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Category Archives: Stem Cell Research

Drivers of Healthy Gut Maintenance Uncovered – Technology Networks

Posted: June 17, 2020 at 9:45 am

Researchers at the Francis Crick Institute have found two genes that regulate the differentiation of stem cells in the small intestine, offering valuable insight into how the body develops and maintains a healthy gut.

Cells in the lining of the small intestine are replaced around every five days, the quickest rate for any organ in the body. This fast replacement helps the lining cope with the damage it suffers as a result of breaking down food and absorbing nutrients.

This process, which is important for the healthy functioning of the small intestine, is supported by the stem cells in a part of the small intestine called the crypt.

In their study, published in Gastroenterology, the researchers found two genes, MTG8 and MTG16, which are highly expressed in cells that have just left the stem cell zone. These genes 'switch off' signals that keep these cells in a multipotent or 'immature' state, leading them to start to differentiate.

When the team analysed intestinal tissue and small intestine organoids grown from mice lacking these genes, they found there were many more stem cells, indicating that the process of differentiation was impeded.

Anna Baulies, lead author and postdoctoral training fellow in the Stem Cell and Cancer Biology lab at the Crick says: "These genes maintain the flow of cells which are needed for the healthy functioning of the small intestine, starting the stem cells on the road to become enterocyte cells which are needed to absorb nutrients."

Importantly, by working with human small intestine organoids, the researchers also found that while the stem cells are still in the crypt, these genes are repressed by a key developmental pathway, Notch signalling. This ensures the stem cells do not differentiate too early.

Vivian Li, senior author and group leader of the Stem Cell and Cancer Biology lab at the Crick says, "Understanding the role these genes play in healthy tissue will also help us to understand how the intestine regularly regenerates and also if these genes are a helpful or harmful force in the presence of disease."

"For example, loss of these genes may increase the number of stem cells and contribute to colorectal cancer progression. Further study on the underlying mechanism might be helpful to limit the number of stem cells in the cancer."

The signal that these genes repress, Wnt signalling, also keeps stem cells in a multipotent state in many other tissues, including the skin, stomach, liver and brain. These findings could therefore help other research into stem cell differentiation outside of the small intestine.

The researchers will continue this work, looking to understand more about the mechanism these two genes use to regulate stem cell differentiation and regeneration.

Reference:Baulies, A., Angelis, N., Foglizzo, V., Danielsen, E. T., Patel, H., Novellasdemunt, L., . . . Li, V. S. (2020). The Transcription co-Repressors MTG8 and MTG16 Regulate Exit of Intestinal Stem Cells From Their Niche and Differentiation into Enterocyte vs Secretory Lineages. Gastroenterology. doi:10.1053/j.gastro.2020.06.012

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GLOBAL HUMAN EMBRYONIC STEM CELL MARKET Analysis 2020 With COVID 19 Impact Analysis| Leading Players, Industry Updates, Future Growth, Business…

Posted: June 17, 2020 at 9:45 am

With a full devotion and dedication this superior GLOBAL HUMAN EMBRYONIC STEM CELL MARKET report is presented to the clients that extend their reach to success. Market parameters covered in this advertising report can be listed as market definition, currency and pricing, market segmentation, market overview, premium insights, key insights and company profile of the key market players. Each parameter included in this GLOBAL HUMAN EMBRYONIC STEM CELL MARKET business research report is again explored deeply for the better and actionable market insights. Geographical scope of the products is also carried out comprehensively for the major global areas which helps define strategies for the product distribution in those areas.

TheGlobal Human Embryonic Stem Cell Marketstudy with 100+ market data Tables, Pie Chat, Graphs & Figures is now released by Data Bridge Market Research. The report presents a complete assessment of the Market covering future trend, current growth factors, attentive opinions, facts, and industry validated market data forecast till 2026. Delivering the key insights pertaining to this industry, the report provides an in-depth analysis of the latest trends, present and future business scenario, market size and share ofMajor Players such as Arizona Board of Regents, STEMCELL Technologies Inc, Cellular Engineering Technologies, CellGenix GmbH, PromoCell GmbH, Lonza, Kite Pharma, Takeda Pharmaceutical Company Limited, BrainStorm Cell Limited., CELGENE CORPORATION, Osiris Therapeutics,Inc, U.S. Stem Cell, Inc and amny More

Global human embryonic stem cell market estimated to register a healthy CAGR of 10.5% in the forecast period of 2019 to 2026. The imminent market report contains data for historic year 2017, the base year of calculation is 2018 and the forecast period is 2019 to 2026. The growth of the market can be attributed to the increase in tissue engineering process.

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Market Dynamics:

Set of qualitative information that includes PESTEL Analysis, PORTER Five Forces Model, Value Chain Analysis and Macro Economic factors, Regulatory Framework along with Industry Background and Overview.

Global Human Embryonic Stem Cell Market By Type (Totipotent Stem Cells, Pluripotent Stem Cells, Unipotent Stem Cells), Application (Regenerative Medicine, Stem Cell Biology Research, Tissue Engineering, Toxicology Testing), End User (Research, Clinical Trials, Others), Geography (North America, Europe, Asia-Pacific, South America, Middle East and Africa) Industry Trends and Forecast to 2026

Global Human Embryonic Stem Cell Research Methodology

Data Bridge Market Research presents a detailed picture of the market by way of study, synthesis, and summation of data from multiple sources.The data thus presented is comprehensive, reliable, and the result of extensive research, both primary and secondary. The analysts have presented the various facets of the market with a particular focus on identifying the key industry influencers.

Major Drivers and Restraints of the Human Embryonic Stem Cell Industry

Complete report is available (TOC) @https://www.databridgemarketresearch.com/toc/?dbmr=global-human-embryonic-stem-cell-market

The titled segments and sub-section of the market are illuminated below:

By Type

By Application

By End User

Top Players in the Market are:

Some of the major companies functioning in global human embryonic stem cell market are Arizona Board of Regents, STEMCELL Technologies Inc, Cellular Engineering Technologies, CellGenix GmbH, PromoCell GmbH, Lonza, Kite Pharma, Takeda Pharmaceutical Company Limited, BrainStorm Cell Limited., CELGENE CORPORATION, Osiris Therapeutics,Inc, U.S. Stem Cell, Inc, Waisman Biomanufacturing, Caladrius, Pfizer Inc., Thermo Fisher Scientific, Merck KGaA, Novo Nordisk A/S, Johnson & Johnson Services, Inc and SA Biosciences Corporation among others.

How will the report help new companies to plan their investments in the Human Embryonic Stem Cell market?

The Human Embryonic Stem Cell market research report classifies the competitive spectrum of this industry in elaborate detail. The study claims that the competitive reach spans the companies of.

The report also mentions about the details such as the overall remuneration, product sales figures, pricing trends, gross margins, etc.

Information about the sales & distribution area alongside the details of the company, such as company overview, buyer portfolio, product specifications, etc., are provided in the study.

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Some of the Major Highlights of TOC covers:

Chapter 1: Methodology & Scope

Definition and forecast parameters

Methodology and forecast parameters

Data Sources

Chapter 2: Executive Summary

Business trends

Regional trends

Product trends

End-use trends

Chapter 3: Human Embryonic Stem Cell Industry Insights

Industry segmentation

Industry landscape

Vendor matrix

Technological and innovation landscape

Chapter 4: Human Embryonic Stem Cell Market, By Region

Chapter 5: Company Profile

Business Overview

Financial Data

Product Landscape

Strategic Outlook

SWOT Analysis

Thanks for reading this article, you can also get individual chapter wise section or region wise report version like North America, Europe or Asia.

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GLOBAL HUMAN EMBRYONIC STEM CELL MARKET Analysis 2020 With COVID 19 Impact Analysis| Leading Players, Industry Updates, Future Growth, Business...

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Global Bone Marrow-Derived Stem Cells (BMSCS) Market (COVID 19 Impact Analysis) Data Highlighting Major Vendors, Promising Regions, Anticipated Growth…

Posted: June 17, 2020 at 9:45 am

Global Bone Marrow-Derived Stem Cells (BMSCS) Market research report delivers comprehensive analysis of the market structure along with estimations of the various segments and sub-segments of the market. This study also analyzes the market status, market share, growth rate, sales volume, future trends, market drivers, market restraints, revenue generation, opportunities and challenges, risks and entry barriers, sales channels, and distributors. The company profiles of all the chief and dominating market players and brands who are taking steps such as product launches, joint ventures, mergers and acquisitions are mentioned in the report. With the use of SWOT analysis and Porters Five Forces analysis which are two of the standard, prominent and full-proof methods, this Global Bone Marrow-Derived Stem Cells (BMSCS) Market report is been framed.

