Monthly Archives: July 2015

Sickle cell disease | University of Maryland Medical Center

Posted: July 2, 2015 at 2:42 am

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An in-depth report on the causes, diagnosis, and treatment of sickle cell disease.

Sickle cell anemia

What is Sickle Cell Disease?

Sickle cell disease is an inherited blood disorder in which the body produces abnormally shaped red blood cells. In sickle cell disease, the hemoglobin in red blood cells clumps together. This causes red blood cells to become stiff and C-shaped. These sickle cells block blood and oxygen flow in blood vessels. Sickle cells break down more rapidly than normal red blood cells, which results in anemia.

What Causes Sickle Cell Disease?

Sickle cell disease is a genetic disorder. People who have sickle cell disease are born with two sickle cell genes, one from each parent. If one normal hemoglobin gene and one sickle cell gene are inherited, a person will have sickle cell trait. People who have sickle cell trait do not develop sickle cell disease, but they are carriers who can pass the abnormal gene on to their children.

Complications of Sickle Cell Disease

Sickle cell disease can block the flow of blood in arteries in many parts of the body, causing many complications. The hallmark of sickle cell disease is the sickle cell crisis, which causes sudden attacks of severe pain. Acute chest syndrome, which is triggered by an infection or by blockage of blood vessels in the lungs, is another common and serious occurrence. Additional medical complications include:

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Radiation Therapy for Cancer – National Cancer Institute

Posted: July 2, 2015 at 2:42 am

What is radiation therapy?

Radiation therapy uses high-energy radiation to shrink tumors and kill cancer cells (1). X-rays, gamma rays, and charged particles are types of radiation used for cancer treatment.

The radiation may be delivered by a machine outside the body (external-beam radiation therapy), or it may come from radioactive material placed in the body near cancer cells (internal radiation therapy, also called brachytherapy).

Systemic radiation therapy uses radioactive substances, such as radioactive iodine, that travel in the blood to kill cancer cells.

About half of all cancer patients receive some type of radiation therapy sometime during the course of their treatment.

How does radiation therapy kill cancer cells?

Radiation therapy kills cancer cells by damaging their DNA (the molecules inside cells that carry genetic information and pass it from one generation to the next) (1). Radiation therapy can either damage DNA directly or create charged particles (free radicals) within the cells that can in turn damage the DNA.

Cancer cells whose DNA is damaged beyond repair stop dividing or die. When the damaged cells die, they are broken down and eliminated by the bodys natural processes.

Does radiation therapy kill only cancer cells?

No, radiation therapy can also damage normal cells, leading to side effects.

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What is Biotechnology? | BIO

Posted: July 2, 2015 at 2:42 am

At its simplest, biotechnology is technology based on biology - biotechnology harnesses cellular and biomolecular processes to develop technologies and products that help improve our lives and the health of our planet. We have used the biological processes of microorganisms for more than 6,000 years to make useful food products, such as bread and cheese, and to preserve dairy products.

Modern biotechnology provides breakthrough products and technologies to combat debilitating and rare diseases, reduce our environmental footprint, feed the hungry, use less and cleaner energy, and have safer, cleaner and more efficient industrial manufacturing processes.

Currently, there are more than 250 biotechnology health care products and vaccines available to patients, many for previously untreatable diseases. More than 18 million farmers around the world use agricultural biotechnology to increase yields, prevent damage from insects and pests and reduce farming's impact on the environment. And more than 50 biorefineries are being built across North America to test and refine technologies to produce biofuels and chemicals from renewable biomass, which can help reduce greenhouse gas emissions.

Recent advances in biotechnology are helping us prepare for and meet societys most pressing challenges. Here's how:

Biotech is helping toheal the worldby harnessing nature's own toolbox and using our own genetic makeup to heal and guide lines of research by:

Biotech uses biological processes such as fermentation and harnesses biocatalysts such as enzymes, yeast, and other microbes to become microscopic manufacturing plants. Biotech is helping tofuel the worldby:

Biotech improves crop insect resistance, enhances crop herbicide tolerance and facilitates the use of more environmentally sustainable farming practices. Biotech is helping tofeed the worldby:

Source: Healing, Fueling, Feeding: How Biotechnology is Enriching Your Life

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Mesquite Texas Stem Cell Research | Mesquite TX Stem Cell …

Posted: July 2, 2015 at 12:56 am

Mesquite TX Stem Cell Research is a complex and beneficial science using stem cells in a lab environment to better understand how normal human development works, and also to look for and develop new treatments for a wide range of human ailments. Mesquite Texas Stem Cell Research involves two types of stem cells, classified as either embryonic stem cells or adult stem cells, which are used according to the type of Mesquite TX Stem Cell Research that is desired.

