Monthly Archives: October 2022

As the population ages, experts are working to understand factors that influence healthy aging and encourage a better quality of life. Type 2 diabetes (T2D) is a chronic metabolic disorder that can impact long-term health outcomes.

A new study published in the Journal of the American Geriatrics Society found that older adults diagnosed with T2D who had high levels of psychological resilience were more likely to have better physical functioning, higher quality of life, and a lower likelihood of frailty and self-reported disability.

Psychological resilience, or just resilience, depends on peoples ability to respond and adapt to complex events like stress or trauma. It has to do with bouncing back after experiencing hardship.

Anamara Ritt-Olson, Ph.D., an associate professor of health, society, and behavior at the School of Public Health at the University of California, Irvine, not involved in the study, explained resilience to MNT in this way:

Resilience is the incredibly common ability to both withstand and bounce back from adversity. It is the armor that we wear to weather the difficulties of life. We are often put in the spin cycle of life, but resiliency allows us to come out relatively unharmed.

Both internal and external factors impact resilience. People are different, so their levels of resilience are also different. For example, adults with greater levels of social support are more likely to have more robust levels of resilience.

Resilience can impact many aspects of peoples lives, including how they cope with chronic conditions. T2D is a chronic metabolic disorder that affects the bodys ability to use glucose for energy.

It requires careful long-term management. If left unmanaged, it can lead to severe health complications like diabetic nephropathy and heart disease. Experts are still researching the best disease management methods and factors influencing long-term health outcomes.

Experts in this current study wanted to examine how psychological resilience impacted health in older adults with T2D.

The study included over 3,000 older adult participants with T2D. These participants were originally enrolled in a clinical trial that compared different diabetes management interventions. Current study authors followed up with these participants on average fourteen and a half years later. They measured a few different components among the participants:

Overall, researchers found that higher levels of psychological resilience were associated with better health outcomes, including lower numbers of hospitalizations, better physical functioning and quality of life, and fewer symptoms of depression.

Study author KayLoni Olson, Ph.D., noted the following study highlights to MNT:

In this study, we found that among older adults with Type 2 diabetes, individuals who reported a greater degree of psychological resilience (being able to bounce back after stress) also reported better overall aging-related health. This includes metrics like fewer hospitalizations in the previous year, lower likelihood of meeting criteria for frailty, and greater mental well-being.

However, researchers also found some variation between the association of resilience with some metrics. They note that this indicates that some associations may differ based on race [or] ethnicity.

This particular study had a few limitations indicating the need for more in-depth research.

First, the study cannot determine causality. It was also a cross-sectional study, which means that the authors could not determine the directional relationship of the variables.

Other limitations are related to particular study and analysis methods. For example, they did not look at all of the sociocultural factors that may impact resilience. They also didnt examine specific aspects of aging, like cognitive function. The majority of participants were white and female, which can limit the generalization of the studys findings.

Dr. Ritt-Olson offered the following insights and words of caution:

Their findings suggest that when older adults build their resiliency, they will find benefits it both their mental and physical strength. They may even be able to avoid hospitalizations. There are challenges with the study that the authors also acknowledge, for example, their measure of resiliency is about your general perception of how quickly you bounce back. We can overestimate our abilities to bounce back, and it isnt tied to an actual event that one needed to adapt to.

Regardless, the study offers insight into the important relationship between the mind and the body. Further research can confirm the impact of psychological resilience and provide longer-term follow-up.

The current study cant tell us if psychological resilience causes better overall health or vice versa, which means that additional research is important for teasing these relationships apart, Dr. Ritt-Olson noted.

In the short term, incorporating concepts like resilience into the study of aging may not only contribute to a more holistic understanding of the aging experience but may also help expand the narrative around aging so that individuals feel empowered as opposed to passive participants. This intersects with efforts within the aging research community to define healthy aging not just by the absence of health-related issues but also by the quality of later years of life.