Global Bone Marrow-Derived Stem Cells (BMSCS) Market By Service Type (Sample Preservation and Storage, Sample Analysis, Sample Processing, Sample Collection and Transportation), Application (Personalized Banking Applications, Research Applications, Clinical Applications), Country (U.S., Canada, Mexico, Germany, Italy, U.K., France, Spain, Netherland, Belgium, Switzerland, Turkey, Russia, Rest of Europe, Japan, China, India, South Korea, Australia, Singapore, Malaysia, Thailand, Indonesia, Philippines, Rest of Asia- Pacific, Brazil, Argentina, Rest of South America, South Africa, Saudi Arabia, UAE, Egypt, Israel, Rest of Middle East & Africa), Market Trends and Forecast to 2027

By providing an absolute overview of the market, Global Bone Marrow-Derived Stem Cells (BMSCS) Market report covers various aspects of market analysis, product definition, market segmentation, key developments, and the existing vendor landscape. Such market insights can be accomplished with this comprehensive Global Bone Marrow-Derived Stem Cells (BMSCS) Market research report which takes into account all the aspects of current and future market. The report provides wide-ranging analysis of the market structure along with the estimations of the various segments and sub-segments of the market. This Global Bone Marrow-Derived Stem Cells (BMSCS) Market research report delivers an analytical measurement of the main challenges faced bythe business currently and in the upcoming years.

Bone marrow-derivedstem cells(BMSCS) marketis expected to gain market growth in the forecast period of 2020 to 2027. Data Bridge Market Research analyses the market to growing at a CAGR of 10.4% in the above-mentioned forecast period. Increasing awareness regarding the benefits associates with the preservation of bone marrow derived stem cells will boost the growth of the market.

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The major players covered in the bone marrow-derived stem cells (BMSCS) market report are CBR Systems, Inc, Cordlife Sciences India Pvt. Ltd., Cryo-Cell International, Inc.ESPERITE N.V., LifeCell International Pvt. Ltd., StemCyte India Therapeutics Pvt. Ltd, PerkinElmer Inc, Global Cord Blood Corporation., Smart Cells International Ltd., Vita 34 among other domestic and global players. Market share data is available for Global, North America, Europe, Asia-Pacific (APAC), Middle East and Africa (MEA) and South America separately. DBMR analysts understand competitive strengths and provide competitive analysis for each competitor separately.

Some of the factors such as introduction of novel technologies for the preservation of stem cells and their storage, surging investment that will help in research activities leading to stem cells benefits, adoption of hemotopoietic stem cell transplantation system will accelerate the growth of the bone marrow-derived stem cells (BMSCS) market in the forecast period of 2020-2027. Various factors that will create opportunities in the bone marrow-derived stem cells (BMSCS) market are increasing occurrences of various diseases along with rising applications in emerging economies.

Large cost of operation and strict regulatory framework will restrict the growth of bone marrow-derived stem cells (BMSCS) market in the above mentioned forecast period. Ethical concern leading to stem cells will become the biggest challenge in the market growth.

Global Bone Marrow-Derived Stem Cells (BMSCS) Market By Service Type (Sample Preservation and Storage, Sample Analysis, Sample Processing, Sample Collection and Transportation), Application (Personalized Banking Applications, Research Applications, Clinical Applications), Country (U.S., Canada, Mexico, Germany, Italy, U.K., France, Spain, Netherland, Belgium, Switzerland, Turkey, Russia, Rest of Europe, Japan, China, India, South Korea, Australia, Singapore, Malaysia, Thailand, Indonesia, Philippines, Rest of Asia- Pacific, Brazil, Argentina, Rest of South America, South Africa, Saudi Arabia, UAE, Egypt, Israel, Rest of Middle East & Africa), Market Trends and Forecast to 2027

Global Bone Marrow-Derived Stem Cells (BMSCS) Market Scope and Market Size

Bone marrow-derivedstem cells(BMSCS) market is segmented on the basis of service type and application. The growth amongst these segments will help you analyse meagre growth segments in the industries, and provide the users with valuable market overview and market insights to help them in making strategic decisions for identification of core market applications.

Thisbonemarrow-derived stem cells (BMSCS) market report provides details of new recent developments, trade regulations, import export analysis, production analysis, value chain optimization, market share, impact of domestic and localised market players, analyses opportunities in terms of emerging revenue pockets, changes in market regulations, strategic market growth analysis, market size, category market growths, application niches and dominance, product approvals, product launches, geographic expansions, technological innovations in the market. To gain more info on bone marrow-derived stem cells (BMSCS) market contactData Bridge Market Researchfor anAnalyst Brief, our team will help you take an informed market decision to achieve market growth.

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Bone Marrow-Derived Stem Cells (BMSCS) Market Country Level Analysis

Bone marrow-derivedstem cells(BMSCS) market is analysed and market size insights and trends are provided by country, service type and application as referenced above.

The country section of the bone marrow-derivedstem cells(BMSCS) market report also provides individual market impacting factors and changes in regulation in the market domestically that impacts the current and future trends of the market. Data points such as consumption volumes, production sites and volumes, import export analysis, price trend analysis, cost of raw materials, down-stream and upstream value chain analysis are some of the major pointers used to forecast the market scenario for individual countries. Also, presence and availability of global brands and their challenges faced due to large or scarce competition from local and domestic brands, impact of domestic tariffs and trade routes are considered while providing forecast analysis of the country data.

Healthcare Infrastructure Growth Installed Base and New Technology Penetration

Bone marrow-derived stem cells (BMSCS) market also provides you with detailed market analysis for every country growth in healthcare expenditure for capital equipments, installed base of different kind of products for bone marrow-derived stem cells (BMSCS) market, impact of technology using life line curves and changes in healthcare regulatory scenarios and their impact on the bone marrow-derived stem cells (BMSCS) market. The data is available for historic period 2010 to 2018.

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Key Highlights of Report

Competitive Landscape and Bone Marrow-Derived Stem Cells (BMSCS) Market Share Analysis

Bone marrow-derived stem cells (BMSCS) market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies focus related to bone marrow-derived stem cells (BMSCS) market.

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Data Bridge Market Researchset forth itself as an unconventional and neoteric Market research and consulting firm with unparalleled level of resilience and integrated approaches. We are determined to unearth the best market opportunities and foster efficient information for your business to thrive in the market. Data Bridge endeavors to provide appropriate solutions to the complex business challenges and initiates an effortless decision-making process.

Contact:

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Global Bone Marrow-Derived Stem Cells (BMSCS) Market (COVID 19 Impact Analysis) Data Highlighting Major Vendors, Promising Regions, Anticipated Growth...

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Magenta and Beam to Further Explore MGTA-117 – PharmaLive

Posted: June 17, 2020 at 9:45 am

Cambridge-based Magenta Therapeutics announced today that it has entered a non-exclusive research and clinical collaboration agreement with Beam Therapeutics. The goal is to evaluate the potential use of MGTA-117, Magentas novel targeted antibody drug conjugate (ADC) for the conditioning of patients with sickle cell disease and beta-thalassemia.

Conditioning is necessary to prepare a patients body to receive edited cells. Existing conditioning regimens rely on nonspecific chemotherapy or radiation. MGTA-117 precisely targets only hematopoietic stem and progenitor cells, sparing immune cells. It has also shown high selectivity, potent efficacy, and wide safety margins.

Beam has demonstrated the ability to edit individual DNA bases in hematopoietic stem cells with little impact on the viability of edited cells, relative to unedited cells, using its novel base editing technology. MGTA-117 and Beams base editors could advance treatment in patients with sickle cell disease or beta-thalassemia.

We believe patients will benefit from a more precise process to remove hematopoietic stem cells and prepare them to receive genetic medicines, said Jason Gardner, D.Phil., president and chief executive officer, Magenta Therapeutics. Magenta has developed targeted ADCs as the preferred modality for our conditioning programs, and we have designed MGTA-117 specifically to optimize it for use with a genetically-modified cell product delivered in a transplant setting. Beams next-generation base editing technology complements our next-generation conditioning approach very well, and we are excited to combine these strengths to address the still-significant unmet medical needs of the sickle cell and beta-thalassemia patient communities.

This is not the only collaboration agreement Magenta has entered as of late. On June 11, the company announced that it had entered a clinical collaboration agreement with the National Marrow Donor Program (NMDP)/Be The Match to evaluate the use of MGTA-145, a CXCR2 agonist.

MGTA-145 works in combination with plerixafor, a CXCR4 antagonist, to leverage the physiological mechanism of stem cell mobilization into peripheral blood. It has achieved all safety and activity endpoints to date.

