Inc., and operates as the research arm of Hennepin County Medical Center, an acute care research and teaching hospital in Minneapolis. MMRF is one of the largest nonprofit medical research organizations in Minnesota and consistently ranks in the top 10 percent of all institutions receiving research funding from the National Institutes of Health. To learn more, visit mmrf.org.

About Goodwin Biotechnology, Inc.

Goodwin Biotechnology is a uniquely qualified CDMO that offers a Single Source Solution for our clients from cell line development (through our strategic partner), exploratory proof of concept projects through process development and cGMP contract manufacturing of monoclonal antibodies, recombinant proteins, vaccines, and Biologic Drug Conjugates including Antibody:Drug Conjugates (ADCs) for early and late stage clinical trials. By working with Goodwin Biotechnology, clients can enhance the value of their product candidates with clear development and manufacturing strategies, as well as a road map to meet the appropriate quality requirements from the milligram and gram range to kilogram quantities as the product candidates move along the clinical development pathway in a cost-effective, timely, and cGMP compliant manner to enhance patients' lives. With over 20 years of experience as an independent integrated contract manufacturer, Goodwin Biotechnology has worked as a strategic partner with numerous companies of all sizes from small university spin-offs to major research institutes, government agencies and large, established and multi-national biopharmaceutical companies. Based on the impressive track record, Goodwin Biotechnology has been awarded Frost & Sullivan's Customer Value and Leadership Award for Best Practices in Mammalian Contract Manufacturing in 2014.In addition, Goodwin Biotechnology was awarded 'Best in Sector: Biopharmaceutical Contract Development & Manufacturing' at Acquisition International magazine's 2015 Sector Performance Awards. Most recently, Goodwin Biotechnology received Global Health & Pharma's award for Best for BioProcess Development & cGMP Manufacturing in 2016, and Best in Mammalian Cell Culture Process Development & cGMP Manufacturing 2017. Click here to view the press releases!Additional information may be found at http://www.GoodwinBio.com.

Funding for this study was supported by the National Institute on Drug Abuse of the National Institutes of Health under Award Number U01DA038876. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

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http://www.goodwinbio.com

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The Minneapolis Medical Research Foundation Selects Goodwin Biotechnology to Help Develop and Manufacture ... - PR Newswire (press release)

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SalvaRx Group invests $1m in US biotechnology firm – DIGITALLOOK

Posted: March 20, 2017 at 5:44 pm

SalvaRx Group is to invest $1m in Rift Biotherapeutics, a US biotechnology company that develops antibodies for use in oncology.

Following the investment, the company will hold about 30% stake in Rift, including new shares issued on the $90,000 loan already provided to Rift.

SalvaRx will have the option to invest up to $1.5m further if Rift achieves certain development targets, and will also have the option to buy all outstanding shares in Rift in exchange for new shares in SalvaRx.

Rift develops antibodies implicated in the inflammatory tumour and tumours infiltrating the immune cells microenvironment, and it recently won the Boehringer Ingelheim Innovation prize, which included additional laboratory space at BioLabs San Diego, an incubator for biotech start-ups.

SalvaRx chief executive Ian Walters said that the companys collaboration with Rift will provide it with financing to finish preclinical development and will also augment its team with SalvaRx's clinical development expertise.

Dr Miguel de los Rios, Rift's founder and chief executive, added: "Our novel non T-cell based immunotherapy targets offer complementary approaches to the current standard of care in immuno-oncology. We are researching the anti-tumour activity of our immunotherapy and potential utility with standard of care agents such as Opdivo, Keytruda, or Tecentriq.

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Exploring the cloud laboratory: biotechnology and cloud computing – Information Age

Posted: March 20, 2017 at 5:44 pm

Cloud computing within the biotech sector can take big data analysis to the next level by means of performance, connectivity, on-demand infrastructure and flexible provisioning

The continued drive for innovation puts immense pressure on IT departments to develop new technologies at speed, while also making sure that they do this cost effectively.

Add to this the fact that, more so than other industries, biotech firms are extremely tightly regulated. As a result, IT groups within this industry are often reluctant to introduce more complexity into what is already a very complex environment.

