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Monthly Archives: September 2014
ISU Bioethics Outreach–Stem Cells – Iowa State University
Posted: September 13, 2014 at 12:49 pm
Bioethics@
Compiled by Kristen Hessler
khessler@iastate.edu For the Biotechnology Outreach Education Center Iowa State University
In this activity, you will break into groups to review various ethical positions on stem cell research. All groups will read the introductory material from the University of Wisconsin at Madison. Then each group (NIH, CAMR, President Bush, Do No Harm) will read its own groups statement on stem cell research and fill out the questionnaire (PDF file). We will then convene to discuss each groups ethical views on stem cell research and their arguments for their views. Each group will be asked to select a representative to present their groups views and arguments.
After completing this activity, participants will be able to:
a. Identify common positions in the debate about the ethics of stem cell research; b. Analyze ethical arguments; c. Formulate, defend, and discuss productively with others their own views about the ethics of stem cell research.
Introduction: "Embryonic Stem Cells: Research at the University of Wisconsin-Madison"
National Institutes of Health (NIH): "Stem Cell Basics"
Coalition for the Advancement of Medical Research (CAMR): "Fast Action!"
The White House: President George W. Bush: Remarks by the President on Stem Cell Research
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ISU Bioethics Outreach--Stem Cells - Iowa State University
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Protein appears to protect against bone loss in arthritis
Posted: September 13, 2014 at 12:48 pm
A small protein named GILZ appears to protect against the bone loss that often accompanies arthritis and its treatment, researchers report.
Arthritis as well as aging prompt the body to make more fat than bone, and the researchers have previously shown GILZ can restore a more youthful, healthy mix. It also tamps down inflammation, a major factor in arthritis.
Now they have early evidence that GILZ might one day be a better treatment option for arthritis patients than widely used synthetic glucocorticoids, which actually increase bone loss, said Dr. Xingming Shi, bone biologist at the Medical College of Georgia at Georgia Regents University.
Their research is being presented at The American Society for Bone and Mineral Research 2014 Annual Meeting Sept. 12-15 in Houston.
In addition to bone loss, glucocorticoids, such as prednisone, produce other side effects, including diabetes. While GILZ is induced by glucocorticoids, directly overexpressing the protein appears to better target sources of bone loss and inflammation and avoid these serious side effects. .
For this study, the focus was tumor necrosis factor alpha, a proinflammatory cytokine that helps regulate immune cells and is a major player in arthritis. Tumor necrosis factor alpha primarily works though promoting inflammation, which is great if the target is cancer. However, when tumor necrosis factor alpha becomes dysregulated, it can also cause diseases like arthritis and inflammatory bowel disease.
To look specifically at the impact on bone loss, the researchers crossed mice bred to overexpress tumor necrosis factor alpha throughout the body with mice that overexpressed GILZ in just their mesenchymal stem cells. These stem cells produce the osteoblasts, which make bone. They also make fat, and when the cells stop making as much bone, they tend to make more of it. Shi's lab has shown that GILZ can coax mesenchymal stem cells back to making more bone and less fat.
While the mice that overexpressed only tumor necrosis factor alpha quickly developed arthritis along with significant bone and weight loss, those that also overexpressed GILZ had significantly less bone loss, Shi said.
"Our previous studies have shown that the GILZ transgenic mouse can make more bone," said Dr. Nianlan Yang, MCG postdoctoral fellow. "We wanted to see if GILZ would still have a bone protective effect in an inflammatory environment similar to arthritis."
Next steps include developing an oral medication, a peptide specifically, that increases GILZ expression rather than the genetic alterations the researchers have used in animal models, said Yang. She just completed a National Arthritis Foundation fellowship, which helped support that effort. They also want to see if GILZ can prevent arthritis from developing in the face of inflammation.
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Protein appears to protect against bone loss in arthritis
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Regenestem Stem Cell Treatments interview on Dr Farschian program – Video
Posted: September 13, 2014 at 11:47 am
Regenestem Stem Cell Treatments interview on Dr Farschian program
Descripcin.