Magenta is delighted to build upon its successful partnership with NMDP/Be The Match through this clinical collaboration, said John Davis Jr., M.D., M.P.H., M.S., Head of Research & Development and Chief Medical Officer, Magenta. The NMDP/Be The Match team brings unparalleled experience in stem cell transplant, operating the largest and most diverse marrow registry in the world, with a global network of 187 transplant centers. We are excited to collaborate with them to explore MGTA-145 in allogeneic transplant, which makes up nearly half of the transplants that take place each year in the U.S. and Europe. MGTA-145 mobilizes robust numbers of functional stem cells in a single day, allowing donors to potentially avoid multiple visits to infusion centers or hospitals, which has been a major concern for donors during the COVID-19 pandemic. The large number of functional cells may also result in faster recovery and improved outcomes for patients undergoing a life-saving allogeneic transplant.

Under the collaboration agreement, Magenta and NMDP/Be The Match will conduct a Phase 2 clinical trial of MGTA-145 to mobilize and collect hematopoietic stem cells from donors. These stem cells will then be given to patients with blood cancers who need a stem cell transplant. Magenta will retain all commercial rights to MGTA-145.

There is a significant need for new medicines for stem cell mobilization for patients and stem cell donors, and this need is only exacerbated during the COVID-19 pandemic as donors in particular prefer to avoid the hospital setting, said Steven Devine, M.D., Chief Medical Officer, NMDP/Be The Match. Clinical data generated with MGTA-145 to date suggest that its robust mobilization of functional stem cells in a single day could improve both the donor experience and patient outcomes. We are pleased to partner with Magenta to further transform the practice of stem cell transplant. We look forward to initiating this Phase 2 study.

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Magenta and Beam to Further Explore MGTA-117 - PharmaLive

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Six tales from the trenches of running a startup – MIT Technology Review

Posted: June 17, 2020 at 9:45 am

Our company has built a platform to produce high-quality cells and tissues for regenerative medicine. That pursuit involves multiple disciplines, which means everyone here is an expert in a different language. Some of us are fluent in stem-cell biology, others in optical engineering, others in machine learning. When we started the company it wasnt possible to do biology and engineering under the same roof. When we finally moved into a shared space we were able to learn each others lexicons, and we became more strongly aligned. And now that were all working separately, the bonds created in that process have helped us deal with things. We cant discuss technical details at our desks anymore, but weve learned new ways of working together. Its important to stay in sync as a team, and in a covid-19 world thats never felt more true.

TIM O'CONNELL

Founded Blendoor, a job-search platform that hides candidates names and photos in the initial stages to reduce unconscious bias.

I started coding at 13, and that has gotten me pretty far in my career (Stanford, MIT, Microsoft). I once viewed humanities and social science education as nice-to-haves but not need-to-haves. It wasnt until I came face to face with the harsh realities of inequity and the paradox of meritocracy that I realized that artificial intelligence is far from solving many of our most challenging problems as a human race (for example, xenophobia, sexism, racism, homophobia, impostor syndrome, and unconscious bias).

The externalities that influence creativity, adoption, and scale are often more important than the innovation itself. To be a successful innovator one has to be really in tune with whats happening in the world on a global scale (or be really lucky, or better yet both). Venture capital has shortened the learning curve for some innovators, but bias has limited access to venture capital for many. Unconscious bias is like an odorless gasits imperceptible to most, but pervasive and deadly.

To optimize the innovation ecosystem, institutions must invest more in leveling the playing field. Today and for much of the documented past, innovation has been reserved for the children of middle- and upper-class parents. (Research the founders of companies valued at over $1 billion.) We laud the proverb Necessity is the mother of invention, but the people who grow up needing the most, independent of their intelligence, are often left out of the innovation game. As with all games, the best players emerge when the barriers to entry are low, the rules/standards are equally enforced, and there is high transparency across the board.

Audre Lorde once wrote: The masters tools will never dismantle the masters house.

I am a short, melanin-enriched, queer female on planet Earth. In some ways its easier to be innovative when youre invisible, but at some point, you need tools to scale: capital, team, mentorship. The one thing I know now that I wish I had known earlier is that my path toward getting the tools I need looks a lot different from the paths of others. Its not better nor worsesimply different. The hardest part is carving it out. Now that I know my path isnt blockedrather, it just didnt existIm way better equipped to win.

COURTESY PHOTO

Founded DotLab, which makes diagnostic tests focused on womens health.

About a decade ago I worked at the White House Office of Science and Technology Policy, whose goal was to speed up the commercialization of technologies being developed in federally funded labs. While there I saw that some of the most important work done by the government involved things the media paid no attention tofor example, the way it could use investments in research and development to fuel private--sector innovation.

In 2009, the Obama administration released the Strategy for American Innovation. The idea behind it was to establish the critical nature of federal government support for R&D. In particular it stressed the spillover effects, or the idea that investments in such research end up being beneficial to people unrelated to the original investment. Or to put it another way, R&D investment is a public good. Analyses at the time suggested that in order to produce economic growth we should be doubling or quadrupling our R&D investments. Instead that spending has since been slashed, especially in basic research.

President Obama also launched a Lab to Market Initiative meant to speed the path to market for technologies stemming from government--funded research. There were also pilot programs designed to increase the use of government-funded R&D facilities by entrepreneurs, create incentives to commercialization, and improve, among other things, the impact of the Small Business Innovation Research (SBIR) program.

My own company, DotLab, ended up being a beneficiary. We develop novel molecular diagnostic tests for prevalent yet underserved diseases affecting womens health. Its notoriously difficult for this field of early--stage diagnostics to attract private investment, because of unclear regulatory pathways, low reimbursement rates, or resistance to change among physiciansor all of the above. Many promising diagnostic technologies never make it to patients because its so hard for these types of companies to get financing. A grant from the SBIR was critical to our early success. I cant be sure that wed be here today without it.

COURTESY PHOTO

Founded Ubiquitous Energy, which makes transparent solar cells that can be put on windows or device screens.

I used to imagine innovators as individuals, as most people probably dothe genius inventor divining solutions in a lab or garage. But this picture that people have is not only wrong; it hinders our ability to innovate effectively.

Eight years ago I cofounded Ubiquitous Energy, a company based on an innovation Id helped to launch from an MIT laba transparent solar cell that promised new ways of deploying solar technology, like windows that generate energy or consumer devices powered by their own displays. I learned that in the messy, scrappy world of tech startups, the key to innovation is to make it a team sport.

Taking any innovation from the lab to commercial reality requires engaging with all sorts of people. You need to work with engineering, R&D, business development, and sales teams, as well as investors, advisors, and customers. By thoughtfully designing teams and carefully tending to the connections among them, you ensure that innovation doesnt happen in a vacuum. If you isolate the engineering team you risk creating an innovative technology that doesnt have a customer. If you listen only to the customer you might conceive of a product that cant practically be made. Neglect investors and you can find yourself with a business plan that nobody wants to fund.

Working among people with competing priorities takes more effort. It means encouraging communication so theyre aware of each others needs as they generate new ideas. You have to find a way to invite these ideas in, make it okay for people to disagree respectfully, and encourage the flow of ideas among the various groups. You need each person to focus on his or her task, but not so much that it creates boundaries and kills any sense of creativity in the group.

Ive found that viewing innovation as a team sport instills a creative culture that makes an organization better. The innovations that result are far greater than anything that might have come from any one person operating independently.

CHRIS SCIACCA / IBM RESEARCH

Founded Somalias first incubator and start-up accelerator; now at IBM Research.

People tend to think innovation can be neatly placed into two categories: incremental or disruptive. They also assume that the only category that really matters is the disruptive kind, where you dramatically transform markets or introduce a novel product. And yes, disruptive innovations in CRISPR, quantum computing, or batteries are undoubtedly worth the headlines.

But Ive learned that there is immense value in incremental innovation. When you improve an existing product to cut costs, or when you make that product more efficient or user friendly, thats what pays the bills. And in fact those little innovations can give you the needed tailwind to go after the disruptive ideas, which can take years to incubate and bring to fruition. Never underestimate the importance of incremental improvements.

TIM O'CONNELL

Cofounded Imprint Energy, which is developing thin, flexible, and safe print- able batteries.

As a CEO of a startup, you get used to hearing no. You also face an endless succession of what feel like earth--shattering crises, like nearly running out of cash, losing a key customer, discovering a widespread product failureor having to shut down operations because of a global pandemic. But it turns out that these disasters can actually be good for you. In fact, Im not sure you can innovate without them. Heres what all our crises have taught me.