To them, expanding a data centre can often feel a whole lot easier than navigating the regulations of the cloud. Despite this, growth in the demand for cloud computing in life sciences research and development is escalating due to the benefits it brings to the industry benefits like exceeding regulatory requirements, for example.

iland haveworked with many companies in the healthcare, life sciences and biotech industries. Therefore, it knowsfrom experience that the implementation of cloud computing in biotechnology empowers organisations with the control and flexibility needed to lead the way in both the research world as well as the businesses world.

>See also:10 trends that will influence cloud computing in 2017

For example, ilandrecently worked with a US based biotechnology organisation on their backup and disaster recovery (DR) strategy, and were able to drive global data centre consolidation with host-based replication to the cloud. As a result, itsDR testing and auditing processes were greatly simplified and streamlined which drove significant cost savings as well as compliance assurance.

If you still need convincing here are three additional key benefits that cloud brings to biotech organisations.

When the Human Genome Project began it was one of the most extensive research projects in the field to date costing billions of pounds and lasting over a decade.

These days, thanks largely to cloud technology, it can be done in just 26 hours. Things such as drug R&D, clinical research as well as a whole host of other areas have benefited just as much from the rapid growth of computational power. The better your technology is at crunching huge sets of data, the quicker you can innovate.

Cloud computing within the biotech sector can take big data analysis to the next level by means of performance, connectivity, on-demand infrastructure and flexible provisioning.

Labs can also benefit from immense computing power without the cost and complexity of running big onsite server rooms. They can also scale up at will in order to make use of new research and ideas almost instantly.

Concerns have been voiced that so called scientific computing in the cloud may make results less reproducible. One concern is that cloud computing will be a computing black box that obscures details needed to accurately interpret the results of computational analyses.

>See also:How cloud computing can transform the pharmaceutical industry

In actual fact, by leveraging the application program interfaces (APIs) in the iland cloud, biotech customers are able to integrate cloud data back into on-premises IT systems to ensure that data analyses done in the cloud can be easily shared and consumed by other applications.

Essentially, cloud computing services bring more players to the table to solve the giant puzzle. Its a win-win situation from an economic and patient standpoint, and several big name companies are jumping on the biotech cloud bandwagon.

Biotech companies need to maintain strong access and authentication controls, while also being able to collaborate easily. For this reason audit trails and other measures are often required to verify that information has not been improperly altered, and that good experimental and manufacturing procedures have been followed.

At the same time bio-technologists need to be able to access and share data across multiple departments or even multiple companies.

Cloud computing in biotechnology makes this all possible it centralises data, ensuring security and data sovereignty while facilitating collaboration.

It supports extensive user and role based access control, two-factor authentication and integrity monitoring to prevent improper access and changes. In addition to data encryption, vulnerability scanning and intrusion detection, these measures facilitate security and compliance, without disrupting the internal workflow.

Complex regulatory requirements and logistics combined with niche markets make efficiency paramount within biotechnology. Even minor mistakes as a result of sloppy process management can easily result in major issues.

Real-time operational reporting dramatically improves efficiency, quality control and decision making, allowing organisations to react instantly to challenges and opportunities, both internal and external.

>See also:Managed cloud: making the most out of public cloud computing

As well as enhanced billing visibility and resource management functions, the release of the vendors secure cloud services means that the itscloud now includes on-demand security and compliance reports.

This advanced cloud management functionality is designed to foster strategic, self-sufficient control of a cloud environment, optimising overall cloud usage and costs to drive business initiatives and growth.

Without a shadow of a doubt, cloud technology can help biotechnology companies build the future. From research and development to marketing, computing affects everything an organisation does.

Sourced by Monica Brink, director of marketing, iland

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Puma Biotechnology Inc (NYSE:PBYI) Impact Score At 0 – Stock Observer

Posted: March 19, 2017 at 4:42 pm

Puma Biotechnology Inc (NYSE:PBYI) daily sentiment score is -0.018 for articles printed on 2017-03-18. This is on a -1-1 scale after assessing the buzzing news and its impact on the system. The assessment is hooked on the dependable web sources.

Bullish target is at $89 while conservative price target is $72 on respective equity.