By: Bioinsumos Regenerativos
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Regenestem Stem Cell Treatments interview on Dr Farschian program - Video
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The Agenda: Harrell suspends himself, gets suspended; Who'll replace him?; DSS said father was "overwhelmed"
Posted: September 12, 2014 at 10:53 pm
Turns out that under state law, House Speaker Bobby Harrell couldn't suspend himself unilaterally yesterday as he tried to do originally, so in a painfully awkward letter issued late yesterday, Speaker Pro Tem Jay Lucas, operating under the authority as presiding officer of the House, assumed when Harrell's indictment was filed Wednesday, suspended him officially. [P&C]
A number of his Republican colleagues, including Berkeley Rep. Jim Merrill are said to be vying to replace Harrell's position on the dais. [The State]
State Democrats are making the case that House Rep. Stephen Goldfinch should also be suspended over federal charges he's facing that a company he ran illegally sold stem cells, but House Clerk Charles Reid said that the charges don't rise to the level of necessitating a suspension. For his part, Goldfinch said the criminal charges shouldn't be relevant in his re-election bid. [South Strand News]
The city unanimously granted conceptual approval to the Digital Corridor's new Flagship 3 building to go up in NoMo near the corner of Morrison and Conroy St. [CRBJ]
The 'overwhelmed' father accused of killing his five children and then driving to Alabama to dump their bodies reportedly made a stop at an Upstate Dunkin Donuts over Labor Day weekend, parking by the dumpster at the shop to mask the reported "stench of death" that was apparent in the car. [P&C, WYFF, AP]
Congressman Trey Gowdy says the first public hearing for the special committee investigating the 2012 attacks in Benghazi will be held next week, on September 17. [G'ville News]
The P&C's Andrew Knapp has the heartbreaking account of slain Charleston County deputy Joseph Matuskovic's final hours before he died on duty in West Ashley at the hands of a drunken man who shot his military-style rifle through the door of his apartment when the deputy and his partner knocked. [P&C]
Some frustrated school administrators say the state dragged their feet as individual schools sought waivers from new federal healthy food guidelines for schools, leading to no S.C. schools getting exemptions that would include allowing familiar school fundraisers, such as doughnuts or candy sales. [WYFF]
According to a dossier posted on @CofCSports yesterday, new CofC basketball coach Earl Grant's musical tastes should line up well with Kresse and Cremins. Favorite song: Drake's "Hold On, Were Going Home."
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The Agenda: Harrell suspends himself, gets suspended; Who'll replace him?; DSS said father was "overwhelmed"
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Broach Foundation Commits $5 Million to Brain Cancer Research
Posted: September 12, 2014 at 10:52 pm
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Newswise The Broach Foundation for Brain Cancer Research has made a $5 million commitment to support glioblastoma multiforme research at The University of Texas MD Anderson Cancer Center. In recognition, the institution has named two patient pods at the Brain and Spine Center. The first one is named in memory of the late James Broach and the other is in honor of the foundation he and his wife, Jamie, established in 2011, months after he was diagnosed with the most aggressive form of brain cancer.
Theres no known cure for glioblastoma, and the low survival rate hasnt improved in years, due in part to inadequate funds for clinical research. In hopes of changing the statistics, the Broach Foundation directed its inaugural grant in 2012 toward research led by Jamess physician, Frederick Lang, M.D., professor and director of clinical research in Neurosurgery. Dr. Langs lab focuses on a viral smart bomb developed at MD Anderson by Juan Fueyo, M.D., professor in Neuro-Oncology - Research, called Delta-24-RGD, a type of cold virus thats engineered to infect and kill tumor cells. Lang pioneered the use of mesenchymal stem cells to deliver this virus and other biological therapies to brain tumors. Though James died at age 38 in 2013, the foundation continues to raise funds to support Lang and other collaborators at MD Anderson.
Philanthropy drives innovative research, which in turn drives the whole process of discovering new treatments and delivering them to the patient, said Lang. Thanks to the Broach Foundations generous support, we have promising clinical trials underway that mean hope for patients and their friends and loved ones coping with the effects of this deadly disease.
Fighting cancer with laughter Laughter and a positive outlook have been powerful weapons for the Broach family in their fight against a disease that is in no way funny. The couple chose to fight cancer with a combination of hard work and humor. They planned a comedy theme for their first gala fundraiser in May 2012 and called it Stand-Up for Brain Cancer. Actor, comedian and former Saturday Night Live cast member Kevin Nealon entertained a sold-out crowd at the River Oaks Country Club. Comedian Dennis Miller headlined the sold-out May 2013 event, followed by fellow Saturday Night Live alum Dana Carvey last April. Through gala proceeds, the Broach Foundation has contributed $1.7 million toward its $5 million commitment.
Were grateful to everyone who has contributed so generously to our foundation. The more we spread the news about the cutting-edge research taking place at MD Anderson and how brain cancer research continues to be underfunded, the more excited people become about wanting to join the cause, said Jamie.
NOTE TO MEDIA: Foundation representatives will view recognition plaques and attend a reception, 5-7 p.m. Sept. 15, 1515 Holcombe Blvd, R11 (access via elevator B), Rooms 2-3. Parking for media in Texas Medical Center Garage 10 will be validated.