Its good to be uncomfortable. We once had a key customer request a battery capability that wed never deployed before. The customer made it clear that if we couldnt develop this capability theyd be less confident in our product. We wrestled with the risks, not least of which was the potential embarrassment if we couldnt meet the customers needs. We knew wed face many technical problems with no obvious solutions if we tried to pull it off. Yet we decided to try to satisfy the customer, even if it wasnt obvious at first how we could get it done. A few weeks later we delivered something beyond what the customer had asked for, and weve since grown this capability into a powerful sales tool and potential revenue streamnot to mention it strengthened our relationship with the customer.

Short-term failure is good. A few years ago our company began to scale up our manufacturing output in response to a customers need. In the process we discovered aberrations we hadnt seen during smaller-scale production. Our team dived into failure analysis, and we finally attributed the problem to a single material within the battery. Wed used this material for years, but now we needed a replacement. Once we deployed that change, the battery quality, reliability, and manufacturability drastically improved.

Its okay to be vulnerable. One of my hardest days as Imprints CEO was the day I found out I was pregnant. We were in the middle of raising a funding round, we had begun scaling our manufacturing output, and I had been traveling nonstop for a year. Until that day, I had assumed that my role as CEO was to exude strength and confidence. With the mounting pressure I was harder on myself than I needed to be, and now I had the added stress of being pregnant. I decided to acknowledge to my team that I was overwhelmed. They rallied together and found ways to operate more efficiently and communicate more effectively, supporting me to focus my time and leverage on our most pressing goals. This gave me not only the space to plan for the companys future, but also the resiliency to prepare for my own new normal: leading while becoming a first-time mother.

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Cell Harvesting Market 2020 Statistics Report with COVID-19 Effects on Industry by 2026 | PerkinElmer (US), Brandel (US), TOMTEC (US) – Jewish Life…

Posted: June 17, 2020 at 9:45 am

LOS ANGELES, United States:

The global Cell Harvesting market has been garnering remarkable momentum in the recent years. The steadily escalating demand due to improving purchasing power is projected to bode well for the global market. QY Researchs latest publication, titled global Cell Harvesting market, offers an insightful take on the drivers and restraints present in the market. It assesses the historical data pertaining to the global Cell Harvesting market and compares it to the current market trends to give the readers a detailed analysis of the trajectory of the market.

Get the Sample of this Report with Detail TOC and List of [emailprotected]https://www.qyresearch.com/sample-form/form/1533016/global-cell-harvesting-market

The research report covers the trends that are currently implemented by the major manufacturers in the Cell Harvesting market including adoption of new technology, government investments on R&D, shifting in perspective towards sustainability, and others. Additionally, the researchers have also provided the figures necessary to understand the manufacturer and its contribution to both regional and global market:

Key Players:

PerkinElmer (US),Brandel (US),TOMTEC (US),Pall Corporation (Danaher),Connectorate (Switzerland),Scinomix (US),ADSTEC (Japan),Sartorius,Terumo Corporation

Due to the pandemic, we have included a special section on the Impact of COVID 19 on the Cell Harvesting Market which would mention How the Covid-19 is Affecting the Cell Harvesting Industry, Market Trends and Potential Opportunities in the COVID-19 Landscape, Covid-19 Impact on Key Regions and Proposal for Cell Harvesting Players to Combat Covid-19 Impact.

The research report is broken down into chapters, which are introduced by the executive summary. Its the introductory part of the chapter, which includes details about global market figures, both historical and estimates. The executive summary also provides a brief about the segments and the reasons for the progress or decline during the forecast period. The insightful research report on the global Cell Harvesting market includes Porters five forces analysis and SWOT analysis to understand the factors impacting consumer and supplier behavior.

Market Segments Covered:

Global Cell Harvesting Market Segmentation by Product:ManualAutomated

Global Cell Harvesting Market Segmentation by Application:BiopharmaceuticalStem Cell Research

Regions Covered in the Global Cell Harvesting Market:

The Middle East and Africa (GCC Countries and Egypt) North America (the United States, Mexico, and Canada) South America (Brazil etc.) Europe (Turkey, Germany, Russia UK, Italy, France, etc.) Asia-Pacific (Vietnam, China, Malaysia, Japan, Philippines, Korea, Thailand, India, Indonesia, and Australia)

The report answers important questions that companies may have when operating in the global Cell Harvesting market. Some of the questions are given below:

What will be the size of the global Cell Harvesting market in 2025? What is the current CAGR of the global Cell Harvesting market? Which product is expected to show the highest market growth? Which application is projected to gain a lions share of the global Cell Harvesting market? Which region is foretold to create the most number of opportunities in the global Cell Harvesting market? Will there be any changes in market competition during the forecast period? Which are the top players currently operating in the global Cell Harvesting market? How will the market situation change in the coming years? What are the common business tactics adopted by players? What is the growth outlook of the global Cell Harvesting market?

The scope of the Report:

The report segments the global Cell Harvesting market on the basis of application, type, service, technology, and region. Each chapter under this segmentation allows readers to grasp the nitty-gritties of the market. A magnified look at the segment-based analysis is aimed at giving the readers a closer look at the opportunities and threats in the market. It also address political scenarios that are expected to impact the market in both small and big ways.The report on the global Cell Harvesting market examines changing regulatory scenario to make accurate projections about potential investments. It also evaluates the risk for new entrants and the intensity of the competitive rivalry.

Ask for Customized Report as per Your [emailprotected]https://www.qyresearch.com/customize-request/form/1533016/global-cell-harvesting-market

Strategic Points Covered in TOC:

1 Report Overview1.1 Study Scope1.2 Key Market Segments1.3 Players Covered: Ranking by Cell Harvesting Revenue1.4 Market by Type1.4.1 Global Cell Harvesting Market Size Growth Rate by Type: 2020 VS 20261.4.2 Manual1.4.3 Automated1.5 Market by Application1.5.1 Global Cell Harvesting Market Share by Application: 2020 VS 20261.5.2 Biopharmaceutical1.5.3 Stem Cell Research1.6 Study Objectives1.7 Years Considered

2 Global Growth Trends2.1 Global Cell Harvesting Market Perspective (2015-2026)2.2 Global Cell Harvesting Growth Trends by Regions2.2.1 Cell Harvesting Market Size by Regions: 2015 VS 2020 VS 20262.2.2 Cell Harvesting Historic Market Share by Regions (2015-2020)2.2.3 Cell Harvesting Forecasted Market Size by Regions (2021-2026)2.3 Industry Trends and Growth Strategy2.3.1 Market Top Trends2.3.2 Market Drivers2.3.3 Market Challenges2.3.4 Porters Five Forces Analysis2.3.5 Cell Harvesting Market Growth Strategy2.3.6 Primary Interviews with Key Cell Harvesting Players (Opinion Leaders)

3 Competition Landscape by Key Players3.1 Global Top Cell Harvesting Players by Market Size3.1.1 Global Top Cell Harvesting Players by Revenue (2015-2020)3.1.2 Global Cell Harvesting Revenue Market Share by Players (2015-2020)3.1.3 Global Cell Harvesting Market Share by Company Type (Tier 1, Tier 2 and Tier 3)3.2 Global Cell Harvesting Market Concentration Ratio3.2.1 Global Cell Harvesting Market Concentration Ratio (CR5 and HHI)3.2.2 Global Top 10 and Top 5 Companies by Cell Harvesting Revenue in 20193.3 Cell Harvesting Key Players Head office and Area Served3.4 Key Players Cell Harvesting Product Solution and Service3.5 Date of Enter into Cell Harvesting Market3.6 Mergers & Acquisitions, Expansion Plans

4 Market Size by Type (2015-2026)4.1 Global Cell Harvesting Historic Market Size by Type (2015-2020)4.2 Global Cell Harvesting Forecasted Market Size by Type (2021-2026)

5 Market Size by Application (2015-2026)5.1 Global Cell Harvesting Market Size by Application (2015-2020)5.2 Global Cell Harvesting Forecasted Market Size by Application (2021-2026)

6 North America6.1 North America Cell Harvesting Market Size (2015-2020)6.2 Cell Harvesting Key Players in North America (2019-2020)6.3 North America Cell Harvesting Market Size by Type (2015-2020)6.4 North America Cell Harvesting Market Size by Application (2015-2020)

7 Europe7.1 Europe Cell Harvesting Market Size (2015-2020)7.2 Cell Harvesting Key Players in Europe (2019-2020)7.3 Europe Cell Harvesting Market Size by Type (2015-2020)7.4 Europe Cell Harvesting Market Size by Application (2015-2020)

8 China8.1 China Cell Harvesting Market Size (2015-2020)8.2 Cell Harvesting Key Players in China (2019-2020)8.3 China Cell Harvesting Market Size by Type (2015-2020)8.4 China Cell Harvesting Market Size by Application (2015-2020)

