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Monthly Archives: October 2010
Bacteria May Predict Chances of Colon Cancer
Posted: October 11, 2010 at 12:12 pm
(HealthDay News) -- Researchers report that germs living in your gut could affect your risk of developing colon cancer.
The findings suggest that signs of the existence of some germs "are more frequently detected in subjects with polyps, early lesions that can develop into cancer, while other bacterial signatures are less frequently observed in such individuals," Tyler Culpepper, a University of Florida researcher, said in a news release.
Culpepper and colleagues studied 91 patients and took biopsy samples from their colons. They analyzed the bacteria in 30 people who had at least one polyp and 30 people who didn't but were of similar age and gender.
Researchers found some bacterial signatures only in those who had polyps and others only in those who didn't. Others were more common in one group or the other.
The findings suggest that future screening tests could aim to detect signs of trouble in the colon by measuring bacteria levels, Culpepper said. Read more...
Posted in Integrative Medicine
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Colloidal silver to boost immunity and overall health
Posted: October 11, 2010 at 12:11 pm
This article has some useful information but, of course, cannot openly tell their readers that this is truly valuable so they have to attack it somehow. If you are not taking ACS 200 yourself, maybe you do not believe that it has germ killing powers?
I believe that infections are part of our current health crisis! I believe that it is well proven that we have organisms in the mouth that are difficult to identify and dangerous when they make their way into the systemic circulation, which they ALWAYS manage to do. I hold my ACS 200 in the mouth at least a minute 2-3 times a day. I think that lowering my total body burden of infections is just as useful for optimizing my health as lowering my burden of other toxins, like heavy metals.
Your patients may be confused by this article so take a moment to see it lacks clarity and even contradicts itself. Read more...
Posted in Integrative Medicine
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Positive Brain Changes Seen After Body-Mind Meditation
Posted: October 11, 2010 at 12:11 pm
(HealthDay News) -- Positive brain changes take hold after just 11 hours of practicing a form of meditation, the results of a new study suggest.
The study included 45 University of Oregon students who were randomly selected to be in either a study group that did integrative body-mind training (IBMT) or a control group that did relaxation training. IBMT was adapted from traditional Chinese medicine in the 1990s.
A comparison of scans taken of the students' brains before and after the training showed that those in the IBMT group had increased brain connectivity. The changes were strongest in connections involving the anterior cingulate, an area that plays a role in the regulation of emotions and behavior, Yi-Yuan Tang of Dalian University of Technology in China, University of Oregon psychologist Michael I. Posner, and colleagues found.
The boost in brain connectivity began after six hours of IBMT and became more apparent after 11 hours of practice, according to the report published in the Aug. 16-21 online edition of the Proceedings of the National Academy of Sciences. Read more...
Memory concentration, loss of memory
Posted in Integrative Medicine
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Eating meat may cause severe allergic reactions in some people
Posted: October 11, 2010 at 12:11 pm
Meat allergies may be much more common than previously thought and may even induce potentially fatal anaphylaxis in some people, according to a study conducted by researchers from the University of Virginia and presented at the annual meeting of the American Academy of Allergy, Asthma and Immunology in New Orleans.
The researchers tested three groups of people across the U.S. Southeast with a history of recurrent anaphylaxis without known cause for an immune reaction to alpha-gal, a kind of sugar found in mammal meat.
Although most allergic reactions are caused by proteins, scientists recently discovered that alpha-gal is responsible for anaphylactic reactions to cetuximab, a cancer drug. Further studies revealed that people who experience immune responses to alpha-gal also develop allergic symptoms within three to six hours of eating mammalian meat.
Alpha-gal is not found in the flesh of bird or fish.
The researchers found that between 20 and 50 percent of participants tested positive for allergy to alpha-gal. Overall, 25 of 60 participants (42 percent) showed signs of meat allergy. Read more...
Female Sexual health
Posted in Integrative Medicine
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Careers in cell therapy & regenerative medicine
Posted: October 11, 2010 at 12:11 pm
As you will see just below, this post falls under the category of a thinly veiled and somewhat shameless plug which I hope you'll tolerate if I'm transparent about it upfront and I add what may be a little useful commentary along the way.
I won't have to convince "regular" readers of this "irregular" blog that regenerative medicine is one of the fastest growing life science sectors.