Embryonic stem cells are derived from pre-embryos, called blstocysts, approximately three to five days old. They are created specifically for fertilization treatments in the Mesquite Texas Stem Cell Research lab, will not be used to start a pregnancy, and will be discarded if not used for research. Doctors use in-vitro fertilization to create an embryo in a culture dish, which after three to five days becomes a blstocysts. Mesquite TX Stem Cell Research lab technicians then extract the inner cell mass from the blstocysts, which is used to derive embryonic stem cells in the Mesquite Texas Stem Cell Research facility.Embryonic stem cells are classified as pluripotent.

This means they can develop into any type of cell in a fully developed human body. It should be noted that embryonic stem cells cant develop into placenta or umbilical cord tissues, but they do appear to be able to develop into any other type of cell in a human body. What is so important about embryonic Mesquite TX Stem Cell Research is that it enables very flexible research, as the stem cells can be grown into any type of cell needing to be researched, at any time, at the Mesquite Texas Stem Cell Research facility. This makes for more efficient and more productive stem call research, promising a faster path to cures for ailments that devastate humanity. Mesquite TX Stem Cell Research cannot use adult stem cells to generate just any desired tissues since they are already programmed. They are quite useful nonetheless, and Mesquite Texas Stem Cell Research doctors have identified caches of adult stem cells in several tissues of the human body.

Mesquite TX Stem Cell Research in general has been able to make some wonderful advancement and create excellent treatments using adult stem cells. But there are limitations to doing Mesquite Texas Stem Cell Research using "only" adult stem cells. Adult stem cells are able to give rise to related kinds of cells in their home tissues, but for example Kidney stem cells cannot generate heart cells, and liver stem cells cannot generate brain cells.

A great deal of Mesquite TX Stem Cell Research remains to be done, and at this point Mesquite Texas Stem Cell Research doctors have developed a technique for getting an adult stem cell to behave similar to an embryonic stem cell. This specialized Mesquite TX Stem Cell Research technique creates what are called induced pluripotent stem cells (iPS). They can be produced from adult cells in skin, fatty tissue, and other sources. With this, Mesquite Texas Stem Cell Research remains a promising field. There is of course a great deal more work to do, but Mesquite TX Stem Cell Research promises to benefit mankind in many profound ways.

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Novel Stem Cells and Vesicles … – Rhode Island Hospital

Posted: July 2, 2015 at 12:56 am

Scheduled Speakers View a list of scheduled presentation titles Jason Aliotta, MD Rhode Island Hospital and Brown University Graca Almeida-Porada, MD, PhD Wake Forest/Institute for Regenerative Medicine Piero Anversa, MDBrigham & Womens Hospital/Harvard Deepa Bhartiya, PhDNational Institute for Research in Reproductive Health (NIRRH), Mumbai Giovanni Camussi, MDUniversity of Turino, Italy Barb Cohen, PhD Arex Life Sciences Laura Goldberg, MD, PhD Rhode Island Hospital and Brown University Kim Jensen Cambridge Stem Cell Institute Diane Krause, MD, PhD Yale Stem Cell Center Magdalena Kucia, PhD University of Louisville Aurelio Lorico, MD, PhD Roseman University of Health Sciences Graham C. Parker, PhD Childrens Hospital of Michigan Sharon R. Pine, PhD Rutgers Cancer Institute of New Jersey Peter J. Quesenberry, MD Rhode Island Hospital and Brown University Janina Ratajczak, MD, PhD University of Louisville Mariusz Z. Ratajczak, MD, PhD, ScD University of Louisville John Reagan, MD Rhode Island Hospital and Brown University Camillo Ricordi, MD University of Miami/Diabetes Research Institute and Cell Transplant Center James L. Sherley, MD, PhD The Adult Stem Cell Technology Center Dong-Myung Shin, PhD University of Ulsan, Korea Rouzbeh Taghizadeh, PhD Auxocell Laboratories Russell Taichman, DMD, DMSc Periodontics and Oral Medicine/University of Michigan Ciro Tetta, MD University of Turino, Italy/Translational Center for Regenerative Medicine/Fresenius Medical Care William Thilly, ScD Massachusetts Institute of Technology/ Genetics, Toxicology and Biological Engineering Daniel Weiss, MD University of Vermont Wieslaw Wiktor-Jedrzejczak University of Warsaw Downloads General Information (PDF) Abstract Guidelines (PDF) Abstract Submission Form (PDF) Daily Program and Schedule (PDF)

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Knee Stem Cell Therapy and Platelet Procedures Pittsburgh …

Posted: July 2, 2015 at 12:56 am

Rehabilitation and Pain Specialists is the only medical center in Pennsylvania to offer the nations most advanced, non-surgical stem cell and platelet treatments for knee conditions, including injuries to the knee meniscus, anterior cruciate ligament, MCL, knee cartilage and degenerative arthritis. Traditional solutions to these problems include invasive procedures, from arthroscopic knee surgery to total knee joint replacement. With this range of surgeries, patients typically require months of rehabilitation to regain strength, range-of-motion and balance, plus the patient must be prepared to take on the risks associated with surgical trauma and potential for infection. Stem Cell Therapy and Platelet treatments are minimally-invasive regenerative treatments that may help resolve knee pain with a same-day injection procedure. Patients avoid the lengthy periods of downtime and painful rehabilitation that typically follow invasive surgeries.