Puma Biotechnology Inc has an ABR of 1.67. The stock rating was 1.67 in preceding quarter. Financial numbers can be released on 2017-05-09. Consensus estimated EPS is $-1.88 for this quarter.

Securities prices are motivated by fundamentals in both the controlled and open street. Informed or not, shareholders weightage is on fiscals and other allied valuation basics. The metrics under contemplation are per-share earnings and associated ratios. Investors shift their emphasis on comprehensive financial report. Also, they predict miscellaneous components, which consists the reserves and other firm resources and also its valuation to due debt. Definitely, it is an unusual exercise to assess and measure all features while generating funds in equity market. A disciplined appraisal bodes well when the notion is to contribute a fair part in planned income.

Whatever ratings Zacks gives can to some degree exhibit variance from calls of First Call. Both the entities dont poll same set of street analysts, and as a result the projections vary. Puma Biotechnology Inc (NYSE:PBYI) posted EPS of $-2.04 for period closed on 2016-12-31. The reported number was $-0.02 off from the consensus. In percentage terms variance was -0.99%.

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Puma Biotechnology Inc (PBYI) Moves Higher on Volume Spike for March 17 – Equities.com

Posted: March 18, 2017 at 5:45 am

Market Summary Follow

Puma Biotechnology Inc is a A biopharmaceutical company

PBYI - Market Data & News

PBYI - Stock Valuation Report

Puma Biotechnology Inc (PBYI) traded on unusually high volume on Mar. 17, as the stock gained 0.91% to close at $44.15. On the day, Puma Biotechnology Inc saw 2.2 million shares trade hands on 7,459 trades. Considering that the stock averages only a daily volume of 1.19 million shares a day over the last month, this represents a pretty significant bump in volume over the norm.

Generally speaking, when a stock experiences a sudden spike in trading volume, it may be seen as a bullish signal for investors. An increase in volume means more market awareness for the company, potentially setting up a more meaningful move in stock price. The added volume also provides a level of support and stability for price advances.

The stock has traded between $73.27 and $19.74 over the last 52-weeks, its 50-day SMA is now $35.79, and its 200-day SMA $42.49. Puma Biotechnology Inc has a P/B ratio of 7.77.

Puma Biotechnology Inc is a biopharmaceutical company. It is engaged in the acquisition, development and commercialization of products to enhance cancer care.

Headquartered in Los Angeles, CA, Puma Biotechnology Inc has 160 employees and is currently under the leadership of CEO Alan H. Auerbach.

For a complete fundamental analysis analysis of Puma Biotechnology Inc, check out Equities.coms Stock Valuation Analysis report for PBYI.

Want to invest with the experts? Subscribe to Equities Premium newsletters today! Visit http://www.equitiespremium.com/ to learn more about Guild Investments Market Commentary and Adam Sarhans Find Leading Stocks today.

To get more information on Puma Biotechnology Inc and to follow the companys latest updates, you can visit the companys profile page here: PBYIs Profile. For more news on the financial markets and emerging growth companies, be sure to visit Equities.coms Newsdesk. Also, dont forget to sign-up for our daily email newsletter to ensure you dont miss out on any of our best stories.

All data provided by QuoteMedia and was accurate as of 4:30PM ET.

DISCLOSURE: The views and opinions expressed in this article are those of the authors, and do not represent the views of equities.com. Readers should not consider statements made by the author as formal recommendations and should consult their financial advisor before making any investment decisions. To read our full disclosure, please go to: http://www.equities.com/disclaimer

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NAS Issues Report on Preparing for Future Products of Biotechnology – JD Supra (press release)

Posted: March 17, 2017 at 4:42 pm

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Analysts Set Puma Biotechnology Inc (PBYI) Price Target at $70.50 – The Cerbat Gem

Posted: March 17, 2017 at 4:42 pm


The Cerbat Gem
Analysts Set Puma Biotechnology Inc (PBYI) Price Target at $70.50
The Cerbat Gem
Shares of Puma Biotechnology Inc (NYSE:PBYI) have earned an average recommendation of Hold from the eight ratings firms that are presently covering the ...
Traders Recap: Puma Biotechnology Inc (NASDAQ:PBYI ...NYSE Journal (press release)
Puma Biotechnology Inc (NASDAQ:PBYI) Reviewed By Analysts ...The De Soto Edge

