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Monthly Archives: July 2022
Carl Zeiss Meditec and Precise Bio Announce Partnership in the Development and Commercialization of Tissue-Based Implants for Ophthalmology USA -…
Posted: July 19, 2022 at 2:11 am
The companies will jointly develop 4D bio-fabricated corneal transplants for diseases that require endothelial keratoplasty and natural lenticule transplants
Carl Zeiss Meditec will invest in Precise Bio and fund the further development of Precise Bio's two cornea transplant products and has exclusive worldwide commercialization rights for these products
JENA, Germany and WINSTON SALEM, N.C., July 18, 2022 /PRNewswire/ -- Carl Zeiss Meditec and Precise Bio, a regenerative medicine company advancing the use of bio-printed tissues and organs, announced today that the companies have entered into a partnership to develop and commercialize fabricated corneal tissue for transplants in patients that require endothelial keratoplasty and natural lenticule transplants for treating keratoconus and vision correction.
Under the terms of the agreement, Carl Zeiss Meditec will invest in Precise Bio and fund the further development of Precise Bio's two cornea transplant products and has exclusive worldwide commercialization rights for these products. Financial terms were not disclosed.
"This investment in Precise Bio is expected to complement our leading portfolio of cataract and corneal refractive workflow solutions," said Euan S. Thomson, PhD, President of Ophthalmic Devices and Head of the Digital Business Unit for Carl Zeiss Meditec. "The technology has the potential to advance treatment options for corneal disease, as well as for elective procedures furthering enabling optimization of patient care."
"We are very excited with this partnership that builds on our successful, ongoing collaboration with ZEISS for the development of corneal tissues to address unmet needs in the field of ophthalmology," stated Aryeh Batt, Co- Founder and CEO of Precise Bio. "This strategic agreement leverages ZEISS' global leadership in ophthalmology and Precise' innovative and unique 4D bio-fabrication platform technology. We are confident that the synergy between the two companies will allow us to develop breakthrough solutions for recovering patients' eyesight, bringing hope to hundreds of millions of patients worldwide."
Precise Bio combines engineering, biomaterials, cell technology, bioengineering, and 3D printing into an unparalleled 4D bio-fabrication platform for transplantable organs and tissues. The Company's proprietary platform technology allows to fabricate tissues by 'printing' cells in a single-cell resolution and spatial accuracy, enabling complex organoid constructs with both structural integrity and long-term cell viability. Overcoming multiple technology challenges, Precise Bio's 4D bio-fabrication technology allows to reliably scale up tissue engineering for clinical use, and produce large quantities in a reproducible, quality controlled and cost-effective process. Precise Bio's ophthalmological pipeline consists of three products, the two cornea products that are the subject of the collaboration with Carl Zeiss Meditec and a retinal implant for age-related macular degeneration, all of which demonstrated successful results in animal models. The Company's ophthalmological products address global markets exceeding $10 billion annually.
Bio-fabricated tissues comprised of human cells and natural materials, mimicking the anatomical structure and natural tissue components, can replace damaged or diseased tissue, substitute for donor tissue in cases where there is lack of tissue or solve unmet therapeutic needs.
About ZEISSCarl Zeiss Meditec AG (ISIN: DE 0005313704), which is listed on the MDAX and TecDAX of the German stock exchange, is one of the world's leading medical technology companies. The Company supplies innovative technologies and application-oriented solutions designed to help doctors improve the quality of life of their patients. The Company offers complete solutions, including implants and consumables, to diagnose and treat eye diseases. The Company creates innovative visualization solutions in the field of microsurgery. With approximately 3,531 employees worldwide, the Group generated revenue of 1,646.8m in fiscal year 2020/21 (to 30 September).
The Group's head office is located in Jena, Germany, and it has subsidiaries in Germany and abroad; more than 50 percent of its employees are based in the USA, Japan, Spain and France. The Center for Application and Research (CARIn) in Bangalore, India and the Carl Zeiss Innovations Center for Research and Development in Shanghai, China, strengthen the Company's presence in these rapidly developing economies. Around 41 percent of Carl Zeiss Meditec AG's shares are in free float. The remaining approx. 59 percent are held by Carl Zeiss AG, one of the world's leading groups in the optical and optoelectronic industries.
For further information visit:www.zeiss.com/med
About Precise BioPrecise Bio develops regenerative medicine therapies that can transform patient care across a wide range of medical indications. Precise Bio's proprietary, break-through 4D bio-fabricating platform overcomes limitations of existing extrusion and ink-jet printers and paves the way for fabricating clinically viable tissues and organs. The Company's initial product pipeline is focused on ophthalmology and includes fabricated functional corneal grafts, intrastromal lenticules for treating keratoconus and vision correction,and a retinal implant for age-related macular degeneration. The Company also has earlier R&D programs to address unmet needs in additional medical indications, which are limited by the number of available donor tissues and organs, or where today's critical health problems can be solved using Precise Bio's naturally-based, hyper-accurate technology.
Precise Bio was founded in 2016 by Prof. Anthony Atala, MD, Director of the Wake Forest Institute of Regenerative Medicine (WFIRM), Prof. Shay Soker, PhD, from WFIRM and Mr. Aryeh Batt, who developed the Company's transformative laser printing technology. The Company operates out of two centers, in Winston Salem, NC and Modi'in, Israel.For more information, please visit http://www.precise-bio.com.