9 Japan9.1 Japan Cell Harvesting Market Size (2015-2020)9.2 Cell Harvesting Key Players in Japan (2019-2020)9.3 Japan Cell Harvesting Market Size by Type (2015-2020)9.4 Japan Cell Harvesting Market Size by Application (2015-2020)

10 Southeast Asia10.1 Southeast Asia Cell Harvesting Market Size (2015-2020)10.2 Cell Harvesting Key Players in Southeast Asia (2019-2020)10.3 Southeast Asia Cell Harvesting Market Size by Type (2015-2020)10.4 Southeast Asia Cell Harvesting Market Size by Application (2015-2020)

11 India11.1 India Cell Harvesting Market Size (2015-2020)11.2 Cell Harvesting Key Players in India (2019-2020)11.3 India Cell Harvesting Market Size by Type (2015-2020)11.4 India Cell Harvesting Market Size by Application (2015-2020)

12 Central & South America12.1 Central & South America Cell Harvesting Market Size (2015-2020)12.2 Cell Harvesting Key Players in Central & South America (2019-2020)12.3 Central & South America Cell Harvesting Market Size by Type (2015-2020)12.4 Central & South America Cell Harvesting Market Size by Application (2015-2020)

13 Key Players Profiles13.1 PerkinElmer (US)13.1.1 PerkinElmer (US) Company Details13.1.2 PerkinElmer (US) Business Overview13.1.3 PerkinElmer (US) Cell Harvesting Introduction13.1.4 PerkinElmer (US) Revenue in Cell Harvesting Business (2015-2020))13.1.5 PerkinElmer (US) Recent Development13.2 Brandel (US)13.2.1 Brandel (US) Company Details13.2.2 Brandel (US) Business Overview13.2.3 Brandel (US) Cell Harvesting Introduction13.2.4 Brandel (US) Revenue in Cell Harvesting Business (2015-2020)13.2.5 Brandel (US) Recent Development13.3 TOMTEC (US)13.3.1 TOMTEC (US) Company Details13.3.2 TOMTEC (US) Business Overview13.3.3 TOMTEC (US) Cell Harvesting Introduction13.3.4 TOMTEC (US) Revenue in Cell Harvesting Business (2015-2020)13.3.5 TOMTEC (US) Recent Development13.4 Pall Corporation (Danaher)13.4.1 Pall Corporation (Danaher) Company Details13.4.2 Pall Corporation (Danaher) Business Overview13.4.3 Pall Corporation (Danaher) Cell Harvesting Introduction13.4.4 Pall Corporation (Danaher) Revenue in Cell Harvesting Business (2015-2020)13.4.5 Pall Corporation (Danaher) Recent Development13.5 Connectorate (Switzerland)13.5.1 Connectorate (Switzerland) Company Details13.5.2 Connectorate (Switzerland) Business Overview13.5.3 Connectorate (Switzerland) Cell Harvesting Introduction13.5.4 Connectorate (Switzerland) Revenue in Cell Harvesting Business (2015-2020)13.5.5 Connectorate (Switzerland) Recent Development13.6 Scinomix (US)13.6.1 Scinomix (US) Company Details13.6.2 Scinomix (US) Business Overview13.6.3 Scinomix (US) Cell Harvesting Introduction13.6.4 Scinomix (US) Revenue in Cell Harvesting Business (2015-2020)13.6.5 Scinomix (US) Recent Development13.7 ADSTEC (Japan)13.7.1 ADSTEC (Japan) Company Details13.7.2 ADSTEC (Japan) Business Overview13.7.3 ADSTEC (Japan) Cell Harvesting Introduction13.7.4 ADSTEC (Japan) Revenue in Cell Harvesting Business (2015-2020)13.7.5 ADSTEC (Japan) Recent Development13.8 Sartorius13.8.1 Sartorius Company Details13.8.2 Sartorius Business Overview13.8.3 Sartorius Cell Harvesting Introduction13.8.4 Sartorius Revenue in Cell Harvesting Business (2015-2020)13.8.5 Sartorius Recent Development13.9 Terumo Corporation13.9.1 Terumo Corporation Company Details13.9.2 Terumo Corporation Business Overview13.9.3 Terumo Corporation Cell Harvesting Introduction13.9.4 Terumo Corporation Revenue in Cell Harvesting Business (2015-2020)13.9.5 Terumo Corporation Recent Development

14 Analysts Viewpoints/Conclusions

15 Appendix15.1 Research Methodology15.1.1 Methodology/Research Approach15.1.2 Data Source15.2 Disclaimer15.3 Author Details

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Cell Harvesting Market 2020 Statistics Report with COVID-19 Effects on Industry by 2026 | PerkinElmer (US), Brandel (US), TOMTEC (US) - Jewish Life...

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UCLA receives nearly $14 million from NIH to investigate gene therapy to combat HIV – Newswise

Posted: June 17, 2020 at 9:45 am

Newswise UCLA researchers and colleagues have received a $13.65 million grant from the National Institutes of Health to investigate and further develop an immunotherapy known as CAR T, which uses genetically modified stem cells to target and destroy HIV.

The five-year grant, part of an NIH effort to develop gene-engineering technologies to cure HIV/AIDS, will fund a collaboration among UCLA; CSL-Behring, a biotechnology company in the United States and Australia; and the University of WashingtonFred Hutchinson Cancer Research Center.

Scott Kitchen, an associate professor of medicine in the division of hematology and oncology, and Irvin Chen, director of theUCLA AIDS Instituteat theDavid Geffen School of Medicine at UCLA,are leading the effort. The project will build on their previous research using CAR T therapy to combat the virus, which is constantly mutating and difficult to beat.

The overarching goal of our proposed studies is to identify a newgene therapy strategy to safely and effectively modify a patients own stem cells to resist HIV infection andsimultaneously enhance their ability to recognize and destroy infected cells in the body in hopes of curing HIV infection, said Kitchen, who also directs the humanized mouse core laboratory for UCLAsCenter for AIDS ResearchandJonsson Comprehensive Cancer Center.It is a huge boost to our efforts at UCLA and elsewhere to find a creative strategy to defeat HIV.

The only known cure of an HIV-infected person was announced in 2008. The famous Berlin patient received a stem cell transplant from a donor whose cells naturally lacked a crucial receptor that HIV binds to in order to kill cells and destroy the immune system. The main problems with this approach, the researchers say, are that the donor and recipient have to be highly matched often a rare event and that it often fails to produce a sufficient amount of HIV-protected cells that can clear the virus from the body.

Transplantation of blood-forming stem cells has been the only treatment strategy that has resulted ina functional cure for HIV infection, Kitchen said. Over 13 years after the first successfully cured HIV-infected patient, there is a substantial need to develop strategies that are capable of being used on everyone with HIV infection.

One of those strategies, CAR T, has been the subject ofongoing researchat UCLA by Chen, Kitchen and others. This approach involves genetically engineering a patients own blood-forming stem cells to carry genes for chimeric antigen receptors, or CARs. Once these stem cells are modified and transplanted back into the patient, they form specialized infection-fighting white blood cells known as T cells in this case, CAR T cells that specifically seek out and kill HIV-infected cells. In a recent study, the UCLA scientists found that engineered CAR T cells not only destroyed infected cells but also lived for more than two years the length of the study.

The thinking behind the NIH-funded project, the researchers say, is that a combination of CARs and broadly neutralizing antibodies may be a long-lasting, perhaps permanent, cure for HIV.

Our work under the NIH grant will provide a great deal of insight into ways the immune response can be modified to better fight HIV infection, said Chen, who is a professor of medicine and of microbiology, immunology and molecular genetics at the Geffen School of Medicine. The development of this unique strategy that allows the body to develop multiple ways to attack HIV could have an impact on other diseases as well, including the development of similar approaches targeting other types of chronic viral infections and cancers.

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Adipose Tissue-derived Stem Cell Therapy Market Statistics, Facts and Figures, Investment Trends, Key Players and Forecast by 2026 – Weekly Wall

Posted: June 17, 2020 at 9:45 am

Los Angeles, United State: QY Research recently published a research report titled, Global Adipose Tissue-derived Stem Cell Therapy Market Research Report 2020-2026. The research report attempts to give a holistic overview of the Adipose Tissue-derived Stem Cell Therapy market by keeping the information simple, relevant, accurate, and to the point. The researchers have explained each aspect of the market thoroughmeticulous research and undivided attention to every topic. They have also provided data in statistical data to help readers understand the whole market. The Adipose Tissue-derived Stem Cell Therapy Market report further provides historic and forecast data generated through primary and secondary research of the region and their respective manufacturers.