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Broach Foundation Commits $5 Million to Brain Cancer Research
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Capitol Pain Institute Celebrating Three Employee Anniversaries and the Addition of Ten Medical Assistants
Posted: September 12, 2014 at 10:49 pm
Austin, TX (PRWEB) September 12, 2014
Representatives with Capitol Pain Institute announced today that Dr. Raimy Amasha and Dr. Anjuli Desai have completed their first year at Capitol Pain Institute while Jasmine Nelson, FNP has reached three years of service.
Dr. Matthew Schocket, founder of Capitol Pain Institute, went on to note that the medical institute also has 10 medical students or doctors who started their careers as medical assistants at Capitol Pain Institute.
Dr. Amasha is a Board Certified Anesthesiologist who completed his Anesthesiology residency at the University of Michigan and his Pain Management fellowship at The Johns Hopkins Hospital in Maryland.
His academic background is hallmarked by undergraduate training at Duke University in North Carolina, medical training at Vanderbilt University in Tennessee, and a focused research year studying stem cell biology at Stanford University in California.
As for Dr. Anjuli Desai: She is board certified in Physical Medicine & Rehabilitation and completed her fellowship training in Interventional Pain Medicine.
Areas of expertise include the treatment of back and neck pain, headaches, musculoskeletal and joint disorders, neuromodulation, including spinal cord stimulation, and acute pain management. She also performs a variety of outpatient pain management procedures including fluoroscopic-guided spine injections, nerve blocks and spinal cord stimulator trials.
The anniversaries and additions of 10 medical assistants are significant, according to Dr. Schocket, due to the fact that his staff was the first to bring stem cells therapy to Austin to relieve chronic pain.
Dr. Schocket, according to company representatives, is a recognized world-leader in the field of Pain Management.
He has lectured at multiple national and international conferences, including the American Society of Interventional Pain Physicians, the American Academy of Pain Management, the International Spine Injection Society, the Israeli Pain Society, and the International Neuromodulation Society.
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Knee arthritis one year after bone marrow stem cells by Harry Adelson, N.D. – Video
Posted: September 12, 2014 at 6:43 pm
Knee arthritis one year after bone marrow stem cells by Harry Adelson, N.D.
Christine discusses her results of her stem cell injection by Dr Harry Adelson for her arthritic knees http://www.docereclinics.com.
By: Harry Adelson, N.D.
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Knee arthritis one year after bone marrow stem cells by Harry Adelson, N.D. - Video
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Adult Stem Cell Research | Ray Flynn – Video
Posted: September 12, 2014 at 6:43 pm
Adult Stem Cell Research | Ray Flynn
Former Boston mayor Ray Flynn speaks about Catholic teaching on Adult Stem Cell Research, and his own advocacy on the issue.
By: The CatholicTV Network
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Adult Stem Cell Research | Ray Flynn - Video
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Stem cell therapy | Stem cell treatment and medicine …
Posted: September 12, 2014 at 7:44 am
Prof. Alexander Smikodub
MD Ph.D
Alexander Smikodub jr.
MD Ph.D
Our clinic offers the advanced and patented methods of fetal stem cell treatment for various conditions and diseases. This method of treatment can be found in wikipedia: Stem cell therapy. Fetal stem cells are non-specialized cells that differentiate (turn) into any other cell type of the body that form organs and tissues. Fetal stem cells that we use for treatment have huge potential for growth, differentiation and are not rejected by the patients body, which allows to achieve unique long-term clinical effects.
We have more than 15 years of experience in stem cell therapy and are the leaders of the industry. Most of the methodic used in the clinic are unique and patent protected in many countries including USA. Since 1994 prof. Alexander Smikodub Sr. was the main researcher, doctor and administrator of the clinic. Now his son, Alexander Smikodub Jr. M.D. continues his fathers venture. During these years more than 6500 patients from all over the world received fetal stem cell treatment, resulting in significant improvement of their conditions, and in case of timely contact with us in complete cure of the diseases still considered lethal by most medical institutions.
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Stem cells are the new word in the medical science, possibly the new revolution. Their importance can be compared with antibiotics discovery or the first successful heart transplantation. They are the inner restorative and regenerative reserve of your body, found in blood, fat layer and bone marrow. After injection of a big stem cells doze, impaired tissues are recovered, regeneration speed is increased and overall condition is greatly improved. We use only material from healthy patients, which passes multiple security checks. They are a perfect material for treating a wide variety of neural and physical diseases.
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Stem cell therapy | Stem cell treatment and medicine ...
