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Monthly Archives: April 2022
The Global Circulating Tumor Cells (CTC) Market Will Grow to USD 18.41 Billion by 2026, at a CAGR of 14.1% – GlobeNewswire
Posted: April 6, 2022 at 2:43 am
Dublin, April 05, 2022 (GLOBE NEWSWIRE) -- The "Global Circulating Tumor Cells (CTC) Market (2021-2026) by Technology, Application, Product, Specimen, End-User, and Geography, Competitive Analysis and the Impact of Covid-19 with Ansoff Analysis" report has been added to ResearchAndMarkets.com's offering.
The Global Circulating Tumor Cells (CTC) Market is estimated to be USD 9.52 Bn in 2021 and is expected to reach USD 18.41 Bn by 2026, growing at a CAGR of 14.1%.
Key factors such as the growing incidence of cancer followed by the increasing potential of CTCs in diagnosis and treatment have been a prominent driver for the Global Circulating Tumor Cells (CTC) Market.
Similarly, the shifting preference towards minimally invasive diagnostic methods and higher awareness about cancer has led to preventive initiatives taken by individuals in demand for preventive medicines.
However, factors such as lack of awareness and technical difficulties in detection are likely to restrain the market growth. Moreover, stringent government regulations and reluctance to adopt novel CTC technologies are posing to cause significant challenges for the market growth.
Market Segmentation
Company Profiles
Some of the companies covered in this report are Aviva Biosciences, Advanced Cell Diagnostics, Biocept, LungLife AI, Creatv Micro Tech, Miltenyi Biotec, Menarini Silicon Biosystems, Precision for Medicine, Qiagen, etc.
Key Topics Covered:
1 Report Description
2 Research Methodology
3 Executive Summary3.1 Introduction3.2 Market Size and Segmentation3.3 Market Outlook
4 Market Influencers4.1 Drivers4.1.1 Growing Incidence of Cancer and Potential Of CTC In Diagnosis and Treatment4.1.2 Increasing Demand for Preventive Medicine and Companion Diagnostics4.1.3 Increasing Preference for Non-Invasive Methods Cancer Diagnosis4.2 Restraints4.2.1 Stringent Government Regulations4.2.2 Technical Difficulties in Detection4.2.3 High Variability Among Patient Samples and Assays in Immuno-Oncology Trials4.3 Opportunities4.3.1 Increasing R&D Activities in CTC Analysis and Detection Practices4.3.2 Advancements in Chip Technology4.3.3 Emergence of New Single-Cell Technologies4.4 Challenges4.4.1 Lack Of Awareness4.4.2 Reluctance For the Adoption of Novel CTC Technologies
5 Market Analysis5.1 Regulatory Scenario5.2 Porter's Five Forces Analysis5.3 Impact of COVID-195.4 Ansoff Matrix Analysis
6 Global Circulating Tumor Cells (CTC) Market, By Technology6.1 Introduction6.2 CTC Enrichment6.2.1 Immunocapture/Label-Based6.2.1.1 Positive Selection6.2.1.2 Negative Selection6.2.2 Size-Based Separation/Label-Free6.2.2.1 Membrane-Based Size Separation (Label-Free)6.2.2.2 Microfluidic-Based Size Separation (Label-Free)6.2.3 Density-Based Separation (Label-Free)6.2.4 Combined Methods (Label-Free)6.3 CTC Direct Detection6.3.1 Microscopy6.3.2 SERS6.3.3 Immunocytochemical Technology6.3.4 Molecular (RNA)-Based Technology6.3.5 Others6.4 CTC Analysis & Downstream Assays
7 Global Circulating Tumor Cells (CTC) Market, By Application7.1 Introduction7.2 Multiple Chromosome Abnormalities7.3 RNA Profiling7.4 Protein Expression7.5 Cellular Communication
8 Global Circulating Tumor Cells (CTC) Market, By Product8.1 Introduction8.2 Devices or Systems8.3 Kits & Reagents8.4 Blood Collection Tubes
9 Global Circulating Tumor Cells (CTC) Market, By Specimen9.1 Introduction9.2 Blood9.3 Bone Marrow9.4 Other Body Fluids
10 Global Circulating Tumor Cells (CTC) Market, By End User10.1 Introduction10.2 Research & Academic Institutes10.3 Hospitals/ Clinics10.4 Diagnostic Centers
11 Global Circulating Tumor Cells (CTC) Market, By Geography11.1 Introduction
12 Competitive Landscape12.1 Competitive Quadrant12.2 Market Share Analysis12.3 Strategic Initiatives
13 Company Profiles
For more information about this report visit https://www.researchandmarkets.com/r/9nffnt
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The Global Circulating Tumor Cells (CTC) Market Will Grow to USD 18.41 Billion by 2026, at a CAGR of 14.1% - GlobeNewswire
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Dr. Herbst on the Evolution of Targeted Therapies in NSCLC – OncLive
Posted: April 6, 2022 at 2:43 am
Roy S. Herbst, MD, PhD, discusses the evolving treatment landscape of targeted therapies in nonsmall cell lung cancer.