Get Full PDF Sample Copy of Report: (Including Full TOC, List of Tables & Figures, Chart) https://www.qyresearch.com/sample-form/form/1798005/covid-19-impact-on-global-adipose-tissue-derived-stem-cell-therapy-market

Global Adipose Tissue-derived Stem Cell Therapy Market report section gives special attention to the manufacturers in different regions that are expected to show a considerable expansion in their market share. Additionally, it underlines all the current and future trends that are being adopted by these manufacturers to boost their current market shares. This Adipose Tissue-derived Stem Cell Therapy Market report Understanding the various strategies being carried out by various manufacturers will help reader make right business decisions.

Key Players Mentioned in the Global Adipose Tissue-derived Stem Cell Therapy Market Research Report: , AlloCure, Antria, Celgene Corporation, Cellleris, Corestem, Cytori Therapeutics, Intrexon, Mesoblast, Pluristem Therapeutics, Tissue Genesis, BioRestorative Therapies, Celltex Therapeutics Corporation, iXCells Biotechnologies, Pluristem Therapeutics, Cyagen, Lonza Adipose Tissue-derived Stem Cell Therapy

Global Adipose Tissue-derived Stem Cell Therapy Market Segmentation by Product: , Therapeutic Application, Research Application

Global Adipose Tissue-derived Stem Cell Therapy Market Segmentation by Application: , Autologous Stem Cells, Allogeneic Stem Cells Adipose Tissue-derived Stem Cell Therapy

The Adipose Tissue-derived Stem Cell Therapy market is divided into the two important segments, product type segment and end user segment. In the product type segment it lists down all the products currently manufactured by the companies and their economic role in the Adipose Tissue-derived Stem Cell Therapy market. It also reports the new products that are currently being developed and their scope. Further, it presents a detailed understanding of the end users that are a governing force of the Adipose Tissue-derived Stem Cell Therapy market.

In this chapter of the Adipose Tissue-derived Stem Cell Therapy Market report, the researchers have explored the various regions that are expected to witness fruitful developments and make serious contributions to the markets burgeoning growth. Along with general statistical information, the Adipose Tissue-derived Stem Cell Therapy Market report has provided data of each region with respect to its revenue, productions, and presence of major manufacturers. The major regions which are covered in the Adipose Tissue-derived Stem Cell Therapy Market report includes North America, Europe, Central and South America, Asia Pacific, South Asia, the Middle East and Africa, GCC countries, and others.

Key questions answered in the report:

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Table od Content

1 Report Overview1.1 Study Scope1.2 Key Market Segments1.3 Players Covered: Ranking by Adipose Tissue-derived Stem Cell Therapy Revenue1.4 Covid-19 Implications on Market by Type1.4.1 Global Adipose Tissue-derived Stem Cell Therapy Market Size Growth Rate by Type: 2020 VS 20261.4.2 Autologous Stem Cells1.4.3 Allogeneic Stem Cells1.5 Market by Application1.5.1 Global Adipose Tissue-derived Stem Cell Therapy Market Share by Application: 2020 VS 20261.5.2 Therapeutic Application1.5.3 Research Application1.6 Coronavirus Disease 2019 (Covid-19): Adipose Tissue-derived Stem Cell Therapy Industry Impact1.6.1 Covid-19 Impact: Global GDP Growth, 2019, 2020 and 2021 Projections1.6.2 Covid-19 Impact: Commodity Prices Indices1.6.3 Covid-19 Impact: Global Major Government Policy 1.7 Study Objectives 1.8 Years Considered 2 Global Growth Trends2.1 Covid-19 Implications on Global Adipose Tissue-derived Stem Cell Therapy Market Perspective (2015-2026)2.2 Covid-19 Implications on Global Adipose Tissue-derived Stem Cell Therapy Growth Trends by Regions2.2.1 Adipose Tissue-derived Stem Cell Therapy Market Size by Regions: 2015 VS 2020 VS 20262.2.2 Adipose Tissue-derived Stem Cell Therapy Historic Market Share by Regions (2015-2020)2.2.3 Adipose Tissue-derived Stem Cell Therapy Forecasted Market Size by Regions (2021-2026) 2.3 Industry Trends and Growth Strategy 2.3.1 Market Top Trends 2.3.2 Market Drivers2.3.3 Market Challenges2.3.4 Porters Five Forces Analysis2.3.5 Adipose Tissue-derived Stem Cell Therapy Market Growth Strategy2.3.6 Primary Interviews with Key Adipose Tissue-derived Stem Cell Therapy Players (Opinion Leaders) 3 Covid-19 Implications on Competition Landscape by Key Players3.1 Global Top Adipose Tissue-derived Stem Cell Therapy Players by Market Size3.1.1 Global Top Adipose Tissue-derived Stem Cell Therapy Players by Revenue (2015-2020)3.1.2 Global Adipose Tissue-derived Stem Cell Therapy Revenue Market Share by Players (2015-2020)3.1.3 Global Adipose Tissue-derived Stem Cell Therapy Market Share by Company Type (Tier 1, Tier 2 and Tier 3)3.2 Global Adipose Tissue-derived Stem Cell Therapy Market Concentration Ratio3.2.1 Global Adipose Tissue-derived Stem Cell Therapy Market Concentration Ratio (CR5 and HHI)3.2.2 Global Top 10 and Top 5 Companies by Adipose Tissue-derived Stem Cell Therapy Revenue in 20193.3 Adipose Tissue-derived Stem Cell Therapy Key Players Head office and Area Served3.4 Key Players Adipose Tissue-derived Stem Cell Therapy Product Solution and Service3.5 Date of Enter into Adipose Tissue-derived Stem Cell Therapy Market3.6 Mergers & Acquisitions, Expansion Plans 4 Covid-19 Implications on Market Size by Type (2015-2026)4.1 Global Adipose Tissue-derived Stem Cell Therapy Historic Market Size by Type (2015-2020)4.2 Global Adipose Tissue-derived Stem Cell Therapy Forecasted Market Size by Type (2021-2026) 5 Covid-19 Implications on Market Size by Application (2015-2026)5.1 Global Adipose Tissue-derived Stem Cell Therapy Market Size by Application (2015-2020)5.2 Global Adipose Tissue-derived Stem Cell Therapy Forecasted Market Size by Application (2021-2026) 6 North America Impact of COVID-196.1 North America Adipose Tissue-derived Stem Cell Therapy Market Size (2015-2020)6.2 Adipose Tissue-derived Stem Cell Therapy Key Players in North America (2019-2020)6.3 North America Adipose Tissue-derived Stem Cell Therapy Market Size by Type (2015-2020)6.4 North America Adipose Tissue-derived Stem Cell Therapy Market Size by Application (2015-2020) 7 Europe Impact of COVID-197.1 Europe Adipose Tissue-derived Stem Cell Therapy Market Size (2015-2020)7.2 Adipose Tissue-derived Stem Cell Therapy Key Players in Europe (2019-2020)7.3 Europe Adipose Tissue-derived Stem Cell Therapy Market Size by Type (2015-2020)7.4 Europe Adipose Tissue-derived Stem Cell Therapy Market Size by Application (2015-2020) 8 China Impact of COVID-198.1 China Adipose Tissue-derived Stem Cell Therapy Market Size (2015-2020)8.2 Adipose Tissue-derived Stem Cell Therapy Key Players in China (2019-2020)8.3 China Adipose Tissue-derived Stem Cell Therapy Market Size by Type (2015-2020)8.4 China Adipose Tissue-derived Stem Cell Therapy Market Size by Application (2015-2020) 9 Japan Impact of COVID-199.1 Japan Adipose Tissue-derived Stem Cell Therapy Market Size (2015-2020)9.2 Adipose Tissue-derived Stem Cell Therapy Key Players in Japan (2019-2020)9.3 Japan Adipose Tissue-derived Stem Cell Therapy Market Size by Type (2015-2020)9.4 Japan Adipose Tissue-derived Stem Cell Therapy Market Size by Application (2015-2020) 10 Southeast Asia Impact of COVID-1910.1 Southeast Asia Adipose Tissue-derived Stem Cell Therapy Market Size (2015-2020)10.2 Adipose Tissue-derived Stem Cell Therapy Key Players in Southeast Asia (2019-2020)10.3 Southeast Asia Adipose Tissue-derived Stem Cell Therapy Market Size by Type (2015-2020)10.4 Southeast Asia Adipose Tissue-derived Stem Cell Therapy Market Size by Application (2015-2020) 11 India Impact of COVID-1911.1 India Adipose Tissue-derived Stem Cell Therapy Market Size (2015-2020)11.2 Adipose Tissue-derived Stem Cell Therapy Key Players in India (2019-2020)11.3 India Adipose Tissue-derived Stem Cell Therapy Market Size by Type (2015-2020)11.4 India Adipose Tissue-derived Stem Cell Therapy Market Size by Application (2015-2020) 12 Central & South America Impact of COVID-1912.1 Central & South America Adipose Tissue-derived Stem Cell Therapy Market Size (2015-2020)12.2 Adipose Tissue-derived Stem Cell Therapy Key Players in Central & South America (2019-2020)12.3 Central & South America Adipose Tissue-derived Stem Cell Therapy Market Size by Type (2015-2020)12.4 Central & South America Adipose Tissue-derived Stem Cell Therapy Market Size by Application (2015-2020) 13Key Players Profiles13.1 AlloCure13.1.1 AlloCure Company Details13.1.2 AlloCure Business Overview and Its Total Revenue13.1.3 AlloCure Adipose Tissue-derived Stem Cell Therapy Introduction13.1.4 AlloCure Revenue in Adipose Tissue-derived Stem Cell Therapy Business (2015-2020))13.1.5 AlloCure Recent Development and Reaction to COVID-1913.2 Antria13.2.1 Antria Company Details13.2.2 Antria Business Overview and Its Total Revenue13.2.3 Antria Adipose Tissue-derived Stem Cell Therapy Introduction13.2.4 Antria Revenue in Adipose Tissue-derived Stem Cell Therapy Business (2015-2020)13.2.5 Antria Recent Development and Reaction to COVID-1913.3 Celgene Corporation13.3.1 Celgene Corporation Company Details13.3.2 Celgene Corporation Business Overview and Its Total Revenue13.3.3 Celgene Corporation Adipose Tissue-derived Stem Cell Therapy Introduction13.3.4 Celgene Corporation Revenue in Adipose Tissue-derived Stem Cell Therapy Business (2015-2020)13.3.5 Celgene Corporation Recent Development and Reaction to COVID-1913.4 Cellleris13.4.1 Cellleris Company Details13.4.2 Cellleris Business Overview and Its Total Revenue13.4.3 Cellleris Adipose Tissue-derived Stem Cell Therapy Introduction13.4.4 Cellleris Revenue in Adipose Tissue-derived Stem Cell Therapy Business (2015-2020)13.4.5 Cellleris Recent Development and Reaction to COVID-1913.5 Corestem13.5.1 Corestem Company Details13.5.2 Corestem Business Overview and Its Total Revenue13.5.3 Corestem Adipose Tissue-derived Stem Cell Therapy Introduction13.5.4 Corestem Revenue in Adipose Tissue-derived Stem Cell Therapy Business (2015-2020)13.5.5 Corestem Recent Development and Reaction to COVID-1913.6 Cytori Therapeutics13.6.1 Cytori Therapeutics Company Details13.6.2 Cytori Therapeutics Business Overview and Its Total Revenue13.6.3 Cytori Therapeutics Adipose Tissue-derived Stem Cell Therapy Introduction13.6.4 Cytori Therapeutics Revenue in Adipose Tissue-derived Stem Cell Therapy Business (2015-2020)13.6.5 Cytori Therapeutics Recent Development and Reaction to COVID-1913.7 Intrexon13.7.1 Intrexon Company Details13.7.2 Intrexon Business Overview and Its Total Revenue13.7.3 Intrexon Adipose Tissue-derived Stem Cell Therapy Introduction13.7.4 Intrexon Revenue in Adipose Tissue-derived Stem Cell Therapy Business (2015-2020)13.7.5 Intrexon Recent Development and Reaction to COVID-1913.8 Mesoblast13.8.1 Mesoblast Company Details13.8.2 Mesoblast Business Overview and Its Total Revenue13.8.3 Mesoblast Adipose Tissue-derived Stem Cell Therapy Introduction13.8.4 Mesoblast Revenue in Adipose Tissue-derived Stem Cell Therapy Business (2015-2020)13.8.5 Mesoblast Recent Development and Reaction to COVID-1913.9 Pluristem Therapeutics13.9.1 Pluristem Therapeutics Company Details13.9.2 Pluristem Therapeutics Business Overview and Its Total Revenue13.9.3 Pluristem Therapeutics Adipose Tissue-derived Stem Cell Therapy Introduction13.9.4 Pluristem Therapeutics Revenue in Adipose Tissue-derived Stem Cell Therapy Business (2015-2020)13.9.5 Pluristem Therapeutics Recent Development and Reaction to COVID-1913.10 Tissue Genesis13.10.1 Tissue Genesis Company Details13.10.2 Tissue Genesis Business Overview and Its Total Revenue13.10.3 Tissue Genesis Adipose Tissue-derived Stem Cell Therapy Introduction13.10.4 Tissue Genesis Revenue in Adipose Tissue-derived Stem Cell Therapy Business (2015-2020)13.10.5 Tissue Genesis Recent Development and Reaction to COVID-1913.11 BioRestorative Therapies10.11.1 BioRestorative Therapies Company Details10.11.2 BioRestorative Therapies Business Overview and Its Total Revenue10.11.3 BioRestorative Therapies Adipose Tissue-derived Stem Cell Therapy Introduction10.11.4 BioRestorative Therapies Revenue in Adipose Tissue-derived Stem Cell Therapy Business (2015-2020)10.11.5 BioRestorative Therapies Recent Development and Reaction to COVID-1913.12 Celltex Therapeutics Corporation10.12.1 Celltex Therapeutics Corporation Company Details10.12.2 Celltex Therapeutics Corporation Business Overview and Its Total Revenue10.12.3 Celltex Therapeutics Corporation Adipose Tissue-derived Stem Cell Therapy Introduction10.12.4 Celltex Therapeutics Corporation Revenue in Adipose Tissue-derived Stem Cell Therapy Business (2015-2020)10.12.5 Celltex Therapeutics Corporation Recent Development and Reaction to COVID-1913.13 iXCells Biotechnologies10.13.1 iXCells Biotechnologies Company Details10.13.2 iXCells Biotechnologies Business Overview and Its Total Revenue10.13.3 iXCells Biotechnologies Adipose Tissue-derived Stem Cell Therapy Introduction10.13.4 iXCells Biotechnologies Revenue in Adipose Tissue-derived Stem Cell Therapy Business (2015-2020)10.13.5 iXCells Biotechnologies Recent Development and Reaction to COVID-1913.14 Pluristem Therapeutics10.14.1 Pluristem Therapeutics Company Details10.14.2 Pluristem Therapeutics Business Overview and Its Total Revenue10.14.3 Pluristem Therapeutics Adipose Tissue-derived Stem Cell Therapy Introduction10.14.4 Pluristem Therapeutics Revenue in Adipose Tissue-derived Stem Cell Therapy Business (2015-2020)10.14.5 Pluristem Therapeutics Recent Development and Reaction to COVID-1913.15 Cyagen10.15.1 Cyagen Company Details10.15.2 Cyagen Business Overview and Its Total Revenue10.15.3 Cyagen Adipose Tissue-derived Stem Cell Therapy Introduction10.15.4 Cyagen Revenue in Adipose Tissue-derived Stem Cell Therapy Business (2015-2020)10.15.5 Cyagen Recent Development and Reaction to COVID-1913.16 Lonza10.16.1 Lonza Company Details10.16.2 Lonza Business Overview and Its Total Revenue10.16.3 Lonza Adipose Tissue-derived Stem Cell Therapy Introduction10.16.4 Lonza Revenue in Adipose Tissue-derived Stem Cell Therapy Business (2015-2020)10.16.5 Lonza Recent Development and Reaction to COVID-19 14Analysts Viewpoints/Conclusions 15Appendix15.1 Research Methodology15.1.1 Methodology/Research Approach15.1.2 Data Source15.2 Disclaimer15.3 Author Details

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QY Research established in 2007, focus on custom research, management consulting, IPO consulting, industry chain research, data base and seminar services. The company owned a large basic data base (such as National Bureau of statistics database, Customs import and export database, Industry Association Database etc), experts resources (included energy automotive chemical medical ICT consumer goods etc.

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Adipose Tissue-derived Stem Cell Therapy Market Statistics, Facts and Figures, Investment Trends, Key Players and Forecast by 2026 - Weekly Wall

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AgeX Therapeutics : and Pluristyx Announce Manufacturing, Marketing, and Distribution Agreement to Expand Access to Clinical-Grade Human Pluripotent…

Posted: June 17, 2020 at 9:45 am

ALAMEDA - AgeX Therapeutics, Inc. ('AgeX': NYSE American: AGE), a biotechnology company developing therapeutics for human aging and regeneration, and Pluristyx, Inc. (Seattle, WA), an advanced therapy tools and services company serving customers in the rapidly growing fields of regenerative medicine and cellular and gene therapies, today announced they have entered into a Manufacturing, Marketing, and Distribution Agreement through which Pluristyx will undertake these activities on behalf of AgeX with respect to AgeX's research and clinical-grade ESI brand human embryonic stem cells, sometimes referred to as hESCs.