Photo - https://mma.prnewswire.com/media/1860898/Precise_Bio_Cornea.jpg
Precise Bio contact for investors:Eyal ArieliCFO/COOPrecise BioPhone: +972 76 539 1001[emailprotected]
Precise Biocontact for press / media:Tsipi HaitovskyGlobal Media LiaisonPrecise BioPhone: +972 52 598 9892[emailprotected]
ZEISS contact for investors:Sebastian FrericksDirector Investor RelationsCarl Zeiss Meditec AGPhone: +49 3641 220-116[emailprotected]
ZEISS contact for the press / media:Laurie FergusonHead of Global Communications Ophthalmic DevicesCarl Zeiss MeditecPhone: +1 925 719 7825[emailprotected]
SOURCE Precise Bio
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Tokyo Medical and Dental University Team Succeeds with First Mini Organ Transplant – JAPAN Forward
Posted: July 19, 2022 at 2:11 am
A Tokyo Medical and Dental University (TMDU) team announced on July 7 that it has conducted the worlds first clinical transplant of a mini organ into a patient with ulcerative colitis, an intractable disease. Part of a clinical study, the mini organ is made from cells obtained from the patient, and functions like a large intestine.
Researchers hope that the therapeutic method can possibly repair the ulcerated area of the intestine, which is difficult to treat with drugs. Its practical use as a new therapy in regenerative medicine is anticipated.
The surgery was conducted on an ulcerative colitis patient with refractory ulcers at the Tokyo Medical Dental University Hospital on July 5. Stem cells, which are tissue-building cells, were collected from the vicinity of a healthy colonic mucosa and cultured. Many spherical mini organs measuring at 0.1 ~ 1.2 millimeters were produced. These were then transplanted into the ulcerated area with an endoscope.
The surgery was successful and the patient was discharged from the hospital the following day. The team will monitor the patients condition over the next year to confirm safety and efficacy of the treatment.
At the press conference, Professor Ryuichi Okamoto stated, We were able to reach the starting line of a new medical therapy. We hope to continue a steady progression in our research and deliver the results to patients.
Mini organs are a collection of cells that bear the function and three-dimensional structure of actual organs. Also called organoids, their utilization in applied research in regenerative medicine is gaining momentum with various organs.
The surgery on July 5 is said to be the first ever full-scale organoid transplant to be conducted.
Ulcerative colitis is an intractable disease brought on for unknown reasons. It causes inflammation and ulcers along the mucosa of the colon, triggering symptoms such as abdominal pain and bloody diarrhea.
The number of patients is rapidly increasing, with an estimated 220,000 people affected in Japan. Symptoms can improve with anti-inflammatory drugs. However, if the disease becomes severe it could be difficult to repair or regenerate the ulcerated area using only symptomatic treatments available up to now.
Organoids bear a resemblance to the conditions of actual human tissues. Therefore, they are able to regenerate the ulcerated area because of their ability to attach to the affected area. Combined with the use of medication, a complete recovery is said to be possible.
(Read the report in Japanese at this link.)
Author: The Sankei Shimbun
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Tokyo Medical and Dental University Team Succeeds with First Mini Organ Transplant - JAPAN Forward
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Local Pain Medicine Practice Changes the Way Pain is Treated – PR Newswire
Posted: July 19, 2022 at 2:11 am
Treating Pain Origins with Minimally Invasive Techniques
CHALFONT, Pa., July 18, 2022 /PRNewswire/ -- Local Pain Medicine & Rehabilitation Practice, Pennsylvania Pain and Spine Institute (PA Pain and Spine) changes the way pain is treated with access to premier technologies and treatments unavailable elsewhere for patients in the region.
PA Pain and Spine is a professional medical center providing diagnostic and treatment services for various pain-related conditions in the Philadelphia region of Pennsylvania and beyond. With a team of highly qualified and trained providers, the Harvard-trained founders H. David Qu, MD and Robert Kelly, DO have led the practice to serve 800+ patients a week in both diagnosing and treating their chronic, pain-related conditions.
"Typically, when people hear the term 'Pain Management' they think of medication and a spiraling path of depression. When we started out and saw the available pain 'treatments' in the area, we realized there was a need for less medication and surgery and instead more true treatments. We wanted to be different. We wanted to learn everything we could to provide people in our community with the absolute best options available to treat any type of pain and related conditions at the source and allow them to get back to doing the things they love in life." states Founding Physician H. David Qu, MD.
The practice continues to grow to see more patients in need, beyond the Montgomery and Bucks counties in Pennsylvania, and offers access to various minimally invasive injection therapies, regenerative medicine therapies, medical acupuncture, cutting edge minimally invasive out-patient procedures and more all over the region.
With a strong focus on community support and helping people get their lives back, it comes as no surprise that the practice has hundreds of patient testimonials expressing how their lives have changed after working with this team.
"There is no limit for the future. We are constantly evolving and learning new treatment methodologies to better serve our community as the world changes. We want to be the team where people feel heard, and leave better than when they came in. The amount of dedication and passion our team has for helping others is limitless and we want to continue spreading this care across the state and beyond," states President and Founding Physician Robert Kelly, DO.
Patients and local community can learn more about the practice and the team of providers by visiting https://www.pennpain.com, or by calling the office at (215) 395-8888.
About PA Pain & Spine
Pennsylvania Pain and Spine Institute was founded in 2013 by Ivy League trained physicians Dr. David Qu, MD and Dr. Robert Kelly, DO. The practice is a pain management and rehabilitation privately-owned clinic with a focus on utilizing minimally invasive techniques and pain generator diagnostics in order to heal patients at the source. The practice currently has two offices located in Chalfont, Pennsylvania and Quakertown, Pennsylvania and treats patients with any type of pain.
Media Contact:Kelsey Voelker215.395.8888 x104[emailprotected]
SOURCE Pennsylvania Pain and Spine Institute
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Cell Separation Technologies Market Expands with Rise in Prevalence of Chronic Diseases, States TMR Study – GlobeNewswire
Posted: July 19, 2022 at 2:11 am
Wilmington, Delaware, United States, July 18, 2022 (GLOBE NEWSWIRE) -- Transparency Market Research Inc.: The market value of the global cell separation technologies market is estimated to be over US$ 20.3 Bn by 2031, according to a research report by Transparency Market Research (TMR). Hence, the market is expected expand at a CAGR of 11.9% during the forecast period, from 2022 to 2031.