Roy S. Herbst, MD, PhD, ensign professor of medicine (medical oncology), professor of pharmacology, Yale School of Medicine, director, the Center for Thoracic Cancers, chief, Medical Oncology, associate cancer center director, Translational Science, Yale Cancer Center, Smilow Cancer Hospital, discusses the evolving treatment landscape of targeted therapies in nonsmall cell lung cancer (NSCLC).
Multiple FDA approvals highlighted a busy year of action in the lung cancer space in 2021, Herbst says. The approval of osimertinib (Tagrisso) brought targeted therapy to the adjuvant setting for patients with stage I, II, and III NSCLC harboring EGFR mutations, Herbst explains. Moreover, the atezolizumab (Tecentriq) was approved for adjuvant treatment in patients with stage II to IIIA NSCLC whose tumors have PD-L1 expression on 1% or moreof tumor cells, Herbst adds.
These approvals have helped bring some of the best drugs and targeted therapies into earlier settings, Herbst continues. The approval of new targeted therapies, such as amivantamab-vmjw (Rybrevant) as the first treatment for adult patients with NSCLC harboring EGFR exon 20 insertion mutations, also demonstrate how the landscape has shifted, Hebst concludes.
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Dr. Herbst on the Evolution of Targeted Therapies in NSCLC - OncLive
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UBC Medicine researchers awarded nearly $1 million from New Frontiers in Research Fund – UBC Faculty of Medicine – UBC Faculty of Medicine
Posted: April 6, 2022 at 2:43 am
By Digital Comms | April 4, 2022
Drs. Joanne Matsubara, Nika Shakiba, Ying Wang and Michael Kobor.
Four researchers in UBCs faculty of medicine are leading projects that received nearly $1 million from the Government of Canadas New Frontiers in Research Fund (NFRF).
They are amongst twelve UBC-led projects that were awarded over $2.8m through the NFRFs 2021 Exploration and Special Call Streams.
The Honourable Franois-Philippe Champagne, Minister of Innovation, Science and Industry, and the Honourable Jean-Yves Duclos, Minister of Health, announced a total of over $45 million in support for research projects through the NFRF. This combined investment is supporting 751 researchers, including 245 early career researchers. The projects were part of two competitions under the banner of the NFRF: the 2021 Exploration competition; and the NFRF special call on innovative approaches to research in the pandemic context.
Launched in 2018, the NFRF funds high risk-high reward, interdisciplinary, and transformative research led by Canadian researchers. The NFRF is designed to support world-leading innovation and enhance Canadas competitiveness and expertise in the global, knowledge-based economy.
The faculty of medicine researchers are:
Dr. Joanne MatsubaraProfessor, department of ophthalmology & visual sciencesProject: In Vivo Imaging for Investigating Neurodegenerative Diseases of the Brain and Eye Cell simulator: a computer-driven approach to genetically programming cells
$250,000 Exploration stream
Dr. Nika ShakibaAssistant professor, school of biomedical engineeringProject: Cell simulator: a computer-driven approach to genetically programming cells
$250,000 Exploration stream
Dr. Ying WangAssistant professor, department of pathology and laboratory medicineProject: Beyond morphology: Convert disease-related gene networks to pixels in digital pathology to solve the puzzle of vulnerable plaques that lead to cardiovascular events
$250,000 Exploration stream
Dr. Michael KoborProfessor, department of medical geneticsProject: Developing an integrated, innovative platform for retrospectively quantifying the prenatal and early child exposome using deciduous teeth
$237,708 Special call
Posted in Cell Medicine
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Right to Try 2.0: Ahwatukee family pushes for proposed law after getting medical treatment abroad – FOX 10 News Phoenix
Posted: April 6, 2022 at 2:42 am
Right to Try 2.0: Arizona family pushes for proposed law after getting medical treatment abroad
An Ahwatukee family is pushing for a proposed law called 'Right to Try for Individual Treatments' after they had to travel abroad to get medical care for their daughter who suffers from a rare disease. FOX 10's Stephanie Olmo reports.