Stem Cells are in all of us and they are responsible for healing injured bone, ligaments, tendons and tissues. As we get older or injured, we sometimes cannot get enough of these cells into the area in need. The Regenexx Procedures help solve that problem by precisely delivering a high concentration of stem cells into the injured area and aiding your bodys ability to heal naturally. Patients experience very little down time and they typically avoid the long, painful rehabilitation periods that often follow surgery to restore joint strength and mobility. To determine if youre a candidate for these procedures, please complete our Candidate Form below.

Regenexx Procedures were recently featured on The Doctors TV show. The episode featured Dr. Christopher J. Centeno and Dr. Ron Hanson from the Centeno-Schultz Clinic in Colorado, along with a patient who sought stem cell treatment following traditional knee surgery. The 6 minute video provides a nice overview of the Stem Cell procedures that are performed at our offices in Pittsburgh, PA.

Seattle King TV recently featured Regenexx patient Paul Lyon in this news segment. Lyon chose to undergo a Regenexx-SD knee procedure, rather than an invasive and traumatic knee joint replacement surgery.

The Regenexx procedure begins when the doctor numbs the back of the hip (PSIS) and takes a small bone marrow sample through a needle, as well as a blood draw from a vein in the arm. The marrow is rich in Mesenchymal Stem Cells, which are responsible for healing damaged tissues. The stems cells are isolated from the marrow sample and platelets are isolated from the blood. After preparation, these two components will be reinjected directly into the damaged joint using advanced imaging guidance, ensuring the cells are placed in the exact location of need.

If you are suffering from a joint injury, joint pain, a non-healing fracture or a degenerative condition like osteoarthritis, you may be a good candidate for these ground-breaking stem cell and blood platelet treatments. Please complete the Procedure Candidate Form below and we will immediately email you more information.

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Alex Potoczak of Ohio Praises Umbilical Stem Cell Research …

Posted: July 2, 2015 at 12:55 am

By working in the industry as a research and laboratory assistant, Alex Potoczak of Ohio talks about umbilical stem cell research, cord blood and it's benefits.

Alex was credited with some publications including an abstract submitted to the American Society of Hematology based on his research into cancerous T-All cell lines. Alex Potoczak Ohio has a deep rooted interest in stem cell research and has devoted much of his collegiate and post-grad career to researching cures and cord blood. He worked closely with laboratories and medical records systems at North Coast Obstetrics and Gynecology. Cord blood is a sample of blood taken from a newborn baby's umbilical cord. It is a rich source of stem cells, which are hematopoietic, meaning they are precursors to blood cells. Stem Cell Research has been used to treat certain diseases of the blood and immune system. Diseases of red blood cells are inherited diseases, the immune system, and certain metabolic abnormalities. Patients with lymphoma, myelodysplasia, and severe aplastic anemia have also been successfully transplanted with cord blood. The way Cord blood is collected is by removing it from the umbilical cord vein attached to the placenta after the umbilical cord has been detached from the newborn. Cord blood and its stem cells use its hematopoietic qualities to help with genetic disorders. One unit of cord blood lacks stem cells in a quantity sufficient to treat an adult patient. The placenta is a much better source of stem cells since it contains up to ten times more than cord blood. Alex Potoczak of Ohio is an experienced graduate level laboratory researcher with an emphasis on umbilical cord stem cell research. He has worked at Case Western University and University Hospitals of Cleveland under the supervision of Dr. Mary Laughlin and Dr. Nick Greco. Also, Alex played baseball at Hamilton College where he is majoring in Economics and minored in Biology. He scored a 790 on his SAT II scores in Biology and Math, which highlights his high intelligence and creative thinking. He also received PSAT National Merit accolades as a semifinalist. Alex has unique hobbies and interests, such as Oceanography and how it relates to alternative energy. In his free time Alex organized and coordinates fundraisers at Hamilton College for the Jimmy V Foundation, Medical Ministry International, College Relay for Life and local student government. He is also very passionate about the legal system, technology, sports, philanthropy, and politics. He is a member of Hamilton College's Colleges Against Cancer, Hamilton College Republicans and Hamilton College chapter of Delta Chi Fraternity. For more details visit at: - https://alexpotoczakohio.wordpress.com/

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Cary North Carolina Stem Cell Research | Cary NC Stem Cell …

Posted: July 2, 2015 at 12:55 am

Cary NC Stem Cell Research is a complex and beneficial science using stem cells in a lab environment to better understand how normal human development works, and also to look for and develop new treatments for a wide range of human ailments. Cary North Carolina Stem Cell Research involves two types of stem cells, classified as either embryonic stem cells or adult stem cells, which are used according to the type of Cary NC Stem Cell Research that is desired.