According to the TMR insights on the cell separation technologies market, the prevalence of chronic disorders including obesity, diabetes, cardiac diseases, cancer, and arthritis is being increasing around the world. Some of the key reasons for this situation include the sedentary lifestyle of people, increase in the older population, and rise in cigarette smoking and alcohol consumption across many developed and developing nations. These factors are expected to help in the expansion of the cell separation technologies market during the forecast period.
Players in the global cell separation technologies market are increasing focus on the launch of next-gen products. Hence, they are seen increasing investments in R&Ds. Moreover, companies are focusing on different strategies including acquisitions and strengthening their distribution networks in order to stay ahead of the competition.
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As per the Imperial College London, chronic diseases are expected to account for approximately 41 million deaths per year, which seven out of 10 demises worldwide. Of these deaths, approximately 17 million are considered to be premature. Hence, surge in cases of chronic diseases globally is resulting into increased need for cellular therapies in order to treat such disease conditions, which, in turn, is boosting the investments toward R&Ds, creating sales opportunities in the cell separation technologies market.
Cell Separation Technologies Market: Key Findings
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Cell Separation Technologies Market: Growth Boosters
Cell Separation Technologies Market: Regional Analysis
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Cell Separation Technologies Market: Key Players
Some of the key players profiled in the report are:
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Cell Separation Technologies Market Segmentation
Modernization of healthcare in terms of both infrastructure and services have pushed the healthcare industry to new heights, Stay Updated with Latest Healthcare Research Reports by Transparency Market Research:
Cell Culture Market: Rise in outsourcing activities and expansion of biopharmaceutical manufacturers are expected to drive the cell culture market during the forecast period
Cell Culture Media, Sera, and Reagents Market: The global cell culture media, sera, and reagents market is majorly driven by growth and expansion of biotechnology & pharmaceutical companies and academic & research institutes.
Stem Cells Market: The global stem cells market is majorly driven by rising applications of stem cells in regenerative medicines. Increase in the number of chronic diseases such as cardiac diseases, diabetes, cancer, etc.
Cell Line Authentication and Characterization Tests Market: Increase in the geriatric population and surge in incidence of chronic diseases are projected to drive the global cell line authentication and characterization tests market.
CAR T-cell Therapy Market: The CAR T-cell therapy market is expected to clock a CAGR of 30.6% during the assessment period. The CAR T-cell therapy is known as a revolutionary treatment option for cancer, owing to its remarkably effective and durable clinical responses.
Cell & Tissue Preservation Market: Rise in investments in the field of regenerative medicine research is estimated to propel the market. Human blood, tissues, cells, and organs own the capability to heal damaged tissues and organs with long-term advantages.
Placental Stem Cell Therapy Market: Placental stem cell therapy market is driven by prominence in treatment of age-related disorders/diseases and increase in awareness about stem cell therapies are projected to drive the global market in the near future.
Biotherapeutics Cell Line Development Market: The market growth will be largely driven by research and development activities due to which, new solutions and technologies have gradually entered the market.
About Transparency Market Research
Transparency Market Research, a global market research company registered at Wilmington, Delaware, United States, provides custom research and consulting services. Our exclusive blend of quantitative forecasting and trends analysis provides forward-looking insights for thousands of decision makers. Our experienced team of Analysts, Researchers, and Consultants use proprietary data sources and various tools & techniques to gather and analyze information.
Our data repository is continuously updated and revised by a team of research experts, so that it always reflects the latest trends and information. With a broad research and analysis capability, Transparency Market Research employs rigorous primary and secondary research techniques in developing distinctive data sets and research material for business reports.
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Cell Separation Technologies Market Expands with Rise in Prevalence of Chronic Diseases, States TMR Study - GlobeNewswire
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Automating the Genomic Medicines of the Future – Bio-IT World
Posted: July 19, 2022 at 2:11 am
Contributed Commentary by Per Hammer, Cytiva
July 15, 2022 | Historically, the heavily regulated biopharma industry has been slow to adopt new technologies. However, a shift toward automation is vital to ensure that next-generation solutionssuch as cell and gene therapiesare produced at scale.
Less than one in five senior pharma executives strongly believe that frontier technologies, such as artificial intelligence, are widely adopted to support automation and increase the speed of specific processes. With cell therapies approved by global regulatory bodies, it is time to accelerate smart technologies and cell and gene therapy manufacturing.
Todays cell therapy treatments are often made on a small-scale, include manual preparation steps, and are produced for a clinical trial setting. Researchers spend days processing cellular material, monitoring its growth during the expansion phase, and preparing for re-administration to the patient. This process is demonstrated in administering autologous treatments so that every patient receives a unique living drug.
Though the current process is complex, it offers inspiring outcomes. For example, on April 1, 2022, the Food and Drug Administration (FDA) approved Kite Pharmas Yescarta, a chimeric antigen receptor (CAR) T-cell therapy for adult patients with large B-cell lymphoma. This kind of cancer is usually resistant to initial treatment and relapses within one year. With FDA approval, Yescarta (axicabtagene ciloleucel) is now the second-line treatment, a first for an autologous CAR T-cell therapy.
Cell Therapy Enters Mainstream
The exceptional results emerging from cell therapy clinical trials suggest we are entering a new phase of medical treatmentone where we can expect far more from our healthcare interventions than we ever imagined. Following the regulatory approval of autologous CAR T-cell therapies, the global cancer treatment landscape is changing, and the future is bright.