AHWATUKEE, Ariz. - Life for the Rileys has been nothing short of challenging these past two years. Having to travel to Italy to get a lifesaving treatment for their daughter, but they're hoping to soon get help here at home.
"Everything was upside down in the world, and then we had this personal situation happening," said Kendra Riley, who has three daughters. Two of them, Olivia and Keira, have a rare genetic disease called metachromatic leukodystrophy.
"It affects the mileage (blank) of the brain, it affects the nerves so really quickly our daughter Olivia lost her ability to walk, talk, she can no longer eat on her own and the average life span is age 6 ."
Sadly, there is no cure for people who are symptomatic like Olivia, but 2-year-old Keira, who was a newborn at the time she was diagnosed, there was a chance as she was not showing symptoms. But the only way to get specialized treatment to save her life was to move the family to Milan, Italy for six months during the COVID-19 pandemic.
"There were appointments like the process of Leukapheresis where you pull out the stem cells in order to take them to the lab fix them essentially and put them back into her body but after Leukapheresis she has to go to chemo for 4 to 5 days after the chemo they put the renewed stem cells back in her body just through an IV."
Keira received an individualized treatment that FDA regulations block access to in the states. Kendra and others are trying to change that and through their efforts, Arizona is now considering the Right to Try for Individualized Treatments.
"These are tailored made for the individual. Individualized treatments in the states has all but stifled, it is difficult to get these yet in other countries they are really popular. We see that this truly is the next wave of medicine," said Jenna Bentley, Director of Government Affairs for the Goldwater Institute.
If the new piece of legislation becomes law in Arizona, no family will have to go through what the Rileys have endured. The bill is currently awaiting a floor vote in the Arizona House.
Online: https://righttotry.org
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Right to Try 2.0: Ahwatukee family pushes for proposed law after getting medical treatment abroad - FOX 10 News Phoenix
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Does hormone replacement therapy (HRT) increase cancer …
Posted: April 6, 2022 at 2:41 am
What is HRT?
HRT is a treatment that can reduce symptoms of the menopauseby changing hormone levels in the body. Hormones are chemical messengers. They can affect things like growth, fertility and our mood.
During the menopause, the ovaries start to produce less of the hormone oestrogen. This means some people may experience menopausal symptoms, such as hot flushes and mood changes. For some, these symptoms are very uncomfortable, and HRT can help to reduce them.
Trans men and women may also use hormone therapy. But there isnt yet enough research about cancer risk associated with this. This webpage only covers menopausal HRT and cancer risk.
The main types of HRT are:
Some other forms of HRT are less commonly prescribed, such as tibolone (external link). Your GP can give you more information about the different types if you think HRT might help you.
Risk from HRT depends on many different things. This includes the type of HRT, when people start taking it, how long they take it for, age, and general health. And the benefits of taking HRT will vary from person to person too.
Everyones different, so talk to your GP about your options.
Its also important to remember that there are other things that affect cancer risk more than HRT. For example, you can reduce your cancer risk by stopping smoking, keeping a healthy weight, and drinking less alcohol.
Most types of HRT increase the risk of breast cancer. But the risk is higher for those using combined HRT, which uses bothoestrogen and progestogen.
Vaginal oestrogens are not linked to an increased risk of breast cancer, whereas tibolone is.
Taking HRT for 1 year or less only slightly increases breast cancer risk. However, the longer you take HRT the greater the risks are, and the longer they last.
The risk of breast cancer due to HRT can also vary from person to person. Things such as what age you are when you first start taking HRT, other medicines you may be taking, and your general health can impact the risk.
People who begin HRT before or soon after the menopause may have a bigger risk than those who start HRT later.