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Resilience may improve health among older adults with type 2 diabetes - Medical News Today

WEDNESDAY, Oct. 12, 2022 (HealthDay News) -- The earlier a woman is diagnosed with diabetes, the sooner she may enter menopause, new research shows.

Rates of diabetes have grown steadily, so researchers wanted to understand the long-term implications of premenopausal diabetes on women's reproductive health.

Their study of more than 11,000 women found that being diagnosed with type 1 diabetes before age 30 or type 2 diabetes between 30 and 39 were both linked to earlier onset of menopause.

A diagnosis of type 2 diabetes after age 40, however, was associated with later menopause, compared to women without diabetes.

The researchers found no significant association between diabetes during pregnancy (gestational diabetes) and age at menopause.

"Even after adjusting for covariates associated with age at natural menopause, we still find an association between early diagnosis of diabetes and earlier menopause and a later diabetes diagnosis with a later age at menopause as compared to those who did not have diabetes," said lead study author Vrati Mehra, of the University of Toronto.

"We hope our work lays the foundation for more research in this area so we can better understand and prevent the long-term impacts of diabetes on the human body and the reproductive system," she added.

The findings are scheduled to be presented in Atlanta Thursday at a meeting of the North American Menopause Society (NAMS). Findings presented at medical meetings should be considered preliminary until published in a peer-reviewed journal.

NAMS medical director Dr. Stephanie Faubion said the research adds to growing evidence about the collective toll diabetes takes on the human body.

"In this case, it shows that young women living with a diagnosis of diabetes are more susceptible to accelerated ovarian aging and early menopause," Faubion said in a society news release.

More information

The U.S. Centers for Disease Control and Prevention has more on diabetes.

SOURCE: North American Menopause Society, news release, Oct. 12, 2022

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Years of Diabetes Could Speed Onset of Menopause | Health | derbyinformer.com - The Derby Informer

Among people with type 2 diabetes (T2D) attending diabetic retinopathy (DR) screening in Denmark, markers including insulin use were important predictors for the development of present, incident, and progressive DR.

A multivariable model indicated that patients who used insulin were 2.3 times more likely to have DR and they had a 1.92.4 times higher risk for DR-development or progression, while the use of cholesterol-lowering medicine was associated with a lower presence of DR.

However, through the follow-up period in 2013 2018, the nationwide cohort reported a considerably lower prevalence, incidence, and progression of DR, when compared with earlier reports.

Potential explanations for this might include that the recent years have led to better treatment and optimized risk factor control in diabetes, which might decrease the onset and progression of DR, said Jakob Grauslund, MD, PhD, Department of Ophthalmology, Odense University Hospital.

Duration of diabetes was reported as a leading indicator of DR and proliferative DR (PDR), being 2.45 and 9.79 times more frequent in patients with a duration of more than 20 years than those who were diagnosed within 10 years.

The team of investigators evaluated the prevalence and incidence of DR along with associated markers in patients with type 2 diabetes in the Danish DR-screening program between 2013 and 2018. Stages of DR were defined according to the International Clinical Diabetic Retinopathy Disease Severity Scale as levels 0 (no DR), 13 (mild, moderate, and severe non-PDR), or 4 (PDR).

Investigators linked data from the national Danish Registry of Diabetic Retinopathy (DiaBase) to various national health registries in order to retrieve information on diabetes duration, marital status, comorbidity, insulin use, and systemic medication.

The study included all 153,238 people with T2D (56.4% male) from the study period, with a mean age of 66.9 years and duration of diabetes at 5.3 years.

The rates of use of insulin, non-insulin glucose lowering drugs, blood pressure lowering therapy and cholesterol lowering therapy at the first screening episode were reported as 15.8%, 86.5%, 77.8%, and 77.3%, respectively. Most patients did not have DR at their first screening (91.2%).

The prevalence and 5-year incidences of DR, 2-step-or-more progression of DR and progression to PDR were 8.6%, 2.8%, 0.7%, and 0.2%, respectively.