The success of COVID-19 vaccines signaled the arrival of the genomic medicines ageone where we hope to see cell and gene therapies deliver long-term remission and even cures for patients with some of the most complex diseases. According to the Alliance for Regenerative Medicine 2021 Annual Report, nearly 60% of the ongoing regenerative medicine clinical trials studied prevalent diseases by the end of the calendar year. But to get these powerful treatments to those who need them, we must have an automated manufacturing infrastructure that can generate cell therapies to meet increased demand in the coming years.
Saving Time Through Automation
Time is of the utmost importance, as biopharma manufacturing involves patient cells that have limited viability. Manual approaches to cell therapy production are time-consuming, and tasks such as checking cells at regular intervals during expansion are laborious. Another time-draining factor is the workflow and cleaning routines involved in maintaining a safe lab environment.
Automated solutions reduce or remove many of these challenges. After setting up a process, an operator can focus on other things while critical parameters such as temperature, pH level, gas transfer, and flow rates are monitored and controlled without human intervention.
Reducing Risks for Better Results
Manual cell processing solutions are complex, with many checkpoints across isolation, expansion, harvesting, and preservation stages. Unfortunately, each of these steps increases the risk potential. Despite the research teams expertise, there is still a chance that materials could be inadvertently contaminated during numerous open stages.
Additionally, limited process control can lead to difficulties in achieving high reproducibility. An automated modular solution minimizes these risks by bringing multiple steps within a closed, highly regulated, and controlled system.
Improving Manufacturing Efficiency
Changing a manufacturing process requires multiple manual routines and adjustments that must be checked and documented. However, documentation and protocols are less helpful when a customized process is used because they only apply to that specific setup.
Standardization would effectively improve manufacturing efficiency. This approach would ensure that what is learned in one project can be referenced in future work, with data and documentation applicable across different technology applications. A modular chain of connected systems allows for process variation with instruments running in customized configurations. Additionally, having control of an individual instrument leads to the straightforward use of built-in software and sensors.
Automated Manufacturing: The Way Forward for Cell and Gene Therapy
By using automated manufacturing to minimize human interaction, time, and resource requirements, it is possible to increase production speed and lower some risks and costs associated with commercialization.
The industry is ever-changing and adjusting its complex, yet exciting challenges will take some time. However, automation can create a significant advantage over competitors, providing the tools needed to produce cell therapies with the highest levels of safety and efficacy for patients.
Per Hammer has two decades of experience in the biopharma industry, mainly supporting customers in academics through process development and manufacturing. Per joined Cytiva in 2001, taking on several distinct roles in the company. Most recently, he progressed from Product Manager Leader for the Bioprocess Automation and Digital Team to Senior Global Product Manager for the Cell & Gene Therapy Automation and Digital Solutions. He can be reached at per.hammer@cytiva.com.
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Medical Nonwoven Disposables Market: Increase in Demand for Advancements in Wound Dressing Techniques to Drive the Market – BioSpace
Posted: July 19, 2022 at 2:11 am
Wilmington, Delaware, United States, Transparency Market Research Inc.: Medical nonwoven disposables are highly essential products in the healthcare field. Increase in popularity of these products has been observed as they provide better hygiene condition and reduce the contamination. Nonwoven products have many advantages over woven products.
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Nonwoven products include surgical gowns, face masks, drapes, surgeon caps, bandages, and others. Medical nonwoven disposables are made up from materials such as polypropylene, polyethylene, polyamides & polyesters, and others.
Medical nonwoven disposables products consist of high-quality fabrics for complete safety and immunity of healthcare professionals
The global medical nonwoven disposables market is driven by technological advancements in healthcare, increase in demand for advancements in wound dressing techniques, and rise in government initiatives for manufacturing nonwoven medical fabric. Moreover, demand for polyethylene is high due to low cost.
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Increase in prevalence of hospital-acquired infections among the geriatric population is expected to propel the medical nonwoven disposables market. According to the U.S. Department of Health & Human Product estimates, the U.S. is expected to have about 72.1 million geriatric population by 2030, which is more than twice the number in 2000.
As per a research paper published in the Current Opinion in Microbiology in 2018, lower respiratory tract infections which also include pneumonia, are the sixth leading cause of deaths due to hospitalizations in the U.S. and more than 90% of deaths occur in individuals who are 65 years old or more
Nonwoven medical disposables provide increased levels of protection against infectious diseases. In the past few years, nonwoven materials have shown significant reduction in post-operative infection rate compared to woven materials.
The risk of developing infection is nearly 2.5 times higher with woven products than nonwovens. Such factors help drive the medical nonwoven disposables market.
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Market Segmentation: Medical Nonwoven Disposables Market
Based on product, the global medical nonwoven disposables market has been divided into surgical products (drapes, gowns, caps, masks, and others), wound dressings (bandages, tapes, post-operative wound dressings, operative wound dressings, and dressing pads), and incontinence products (under pads and diapers)
In terms of material, the global medical nonwoven disposables market has been classified into polypropylene, polyethylene, acetate, rayon, polyamides & polyesters, acrylic, and others
In terms of end user, the global medical nonwoven disposables market has been categorized into hospitals, nursing homes, consumer & home healthcare, clinics, and ambulatory surgical centers
Each of the segments has been analyzed in detail for market trends, recent trends and developments, drivers, restraints, opportunities, and useful insights. The report provides current and future revenue (US$ Mn) for each of these segments from 2018 to 2028, considering 2019 as the base year. The compound annual growth rate (% CAGR) has been provided for each segment and market from 2020 to 2028 along with market size estimations.
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Regional Overview: Medical Nonwoven Disposables Market
In terms of region, the global medical nonwoven disposables market has been segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. The regions have been divided into major countries and sub-regions.
The current and future market value in terms of revenue (US$ Mn) of these regional markets and their major countries have been provided in the report from 2018 to 2028, with their CAGRs from 2020 to 2028.
The study also offers a list of recommendations, highlights, and useful insights of the market which would help new companies willing to enter the market and existing companies to increase market shares and help in the decision-making process.