Yes, both oestrogen-only and combined HRT slightly increase the risk of ovarian cancer. But when HRT is stopped, the risk starts to go back to what it would have been if HRT wasnt taken.
Its not yet clear if theres any link between ovarian cancer and tibolone.
The risk of womb cancer depends on the type of HRT.
Oestrogen-only HRT increases the risk of womb cancer. The longer this type of HRT is used, the bigger the risk. Thats why oestrogen-only HRT is usually only offered to those who have had their womb removed (a hysterectomy) as they have no risk of womb cancer to begin with.
Combined HRT can reduce womb cancer risk. But combined treatment causes the biggest increase in breast cancer risk. So, its important to talk to your doctor about the balance of possible benefits and risks for you.
Similar to oestrogen-only HRT, tibolone also increases the risk of womb cancer.
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Hormone Replacement Therapy Market Size estimated to exhibit at a 5.2% CAGR, Future Business Opportunities through 2028 | Abbott, Mylan N.V., Merck…
Posted: April 6, 2022 at 2:41 am
Coherent Market Insights has released a new research study on the Hormone Replacement Therapy Market which aims to provide a thorough examination of the factors influencing global business introduction and outlook. The Global Hormone Replacement Therapy Market Report detailed information and overview highlight the most recent trends in various regions. Leading market participants will benefit from the trading insights provided in this report. The Hormone Replacement Therapy Market research report is an intelligence report that includes precise and valuable data on market size, development countries, market share, and revenue forecasts through 2028. It also provides information on the markets development and capabilities.
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The Global Hormone Replacement Therapy Market Analysis Report provides a detailed analysis of the market size of various segments and countries in previous years, as well as forecasts for the coming years. The Hormone Replacement Therapy Market report presents a detailed competitive landscape of the global market. The market dynamics, drivers, and segmentation by application, type, region, and manufacturer are all discussed in this report. With respect to the regions and countries covered in the report, this Hormone Replacement Therapy Market report provides both qualitative and quantitative aspects of the industry.
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Health center to provide gender-affirming care on campus by fall 2022 – The Collegian – The Collegian
Posted: April 6, 2022 at 2:41 am
Students and staff have advocated for over a year for the Student Health and Counseling Center (SHCC) to offer gender-affirming care (GAC) for transgender and nonbinary students. In response to their efforts, the SHCC now plans to incorporate GAC by fall 2022.
Jordan Fitzpatrick, a first-year graduate student in the sasters in social work program, planned an informational meeting for students via Zoom on April 1 in response to students and staff being met with reluctance or refusal by the health center to incorporate GAC.
GAC includes counseling support as well as medical support, such as providing hormone replacement therapy (HRT) on campus, for transgender and nonbinary students.
Fitzpatrick was expecting to involve students in advocating for the inclusion of GAC. Instead, he was able to present attendees with the SHCCs plan for GAC, with both counseling and medical support, including having an experienced physician [to] provide HRT services on-site, according to the plan.
The plan states its primary goal is to provide a sustainable programmatic operational plan supporting our students with gender-affirming care.
The plan includes counseling and psychological services, medical services, an improved website with updated resources, a GAC care group, additional SHCC positions to hire for and a Cross-Cultural and Gender Center (CCGC) student liaison, all by the start of the fall 2022 term.
Fitzpatrick, who also uses the pronoun they, explained that offering HRT on campus rather than being referred out is particularly important due to the limited options for GAC within the Central Valley.
Most people have to travel outside the Central Valley in order to receive basic care. Often, when transgender and gender nonconforming people do seek medical care in the Central Valley, they face doctors who are not informed on how to care for [them], or refuse care, or are outright hostile to [them], they said.
Fitzpatrick noted that these students, who paid for services at the health center as part of their tuition just like other students, should be able to receive this care and not be denied hormones due to gender.
During the meeting, Fobear explained that the refusal to offer GAC, and in particular HRT, is an equity issue.
Fobear noted that currently two women can go to the SHCC, one cisgender and one transgender, and one can be given hormonal treatment in the form of birth control, and one can be denied hormonal treatment in the form of HRT, and called this an instance of discrimination.
Its really important that we make sure that this actually happens and we hold them accountable, and that we have a way to make sure that it stays in place, Fitzpatrick said.
Fobear and Fitzpatrick assured attendees that despite the promise to incorporate GAC, there was more to be done, and that the process to get there hadnt been simple, either.