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Dr. Jeff Christiansen is Now Offering Stem Cell Therapy for Pets at Five Brevard County Animal Hospitals and Beyond
Posted: September 12, 2014 at 7:44 am
Melbourne, Florida (PRWEB) September 11, 2014
Central Florida board-certified veterinary surgeon, Jeffrey S. Christiansen is proud to announce his partnerships with several Brevard County animal hospitals to bring regenerative veterinary medicine to pets. Dr. Christiansen has been working in the area since January 2006, credentialed to do stem cell therapy on small animals since 2008, and is happy to now offer his expertise through five different locations.
Over the years Dr. Christiansen has used stem cell therapy with Vet-Stem, Inc. on cruciate ligament and meniscus injuries, as well as osteoarthritis of the hips and other joints. Once Dr. Christiansen has identified a patient as a good stem cell therapy candidate, the pet undergoes a simple surgery to collect fat that is sent overnight to Vet-Stems lab in California. The day after the collection the fat is processed so stem cells can be extracted and put into concentrated, injectable doses. These doses are shipped back overnight to Dr. Christiansen and he is able to place them in the affected areas of the patient to encourage healing and regeneration.
Even if a pet is not an immediate candidate for stem cell therapy, but is undergoing an orthopedic or other type of surgery with Dr. Christiansen, he offers the ability to collect a small sample of fat for future stem cell use with Vet-Stem. Vet-Stem has the ability to cryo-bank stem cells and grow them in the future to provide doses when needed. This service is called StemInsure for dogs, and provides the insurance of a pet having a lifetime of stem cell therapy available from a single sample collection.
Stem cell therapy can be an alternative for pets that are unable to take anti-inflammatories or have digestive issues, as well as pets that are looking at long-term pain management. Because the stem cells come directly from the patient risk is low, and the procedure is natural.
As part of Superior Veterinary Surgical (and less-invasive) Solutions, Dr. Christiansen will be offering stem cell therapy at the following clinics beginning in September: Island Animal Hospital in Merritt Island, Brevard Animal Emergency Hospital in Malabar, Aloha Pet and Bird Hospital in Indian Harbour, Maybeck Animal Hospital in West Melbourne, and the Animal Emergency and Referral Center in Fort Pierce. He is bringing nearly 20 years of veterinary medicine experience with him, and takes pride in specializing in soft tissue, orthopedic, and spinal surgery.
About Dr. Christiansen and Superior Veterinary Surgical Solutions Jeffrey S. Christiansen, DVM, DACVS graduated from the University of Tennessee College of Veterinary Medicine in 1996. He completed his surgical residency in 2001, following an internship, and in 2002 he became a Diplomate of the American College of Veterinary Surgeons. Dr. Christiansen has been practicing in Brevard County since the beginning of 2006 and runs Superior Veterinary Surgical Solutions. In addition to stem cell therapy, some special areas of interest to Dr. Christiansen include artificial urethral sphincter (for incontinence), juvenile pubic symphysiodesis (for prevention of arthritis secondary to hip dysplasia), prophylactic gastropexy (for prevention of gastric dilatation-volvulus, commonly referred to as bloat), subcutaneous ureteral bypass (for obstructions between the kidney and bladder in cats), ureteral stenting (for obstruction between the kidney and bladder in dogs), and urethral stenting (for urethral obstruction), tibial tuberosity advancement (for tears of the cranial cruciate ligament; ACL in people) and tracheal stenting (for tracheal collapse).
About Vet-Stem, Inc. Since its formation in 2002, Vet-Stem, Inc. has endeavored to improve the lives of animals through regenerative medicine. As the first company in the United States to provide an adipose-derived stem cell service to veterinarians for their patients, Vet-Stem pioneered the use of regenerative stem cells for horses, dogs, cats, and some exotics. In 2004 the first horse was treated with Vet-Stem Regenerative Cell Therapy for a tendon injury that would normally have been career ending. Ten years later Vet-Stem celebrated its 10,000th animal treated, and the success of establishing stem cell therapy as a regenerative medicine for certain inflammatory, degenerative, and arthritic diseases. As animal advocates, veterinarians, veterinary technicians, and cell biologists, the team at Vet-Stem tasks themselves with the responsibility of discovering, refining, and bringing to market innovative medical therapies that utilize the bodys own healing and regenerative cells. For more information about Vet-Stem and Regenerative Veterinary Medicine visit http://www.vet-stem.com or call 858-748-2004.
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Dr. Jeff Christiansen is Now Offering Stem Cell Therapy for Pets at Five Brevard County Animal Hospitals and Beyond
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