Given the pace of the industry's growth, the amount of public money being "invested" in the sector, and the general enthusiasm that the science generates, it is no surprise that is increasingly an area of interest for those seeking a new career path.
One commonly held misconception is that career opportunities in the sector are limited largely to those in early-stage research.
While it is true that the industry is still in the nascent stages of commercial development compared to other more mature segments in the broader biopharmaceutical industry, careers in regenerative medicine span the full research and commercial spectrum from pre-clinical to clinical research in both academic and corporate settings, manufacturing, regulatory, quality, operations, logistics, finance, business development, marketing, sales, communications, and executive management.
As has been discussed here in the past, most analysts agree that in 2008 the industry passed the $1 billion mark in annual revenue generated from sale of approved therapeutic products falling under the regenerative medicine category (see here for more in-depth analysis).
Furthermore, most large multinational life science companies are now investing heavily into the sector on the promise that it will revolutionize healthcare in the coming decades.
I believe the 2008 decision by Pfizer to create a substantial new Regenerative Medicine division will be seen as a seminal turning point in corporate perspectives on the industry. Since that point most life sciences have begun investing in regenerative medicine strategies and the trend has even leaked outside of life science to companies such as Google Ventures which has informally identified regenerative medicine as one of their primary areas of interest when looking at companies in which to invest.
Most major universities have now created both academic and research programs dedicated to the emerging field of regenerative medicine such that there is a new class of graduates now emerging in both scientific and commercial disciplines with regenerative medicine as a primary focus.
However, one of the difficulties with finding a career in regenerative medicine is that it is comprised of what has heretofore been fairly discrete disciplines of stem cell biology, pharmaceutical sciences, biotechnology, tissue engineering, stem cell transplantation, device technologies, cell therapies, etc.
Furthermore, most recruiters and online job sites have very little experience or focus on the industry making recruiting difficult for positions in regenerative medicine companies or departments. The task is further complicated by the fact that the candidate pool is small and diversely spread over a multitude of disciplines, centers, and a multitude of small companies.
Finally there are only now emerging industry publications, organizations, online communities, and websites that truly represent the broad spectrum of regenerative medicine and that can be used as central resources for recruiting.
All this is why my partners and I saw the need for an online recruiting tool that really focused on regenerative medicine in a way that would support the industry's maturation. What we wanted to bring was a very simple solution that would create as much value as possible for those looking to recruit the right talent into their regenerative medicine efforts. This was the genesis behind RegenerativeMedicineJobs.com.
(here comes the shameless part....)
About RMJ
At RegenerativeMedicineJobs.com, we believe the growth trajectory of this industry requires a specialized, online recruiting system – one that is more than just a website for posting jobs but also plugged into the large and diverse network of associations, publications, and social media that serves this industry.
RegenerativeMedicineJobs.com is a specialized online job board focused on recruiting for positions in the rapidly growing field of regenerative medicine. The site is simple to use and focused in scope. But this is more than just another website.
RMJ has developed a sophisticated system designed to leverage our extensive network in RM to ensure every post gets maximum attention and attracts the best candidates.
Traffic is pulled to the site and job postings are pushed to a targeted audience by focused social media and marketing campaigns. This is the latest way to recruit for any position in a regenerative medicine department, division, or company. This is regenerative medicine recruiting with a focus.
RegenerativeMedicineJobs.com (RMJ) is a collaboration between CTG Consulting, Co. and Pencilneck Software, Co. The personnel behind this collaboration created Cell Therapy News, Cell Therapy Blog, the LinkedIn Cell Therapy Industry Group, and have produced over a dozen organizational or event-based websites in the cell therapy, stem cell, and regenerative medicine space.
The site has been designed to be simple and intuitive with only one goal in mind: to be the best online tool for recruiting personnel into positions in the regenerative medicine industry.
We don't offer resume posting, career advice, assistance building your CV, hand holding, shoulders to cry on, or job postings outside of regenmed. We believe in the value of specialization.
The site is a listing of regenerative medicine jobs (period). All types of jobs for all types of organizations but only regenmed job (period).