The need to begin offering GAC care arose about a year and a half ago before the meeting, according to Fobear, when John Beynon from the English department spoke to the Fresno State LGBT+ Allies Network on the need for and the possibility of providing GAC at the SHCC, which he had seen being done at other CSU campuses, such as Chico State and Cal Poly.
Concerned campus members formed a GAC subcommittee focused on bringing GAC to campus, and have been in talks for the last year on how to begin offering this care to students as well as protecting transgender and nonbinary students seeking GAC from discrimination, Fobear said.
[The talks] intensified within the past four months, where the biggest sticking issue was about providing HRT on campus. There seem to have been a lot of maybe reticence, maybe roadblocks, but basically no sort of commitment into providing this, Fobear said.
Recent talks, which Fobear described as intense, showed no sign of improvement. Despite initially hesitating to involve students out of reluctance to stress out transgender and nonbinary students, Fobear said this is when she and Fitzpatrick decided to reach out.
Fitzpatrick sent out the invite to the first informational meeting for the student collective, but on March 31, the SHCC sent in its care model before the meeting even took place.
Still, due to the struggles to get to that point, attendees stressed the need to ensure accountability by the health center.
Fobear encouraged attendees to continue advocating for the need for GAC on campus and to stay involved in the process, attributing the current successes to student and facultys efforts and attention.
The logistics of ensuring accountability and making the GAC sustainable were discussed at the end of the meeting, and will continue to be specified in any upcoming meetings.
Other topics pertaining to LGBTQ+ students were discussed during the meeting, such as the possibility of turning the University Student Union into an LGBTQ+ center once the Resnick Student Union (RSU) opens. Concerns raised about gender neutral bathrooms in the RSU were settled by ASI President DAungullique Jackson, who also attendes and assured other attendess the gender neutral bathrooms would be available.
Students who are interested in attending future meetings and participating in these discussions can email Fitzpatrick at gac4fresnostate@gmail.com to be added to the mailing list and be alerted when future announcements are made.
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How to ease joint pain during the menopause – Patient.info
Posted: April 6, 2022 at 2:41 am
What causes menopause joint pain?
It may be a natural part of the female ageing process, but menopause can bring discomfort and pain in a number of ways. Learning how to manage your symptoms can make a big difference in your quality of life during this period.
From hot flushes and vaginal dryness to disturbed sleep and anxiety, there are lots of possible symptoms that may make daily activities more challenging. These noticeable changes reflect the significant change that's taking place in your body, as your sex hormone levels fluctuate and cause your ovaries to lose their reproductive function.
Ann Clare, a physiotherapist for MBST UK, explains how these changes can lead to menopause joint pain: "Oestrogen, the hormone that plays a key role in regulating your menstrual cycle, helps to decrease inflammation and keep the joints lubricated. During the menopause and perimenopause, oestrogen levels decrease and as a result, some women experience joint pain."
"Recent studies have suggested that a decrease in oestrogen not only reduces natural bone density but also affects muscle strength and tendon health. In turn, this may result in longer injury recovery times," says Kirsty Lee, senior physiotherapist and pelvic health lead at Ascenti.
Menopause joint pain can affect joints all over your body and can also result in longstanding injuries becoming more painful.
According to Lee, menopause joint pain most commonly affects the following areas:
"As oestrogen continues to decrease, joints can become more inflamed and painful, resulting in an increased risk of osteoporosis (thinning of the bone) and osteoarthritis (inflammation of the joints) developing," she adds.
When it could be osteoarthritis
Osteoarthritis is more likely to occur in people over 50 years, around the same time that many women start menopause. While joint pain and stiffness around the time of menopause doesn't always indicate osteoarthritis, it can be a symptom. Osteoarthritis joint pain is more likely to occur in the knees, hips, lower spine, fingers, and thumbs.
When it could be osteoporosis
Being over 40 and going through menopause increases your chances of rapid bone loss, which may lead to osteoporosis. Unlike menopause joint pain and osteoarthritis, you usually won't feel pain unless you break a bone. Your doctor may wish to test you for osteoporosis if you are menopausal and have had a bone breakage from a minor injury.
Back pain, and particularly lower back pain, can become a problem for many women as they go through menopause. In fact, one survey of 5,325 women found that postmenopausal women were twice as likely to report lower back pain as premenopausal women.