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Major Players
The report concludes with the company profiles section that includes key information about the major players in the market
Leading players analyzed in the medical nonwoven disposables market include
Each of these players has been profiled in the report based on parameters such as company overview, financial overview, business strategies, product portfolio, business segments, and recent developments.
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Transparency Market Research, a global market research company registered at Wilmington, Delaware, United States, provides custom research and consulting services. Our exclusive blend of quantitative forecasting and trends analysis provides forward-looking insights for thousands of decision makers. Our experienced team of Analysts, Researchers, and Consultants use proprietary data sources and various tools & techniques to gather and analyze information.
Our data repository is continuously updated and revised by a team of research experts, so that it always reflects the latest trends and information. With a broad research and analysis capability, Transparency Market Research employs rigorous primary and secondary research techniques in developing distinctive data sets and research material for business reports.
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Insights on the Veterinary Medicine Global Market to 2027 – by Product, Animal Type, Route of Administration, Distribution Channel and Region – Yahoo…
Posted: July 19, 2022 at 2:11 am
DUBLIN, July 15, 2022 /PRNewswire/ --The "Veterinary Medicine Market: Global Industry Trends, Share, Size, Growth, Opportunity and Forecast 2022-2027" report has been added to ResearchAndMarkets.com's offering.
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The global veterinary medicine market reached a value of US$ 31.06 Billion in 2021. Looking forward, the publisher expects the market to reach a value of US$ 48.58 Billion by 2027, exhibiting a CAGR of 7.74% during 2021-2027. Keeping in mind the uncertainties of COVID-19, we are continuously tracking and evaluating the direct as well as the indirect influence of the pandemic on different end use sectors. These insights are included in the report as a major market contributor.
Veterinary medicine is a branch of science that deals in the prevention, control, diagnosis, and treatment of diseases that affect the health of domestic and wild animals. It helps maintain the health of food-producing animals, inhibit the transmission of zoonotic diseases from animal species to humans, and ensure a safe supply of food worldwide. At present, the escalating consumption of animal-derived products is increasing the adoption of veterinary medicines to monitor the health of agricultural animals and prevent human exposure to diseases.
The growing trend of nuclear families and inflating income levels have increased the overall spending of individuals on pets globally. This, in confluence with the rising concerns among pet parents about the well-being of their pets, represents one of the major factors supporting the demand for veterinary medicines.
The increasing penetration of pet insurance is further influencing the market growth. Apart from this, the expanding animal husbandry activities, along with the escalating cases of zoonotic and chronic diseases among animals, are increasing the concerns about food safety. This, along with the increasing number of commercial animal-production programs, is promoting the adoption of veterinary medicines for better diagnosis and treatment for livestock.
Moreover, the easy availability of advanced diagnostic imaging, novel therapies, nuclear and regenerative medicines, laser diagnostics, and specialized surgeries in numerous vet hospitals and clinics is bolstering the market growth. Furthermore, biomedical researchers are developing safe and effective vaccines to prevent pet diseases, which is anticipated to strengthen the market growth.
Competitive Landscape:
The competitive landscape of the industry has also been examined along with the profiles of the key players being Archer-Daniels-Midland Company, Boehringer Ingelheim GmbH, Cargill Incorporated, Ceva Sante Animale, Dechra Pharmaceuticals PLC, Elanco Animal Health Incorporated, Evonik Industries AG, Merck & Co. Inc., Neogen Corporation, Vetoquinol S.A., Virbac and Zoetis Inc.
Key Questions Answered in This Report:
How has the global veterinary medicine market performed so far and how will it perform in the coming years?
What has been the impact of COVID-19 on the global veterinary medicine market?
What are the key regional markets?
What is the breakup of the market based on the product?
What is the breakup of the market based on the animal type?
What is the breakup of the market based on the route of administration?
What is the breakup of the market based on the distribution channel?
What are the various stages in the value chain of the industry?
What are the key driving factors and challenges in the industry?
What is the structure of the global veterinary medicine market and who are the key players?
What is the degree of competition in the industry?