Multivariable regression models indicate the prevalence of DR was associated with male sex (odds ratio [OR], 1.30; 95% CI, 1.25 1.36), age (OR, 0.77; 95% CI, 0.74 - 0.81 per 10 years of age), duration of diabetes (OR, 3.07; 95% CI, 2.96 3.18 per 10 years), and the use of insulin (OR, 2.34; 95% CI, 2.24 - 2.44).

The prospective part of the study determined the leading marker of incident DR and progression to PDR were duration of diabetes (hazard ratio [HR], 1.98; 95% CI, 1.87 - 2.09; HR, 2.89, 95% CI, 2.34 - 3.58 per 10 years of duration) and use of insulin (HR, 1.88; 95% CI, 1.76 - 2.01; HR, 2.40, 95% CI, 1.84 - 3.13).

Meanwhile, the use of cholesterol-lowering medication was considered a protective marker (HR, 0.87; 95% CI, 0.81 0.93; HR, 0.70; 95% CI, 0.52 - 0.93).

The study, Presence and development of diabetic retinopathy in 153,238 patients with type 2 diabetes in the Danish Registry of Diabetic Retinopathy, was published in Acta Ophthalmologica.

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Insulin Use May Predict the Development of Diabetic Retinopathy - MD Magazine

Type 1 diabetes is a condition that they both say is tough to deal with, not because of the physical ailments, but the social anxieties while at school.

CUYAHOGA COUNTY, Ohio Olivia and Marabelle are two Northeast Ohio teens that many would describe as typical teenagers.

If it wasn't for the beeping of their insulin pumps, you'd never know about the daily routine that has become just another part of their every day life.

Oliva and Marabelle were both born with type 1 diabetes.

A condition that they both say is tough to deal with, not because of the physical ailments, but the social effects they deal with while relying on those insulin pumps.

They don't try to do anything to bring attention to their condition while in school, but the loud beeping of the pumps bring attention to them whether they want it or not.

Oliva said, "When my pump would beep [in class], kids would freak out. When does it usually go off if my blood sugar is high or low. Or sometimes if I forget to turn my insulin back on after a shower.

They say it hasn't only been a struggle with feeling different compared to their classmates, but incidents with teachers thinking their devices are cell phones being used in class causes anxiety when the machines are working to provide them their necessary medicine.

Oliva continued, "One time I was giving myself insulin in class, my teacher was walking around and said 'Do I see a phone?' The whole class turned around. She looked under my desk and saw my pump and said, 'never mind'"

Technology has come a long way in helping children born with type 1 diabetes manage their insulin intake. Phones now connect to pumps via Bluetooth and help monitor blood sugar levels easier than ever before.

However one issue that still remains that technology hasn't come up with a solution for, the social ramifications of feeling "different" in a way not many others can understand.

Marabelle's mother Kari says schools are made aware of conditions like type 1 diabetes and should make sure every staff member knows about the accommodations allowed to these students by law.

"When [students] have something similar [to type 1 diabetes] they get a 504 plan through the school that gives them extra accommodations for test taking if they are over 300 they have the option to postpone. If they are not aloud to eat in class they can because they need it to stay healthy.

More than 200,000 kids have type 1 diabetes in the United States. It is an every day battle to stay healthy not only physically, but mentally and emotionally too.

Marabelle shares that she just wants to be looked as as a normal teen, "I'm not as different as you think I can still do normal stuff and that my pump beeping isn't a big deal."

The Juvenile Diabetes Research Foundation (JDRF) will be holding its "One Walk" event coming up on Sunday, October 16 at Cleveland Metroparks Zoo. Money raised for the event will go towards JDRF's battle to conquer type 1 diabetes. Click here to register or make a donation.

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2 Northeast Ohio teens born with type 1 diabetes deal with social anxieties of their condition at school - WKYC.com

What and how you eat directly impacts your risk of developing type 2 diabetes. So, it's simple logic to make a habit of reducing the stuff that most directly leads to the deadly disease: sugar.