Your spine is made up of multiple joints, including facet joints that allow movement in your back. Decreased oestrogen results in greater inflammation of these joints and also causes your spinal (intervertebral) discs to wear down.
Menopause joint pain of the knees is also very common. This may not be surprising, given that your knee is one of your largest joints, connecting and supporting your thighbone (femur), kneecap (patella), shinbone (tibia), and calf bone (fibula). Your knees are subject to a great deal of pressure and wear throughout your life as they support a large portion of your weight.
The good news is, there are both medical and non-medical forms of pain management that are proven to significantly reduce menopause joint pain. This can start with simple routines in the home.
Home treatments include:
Your diet is hugely important in both preventing and managing health issues, and menopause joint pain is no different. "Try to eat a healthy, balanced diet that is high in fibre with lots of fruit, vegetables and wholegrain foods," advises Clare.
Eating the right foods can improve a range of menopause symptoms. The key is to consume lots of nutrients from various food groups.
The foods that most directly impact joint and bone health include:
"You should also try to avoid large quantities of saturated fats. If you are suffering from hot flushes, try to make a note of what seems to bring them on - for some people it is alcohol and for others caffeine," adds Clare.
If you experience menopause joint pain, you may be tempted to limit your movements. It may feel counter-intuitive at first, but the experts recommend staying as physically active as possible.
Lee says: "Move! Motion is lotion, and if this is managed and progressed slowly it can be an effective tool for pain management."
Why: "Unfortunately, weight gain is also a common side effect of menopause, and increased weight can have a detrimental effect on joint and muscle pain due to increased load. Therefore, weight management is a key part of managing joint pain."
What: "There are lots of forms of exercise that can help with pain as well as other menopause symptoms. An effective 'menopause friendly' programme should consist of endurance, strength/resistance, and balance exercises."
Clare says: "It is best to be as active as possible and most of all enjoy your sports."
Why: "Weight-bearing exercises will strengthen your musculoskeletal system which will help to alleviate joint aches and pains, protect brittle bones, and may prevent osteoporosis."
What:
Ivana Daniell, movement and posture expert, says: "The right choice of exercise programme can be of great support during the time of menopause, both physically and mentally. Be aware of not pushing your body too hard, especially during this delicate hormonal transition."
Why: "When the female body is pushed too hard, it goes into adrenal stress and this creates havoc in the incredibly engineered yet delicate hormonal balance."
What: "Quality of movement versus quantity is paramount. Regular and consistent exercise is better than sporadic visits to the gym that make you exhausted. Choose activities that uplift your mood and practise 2-3 times per week in addition to your daily 30-40 minute walk."
You may also use over-the-counter medicines to help reduce inflammation and painful joints. These include common painkillers and anti-inflammatory gels and medication. Your pharmacist will be able to advise.
It should also be noted that hormone replacement therapy (HRT) is widely accepted as the most effective method for managing the symptoms of menopause. By restoring the oestrogen levels you lose during menopause, there is strong evidence that HRT can ease menopause joint pain alongside a whole host of other symptoms.
There are also several menopause herbal remedies and supplements on the market. Biomedical gerontologist Dr Marios Kyriazis says that supplementation should be used alongside - and not as a substitute for - healthy lifestyle changes:
"The most effective lifestyle changes include switching to an anti-inflammatory diet, incorporating light to moderate physical activity, practising breathing and relaxation exercises on a daily basis, and improving sleep patterns. Under these conditions, herbal blends and anti-inflammatory supplements work best."
Kyriazis recommends supplementing curcumin, the active ingredient in turmeric.
Curcumin may:
"By fermenting turmeric, its curcumin content becomes more bio-available at a smaller dose and is gentler on the stomach than the usual raw turmeric with black pepper that is generally recommended," he adds.
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What’s behind the trend of women posting make-up free photos on social media? – Fox News
Posted: April 6, 2022 at 2:41 am
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What do Michelle Pfeiffer, Tyra Banks, Jennifer Aniston, Jennifer Lopez and Helen Mirren have in common?
Social media platforms dont just harm teenagers, but can be harmful to women as they age, so these women are fighting back with make-up selfies to embrace their age, according to a recent Wall Street Journalreport.