Key Topics Covered:
1 Preface
2 Scope and Methodology
3 Executive Summary
4 Introduction4.1 Overview4.2 Key Industry Trends
5 Global Veterinary Medicine Market5.1 Market Overview5.2 Market Performance5.3 Impact of COVID-195.4 Market Forecast
6 Market Breakup by Product6.1 Drugs6.1.1 Market Trends6.1.2 Key Segments6.1.2.1 Anti-infective6.1.2.2 Anti-inflammatory6.1.2.3 Parasiticide6.1.3 Market Forecast6.2 Vaccines6.2.1 Market Trends6.2.2 Key Segments6.2.2.1 Inactivated Vaccines6.2.2.2 Attenuated Vaccines6.2.2.3 Recombinant Vaccines6.2.3 Market Forecast6.3 Medicated Feed Additives6.3.1 Market Trends6.3.2 Key Segments6.3.2.1 Amino Acids6.3.2.2 Antibiotics6.3.3 Market Forecast
7 Market Breakup by Animal Type7.1 Production7.1.1 Market Trends7.1.2 Market Forecast7.2 Companion7.2.1 Market Trends7.2.2 Market Forecast
8 Market Breakup by Route of Administration8.1 Oral8.1.1 Market Trends8.1.2 Market Forecast8.2 Parenteral8.2.1 Market Trends8.2.2 Market Forecast8.3 Topical8.3.1 Market Trends8.3.2 Market Forecast
9 Market Breakup by Distribution Channel9.1 Veterinary Hospitals and Clinics9.1.1 Market Trends9.1.2 Market Forecast9.2 Point-of-Care Testing/In-house Testing9.2.1 Market Trends9.2.2 Market Forecast9.3 Others9.3.1 Market Trends9.3.2 Market Forecast
10 Market Breakup by Region
11 SWOT Analysis
12 Value Chain Analysis
13 Porters Five Forces Analysis
14 Price Analysis
15 Competitive Landscape15.1 Market Structure15.2 Key Players15.3 Profiles of Key Players15.3.1 Archer-Daniels-Midland Company15.3.1.1 Company Overview15.3.1.2 Product Portfolio15.3.1.3 Financials15.3.1.4 SWOT Analysis15.3.2 Boehringer Ingelheim GmbH15.3.2.1 Company Overview15.3.2.2 Product Portfolio15.3.3 Cargill Incorporated15.3.3.1 Company Overview15.3.3.2 Product Portfolio15.3.3.3 SWOT Analysis15.3.4 Ceva Sante Animale15.3.4.1 Company Overview15.3.4.2 Product Portfolio15.3.5 Dechra Pharmaceuticals PLC15.3.5.1 Company Overview15.3.5.2 Product Portfolio15.3.5.3 Financials15.3.6 Elanco Animal Health Incorporated15.3.6.1 Company Overview15.3.6.2 Product Portfolio15.3.6.3 Financials15.3.7 Evonik Industries AG15.3.7.1 Company Overview15.3.7.2 Product Portfolio15.3.7.3 Financials15.3.8 Merck & Co. Inc. 15.3.8.1 Company Overview15.3.8.2 Product Portfolio15.3.8.3 Financials15.3.9 Neogen Corporation15.3.9.1 Company Overview15.3.9.2 Product Portfolio15.3.9.3 Financials15.3.9.4 SWOT Analysis15.3.10 Vetoquinol S.A.15.3.10.1 Company Overview15.3.10.2 Product Portfolio15.3.10.3 Financials15.3.11 Virbac15.3.11.1 Company Overview15.3.11.2 Product Portfolio15.3.11.3 Financials15.3.11.4 SWOT Analysis15.3.12 Zoetis Inc.15.3.12.1 Company Overview15.3.12.2 Product Portfolio15.3.12.3 Financials15.3.12.4 SWOT Analysis
For more information about this report visit https://www.researchandmarkets.com/r/kpoq5l
Media Contact:
Research and MarketsLaura Wood, Senior Managerpress@researchandmarkets.com
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Second Sight Medical Products Announces Year Four NIH Funding of its Orion Study – Business Wire
Posted: July 19, 2022 at 2:09 am
LOS ANGELES--(BUSINESS WIRE)--Second Sight Medical Products, Inc. (NASDAQ: EYES) (the Company or Second Sight), a leading developer of implantable visual prostheses that are intended to create an artificial form of useful vision for blind individuals, today announced that the Company received notice from the National Institutes of Health (NIH) of the release of year four funding for its Early Feasibility Clinical Trial of a Visual Cortical Prosthesis (the Orion Trial), grant 5UH3NS103442. The NIH released $1.1 million of the $6.4 million planned five-year grant. The Company uses the funds primarily to pay UCLA and Baylor College of Medicine to conduct the Orion Trial. The funding supports continuation of this important research and testing of the Orion Visual Cortical Prosthesis.
About the Orion Visual Cortical Prosthesis System
Leveraging Second Sights 20 years of experience in neuromodulation for vision, the Orion Visual Cortical Prosthesis System (Orion) is an implanted cortical stimulation device intended to provide useful artificial vision to individuals who are blind due to a wide range of causes, including glaucoma, diabetic retinopathy, optic nerve injury or disease, and eye injury. Orion is intended to convert images captured by a miniature video camera mounted on glasses into a series of small electrical pulses. The device is designed to bypass diseased or injured eye anatomy and to transmit these electrical pulses wirelessly to an array of electrodes implanted on the surface of the brains visual cortex, where it is intended to provide the perception of patterns of light. An early feasibility study of the Orion is currently underway at the Ronald Reagan UCLA Medical Center in Los Angeles and the Baylor College of Medicine in Houston. No peer-reviewed data is available yet for the Orion system.
About Second Sight Medical Products, Inc.
Second Sight Medical Products, Inc. (Nasdaq: EYES) develops implantable visual prostheses that are intended to deliver useful artificial vision to blind individuals. A recognized global leader in neuromodulation devices for blindness, the Company is committed to developing new technologies to treat the broadest population of sight-impaired individuals. The Companys headquarters are in Los Angeles, California. More information is available at secondsight.com. On February 4, 2022, Second Sight entered into a merger agreement with Nano Precision Medical, Inc. (NPM), and, following approval by shareholders of the Company, anticipates concluding the merger in August 2022.
Safe Harbor
This press release contains certain forward-looking statements within the meaning of the safe harbor provisions of the US Private Securities Litigation Reform Act of 1995. Forward-looking statements can be identified by words such as: target, believe, expect, will, may, anticipate, estimate, would, positioned, future, intended and other similar expressions that predict or indicate future events or trends or that are not statements of historical matters. Examples of forward-looking statements include, among others, statements made in this press release regarding the amount of NIH grant proceeds expected to be received. Forward-looking statements are neither historical facts nor assurances of future performance. Instead, they are based only on Second Sights current beliefs, expectations and assumptions. Because forward-looking statements relate to the future, they are subject to inherent uncertainties, risks and changes in circumstances that are difficult to predict and many of which are outside of our control. Actual results and outcomes may differ materially from those indicated in the forward-looking statements. Therefore, you should not rely on any of these forward-looking statements. Important factors that could cause actual results and outcomes to differ materially from those indicated in the forward-looking statements include, among others, the following: (1) legal claims or proceedings relating to Second Sights termination of the Memorandum of Understanding with Pixium Vision and costs relating thereto; (2) changes in applicable laws or regulations; (3) the possibility that Second Sight may be adversely affected by other economic, business, and/or competitive factors; (4) the impact of COVID-19 on Second Sights business; (5) the possibility that shareholders of the Company may not approve the merger with NPM or that the merger may not be completed for any other reason; and (6) various other risks and uncertainties. Some of these risks and uncertainties may in the future be amplified by the COVID-19 outbreak, including subvariants thereof and there may be additional risks that Second Sight considers immaterial or which are unknown. A further list and description of risks and uncertainties can be found in Second Sights Annual Report on Form 10-K filed on March 29, 2022, and in the Companys Forms 10-K/A filed on May 2, 2022, S-4 filed on May 13, 2022, and 10-Q filed on May 16, 2022, and as thereafter amended. Any forward-looking statement made by us in this press release is based only on information currently available to Second Sight and speaks only as of the date on which it is made. Second Sight undertakes no obligation to publicly update any forward-looking statement, whether written or oral, that may be made from time to time, whether as a result of new information, future developments or otherwise, except as required by law.