An estimated 34 million Americans have diabetes, more than 10% of the U.S. population, according to the National Institutes of Health. Another 88 million adults or 34.5% of Americans have prediabetes, a disorder characterized by blood sugar levels that are high but not yet to the level indicating type 2 diabetes.

When your body doesn't produce enough insulin or uses it ineffectively to keep your blood sugar in a healthy range, that's called insulin resistance. Your cells become numb to the hormone and can't efficiently use glucose for energy. Insulin resistance often leads to type 2 diabetes.

The disease is so common (as the numbers above suggest) that many people may not be aware of how serious and frightening it is. Type 2 diabetes is associated with obesity, cardiovascular disease, nonalcoholic fatty liver, and dementia.

If understanding the devastating potential outcomes of a diabetes diagnosis has renewed your interest in being more aware of your sugar intake, great! But here's another idea: Instead of focusing on cutting carbs and sugars out of your diet, establish eating habits that prevent diabetes. Since sacrificing the foods you love can be so unpleasant, focus on how you can eat healthy without denying yourself. That gets to the most crucial eating habit for avoiding diabetes, according to many nutrition experts:

"The diet we should all be on is the optimal diet of people with diabetes," says registered dietitian nutritionist Wendy Bazilian, Dr.PH, RDN, a doctor of public health and exercise physiologist certified by the American College of Sports Medicine. "You want a stable, steady release of blood glucose to enter the cells to make energy efficiently."

This is because stable blood sugar is critical to optimal metabolic health. And it affects many facets of your overall healthyour energy, sleep, mood and cognition, and immune system function.

"Uneven eating patterns, like skipping meals and eating heavily at dinner because you're starving, cause too many blood sugar spikes, which increases risk for diabetes," says registered dietitian Catherine Sebastian, MS, RD, manager of health communications at The Wonderful Company.

That advice may sound radical, but it's very logical and doable, because it's essentially the same healthy eating style that supports heart health, reduces inflammation, prevents weight gain and obesity, and reduces risk of certain cancers.

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Another important thing to consider when "eating like you already have diabetes" is that you don't need to cut out carbs completely.

"Cutting out carbs is a misconception," says Sebastian. "You want carbohydrates that contain fiber. And you should always have a protein source in every meal."

And some fat, adds Dr. Bazilian. "Have protein, fat, and carbs in your meal." Having the three macronutrients ensures you're getting nutrients, including fiber, that slow the absorption of sugars into the bloodstream as well as promote satiety.

Making a habit of eating like someone who already has diabetes can be challenging, just as establishing any routine can be. The key is to make a decision to commit to your health and well-being before making any changes to your day-to-day life, says Nick Frye, MS, a licensed clinical professional counselor and behavioral counseling manager for OPTAVIA, a weight loss and health coaching company.

The first step is finding your "why," "which is what we call the fundamental choice," he says. "It's an intentional commitment to identifying and following your north star. It's a mindset shift that sets direction and foundation for future action. All other habits to come are made in service to your fundamental choice."

So, for example, if eating like a diabetic is the habit you want to adopt, the first step is to determine what you want to get out of that habit. If it's "to optimize my health and avoid diabetes," personalize it with something emotionally meaningful to you, like "so I can be healthy enough to dance at my granddaughter's wedding in 20 years."

"Mindfully and intentionally become the author of your story," suggests Frye. "Skipping this mental exercise and jumping prematurely into action may deliver temporary success but is likely to result in long-term failure."

Remember Newton's First Law of Motion? A body at rest will remain at rest unless acted upon by an outside force. Well, that's the principle behind habit creation: you must start moving and then keep moving. Frye recommends starting small with micro-habits because "small, repeatable behaviors lead to significant results. Habits set people up for sustainable change."6254a4d1642c605c54bf1cab17d50f1e

You can find advice on how to eat like a diabetic on the American Diabetes Association website and elsewhere. But to start, build these micro-habits into your day and see where they take you.