Embryonic stem cells are derived from pre-embryos, called blstocysts, approximately three to five days old. They are created specifically for fertilization treatments in the Cary North Carolina Stem Cell Research lab, will not be used to start a pregnancy, and will be discarded if not used for research. Doctors use in-vitro fertilization to create an embryo in a culture dish, which after three to five days becomes a blstocysts. Cary NC Stem Cell Research lab technicians then extract the inner cell mass from the blstocysts, which is used to derive embryonic stem cells in the Cary North Carolina Stem Cell Research facility.Embryonic stem cells are classified as pluripotent.

This means they can develop into any type of cell in a fully developed human body. It should be noted that embryonic stem cells cant develop into placenta or umbilical cord tissues, but they do appear to be able to develop into any other type of cell in a human body. What is so important about embryonic Cary NC Stem Cell Research is that it enables very flexible research, as the stem cells can be grown into any type of cell needing to be researched, at any time, at the Cary North Carolina Stem Cell Research facility. This makes for more efficient and more productive stem call research, promising a faster path to cures for ailments that devastate humanity. Cary NC Stem Cell Research cannot use adult stem cells to generate just any desired tissues since they are already programmed. They are quite useful nonetheless, and Cary North Carolina Stem Cell Research doctors have identified caches of adult stem cells in several tissues of the human body.

Cary NC Stem Cell Research in general has been able to make some wonderful advancement and create excellent treatments using adult stem cells. But there are limitations to doing Cary North Carolina Stem Cell Research using "only" adult stem cells. Adult stem cells are able to give rise to related kinds of cells in their home tissues, but for example Kidney stem cells cannot generate heart cells, and liver stem cells cannot generate brain cells.

A great deal of Cary NC Stem Cell Research remains to be done, and at this point Cary North Carolina Stem Cell Research doctors have developed a technique for getting an adult stem cell to behave similar to an embryonic stem cell. This specialized Cary NC Stem Cell Research technique creates what are called induced pluripotent stem cells (iPS). They can be produced from adult cells in skin, fatty tissue, and other sources. With this, Cary North Carolina Stem Cell Research remains a promising field. There is of course a great deal more work to do, but Cary NC Stem Cell Research promises to benefit mankind in many profound ways.

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New York Stem Cell Treatment Center

Posted: July 2, 2015 at 12:55 am

When you sneeze, you leak urine. When you exercise, you leak urine. Man or woman, urinary incontinence is not something people discuss openly. Can we talk about it?

You wont read that many daily headlines about urologic disorders, certainly not when compared to issues like weight loss or heart disease, for example. Yet disorders of the urinary system are complicatedand common.

Are You Bothered by Bladder Pain or Leakage?

Its a fact. Millions of American women and men suffer from some form of urinary incontinence (UI). Women experience urine leakage more frequently, and there are a lot of reasons both genders lose bladder control now and then.

Urine leakage starts with the muscles and nerves that control the bladder. Located in the lower abdomen between the pelvic bones, the bladder is a muscular organ, roughly triangular in size, which expands and contracts to hold and release urine.

With a capacity to stretch from two to six inches in size, the bladder can hold between 16 and 24 ounces of fluid, about the size of a large soft drink. At a quarter full, messages are sent through the nervous system to signal you of the need to urinate and empty the bladder.

Within the bladder, a sphincter acts as a door to keep urine from leaking. When bladder muscles contract, they push out fluid as the sphincter relaxes to allow urine to pass. When bladder muscles contract prematurely, or the sphincter relaxes too oftenurine leakage can occur.

There Are Many Triggers of Urinary Incontinence

The bad news is that there many triggers for urinary leakage. The good news, is that many of these triggers are diet-related. This means if you avoid certain foods, you have a better chance of avoiding urine leakage.

Working to stimulate or irritate your bladder, steer clear of food and drinks with:

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Albuquerque NM Resources – Stem Cells: Get Facts on …

Posted: July 2, 2015 at 12:55 am

Albuquerque, New Mexico

Albuquerque is the largest city in the state of New Mexico, United States. It is the county seat of Bernalillo County and is situated in the central part of the state, straddling the Rio Grande. Albuquerque is home to the University of New Mexico (UNM), Kirtland Air Force Base, Sandia National Laboratories, Lovelace Respiratory Research Institute, and Petroglyph National Monument. The Sandia Mountains run along the eastern side of Albuquerque, and the Rio Grande flows through the city, north to south. (Source: http://en.wikipedia.org/wiki/Albuquerque)

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