Additional Information and Where to Find It
This communication, among other things, relates to a proposed business combination of the Company and NPM. The Company filed the registration statement on Form S-4 with the Securities and Exchange Commission (the SEC), which included a document that serves as a prospectus and proxy statement of the Company. The SEC declared the registration statement effective on June 24, 2022, and the proxy statement/prospectus was first mailed to shareholders of the Company on or about June 29, 2022. The proxy statement/prospectus described above contains important information about the Company, NPM, proposed merger, and related matters. This communication is not a substitute for the proxy statement/prospectus described above. Investors and securityholders are urged to carefully read the proxy statement/prospectus and all other relevant documents filed by the Company with the SEC because they contain important information about the merger and related matters. All documents are available free of charge at the SECs website (www.sec.gov). You may also obtain these documents by contacting Companys Investor Relations department at investors@secondsight.com.
Participants of Solicitation
The Company and its respective directors and executive officers may be deemed to be participants in any solicitation of proxies in connection with the proposed merger. Information about the Companys directors and executive officers is available in the Companys Annual Report on Form 10-K, as amended, for the fiscal year ended December 31, 2021. Other information regarding the participants in the proxy solicitation and a description of their direct and indirect interests, by security holdings or otherwise, is contained in the proxy statement/prospectus and all other relevant materials filed with the SEC regarding the proposed merger when they become available. This document is available from the Company free of charge as described in the preceding paragraph.
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Columbia Business School and Columbia Engineering to Offer New "Dual MBA/Executive MS in Engineering and Applied Science" Program – Yahoo…
Posted: July 19, 2022 at 2:09 am
20-month program to provide students with critical skill set to meet evolving business demands
NEW YORK, July 18, 2022 /PRNewswire/ -- As part of a commitment to prepare the business leaders of tomorrow, Columbia Business School and Columbia University's School of Engineering and Applied Science will offer a new dual-degree program that pairs the foundational skill sets of business with those of engineering. Students in the 20-month program will receive two degrees: a Master of Business Administration and an Executive Master of Science in Engineering and Applied Science. The program will officially launch in September 2023 and interested students can beginapplying now.
Designed to meet the evolving needs of leaders in technology, product managers, entrepreneurs, and other roles associated with technology and business, the Dual MBA/Executive MS in Engineering and Applied Science curriculumwill cover core engineering, areas of "tough tech," and applied science foundations, as well as essential business courses in leadership, strategy, finance, economics, and marketing. Students will take courses with both Columbia Business School and Columbia Engineering faculty, spend a summer pursuing an entrepreneurial venture or interning at a technology company, and complete a capstone project.
"Today's business challenges are multidisciplinary, and their solutions often lean on technological innovations. Students need, on one hand, a broad exposure to and understanding of how technology and engineering breakthroughs are shaping our lives today and the world of tomorrow. And, on the other hand, they need a deep understanding of business and, importantly, how to manage and lead in this dynamic environment," said Columbia Business SchoolDean Costis Maglaras, the David and Lyn Silfen Professor of Business. "In this competitive marketplace, Columbia's new MBAxMS: Engineering & Applied Science equips students with both the management skills and the science and technology core that enables them to move seamlessly from the classroom to product development to large-scale innovation and ultimately help create and grow companies and drive change."
The MBAxMS: Engineering & Applied Science core curriculum will focus on the creative application of technology and will include a variety of new and existing courses, including Digital Disruption & Tech Transfer, Business Analytics, Human-Centered Design and Innovation, and more. Students will also choose from an extensive array of electives designed to stimulate innovation, strengthen analytical skills, and bolster critical knowledge for their specific entrepreneurial or enterprise path.
"Technology, data, and analytics are transforming every aspect of modern businesses, especially those prized by the ambitious and entrepreneurial students who come to Columbia University," said Columbia Engineering Dean Shih-Fu Chang, the Morris A. and Alma Schapiro Professor of Engineering. "We recognize how important it is to provide students with broad exposures to emerging technology breakthroughs, the comprehensive training of business leadership skills, the unique experience in applying the human-centric design approach to innovative products and solutions, and importantly the ability to apply these unique skills in confronting major challenges facing our society and business world today. We look forward to partnering with Columbia Business School to launch an unprecedented program that can give our students a major boost."
The dual degree program, which is based in New York City, provides students with unmatched access and opportunities to work with and learn from the world's leaders in business, technology, data, analytics, and more. This includes opportunities to learn from guest speakers, meet with in-house mentors, and pursue internship opportunities that extend beyond the summer months. With one of the largest tech and entrepreneurial ecosystems in the country, the NYC location provides a unique, one-of-a-kind experience for the Dual MBA/Executive MS in Engineering and Applied Science students and graduates.
To learn more about the program, please visit https://academics.gsb.columbia.edu/mbaxms.