"Were also bombarded by images on our phones all the timethis five years ago, this 10 years ago," New York psychiatrist Dr. Samantha Boardman, noting, " its a reminder of the passage of time and how we do look different."
She said we should be paying more attention how social media affects women as they get older, because it makes older women feel as bad as teenagers, especially when the way a woman looks doesnt match how she is feeling.
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"I have a craving to see real faces of my age, so I dont feel so alone in aging," said model Paulina Porizkova, who is56.
MIAMI, FL - MAY 11: Paulina Porizkova attends the Sports Illustrated Swimsuit Celebrates 2019 Issue Launch at Myn-Tu on May 11, 2019, in Miami, Florida. ((Photo by John Parra/Getty Images for Sports Illustrated))
Middle age is often a time of high stress for women, because many are trying to balance careers, raise children and also care for aging parents, according to theJournal.
As more older women begin to embrace their natural look, posting make-up selfies can be empowering.
"Its satisfying to feel connected and not so alone in how you look, so I think there is a generosity in that when its authentic," saidBoardman.
She cautioned the natural look might be staged at times with products, treatments and injectables that contribute to that look, so when sometimes celebrities post the "natural" hashtag, it might be supported by ring lights, secret makeup and even a filter, per the paper.
"Often were barraged with images that we dont even know are touched up," New Yorkbased psychiatrist and dermatologist Dr. Amy Wechsler told thepaper.
Some beauty brands, like Milk, Dove and Olay, are supporting this trend, using real photos that are not retouched across a wide spectrum of ages to showcase womens beauty at their stage inlife.
But make-up free selfies arent the only remedy middle-age women are using to take care of their mental health many are resorting to antidepressants, according to the Wall StreetJournal.
Tyra Banks recalled once holding her dress together while filming 'Dancing with the Stars.' (Getty Images)
But some doctors are concerned antidepressants are being overprescribed for symptoms that may actually be attributed to menopause, which the median age in the U.S. is 51, per the newsreport.
Approximately one in five women ages 40-59 and an estimated one in four women ages 60 and older used antidepressants in the last 30 days during 2015 to 2018, compared to one in 10 for women ages 18-39, according to the most recent data from the National Center for Health Statistics.
In general women are at higher risk for depression than men, but the risk of depression is highest leading up to menopause and immediately after it. Its sometimes difficult, however, to tease out the root cause of peri-menopausal symptoms, because the imbalance of hormones during this period that are responsible for typical symptoms, such as hot flashes and night sweats, can also affect a womans mood, per theJournal.
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The most effective treatment for hot flashes and night sweats is hormone therapy with either estrogen or combined with progestogen, according to the North American Menopause Society and the American College of Obstetricians and Gynecologists.
But women are looking for alternative treatments since many are " so deathly afraid of prescribing hormones," said Dr. Stephanie Faubion, medical director of the North American Menopause Society and the director of Mayo Clinic WomensHealth.
Jennifer Aniston attends 26th Annual Screen Actors Guild Awards at The Shrine Auditorium on January 19, 2020, in Los Angeles, California. (Photo by Leon Bennett/Getty Images)
So now scientists are trying to develop anti-depressants that will target depression symptoms related to estrogen withdrawal without the side effects of hormone replacement therapy, according to Dr. Peter Schmidt, chief of the Behavioral Endocrinology branch in National Institute of Mental Health Intramural Research program.
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"While I look with wonder and awe at the women who age backwards, Id like a little more choice in representation of age. So I hope to provide a little of that for women who feel like I do, that age is coming into ones true beauty and character, and it should be celebrated, not erased," Porizkova said.
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Why so many women in middle age are on antidepressants – Mint
Posted: April 6, 2022 at 2:41 am
About one in five women ages 40 to 59 and nearly one in four women ages 60 and over used antidepressants in the last 30 days during 2015 to 2018, according to the latest data from the National Center for Health Statistics. Among women ages 18 to 39, the figure was about one in 10. Among men, 8.4% of those ages 40 to 59 and 12.8% of those 60 and older used antidepressants in the last 30 days, according to the NCHS data.
The figures are drawing increasing attention from scientists and doctors. Many are alarmed at how high depression rates were among midlife women even before the pandemic, now that the past two years have exacerbated mental-health issues for many Americans. And some doctors are also concerned that antidepressants are being overprescribed for menopausal symptoms.