"Put something in your mouth, break your fast," advises Carly Knowles, MS, RDN, a registered dietitian nutritionist with Organic Valley, an independent cooperative of organic farmers. "It fixes so much. It sets a mindset shift that food is a priority."

Knowles also works in private practice with women with gestational diabetes. She says her golden piece of advice to them is to eat for energy in the morning. "It's not so important what you eat but that you eatcould be five almonds or a few spoonfuls of yogurtsomething. Otherwise, you may get to lunch with a blood sugar crash, causing brain fog, cravings, and binge eating."

If you're trying to avoid white bread by switching to 100% whole wheat but are having trouble making the switch, go half and half. "Make half of your daily grains whole grains and half refined grains that are enriched," suggests Elana Natkier, MS, RD, a registered dietitian and consultant to the Grain Foods Foundation.

Eating the enriched bread won't increase your risk of diabetes, and it will ensure you're getting the added iron, folate, vitamin A, and thiamine. Natkier points to a 2019 analysis of studies in Advances in Nutrition, which found no association between refined grain intake and risk of type 2 diabetes when comparing the highest and lowest intake groups.

Brazilian also recommends establishing this micro-habit: Stand up after you finish a meal. The act alone marks a transition and signals to your brain that the meal is completed. "Standing up starts the mechanics of digestion and it starts to tell our cells to open up to receive blood sugar," Bazilian adds. For the same reason, go for a walk after every meal. She cites a study in Sports Medicine, showing that even just two minutes of walking after a meal can improve blood sugar levels when compared to sitting or laying down.

Have a glass of water before every meal. It'll likely satisfy the intense hunger and help you avoid overeating. "Eating too much food can also make your blood sugar out of balance," says Bazilian. Too much of any one macronutrient can be detrimental to health, too.

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The Most Crucial Eating Habit To Prevent Diabetes - Eat This, Not That

Newswise CLEVELAND University Hospitals has received national recognition, with two awards from the American Heart Association and other entities, for its care of patients with uncontrolled blood pressure, diabetes, heart disease, and stroke. These are some of the most common and devastating conditions plaguing the health of Americans today. The UH Primary Care Institute (PCI) and UH Population Health drove this effort.

High blood pressure (BP), or hypertension, is a leading risk factor for heart attacks, strokes, and preventable deathin the U.S. Nearly half of all adults in the country, 121.5 million people, are living with hypertension. Unfortunately, according to a study published in the Journal Circulation, less than half of them have their BP under control. Furthermore, Black Americans are more likely to have hypertension and suffer harm from it.

More than 37 million Americans have diabetes, and cardiovascular disease (CVD) is the leading cause of death for people living with type 2 diabetes. CVD is the leading cause of death and a major cause of heart attacks, strokes and heart failure for people living with type 2 diabetes.

Addressing blood pressure management is key for better cardiovascular health and is critical today, when heart disease and stroke continue to be leading causes of death for adults in the U.S., said Todd Zeiger, MD, who led this effort and at the time was Quality Medical Director for the Primary Care Institute at University Hospitals. Sona Kirpekar, MD, now leads quality for PCI. Receiving this recognition is a testament to the community that when they trust University Hospitals with their health, they will receive quality care.

At UH, were committed to optimizing care for the entire population of patients we serve, keeping them well and out of the hospital, said Peter Pronovost, MD, PhD, Chief Quality and Clinical Transformation Officer at UH. On our journey to zero harm, we are working diligently to ensure all patients have their blood pressure controlled. Were grateful to our primary care and other providers whove played such a significant role in making this happen as well as their patients whove committed to pursuing a healthier lifestyle.

These improvements are the result of an interdisciplinary effort where UHs Accountable Care Organization Population Health team, nurses, medical assistants, pharmacists, and PCI physicians work collaboratively to ensure patients have their blood pressure and diabetes controlled.This endeavor is one of several new ways in which UH seeks to optimize the care of patients with chronic disease by engaging primary care practices with specialists and patients to design primary care-centered resources around their needs.