The agreement builds on Pluristyx's strategy to manufacture, market, and distribute high-quality standardized Ready-to-Use and Ready-to-Differentiate pluripotent stem cells to industry and academic scientists intent on developing therapeutic products to treat human disease. AgeX's ESI hESC lines are distinguished for being the first clinical-grade hESC lines created under current Good Manufacturing Practice (cGMP). The AgeX ESI hESC lines are listed on the National Institutes of Health (NIH) Stem Cell Registry and are among the best characterized and documented stem cell lines available worldwide.

The agreement is a key step in AgeX's licensing and collaboration strategy to facilitate industry and academic access to its hESC lines, its PureStem cell derivation and manufacturing platform, and its UniverCyte immunotolerance technology in order to generate near- and long-term revenues.

'A recent FDA IND clearance for a biotech company to begin a human trial for a cell therapy candidate derived from an AgeX ESI hESC line has amplified interest from industry and academia to utilize our cells in regenerative medicine. It is AgeX's goal to make its cell lines the gold standard when it comes to therapeutic products derived from pluripotent stem cells. We are delighted to be working with the Pluristyx team given their extensive cGMP manufacturing experience with pluripotent stem cells,' said Dr. Nafees Malik, Chief Operating Officer of AgeX.

'Pluristyx is excited to be working with AgeX and their ESI hESC lines. As AgeX intends to make their cell lines the gold standard, our aim is to disrupt and redefine stem cell therapy manufacturing with our proprietary, high-density format, Ready-to-Use and Ready-to-Differentiate hESC lines, which will dramatically reduce both cost and time in translating revolutionary therapies from bench to bedside,' said Dr. Benjamin Fryer, CEO of Pluristyx.

Academic and biopharma organizations will need to obtain separate commercial licenses from AgeX in order to advance their cellular product candidates generated from AgeX hESC lines into human clinical trials and commercialization. AgeX retains all rights to manufacture its own in-house cellular products as well as to extend license rights to other third parties.

About AgeX Therapeutics

AgeX Therapeutics, Inc. (NYSE American: AGE) is focused on developing and commercializing innovative therapeutics for human aging. Its PureStem and UniverCyte manufacturing and immunotolerance technologies are designed to work together to generate highly defined, universal, allogeneic, off-the-shelf pluripotent stem cell-derived young cells of any type for application in a variety of diseases with a high unmet medical need. AgeX has two preclinical cell therapy programs: AGEX-VASC1 (vascular progenitor cells) for tissue ischemia and AGEX-BAT1 (brown fat cells) for Type II diabetes. AgeX's revolutionary longevity platform induced Tissue Regeneration (iTR) aims to unlock cellular immortality and regenerative capacity to reverse age-related changes within tissues. AGEX-iTR1547 is an iTR-based formulation in preclinical development. HyStem is AgeX's delivery technology to stably engraft PureStem cell therapies in the body. AgeX's core product pipeline is intended to extend human healthspan. AgeX is seeking opportunities to establish licensing and collaboration arrangements around its broad IP estate and proprietary technology platforms and therapy product candidates.

About Pluristyx

Established in 2018, Pluristyx Inc. is a privately held, early-stage company providing a complete cell manufacturing solution. As an advanced therapy tools company, Pluristyx helps companies and researchers solve manufacturing challenges in the field of drug development, regenerative medicine, and cell and gene therapy. Pluristyx is led by a team with decades of industry experience each with specific expertise in key areas needed to develop and manufacture pluripotent stem cells. Pluristyx provides know how in every stage of the process from cell banking through scale-up of clinical grade material as well as all aspects of process development and manufacturing.

Forward-Looking Statements for AgeX

Certain statements contained in this release are 'forward-looking statements' within the meaning of the Private Securities Litigation Reform Act of 1995. Any statements that are not historical fact including, but not limited to statements that contain words such as 'will,' 'believes,' 'plans,' 'anticipates,' 'expects,' 'estimates' should also be considered forward-looking statements. Forward-looking statements involve risks and uncertainties. Actual results may differ materially from the results anticipated in these forward-looking statements and as such should be evaluated together with the many uncertainties that affect the business of AgeX Therapeutics, Inc. and its subsidiaries, particularly those mentioned in the cautionary statements found in more detail in the 'Risk Factors' section of AgeX's most recent Annual Report on Form 10-K and Quarterly Report on Form 10-Q filed with the Securities and Exchange Commissions (copies of which may be obtained at http://www.sec.gov). Subsequent events and developments may cause these forward-looking statements to change. In addition, with respect to AgeX's Manufacturing, Marketing and Distribution Agreement with Pluristyx there is no assurance that (i) Pluristyx will generate significant sales of AgeX ESI hESC lines, or (ii) AgeX will derive significant revenue from sales of ESI hESC lines by Pluristyx. AgeX specifically disclaims any obligation or intention to update or revise these forward-looking statements as a result of changed events or circumstances that occur after the date of this release, except as required by applicable law.

Contact:

Andrea Park

Email: apark@agexinc.com

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AgeX Therapeutics : and Pluristyx Announce Manufacturing, Marketing, and Distribution Agreement to Expand Access to Clinical-Grade Human Pluripotent...

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Close to 2,000 Faculty, Staff Return to Work as Some Harvard Labs Resume Research Operations | News – Harvard Crimson

Posted: June 17, 2020 at 9:45 am

Nearly 2,000 faculty and staff members returned to scientific research laboratories at Harvard over the past week the first large scale return to work since campus shut down in mid-March due to the coronavirus pandemic.

University Provost Alan M. Garber 76 announced on May 4 that Harvard would begin a phased reopening of Harvards research labs, which he described as urgent.

The return to research operations is overseen by a Lab Reopening Committee, initially formed by Vice Provost for Research Richard D. McCullough in collaboration with Dean of Science Christopher J. Stubbs at Garber's request.

The labs operate in shifts and use physical distancing and personal protective protocols. They are modeled after guidelines used by University labs dedicated to COVID-19 research, which have remained open as essential work.

Naina Kurup, a postdoctoral fellow in the Chemistry Department, wrote in an email that the guidelines have contributed to a sense of security, though there has been a learning curve for certain requirements, like avoiding common spaces and completing online check-ins.

Nevertheless, Kurup wrote that she and others in the lab are slowly finding our groove again."

It's been exciting to see my worms come back to life again so I can start the experiments I was planning at home! she wrote.

Though researchers are social distancing, Professor of Engineering and Applied Sciences Conor J. Walsh said his labs ability to return to in-person experiments is positive, noting its work is experimental in nature and cannot be done at home.

For us, we're not able to do the types of research we are without being in the lab, he said.

Stem Cell and Regenerative Biology Professor Richard T. Lee 79, a former Crimson editor, said the reopening of his lab is crucial because its work relies on experiments.

We could write up some papers and write proposals, but we weren't getting new data, he said. We were very much shut down by the shutdown.

Still short of full capacity, Lee said researchers must be much more strategic about time spent in the lab.

We're trying to get those answers now as quickly as we can, he said. We're not at full capacity and so we have to be very careful about every person, hour in the lab.

Though Lee is overseeing the lab, he said that he himself has not returned to the lab, since his presence would take up one of the density spots the number of researchers authorized to work in the lab at a given time and.

Mohammed Mostafizur Rahman, a postdoctoral fellow in the Department of Molecular and Cellular Biology, said that he spent much of last week in preparation for future experiments.

For all the work that we shut down, we need time to ramp up as well, he said. This first week hasn't been really much work as much as prep for the work a lot of animal breeding, getting animals ready, getting your reagents ready.

Leonardo A. Sepulveda Duran, a postdoctoral fellow in the Chemistry Department, said that he, too, is seeking to be strategic about his work in case the pandemic closes labs again.

I'm focusing on just trying to get the most data I can in a few next months, so if we have to go into lockdown again, I can do the analysis of the data remotely, the same way I've been doing, Sepulveda Duran said. I imagine this is going to happen several times until we get a vaccine.

For now, though, most said they are happy to be back to work.

As an experimentalist, there's no other place you want to be than in your lab, Rahman said.

Staff writer Camille G. Caldera can be reached at camille.caldera@thecrimson.com. Follow her on Twitter @camille_caldera.

Staff writer Michelle G. Kurilla can be reached at michelle.kurilla@thecrimson.com. Follow her on Twitter @MichelleKurilla.

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Close to 2,000 Faculty, Staff Return to Work as Some Harvard Labs Resume Research Operations | News - Harvard Crimson

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