In general, women have higher rates of depression than men throughout much of their lives according to scientific research. In midlife, the risk is greatest during the years leading up to menopause and right after it. The dramatic fluctuations in hormones that cause the most-commonly known symptoms of hot flashes and night sweats can wreak havoc on mood, too.
Estrogen and progesterone are fluctuating a great deal," says Lucy Hutner, a reproductive psychiatrist in New York City. Those shifts can be hard for our brain to take."
Scientists are working to understand just how hormones may drive depression, but receptors for estrogen and progesterone are found throughout the brain including in regions involving movement, cognition and mood regulation, says Hadine Joffe, a professor of psychiatry at Brigham and Womens Hospital and Harvard Medical School in Boston.
New treatments for depression in midlife women may be on the horizon. Scientists at the National Institute of Mental Health, for example, are studying a medication that acts on an estrogen receptor in the brain. The hope is that, unlike typical antidepressants, it will directly target depression symptoms related to estrogen withdrawal but without the side effects of traditional hormone therapy commonly used for menopausal symptoms, notes Peter Schmidt, chief of the Behavioral Endocrinology branch in NIMHs Intramural Research program.
Studies have found that womens risk of having an episode of major depression is two to four times higher around menopause than at other times during their lives; it is even greater for women who have a had a previous episode of depression. Menopause is defined to have occurred one year after a womans last menstrual period. The median age of menopause in the U.S. is 51.
Doctors also note that midlife is often a time of marked stress for womenand stress can increase the risk of depression. Many women are juggling careers, raising children and caring for elderly parents. You have a lot on your shoulders, and theres not a lot of room for taking time for yourself," says Dr. Hutner. Women also may be more likely to seek care for a mental-health problem than men, which may lead to higher rates of diagnosis and treatment.
Valerie DeMartin, 59 years old, says she fell into a depression in 2020. She was dealing with sleep problems, the stress of the pandemic and a move with two teenagers from the familys longtime home in California to Texas. An avid exerciser, she says she was also feeling sad to see her body changing in ways she felt she couldnt control.
I went through a life-altering move, my kids were angry with me, dealing with middle age and Covid and my body changing," says Ms. DeMartin, who works in home remodeling in Frisco, Texas.
Ms. DeMartin says she didnt seek therapy or take antidepressant medication. She says she has coped by reaching out to friends and staying busy with work. Shes also planning to try hormone-replacement therapy. Hopefully Ill have a little more energy and sleep better," she says.
Researchers at NIMH who have been following 90 women since 1988 have found that the incidence of womens midlife depression is concentrated in the two years before and after the last menstrual period, says Dr. Schmidt. The quality of womens midlife depression is distinct, too, Dr. Schmidt says, in that it often involves intense anxiety, irritability and sleep problems along with the more typical sadness and loss of pleasure in once-enjoyed activities.
Doctors speculate that antidepressant use among middle-aged women is being driven in part by the reluctance of womenand many of their physiciansin recent decades to use hormone-replacement therapy for menopausal symptoms. In 2002, a large study, the Womens Health Initiative, was stopped after women taking hormone therapy had an increased risk of breast cancer, heart attacks and strokes. Later analyses found that the risks were largely concentrated among women who were older when they started hormone therapy. For women in their 50s, hormone therapy actually reduced the risk of heart disease and death from any cause.
Hormone therapy, either estrogen alone or combined with a progestogen, is the most effective treatment for hot flashes and night sweats, according to the North American Menopause Society and the American College of Obstetricians and Gynecologists. Some research has found that it can also improve mood.
Still, many women and doctors are looking for alternatives. People are so deathly afraid of prescribing hormones," says Stephanie Faubion, medical director of the North American Menopause Society and the director of Mayo Clinic Womens Health. A lot of women, unfortunately, who are going to their doctors because of hot flashes and night sweats are getting slapped on antidepressants."
Research has shown that some antidepressants can ease hot flashes and night sweats. But Dr. Faubion says they are much less effective than hormones. The even higher rates of antidepressant use among women 60 and over may partly result from women being put on them when theyre younger, during this earlier period of mental-health vulnerability, and then being left on them by default, says Dr. Hutner.
This story has been published from a wire agency feed without modifications to the text
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