Target: BP Gold+ Award

The American Heart Association and American Medical Association have awarded University Hospitals with the Target: BP Gold+ Award for its commitment to improving blood pressure control rates. The Gold+ award recognizes practices that demonstrate a commitment to measurement accuracy and in which high blood pressure is controlled in 70 percent or more of the affected adult patients.

Target: BP is a national collaboration between the American Heart Association and American Medical Association aimed at reducing the number of adults in the U.S. who suffer from heart attacks and strokes each year by urging physician practices, health systems, and patients to prioritize BP control.

Target: Type 2 Diabetes Participant Award

UH has also received the American Heart Associations Target: Type 2 Diabetes Participant Award for its commitment to addressing the relationship between diabetes and the risk of heart disease and stroke. The Participant Award recognizes practices that have completed data submission, including clinical measure entry, and committed to improving quality of care for patients with type 2 diabetes and cardiovascular risk factors.

Target: Type 2 Diabetes addresses heart disease and stroke risk factors in patients with type 2 diabetes as part of the Know Diabetes by Heart initiative, by the American Heart Association and American Diabetes Association, helping ensure the care provided to patients is aligned with the latest evidence- and research-based guidelines.

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About University Hospitals / Cleveland, Ohio Founded in 1866, University Hospitals serves the needs of patients through an integrated network of more than 20 hospitals (including 5 joint ventures), more than 50 health centers and outpatient facilities, and over 200 physician offices in 16 counties throughout northern Ohio.The systems flagship quaternary care, academic medical center, University Hospitals Cleveland Medical Center, is affiliated with Case Western Reserve University School of Medicine, Oxford University and the Technion Israel Institute of Technology. The main campus also includes the UH Rainbow Babies & Children's Hospital, ranked among the top childrens hospitals in the nation; UH MacDonald Women's Hospital, Ohio's only hospital for women; and UH Seidman Cancer Center, part of the NCI-designated Case Comprehensive Cancer Center. UH is home to some of the most prestigious clinical and research programs in the nation, with more than 3,000 active clinical trials and research studies underway. UH Cleveland Medical Center is perennially among the highest performers in national ranking surveys, including Americas Best Hospitals from U.S. News & World Report. UH is also home to 19 Clinical Care Delivery and Research Institutes. UH isone of the largest employers in Northeast Ohio with more than 30,000 employees. Follow UH on LinkedIn, Facebook and Twitter. For more information, visitUHhospitals.org.

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University Hospitals nationally recognized for efforts to reduce uncontrolled blood pressure; address relationship between diabetes, heart disease,...

Tandem Diabetes Care TNDM has observed the following analyst ratings within the last quarter:

According to 5 analyst offering 12-month price targets in the last 3 months, Tandem Diabetes Care has an average price target of $75.2 with a high of $90.00 and a low of $49.00.

Below is a summary of how these 5 analysts rated Tandem Diabetes Care over the past 3 months. The greater the number of bullish ratings, the more positive analysts are on the stock and the greater the number of bearish ratings, the more negative analysts are on the stock

This current average represents a 38.99% decrease from the previous average price target of $123.25.

Ratings come from analysts, or specialists within banking and financial systems that report for specific stocks or defined sectors (typically once per quarter for each stock). Analysts usually derive their information from company conference calls and meetings, financial statements, and conversations with important insiders to reach their decisions.

Some analysts publish their predictions for metrics such as growth estimates, earnings, and revenue to provide additional guidance with their ratings. When using analyst ratings, it is important to keep in mind that stock and sector analysts are also human and are only offering their opinions to investors.

If you want to keep track of which analysts are outperforming others, you can view updated analyst ratings along withanalyst success scores in Benzinga Pro.

This article was generated by Benzinga's automated content engine and reviewed by an editor.

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5 Analysts Have This to Say About Tandem Diabetes Care - Tandem Diabetes Care (NASDAQ:TNDM) - Benzinga