We have only one rule: the jobs posted must be for a position within the regenerative medicine space. We define regenerative medicine as anything involving cell therapy, stem cells as therapies or tools for discovery or toxicity testing, or non-cell based programs/products (e.g., small molecules, biologics, devices, etc) used to replace or regenerate cells, tissues, or organs to restore, repair, or establish normal function.
The site has a topical niche with no regional focus or bias. This is meant to be a global tool equally useful for a company or university in Poland, Taiwan, Brazil, the United States, etc.
The site is also meant to be useful for recruiting any positions scientific or commercial, business or technical, executive or laborer.
*
We hope you find it useful.
We hope it contributes to the industry's growth and maturation.
We hope you will provide us feedback on what we're doing well and what we can do better.
Posted in Regenerative Medicine
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Parkinsonian Power Failure: Neuron Degeneration May Be Caused by a Cellular Energy System Breakdown
Posted: October 11, 2010 at 12:11 pm
In the past researchers have observed an association between poor mitochondrial function and Parkinson's disease, a neurodegenerative disorder of the central nervous system that impairs speech and motor functions and affects five million people worldwide. A new meta-analysis suggests that low expression levels of 10 related gene sets responsible for mitochondrial machinery play an important role in this disorder--all previously unlinked to Parkinson's. The study, published online today in Science Translational Medicine , further points to a master switch for these gene sets as a potential target of future therapies. [More]
Posted in Gene therapy
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Was Darwin a Punk? A Q&A with Punker-Paleontologist Greg Graffin
Posted: October 11, 2010 at 12:11 pm
Editor's Note: This is an expanded version of the Q&A that will appear in the November 2010 issue of Scientific American.
Name: Greg Graffin [More]
Greg Graffin - BadReligion - Punk rock - Punk - Shopping
Posted in Gene therapy
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Stem Cells from Reprogrammed Adult Cells Found to Bring Along Genetic Defects of Their Donors
Posted: October 11, 2010 at 12:11 pm
Realistic stem cell therapies to replace diseased or damaged tissue may still be years away, but researchers have uncovered a promising new use for these undifferentiated cells: they can be programmed to become patient-specific laboratory models of inherited liver disease. These new tools could be useful for teasing out disease mechanisms and testing new drug therapies.
Scientists from the University of Cambridge's Institute for Medical Research obtained skin cells from 10 patients--seven who had various forms of inherited liver disease, and three healthy controls. They reprogrammed the skin cells, rejuvenating them into an embryolike state (using the four-gene approach described in 2007). The researchers then cultured these so-called induced pluripotent stem cells (iPS cells) in a mixture of chemical factors that triggered their conversion into liver cells, which had the appearance and functional properties of native liver cells.
Stem cell - Cambridge University - Liver - Medical Research - Disease
Posted in Gene therapy
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Oracle starts the Oracle Health Sciences Institute (OHSI), in partnership with Sun Labs
Posted: October 11, 2010 at 12:11 pm
The Institute is focused on research that will accelerate IT innovation to advance personalized medicine and the delivery of safe and effective treatments and health care services to patients around the globe. OHSI will work in tandem with academic research centers, focusing on a targeted set of research areas fundamental to the R&D and health care delivery challenges facing health sciences organizations today. Research priorities currently include: artificial intelligence and semantic technology; genomic, genetic and phenotypic data analysis; data mining to support optimization of clinical trials; and predictive algorithms and other technology to advance patient safety and provide advanced decision support at the point of care.Academic institutions interested in collaborating with OHSI in these focus areas should contact OHSI representatives at Oracle http://linkd.in/bXf98c
Oracle starts Oracle Health Sciences Institute (OHSI), in partnership with Sun Labs. This is exiting news and I hope we get to see the participation of Open Source Drug Development Network (OSDD) and initiative by CSIR India earlier supported by Sun Microsystems
Posted in Genetic medicine
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The SaaS impact on solution selling for ISVs (via Inner Lining)
Posted: October 11, 2010 at 12:11 pm
Product marketing teams look at the software buying cycle as a consistent series of steps: awareness, consideration, trial, purchase, implementation and renewal. For years, these steps have been manipulated through solution selling where the key to success is control. By knowing the buyer, the steps and the product, a skilled selling team is able to control the process and predict favorable outcomes on a consistent basis. Oracle, SAP and Mic … Read More
via Inner Lining
Posted in Genetic medicine
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