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Analysts Set Puma Biotechnology Inc (PBYI) Price Target at $70.50 - The Cerbat Gem

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Ceramics artist inspired by nature, biotechnology – Jewish News of Greater Phoenix

Posted: March 16, 2017 at 4:42 am

Ceramist Susan Beiners work has been exhibited in China, France, the Netherlands and across the nation, but it took some persuading to get her to exhibit her creations at Temple Solels latest Art Showcase.

After some cajoling, Beiner relented and now her earlier work is on display at Temple Solel through May 31. A reception and talk featuring Beiner are scheduled for 10:30 a.m. Sunday, April 2, at Temple Solel, 6805 E. McDonald Drive, Paradise Valley.

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Janet Perez is a freelance writer based in Phoenix.

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Ceramics artist inspired by nature, biotechnology - Jewish News of Greater Phoenix

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Nasdaq Composite Index Approaches Record High as … – Economic Calendar

Posted: March 16, 2017 at 4:42 am

The Nasdaq Composite Index rose Wednesday, buoyed by broad advances at biotechnology and IT companies, after the Federal Reserve decided to raise interest rates for the second time in three meetings.

The technology-heavy index rose 0.7% to 5,900.05, its fifth advance in the last six sessions. The benchmark index settled just below all-time highs.

With the gain, the Nasdaq has returned nearly 10% for the year, outpacing the S&P 500 Index and Dow Jones Industrial Average.

A total of 2,009 companies listed on the Nasdaq reported gains, versus 888 that finished lower and 229 that went unchanged. A total of 166 companies reported new highs, versus 47 that set new lows.

Health stocks listed on the S&P 500 rose more than 1%, with pharmaceuticals, biotechnology and life sciences leading the rally. Information technology also advanced 0.6% as a sector.

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The Nasdaq Biotechnology Index rose 1.5% to 3,162.82.

The Federal Reserve raised its benchmark interest rate by a quarter point to 1% in a move that was widely anticipated by the markets. Policymakers continue to expect three rate increases this year, putting the central bank on course for two additional adjustments in 2017.

In terms of upcoming releases, the U.S. Labor Department will report on initial jobless claims on Thursday. Separately, the Commerce Department will report on housing starts and building permits. The Philadelphia Fed will also report on regional manufacturing conditions in the early morning.

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Sri Lanka to set up Rs100mn Biotechnology Park in Homagama – Lanka Business Online

Posted: March 16, 2017 at 4:42 am

Mar 16, 2017 (LBO) Sri Lankas cabinet has agreed to establish the Biotechnology Innovation Park in the Nanotechnology Park in Pitipana, Homagama as a public-private partnership project.

This years budget allocated 100 million rupees for the establishment of this facility which will provide facilities mainly for companies engaged in the pharmaceutical industry and genomics.

Apart from the land, the government will also allocate utilities such as electricity and water for the proposed facility.

Global market for biotechnology is estimated at over 453 billion US dollars in 2016 with an annual growth of over 10 percent.

In 2013, Sri Lankas first ever Nanotechnology and Science Park was commissioned in Homagama with the government investing over 2 billion rupees and six private companies cumulatively investing 310 million rupees.

Potential Sectors for Sri Lankan Biotechnology Industry Development

Enzyme: food, detergent, garment etc. Synthetic biology Pharmaceutical: Vaccines( including recombinant), anti-venom, antibiotics, herbal product drug delivery mechanisms etc. Medical diagnostics : Genomics, regenerative medicine etc. Tissue engineering : production of cell lines Bioinformatics Clinical trails Bioenergy Neutraceuticals and therapeutics Bio-products : bio-fertilizer, bio-pesticides etc Marine biotechnology : medicinal, food, chemical Environmental biotechnology : waste management Agriculture Biotechnology : crop improvement molecular breeding, biotech crops etc.

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Sri Lanka to set up Rs100mn Biotechnology Park in Homagama - Lanka Business Online

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