About Columbia Business SchoolColumbia Business School is the only world-class, Ivy League business school that delivers a learning experience where academic excellence meets with real-time exposure to the pulse of global business. The thought leadership of the School's faculty and staff members, combined with the accomplishments of its distinguished alumni and position in the center of global business, means that the School's efforts have an immediate, measurable impact on the forces shaping business every day. To learn more about Columbia Business School's position at the very center of business, please visitwww.gsb.columbia.edu.
About Columbia Engineering Columbia Engineering, based in New York City, is one of the top engineering schools in the U.S. and one of the oldest in the nation. Also known as The Fu Foundation School of Engineering and Applied Science, the School expands knowledge and advances technology through the pioneering research of its more than 250 faculty, while educating undergraduate and graduate students in a collaborative environment to become leaders informed by a firm foundation in engineering. The School's faculty are at the center of the University's cross-disciplinary research, contributing to the Data Science Institute, Earth Institute, Zuckerman Mind Brain Behavior Institute, Precision Medicine Initiative, and the Columbia Nano Initiative. Guided by its strategic vision, "Columbia Engineering for Humanity," the School aims to translate ideas into innovations that foster a sustainable, healthy, secure, connected, and creative humanity. To learn more about Columbia Engineering, please visit engineering.columbia.edu.
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Promising solution to fatal genetic-disorder complications discovered by University professor and Ph.D. candidate – Nevada Today
Posted: July 19, 2022 at 2:07 am
Affecting one in 5,000 male births worldwide, Duchenne Muscular Dystrophy (DMD) is a fatal genetic disorder that currently doesnt have a cure, but published research conducted at the University of Nevada, Reno School of Medicine shows promise and may lead to the eventual development of a new molecular therapeutic.
The latest, significant research finding, published in Human Molecular Genetics, February 2022, involves the small-molecule sunitinib which has been shown to mitigate DMD-related skeletal muscle disease in a number of ways.
As patients with DMD grow older, muscular dystrophy worsens, causing respiratory and cardiac muscle failure resulting in premature death. There are no effective treatments to prevent DMD-related cardiac failure, however continued research in the lab of UNR Med Professor of Pharmacology Dean Burkin is pointing to protein and molecular-based solutions, including sunitinib which is already FDA approved and used in cancer treatments.
Burkin conducted the latest research with Ph.D. student Ariany Oliveira-Santos. Based on a mouse model, they found that sunitinib improved major negative symptoms that stem from DMD, such as cardiac muscle damage, without depressing the immune system completely. Oliveira-Santos was lead author on the published results. The study was supported by a grant from the Muscular Dystrophy Association and the National Institutes of Health.
Burkins lab focuses mainly on studying two key proteins 71 integrinand laminin and understanding the role they play in muscle development and disease. The lab primarily studies two muscle-damaging diseases: DMD and Laminin-2 related congenital muscular dystrophy (LAMA2-CMD).
Were interested in the biology of the 71 integrin, that's really the central focus of [our research], Burkin said. But we also have other big interests in these muscle diseases where the integrin [protein] is normally found.
Burkin explains that through this translational research, which he also calls the lab bench to bedside approach, researchers attempt to understand the biology of a system as much as possible, and then continue through the development steps that lead to therapeutic treatments.
Patients with DMD lack dystrophin which causes progressive muscle degeneration and weakness. This means the more these muscles are used, the more damage occurs. While there are repair cells in muscles, these cells eventually tire out. Burkin and Oliveira-Santos noted that the heart, an organ being used all the time, does not have this repair system, making the damage severe in cardiac muscles as well. Currently some therapeutic approaches have been beneficial for skeletal muscles but not for the heart; therefore, its important to have a drug or treatment that can target and be beneficial to skeletal and cardiac muscle at the same time, Oliveira-Santos explained.
We looked to the electrical and mechanical function of the heart and both were improved, Oliveira-Santos said. Sunitinib helped the cardiac function [and reduced] cardiac damage, and inflammation. I don't think theres really many drugs out there that do that right now.
Oliveira-Santos remembers wanting to be a scientist as early as eight years old. She went on to earn degrees in Brazil, including a bachelors in biomedicine and a masters in the scientific fields of immunology and pharmacology as they relate to transplant rejection. While earning her masters degree, Burkin was invited to Brazil by Oliveira-Santoss supervisor to give a talk, and the two met in-person and discussed her masters project. At the time, they were studying the same molecule, but in different models, so Oliveira-Santos had read some of Burkins papers.
Oliveira-Santos had always been interested in the physiology and pathology of disease and thought it would be a great area to study for a doctoral degree. She knew Burkin was working in this field, so about five years after their in-person meeting, Oliveira-Santos reached out to Burkin. He told her about an open position in his lab for a Ph.D. student, and their project of understanding the role of an FDA-approved small molecule for the treatment of DMD cardiomyopathy. She felt this project was a good match for what she was looking for and joined the lab in January 2019.
Oliveira-Santos said the mentorship and support shes received from Burkin and the rest of the lab has been invaluable.
Dean is always available to discuss and very happy to help [the lab members] with everything we need, Oliveira-Santos said. Everyone had an important opinion about the project and that was essential for the projects success.
While working in science oftentimes can come with struggles, Oliveira-Santos expressed how much these experiences have taught her.
Being in science is a big challenge, because you have to learn how to deal with problems all the time, she said. There are more failures than success [so] it teaches you how to deal with failure. Failure is normal. You just need to try to find a way around to get a solution.
Oliveira-Santos is set to finish her Ph.D. in Cellular and Molecular Pharmacology & Physiology in the fall 2022.
When I bring a student to the lab, I say I can supply everything but enthusiasm. And that's one thing that Ariany brings in abundance, Burkin said. I'm putting my students in contact with other principal investigators that I know to try and make sure that the next level on their career is achieved. She can go anywhere right now and move forward. The world is her oyster.
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